I-Acekardol 100 yisidakamizwa esivela eqenjini lezidakamizwa ezingezona ze-anti -idalidal, okuyinto eyi-ejenti ephumelelayo ye-antiplatelet. Isetshenziselwa ukwelapha nokuvikela izifo eziningi zohlelo lwethambo nenhliziyo.
Igama Lezwe elingafanele
Ukulungiselela kwe-INN: acetylsalicylic acid.
I-ATX
Ikhodi ye-ATX: B01AC06
Khipha amafomu nokwakheka
Umuthi ukhishwa kuphela kwifomu lethebhulethi.
Amaphilisi
Izibhebhe zihlanganiswe nensimbi ekhethekile yokuvikela, encibilika kahle emathunjini. Ithebhulethi eyodwa ingaqukatha i-50, 100 noma i-300 mg ye-acetylsalicylic acid.
Izithako ezingeziwe: i-povidone, isitashi, i-lactose encane, iselula, i-magnesium stearate, i-talc, inani elincane le-titanium dioxide kanye namafutha ahlanzekile we-castor.
Izibhebhe ziyindilinga, zimhlophe, zimbozwe ngegobolondo elimhlophe. Kugcwele emabhulini akhethekile izingcezu eziyi-10 inye. Iphakheji iqukethe kusuka ku-1 kuya ku-5 amabhulashi anjalo nemiyalo.
Amaconsi
Ayitholakali njengamaconsi.
Powder
Kwifomu le-powder, umkhiqizo awutholakali.
I-Acecardol 100 isetshenziselwa ukwelapha nokuvikela izifo eziningi zohlelo lwethambo nenhliziyo.
Isixazululo
Umuthi awukhululwa ngesisombululo.
Amakhandlela
Ayitholakali ngefomu le-capsule.
Amafutha
Lesi sidakamizwa asikaze sikhishwe ngendlela yamafutha.
Uhlobo olungekho
Kunamathebhulethi e-Acecardol kuphela. Zonke ezinye izindlela okuhloswe ngazo ukukhishwa azisebenzi kulo muthi.
Isenzo se-Pharmacological
I-acetylsalicylic acid inomphumela we-antiplatelet. Umshini wayo usekelwe ekuvinjelweni okungenakuphikwa kwe-cycloo oxygenase. Njengomphumela walokhu, i-blockade esheshayo ye-thromboxane synthesis iyenzeka. Kulokhu, inqubo yokuhlanganisa iplatelet iyacindezelwa.
Kwimithamo ephezulu, i-asidi ingakhiqiza imiphumela yokulwa nokuvuvukala, i-analgesic ne-antipyretic.
I-Pharmacokinetics
Ngemuva kokufaka iphilisi ngaphakathi, into esebenzayo imunwa ngokushesha evela emgodini wokugaya ukudla. Imunca kahle futhi iba inqubo yokugaya umzimba ngokwengxenye. Ngenxa yalokhu, kwakhiwa i-metabolite eyinhloko - i-salicylic acid, eqhubeka nokuguqulwa kwayo esibindini. Ukuhlushwa okuphezulu kakhulu kwe-ASA ku-plasma yegazi kubonwa kungakapheli isigamu sehora ngemuva kokuthatha iphilisi.
I-Bioavailability kanye namandla okubopha ezinhlakeni zamaprotheni ziphakeme impela. Isigamu sempilo singamahora amathathu. Igcotshwe ngokuhlunga kwe-renal ngendlela yama-metabolites amakhulu.
Yini edingekayo
Imvamisa imiselwe ukwelashwa kwezifo eziningi zenhliziyo (i-angina engazinzile) nezinhloso ze-prophylactic. Izinkomba eziphambili ezisetshenziselwa ukuvimbela:
- ukuthuthukiswa kwe-infyoctional eyingozi neyesibili ye-myocardial;
- unhlangothi lapho kunengozi ye-cerebrovascular;
- ukubonakala kwe-thromboembolism ngemuva kokusebenza okuhlukahlukene;
- i-thrombosis yemithambo ejulile ne-pulmonary artery.
