I-Telmista 80 yi-ejenti elwa nama-antihypertensive enomphumela we-diuretic okhonjiwe, isetshenziselwa ekwelapheni nasekuvimbeleni i-pathologies yenhliziyo.
Igama Lezwe elingafanele
I-Telmisartan - I-Telmisartan.
I-Telmista 80 - i-ejenti ye-antihypertensive enomphumela we-diuretic.
I-ATX
C09CA07.
Khipha amafomu nokwakheka
Ithebula. Ngokusekelwe kokuqukethwe kwenani lezinto ezisebenzayo, amaphilisi angama-20 mg, ama-40 mg kanye nama-80 mg ayatholakala.
Into esemqoka yokusebenza kweTelmista yi-telmisartan. Izingxenye ezengeziwe: i-magnesium stearate, i-meglumine, i-lactose monohydrate, i-sodium hydroxide, hydrochlorothiazide (1 ithebhulethi iqukethe u-12,5 mg).
Isenzo se-Pharmacological
Izici zesidakamizwa zincike ekuxhumaneni kwe-telmisartan okuhlangene ne-hydrochlorothiazide, okuyi-diuretic. Umuthi uluhlobo olukhethiweyo oluchasisa isenzo olusebenzisa isenzo se-angiotensin ii. Ingxenye esebenzayo yesidakamizwa inobudlelwano obude ne-AT1 receptor.
Umuthi unciphisa inani le-aldosterone ku-plasma yegazi.
Umuthi unciphisa inani le-aldosterone ku-plasma yegazi. Awukho umphumela wokuvimba eziteshini nase-ion nasezonweni. Umphumela wokuvinjwa kwento ye-kininase II, enomphumela ophansi we-bradykinin, nawo awukho.
Ngomthamo we-80 mg, umuthi uvimbela ngokuphelele imiphumela ye-hypertgency ye-angiotensin II. Umphumela we-antihypertensive wenzeka ngemuva kwamahora ama-3 kusukela ngesikhathi sokungenisa. Uma umuntu kutholakala ukuthi une-arterial hypertension, umuthi usiza ukwehlisa umfutho wegazi we-systolic ngaphandle kokuthinta imvamisa yokushaywa kwenhliziyo.
Ngokuyeka okungazelelwe kwemithi, akunasifo sokuhoxa, izinkomba zokucindezela kancane kancane zibuyela kokujwayelekile.
I-Pharmacokinetics
Lapho zisemzimbeni, izingxenye zomuthi zidonswa yi-membrane ye-mucous yethambo lesisu. I-bioavailability ye-telmisartan ingama-50%. Umuthi osebenzayo usebenza phakathi nosuku, umphumela ophikisiwe uphikelela amahora angama-48.
Lapho zisemzimbeni, izingxenye zomuthi zidonswa yi-membrane ye-mucous yethambo lesisu.
Ngemuva kwamahora ambalwa kusetshenziswe umuthi, inani lempahla esemqoka epulazini yegazi liyakhwezwa, kungakhathalekile ukuthi laliphuthwe ngaphambi noma ngesikhathi sokudla. Umehluko ekuqoqweni kwezakhi eziseplasma kungenxa yobulili besiguli. Kwabesifazane, le nkomba izoba ngaphezulu.
Izinkomba zokusetshenziswa
Unikezwe:
- phambi kwe-hypertension ebalulekile;
- ekwelashweni kwesifo sikashukela sohlobo 2, lapho kuthinteka izitho zangaphakathi;
- njenge-prophylaxis yokufa phambi kwezifo zohlelo lwezinhliziyo ezigulini ezineminyaka engaphezu kwengama-50.
Ukulawulwa kwe-prophylactic, isidakamizwa sisetshenziswa ezimweni lapho isiguli sinomlando wezifo kanye nezinqubo ze-pathological ezifana nesifo sohlangothi, ukuphambuka emsebenzini wethambo lemithambo yegazi elibangelwa ukuphazamiseka kwegazi noma ukuvela kwesifo sikashukela i-mellitus. Ukunikezwa kwesikhathi lesi sidakamizwa kunciphisa ingozi yokuhlaselwa yisifo senhliziyo nokushaywa unhlangothi.
Ukulawulwa kwe-prophylactic, umuthi usetshenziselwa isifo sohlangothi.
Contraindication
Kuyenqatshelwa ukusebenzisa uma isiguli sinokungabekezeleleki kwezitho ezithile zomuthi. Okunye ukwephulwa:
- ukukhulelwa
- inkathi yokuhlanza;
- Izifo ze-biliary treak ezithambisayo;
- isiguli singabekezeleli izinto ezinjenge-lactose ne-fructose.
Umkhawulo weminyaka wokuthatha umuthi ubudala beminyaka isiguli esingaphansi kweminyaka engu-18.
