I-Amoxicillin 250 isidakamizwa esilwa ne-antibacterial esingesigaba se-penicillin futhi siyi-anti-synthetic antibiotic.
Ngokwesakhiwo samakhemikhali, lesi sidakamizwa sisondele kakhulu e-Ampicillin, kepha sihlukile kuso ngokuba khona kweqembu le-hydroxo, elithuthukisa i-bioavailability. Enye into ebalulekile yesidakamizwa ukungqiniswa okwandisiwe emiphumeleni yejusi yesisu. Lapho amathumbu engashintshiwe, i-Amoxicillin imunca kahle, isakazeka ngokushesha ngezicubu zomzimba, ngaleyo ndlela inikeze umphumela omkhulu wokwelapha.
Igama Lezwe elingafanele
I-Amoxicillin 250 isidakamizwa esilwa ne-antibacterial esingesigaba se-penicillin futhi siyi-anti-synthetic antibiotic.
Umuthi unegama elifanayo lezentengiselwano kanye nolwezinye izizwe - i-Amoxicillin.
I-ATX
Ngokuya ngokwehlukaniswa kwamazwe ngezidakamizwa (i-ATX), i-Amoxicillin inekhodi i-J01CA04.
Khipha amafomu nokwakheka
Umuthi utholakala ngezindlela ezi-3:
- amaphilisi
- amaphilisi;
- izinduku zokumiswa.
Isithako esikhulu esisebenzayo ohlotsheni ngalunye lomuthi yi-amoxicillin trihydrate.
Isithako esikhulu esisebenzayo ohlotsheni ngalunye lomuthi yi-amoxicillin trihydrate.
Amaphilisi
Ama-Dragees abunjwe nge-capsule futhi asengozini evela ohlangothini olu-1. Ababizi yilezi:
- i-talc;
- i-magnesium stearate;
- isitashi samazambane.
Amacwecwe ahlanganiswe emaphaketheni okulimaza ama-10 ama-pc., Ipakethe eli-1 liqukethe amaphakethe ama-2 nemiyalo esetshenzisiwe.
Amakhandlela
I-capsule yisitsha esinsundu ngombala obhalwe ngombhalo ovela ku- "AMOXI 250", ugcwele impuphu emhlophe. Njengoba izinto ezisizayo yile:
- i-magnesium stearate;
- i-talc;
- i-carmuazine;
- idayimane eliluhlaza okwesibhakabhaka;
- ophuzi we-orange;
- i-iron oxide;
- titanium dioxide;
- i-gelatin.
I-Amoxicillin capsule isitsha se-tan esigcwele i-powder emhlophe.
Amaphilisi ahlanganiswa emaphaketheni ama-blister enziwe nge-aluminium foil nefilimu le-PVC, ama-pc ayi-10 lilinye. lilinye. Ibhokisi lingaqukatha amaphakheji ayi-1, 2 noma ama-3 nemiyalo esetshenzisiwe. Amakhebhula angafakwa futhi ezimbizeni zepulasitiki zama-10, 20 noma ama-30 ama-pcs.
Ukumiswa
I-granrate ifakwe ku-100 ml vials. I-granule ngayinye ifaka into esetshenziswayo nezinto ezisizayo ezinjengalezi:
- i-carmuazine sodium;
- i-sodium benzoate;
- i-sodium citrate;
- gum;
- i-simethicone S184;
- ukunambitha i-passionflower edliwayo;
- sucrose.
Isenzo se-Pharmacological
I-Amoxicillin isidakamizwa esine-bactericidal: inhloso yayo enkulu ukucindezela ikhono lamagciwane aphile. Umuthi uthinta ama-enzyme akha izindonga zeseli ze-microorganism, azicekele phansi, okubangela ukufa kwawo.
Umuthi uthinta ama-enzyme akha izindonga zeseli ze-microorganism, azicekele phansi.
I-Amoxicillin ibhekana nezinhlobo zamagciwane ezinjengalezi:
- staphylococci;
- gonococci;
- streptococci;
- ISalmonella
- UShigella.
Kodwa-ke, umuthi awukwazi ukubizwa ngokuthi uwonkewonke: awuthinti amagciwane akhiqiza i-beta-lactamase (le nto ihlukanisa umuthi olwa namagciwane). Ukuvikela umuthi esenzweni se-beta-lactamase, i-clavulanic acid ivame ukufakwa ekwakhiweni kwayo.