Contraindication
Imithetho eqinile yokusetshenziswa kwalesi sidakamizwa ifaka phakathi:
- ukopha kwesisu;
- ukuguguleka kanye nezilonda zesisu nezinye izitho zesistimu yokugaya ukudla;
- isifuba somoya;
- Izifo ezibonakaliswa ukungasebenzi okwanele kwezinso nesibindi;
- ukwehluleka kwenhliziyo okungapheli;
- ukuthatha i-methotrexate;
- isikhathi sokukhulelwa nokuncelisa ibele;
- iminyaka efinyelela eminyakeni eyi-18;
- ukuntuleka kwe-lactase nokungabekezelelwa kwe-lactose;
- hypersensitivity ngamanye ku-acetylsalicylic acid.
Konke lokhu kuphambana kufanele kubhekwe ngaphambi kokuqala ukwelashwa ngezidakamizwa.
Ngokunakekela
Kufanele kuqashelwe lapho uphuza umuthi we-gout, ulcer peptic, ngaphambi kokungenelela okuhlongozwayo kokuhlinzwa, kanye nasendabeni yokwelashwa okuhambisana nama-anticoagulants.
Amathebulethi kufanele athathwe ngokushesha ngaphambi kokudla, isikhathi esingu-1 ngosuku.
Ungayithatha kanjani i-Acecardol 100
Amathebulethi kufanele athathwe ngokushesha ngaphambi kokudla, isikhathi esingu-1 ngosuku. Kungcono ukwenza lokhu ngasikhathi sinye ekuseni. Umuthi wenzelwe ukwelashwa isikhathi eside.
Ukuvimbela ukuthuthukiswa kwe-infutction ye-myocardial acute, i-100 mg ngosuku noma ama-300 mg njalo olunye usuku olusetshenziswayo. Ukuze uthole kahle, kunconywa ukuhlafuna amaphilisi.
Ngokuvimbela ukushaya kwenhliziyo kwesibili, kusetshenziswa isilinganiso esifanayo somuthi. Nge-angina engazinzile, kunconywa ukuthatha kusuka kuma-100 kuye kwangama-300 mg ngosuku, kuya ngobucayi be-pathology.
Ekuvinjelweni kwe-ischemic stroke kanye nengozi ye-cerebrovascular, i-100-300 mg yomuthi inqunyelwe ngosuku. Ukuvimbela i-thromboembolism ngemuva kokuhlinzwa kubandakanya ukusetshenziswa kwe-300 mg ye-ASA ngosuku. Ekuvinjelweni kwe-venous thrombosis ne-pulmonary embolism, kubalulekile ukuphuza i-100 mg ngosuku noma ama-300 mg njalo ngosuku.
Kungenzeka yini ukuthi uphuze umuthi onesifo sikashukela
Umuthi osezingeni eliphansi uvunyelwe ukuwuthatha nesifo sikashukela. Umphumela wokuthatha i-insulin uzothuthukiswa kancane ngenxa yomthelela we-hypoglycemic emzimbeni we-acetylsalicylic acid kumithamo ephezulu.
Imiphumela emibi
Lapho usebenzisa lo muthi, imiphumela emibi ehlukahlukene ihlala ivela. Zithinta cishe zonke izitho nezinhlelo.
Amapheshana wesisu
Ukusuka ohlelweni lokugaya ukudla kuvame ukwenzeka: ukushisa kwenhliziyo, isicanucanu, ukugabha, ukopha kwesisu.
Izitho zeHematopoietic
Ngenxa yezakhiwo ze-antiplatelet ze-ASA, ubungozi bokuphuma kwegazi bukhuphuka, ngoba ukuhlangana kweplatelet kuyancipha. I-hememic anemia ivame ukwenzeka.
Isistimu yezinzwa ephakathi
Ubuhlungu bekhanda nesiyezi esinzima. Iziguli kwesinye isikhathi zinaka ukubukeka kwe-tinnitus kanye nokwehla komsebenzi wokuzwa.
Uma usebenzisa i-Acecardol, kungcono ukukhawulela ukuzishayela.
Kusuka ohlelweni lokuphefumula
Ezimweni ezinzima, i-bronchospasm iba.
Allergies
Ukungezwani komuthi kuvela kaningi. Iziguli zikhononda ngokuqhuma kwesikhumba, ukulunywa. I-edema ye-Quincke, i-urticaria, i-diathesis, ne-rhinitis iyakhula. Ezimweni ezinzima kakhulu, ukushaqeka kwe-anaphylactic kungaqala.
Umthelela ekhonweni lokulawula izindlela
Uma usebenzisa i-Acecardol, kungcono ukukhawulela ukuzishayela; I-ASA ithinta ukugxilisa ukunaka kanye nesivinini sokuphendula kwengqondo okudingekayo ezimweni eziphuthumayo.
Imiyalo ekhethekile
I-Acetylsalicylic acid icasulisa ukuthuthukiswa kokuphazamiseka kwe-hypersensitivity, phakathi kwalokhu ukuhlaselwa kwe-asthma ye-bronchial kanye ne-bronchospasm kuvame ukwenzeka. Izici zobungozi zibandakanya iziguli ezinomkhuhlane we-hay fever, i-polyposis yamakhala kanye nezifo eziningi zokuphefumula ezingelapheki.
Ukuvinjwa kokuhlanganiswa kweplatelet kuholela engcupheni eyengeziwe yokopha lapho uhlinzwa.
Ngokusetshenziswa isikhathi eside kwalesi sidakamizwa ngemithamo ephansi, i-gout ingaqhubeka ibe yimbi, ikakhulukazi kwiziguli ezincishisiwe i-uric acid. Ukweqisa umthamo owodwa ovumelekile womuthi kungaholela ekukhuleni kokopha kwesisu.
Sebenzisa ebudaleni
Kufanele kuqashelwe lapho usebenzisa umuthi ezigulini esezikhulile. Kulesi sikhathi, ingozi yokwanda kwezinkinga zenhliziyo iyanda. Ngaphezu kwalokho, imiphumela emibi emibi ivame ukubonwa lapho uphuza umuthi. Lokhu kuphakamisa ukuthi uma kukhona ushintsho esimweni sempilo, umthamo wehliselwa osezingeni elifanele.
Ukuphathwa kwe-Acecardol ezinganeni eziyi-100
Iminyaka yezingane ibhekwa njengokuphikisana nokusetshenziswa kwaleli thuluzi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Onke ama-trimesters abonakala ngokungahambi kahle kwawo ekwakhiweni kwesibeletho lapho uthatha ama-salicylates. Ngakho-ke, ukugwema ukuthuthukiswa kokulimazeka kwenhliziyo nokukhubazeka kwenhliziyo, umuthi wenqatshelwe ukuthatha ekuqaleni kokukhulelwa. Ukuqokwa kwama-salicylates ku-trimester yesithathu kungavusa amandla okusebenza okujwayelekile, ukopha okunzima kumama nakuma-fetus.
Izinto ezisebenzayo zidlulela kubisi lwebele ngokushesha. Ngakho-ke, ngesikhathi sokwelashwa ngezidakamizwa, kungcono ukwenqaba ukuncelisa ibele.
Ukweqisa
Uma ngephutha uthatha umthamo omkhulu womuthi, ingozi yokuthola ukopha kwangaphakathi ikhuphuka kakhulu. Ngokuyisisekelo, nge-overdose, imiphumela eminingi emibi iyanda.
Uma kwenzeka kusetshenziswa i-overdose, i-lavage esiswini, kuthathwa imithamo eminingi yamalahle ocushiwe kanye nabanye o-sorbents.
Kulokhu, isiguli sidinga ukulaliswa esibhedlela ngokuphuthumayo. Ukuqunjelwa kwesisu kwenziwa, kuthathwa imithamo eminingi yekhabhoni esebenzayo namanye ama-sorbents. I-diresis ephoqelekile kanye ne-hemodialysis yenziwa ukuze kubuyiselwe ngokushesha ukulingana kwamanzi-electrolyte kanye ne-acid-base body.
Ukuxhumana nezinye izidakamizwa
Ngenxa yokuncipha kokuvunyelwa kwe-creatinine kanye nokwephulwa kokubopha kwayo amaprotheni ngenkathi kuthatha i-ASA, umphumela weMethotrexate uyanda. Umphumela we-anticoagulants ne-heparin engaqondile uqiniswa ukungasebenzi kahle kweplatelet.