I-Pharmacokinetics
I-Amoxicillin inokufakwa ngokushesha futhi okuphezulu (ngaphezu kwama-90%), kanti ukudla kuyakuthinta ukufakwa komuthi. Ngemuva kokuphathwa ngomlomo, isidakamizwa siqala ukusebenza ngemuva kwemizuzu engu-15-30. Ukuhlaziywa kwe-plasma ephezulu kakhulu kufinyelelwa ngemuva kwamahora we-1-2, futhi umphumela wokwelapha uthatha cishe amahora angama-8. Njengoba sekushiwo, umuthi usatshalaliswa kuwo wonke izicubu. Ekugxilweni okuphezulu, umuthi utholakala kulamanzi kanye nolwelwesi lwama-mucous cishe lwazo zonke izitho zangaphakathi, ku-bile, ku-adipose ngisho nezicubu zamathambo.
Umuthi ubandakanyeka ngokwengxenye ezinqubweni ze-metabolic. Isigamu sempilo amahora angama-1-1,5. Okungashintshiwe, u-70% wento udalulwa izinso, 10-20% - ngesibindi. Uma imvume ye-creatinine incishiswa yaba ngu-15 ml ngomzuzwana (okhombisa umsebenzi wezinso ongasebenzi kahle), khona-ke isikhathi sempilo-sikhuphuka siye emahoreni ayi-8.
Yini esiza?
I-Amoxicillin isiza ngokwelashwa kwezifo zemvelaphi yamagciwane futhi inqunyelwe izifo:
- Ipheshana lokuphefumula eliphakeme nelingaphansi. Njengo:
- i-sinusitis;
- i-sinusitis
- pharyngitis;
- abezindaba ze-otitis;
- i-laryngitis;
- i-tonsillitis;
- i-bronchitis;
- inyumoniya
- Uhlelo lwe-genitourinary. Njengo:
- cystitis
- i-pyelonephritis;
- i-jade;
- i-gonorrhea;
- urethritis;
- i-pyelitis;
- i-endometritis.
- Amapheshana wesisu. Njengo:
- cholecystitis;
- i-enterocolitis;
- i-peritonitis;
- udayi;
- cholangitis;
- umkhuhlane we-typhoid;
- i-salmonellosis.
- Isikhumba. Njengo:
- i-bacterial dermatosis;
- erysipelas;
- i-leptospirosis;
- impetigo.
I-Amoxicillin 250 isetshenziselwa ukwelapha i-meningitis.
Umuthi futhi unqunyelwe ekwelapheni:
- i-meningitis;
- i-listeriosis;
- sepsis;
- i-endocarditis;
- i-borreliosis.
I-Amoxicillin isetshenziswa ihlanganiswe ne-metronidazole ekwelapheni i-exacerbations of gastric and duodenal ulcers kanye ne-gastritis engamahlalakhona. Zombili lezi zidakamizwa zimisa ngempumelelo ukukhula kwamagciwane abangela lezi zifo.
Contraindication
I-Amoxicillin ayinqunyelwe ezimweni lapho isiguli:
- omncane kuneminyaka emithathu;
- iku-1st trimester yokukhulelwa;
- Umama ongumhlengikazi;
- uhlushwa ukwehluleka okukhulu kwe-reso;
- inokuphakama okukhulu kokugaya ukudla;
- uhlushwa i-allergic diathesis;
- unesifo se-mononucleosis esithathelwanayo;
- ngigula yi-lymphocytic leukemia;
- unesifo somoya (asthma);
- inomlando we-colitis ehambisana nemithi elwa namagciwane;
- uhlushwa ukungabekezelelwa komuntu ngamunye kuya ku-Amoxicillin noma ezinye izidakamizwa eziseqenjini le-penicillin.
Awukwazi ukusebenzisa lesi sidakamizwa okukhulunywa ngaso ku-1st trimester yokukhulelwa.
Ngokunakekela
Ngokuqapha, umuthi kufanele usetshenziswe ne:
- ukukhulelwa
- isifo sezinso
- umlando wokopha;
- izifo zesisu;
- ukuthambekela kokusabela komzimba.
Ungayithatha kanjani i-Amoxicillin 250?
Kubantu abadala, umuthi unqunywe izikhathi ezingama-500 mg kathathu ngosuku. Ngenkambo enzima kakhulu yezinqubo zokutheleleka nokuvuvukala, umthamo owodwa ukhushulwa waba ngu-750-1000 mg.