Ukusebenza kokusetshenziswa kwama-antiplatelet agents, ama-digoxin nama-hypoglycemic agents, kanye ne-valproic acid.
Lapho kuhlanganiswa ne-ASA, ukusebenza kwe-ACE inhibitors, eminye imishanguzo ye-diuretics ne-uricosuric iyancipha.
Ukuhambisana notshwala
Ungathathi lesi sidakamizwa notshwala, ngoba umphumela wayo ohlelweni lwezinzwa uyanda, izimpawu zokudakwa ziyaqina, isikhathi sokuphuma kwegazi siyandiswa.
Ama-Analog
Kunezichazi eziningi eziphambili zalo muthi, ezifana ngazo zombili ukwakheka komphumela wokwelapha. Okuvame kakhulu phakathi kwabo:
- Acetylsalicylic acid;
- I-Thrombopol;
- I-CardiASK;
- I-Thrombotic ACC;
- Aspirin;
- Aspicore
- Upsarin UPSA.
I-analogue yesidakamizwa ingaba yiTrombopol yezidakamizwa.
Izimo zokuphumula Acecardol 100 kusuka ekhemisi
Umuthi usesigabeni somphakathi. Ingathengwa kunoma iyiphi ikhemisi ngaphandle kwemithi ekhethekile evela kudokotela.
Malini
Intengo iphansi. Amathebulethi angathengwa kuma-ruble angama-50. ukupakisha.
Izimo zokugcina zomuthi
Kuyadingeka ukugcina umkhiqizo wezokwelapha endaweni evikelwe ezinganeni ngangokunokwenzeka, endaweni yokushisa yasekamelweni. Kungcono ukuthi amaphilisi agcinwe emaphaketheni awo okuqala.
Isikhathi sokuphelelwa yisikhathi
Akukwedlule iminyaka eyi-4 kusuka ngosuku lokwenziwa, okufanele kukhonjiswe kwiphakheji yangempela.
Umkhiqizi we-Acecardol 100
I-SYNTHESIS OJSC - inkampani ehlangene ye-Kurgan yamalungiselelo wemikhiqizo yezokwelapha nemikhiqizo (iRussia).
Ukubuyekezwa ku-Acecardol 100
U-Alexey, oneminyaka engama-42, uSamara
Nginezinkinga zokukhuluphala ngokweqile, ngakho-ke sengisengozini yokuhlaselwa yimivimbo nokuhlaselwa yisifo senhliziyo. Udokotela unikeze amaphilisi e-Acecardol ukuvimbela. Sekuphele unyaka ngiwathatha. Ngigculisekile ngempumelelo yomuthi. Futhi intengo vele ayikwazi kodwa sicela. Ekuqaleni kuphela lapho bekunezinhlungu zekhanda, angizwanga eminye imiphumela emibi ngokwami.
U-Alexandra, oneminyaka engama-30, uSochi
Ngikhuphuke kakhulu ukugcwala kwegazi. Udokotela uthe lokhu kusongela ukwakheka kweziqalo zegazi kanye nokuthuthukiswa kwezifo zohlelo lwezinhliziyo. Ngiqale ukuthatha amaphilisi e-Acecardol. Bahambe kahle. Kancane kancane igazi laqala ukuba notshwala. Umphumela wokwelashwa waneliswa.
U-Olga, oneminyaka engama-43, Izhevsk
Ube nezinkinga "ngokuya" nge-gynecology. Nginegazi elanele le-viscous, ngakho-ke ngaphambi kokuhlinzwa, udokotela wanquma amaphilisi e-Acecardol. Izinsuku ezimbalwa ngaphambi kokuhlinzwa, ngabathatha. Kepha emva kwayo ngaqala ukuba nokuphuma kwangaphakathi okuqinile. Bathe lokhu kusabela okunjalo ku-acetylsalicylic acid. Ngakho-ke, angincomi noma ngubani ukuthi athathe umuthi onjalo ngaphandle kokuhlola bonke ubungozi obukhona.