Ekwelapheni izifo ezithambile nezivuvukala zezifo zesibeletho, kanye nezifo zomgudu wesibeletho kanye nomgudu wesisu, umthamo obekiwe ungaba ngu-1000-1500 mg, okufanele uphuzwe kaningi ngosuku, noma ngo-1500-2000 mg, othathwa kathathu ngosuku.
Umthamo ekwelashweni kwe-leptospiriosis ngu-500-750 mg. Thatha umuthi amahlandla ama-4 ngosuku.
I-Salmonellosis iphathwa isikhathi eside kunayo yonke: umuthi uphuzwa kathathu ngosuku nge-1500-2000 mg okungenani izinsuku eziyi-14.
Ekwelapheni i-gonorrhea emadodeni, umuthi uthathwa isikhathi esingu-1, kepha ngethamo elikhulu le-3000 mg.
Ukuze uvikele i-endocarditis ezimweni zokungenelela kokuhlinzwa, i-Amoxicillin ithathwa izikhathi ezi-2 ngosuku: isikhathi esingu-1 ihora ngaphambi kokuhlinzwa (3000-4000 mg) futhi, uma kunesidingo, ngemuva komthamo wamahora we-8-9, thatha umthamo ophindaphindwe. Uma isiguli sinezinkinga zokwehluleka kwezinso, isikhathi sokwanda sikhuphuka saba amahora angama-12.
Uma imvume ye-creatinine iphansi kakhulu, umthamo kumele wehliswe.
Ekwelashweni kwe-gonorrhea emadodeni, umuthi uthathwa isikhathi esingu-1, kepha ngethamo elikhulu le-3000 mg, abesifazane badinga ukuthatha isilinganiso esifanayo kabili.
Ngaphambi noma ngemuva kokudla
I-Amoxicillin ithathwa ngomlomo, igezwe phansi nge-1 tbsp. amanzi. Ukuthatha umuthi kuvunyelwe ngaphambi nangemva kokudla, kuyilapho ithebhulethi ingagwinya iphelele, ihlafunwe noma ihlukaniswe izingxenye. Amakhandlela kufanele aphathwe ephelele.
Zingaki izinsuku zokuphuza?
Ngokuya kokutholwa, isikhathi sokwelashwa sisukela ezinsukwini ezi-5 kuye kwezingu-12. Nge-salmonellosis, isikhathi sokwelashwa sisuka emavikini amabili kuya enyangeni eyi-1.
Ukuthatha umuthi wesifo sikashukela
Ukwelashwa kwe-Amoxicillin kwesifo sikashukela kuvunyelwe, kepha kusetshenziswa kuphela amaphilisi noma amaphilisi. Ukumiswa kuqukethe i-sucrose, ngakho akufanele kuthathwe.
Imiphumela emibi ye-Amoxicillin 250
Ukwelashwa kwe-Amoxicillin akuvamile ukuthi kuhambisane nemiphumela emibi, noma kunjalo, kungenzeka.
Amapheshana wesisu
Ukusuka emiphumeleni emibi yesisu sephepha kungenzeka ngohlobo lwe:
- isicanucanu
- ukuhlanza
- isifo sohudo
- ushintsho ekunambithekeni;
- dysbiosis;
- ukungasebenzi kahle kwesibindi;
- i-enterocolitis.
I-Amoxicillin ingadala ukugabha.
Isistimu yezinzwa ephakathi
Imiphumela emibi kungenzeka ngo:
- ukweqile;
- Isiyezi
- ikhanda;
- ukuphazamiseka kokuziphatha;
- Ukudana
- ukuqwasha
- ukudideka kokwazi;
- iminyakazo.
Kusuka ohlelweni lwezinhliziyo
Ezimweni ezingavamile, i-tachycardia kanye nokushoda komoya kungenzeka.
Allergies
Umuthi ungadala:
- i-urticaria;
- ukuvuvukala
- i-rhinitis;
- i-erythema;
- i-conjunctivitis;
- izinhlungu ezihlangene
- umkhuhlane
- isikhumba.
Umthelela ekhonweni lokulawula izindlela
Ngoba ukusetshenziswa kwe-amoxicillin kungadala ukusabela okungekuhle kusuka ohlelweni lwezinzwa ngendlela yokuphazamiseka kokuziphatha, ukuyaluza, isiyezi, lapho-ke inqubo yokwelashwa, izindlela ezengeziwe zokuphepha kufanele zibhekwe lapho kushayela izimoto nokulawula izindlela eziyinkimbinkimbi. Kungcono ukuyeka ngokuphelele imisebenzi engaba yingozi isikhathi sokwelashwa.
Imiyalo ekhethekile
Lapho welapha nge-Amoxicillin, kuyadingeka ukuthi ngaso sonke isikhathi ubheke isimo sesibindi, izinso nezitho ezakha igazi.
I-Amoxicillin ivame ukunciphisa ukusebenza kwezindlela zokuvimbela inzalo.
Ngesikhathi sokulashwa nge-Amoxicillin, umthetho oyinhloko wokuthatha umuthi kufanele ube njalo: umphumela wezidakamizwa uthatha amahora angama-8, futhi umthamo ngamunye olandelayo kufanele uthathwe ngezikhathi ezithile zamahora angama-8. Uma umuthi kufanele uthathwe amahlandla ama-4 ngosuku, khona-ke isikhathi sokuphakathi komthamo kufanele kube amahora ayi-6.
Ngemuva kokunyamalala kwezimpawu zesifo, umuthi uthathwa okungenani izinsuku ezi-2 ukuhlanganisa umphumela.
Lapho uthatha inzalo yokuvimbela inzalo yomlomo equkethe i-estrogen, ngasikhathi sinye se-Amoxicillin, kumele kuthathelwe izinyathelo zokuvimbela inzalo, ngoba umuthi olwa namagciwane unciphisa ukusebenza kwawo.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
I-Amoxicillin ivunyelwe ngesikhathi sokukhulelwa kuma-trimesters e-2 ne-3, kodwa kuphela uma inzuzo kumama iphakeme kunokulimaza ingane. Kwi-trimester ye-1 futhi ngenkathi uncelisa, ukusetshenziswa kwe-antibiotic kuyenqatshelwe (umuthi ungena ebisini futhi kungaholela ku-dysbiosis enganeni).
Ungayinikeza kanjani i-Amoxicillin ezinganeni ezingama-250?
Uma isiguli simdala kuneminyaka eyi-10 futhi sinesisindo esingaphezu kwamakhilogremu angama-40, khona-ke sinikezwa imithamo efanayo njengomuntu omdala. Okuhlukile ukuvimbela i-endocarditis ngesikhathi sokuhlinzwa. Kulokhu, umthamo uhanjisiwe.
Uma ingane ingaphansi kweminyaka eyi-10, khona-ke imithamo ingaphansi: ezinganeni ezineminyaka emi-5 kuye kweli-10, umuthi unqunywe ngo-250 mg ngosuku, ezinganeni ezineminyaka emi-3 kuya kwengama-5 - 125 mg.
Kuzona zozimbili lezi zidakamizwa, isidakwa sithathwa kathathu ngosuku. Ezinganeni ezincane, imithamo ibalwa ngokuya ngesisindo somzimba.
Ezigulini ezingaphansi kweminyaka eyi-10, kungcono ukusebenzisa ukumiswa. Ama-granules kufanele ahlanjululwe ngqo ebhodleleni le-ekhemisi, engeza amanzi kulolo uphawu odongeni lomkhumbi, bese okuqukethwe kukhululiwe.
Ezigulini ezingaphansi kweminyaka engu-10 ubudala, kungcono ukusebenzisa ukumiswa kwe-Amoxicillin.
Umkhiqizo ophelile ungagcinwa endaweni yokushisa yasekamelweni izinsuku eziyi-14. Isipuni sokulinganisa esinamathiselwe sizokuvumela ukukala ngokunembile umthamo owuthandayo.
I-overdose ye-Amoxicillin 250
I-drug overdose ibonakaliswa yizimpawu ezilandelayo:
- isifo sohudo esibuhlungu;
- isicanucanu
- ukuhlanza
- ukomisa.
Indlela yokwelashwa ifaka lezi zinyathelo ezilandelayo:
- Ukuhanjiswa kwesisu.
- Ukwemukelwa kwe-carbon eyenziwe nge-carbon ne-saline laxatives.
- Ukubuyiselwa kwemali esele ye-electrolyte.
- Ukugeza igazi nge-hemodialysis.
Ukuxhumana nezinye izidakamizwa
I-Amoxicillin ayinqunyelwe kanye namaqembu emithi ye-bacteriostatic, ngoba iphazamisa ukufakwa kwe-antibiotic.
Lamaqembu afaka:
- ama-sulfonamides;
- ama-tetracyclines;
- ama-macrolides.
Ngaphezu kwalokho, ukumuncwa kwe-Amoxicillin kubethelwa:
- ama-laxatives;
- i-glucosamine;
- ama-antacid;
- glycosides.
I-Ascorbic acid nezidakamizwa ze-bactericidal zithuthukisa umphumela we-Amoxicillin.
I-Amoxicillin ayinqunyelwe ngokuhlangana nama-macrolides.
Ukuhambisana notshwala
Ukwemukelwa kwanoma yiziphi izidakamizwa ezilwa namagciwane, kubandakanya ne-Amoxicillin, notshwala abuhambelani.
Ama-Analog
Izithonjana ze-Amoxicillin yilezi:
- Flemoxin Solutab (Netherlands);
- I-Amoxicillin Sandoz (Switzerland);
- I-Ospamox (Switzerland);
- U-Amosin (Russia);
- I-Amoksiklav (iSlovenia).
Imibandela yekhefu lekhemisi
Ngokusho kwemiyalo esetshenzisiwe, umuthi kumele uchithelwe emakhemisi kuphela ngomuthi odingekayo.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Umuthi ungathengwa ekhemisi ngaphandle kwencwadi kadokotela.
Amoxicillin 250 intengo
Noma yiziphi izindlela ezi-3 zokukhishwa komuthi ezingabizi. Izindleko zamathebulethi ayi-10 cishe ama-ruble angama-30., Amaphilisi angama-20 - ama-ruble angama-60.
Umuthi ungathengwa ekhemisi ngaphandle kwencwadi kadokotela.
Ukupakisha kubiza amagremu ayi-10 ukulungiselela ukumiswa.
Izimo zokugcina zomuthi
Amacwecwe namaphilisi kufanele agcinwe ngaphandle kokukhanya kwelanga endaweni yokushisa engeqi ku-25 ° C, endaweni eyomile engenakufinyeleleka ezinganeni. I-granate yokulungiselela ukumiswa igcinwa ngaphansi kwezimo ezifanayo, kepha ekushiseni kwe + 15 ... + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshalofu yamathebulethi yiminyaka emi-2, ama-capsule kanye no granule wokulungiselela ukumiswa - iminyaka emi-3.
Umkhiqizi
Umuthi osesimweni samathebulethi ukhiqizwa eRussia, ngesimo samaphilisi eBelarus, ebhizinisini elihlanganyelwe laseDashi-Belarusian, ngendlela yamalayini wokulungiselela ukumiswa eSerbia.
Ukubuyekezwa kodokotela neziguli ku-Amoxicillin 250
U-Oleg, oneminyaka engama-42 ubudala, opolaryngologist, oneminyaka engu-14 yesipiliyoni, uVladimir: "Ngivame ukunquma i-Amoxicillin ekwelashweni kwezifo ze-streptococcal, ngezifo ezinzima zomphimbo, izindlebe, njll. Kubantu abadala nasezinganeni. Umuthi ubekezelelwa kahle, imiphumela emibi ayiveli, ukululama kuyashesha. "
UMaria, oneminyaka engama-45 ubudala, enesifo sokuqaqanjelwa kwezinso, osekuneminyaka engu-19 asebenza eMoscow: "Ngivame ukunquma i-Amoxicillin ekwelashweni kwe-gastritis ihlangana nezinye izidakamizwa. I-antibiotic isebenza kahle, futhi isithinta kancane esiswini. Kodwa-ke, ukusetshenziswa kwama-probiotic kuyisidingo sokuqala sokwelashwa."
U-Ana, oneminyaka engama-36 ubudala, uNovorossiysk: "Ngihlushwa i-gastritis engapheli kusukela ngisemncane. Noma imiphi imithi elwa namagciwane kufanele ithathwe kuphela ihlanganiswe neBioflora. Nakulokhu futhi, iBioflora yayingatholakali, futhi i-Amoxicillin kwadingeka ukuthi idakwe ngendlela yayo emsulwa, kepha isisu saphendula kahle - akunamphumela emibi" .
U-Alena, oneminyaka engama-35, u-Ufa: "Nginesifo esingama-tillillitis esingamahlalakhona, ngakho-ke ngiphuza i-Amoxicillin. Noma kunjalo, anginankinga nesisu noma amathumbu ami. Angibonanga eminye imiphumela emibi. Futhi intengo iyamukeleka, kubalulekile."