Ngokunakekela
Kunokuphikisana okuningana kokusetshenziswa kwomuthi, lapho ukuphathwa kwawo kungenzeka kuphela ezimweni lapho kungenzeki khona ukufeza okuhle ngokusetshenziswa kwamanye amadivaysi ezokwelapha. Ngokuqapha, umuthi ubekelwe iziguli phambi kwale mibandela elandelayo:
- i-stenosis yohlobo lwe-arhente yohlobo lwama-artery adlula ezinso;
- i-arterial stenosis lapho kukhona izinso eyodwa kuphela;
- ukwehla kwegazi elijikelezayo;
- ukutholakala kwe-hyponatremia;
- ukuba khona kwe-hyperkalemia;
- ukuhlinzwa kokufakwa kwezinso;
- ukusolwa kwezinso okusolisayo;
- iziguli ezinenkinga yokusebenza kwesibindi;
- i-cardiomyopathy evimbayo, uhlobo lwe-hypertrophic.
Ungayithatha kanjani iTelmista 80?
Umuthi wenzelwe ukuphathwa ngomlomo, ukusetshenziswa kwenziwa kanye ngosuku, akukho okunamathiselwe ekudleni kokudla.
Ukuze uthole ukwelashwa kwe-hypertension ebalulekile kubantu abadala, umuthi ubekwa kumthamo wethebhulethi eyi-1 (ngenani lezinto ezisebenzayo elingama-40 mg). Inani lomuthi lingancishiselwa kuma-20 mg ngosuku. Uma isikhathi eside kungekho okunamandla okuthatha umuthi, ngokuya ngesinqumo sikadokotela oholayo, umthamo uyakhuphuka ube ngu-80 mg.
Njengolunye uhlobo, umuthi unqunywe ngokuhambisana nama-diuretics. Le nhlanganisela ikuvumela ukuthi uzuze umphumela obizwa kakhulu we-antihypertensive. Ukwanda komthamo kungenzeka kuphela uma kungekho zinguquko ezinhle kumaviki angama-4-8, ngoba umuthi unomphumela wokuqina.
Umuthi wenzelwe ukuphathwa ngomlomo, ukusetshenziswa kwenziwa kanye ngosuku.
Njenge-prophylactic yabantu abavela eminyakeni engama-50 ubudala abanezifo ezifanele ngethoni yenhliziyo, umthamo wansuku zonke yi-1 ithebhulethi kanye ngosuku. Ekuqaleni kokwelashwa, kungadingeka eminye imishanguzo yokulungisa izinkomba zokucindezela kwegazi.
Ukuthatha umuthi wesifo sikashukela
Umuthi kubantu abanesifo sikashukela ungavusa ukuthuthuka kwe-hypoglycemia, ngakho-ke, nalesi sidakamizwa, ukuqapha okuqhubekayo kwamazinga we-glucose kuyadingeka.
Uma kunesidingo, kulungiswa umthamo walokhu namalungiselelo e-insulin.
Imiphumela emibi
Amathuba wezimpawu ezimbi aphansi, inqobo nje uma umuthi uphuzwa ngokufanele, umthamo okhonjiswe udokotela oholayo, kanye nesiguli asinakho ukwephula lo muthi.
Amapheshana wesisu
Imiphumela emibi efana nobuhlungu esiswini, ukuphazamiseka kwesisu ngesimo sohudo, ukuthuthukiswa kwe-dyspepsia, ukuqhakaza njalo kanye nokuhlaselana, kanye nokuhlaselwa kwenhliziyo kuhlasela kakhulu. Kuyivelakancane kakhulu, kepha ukubukeka kwezimpawu ezinjengokoma emgodini womlomo, ukungakhululeki esiswini, nokuhlanekezela ukunambitheka akuhlanganisiwe.
Imiphumela emibi efana nobuhlungu esiswini akuvamile ukwenzeka.
Izitho zeHematopoietic
Ukuthuthukiswa kwe-anemia. Imiphumela emibi engafani ne-thrombocytopenia ne-eosinophilia. Umuthi ungavusa ukwanda kwenani le-uric acid.
Isistimu yezinzwa ephakathi
Akuvamile - izimo zokwehluleka. Ukuvela kokuzwa okuxakile kwesiguli ngokumelene nesizinda sokusebenzisa iTelmista akunqunyelwe.
Kusuka ohlelweni lomchamo
Kuyaqabukela - ukuthuthukiswa kwe-nephritis ye-interstitial, ukwehluleka kwezinso. Ukujoyina ukutheleleka ngokuthuthukiswa kwe-cystitis akubekiwe.
Kusuka ohlelweni lokuphefumula
Ukubonakala kokufushane kokuphefumula nokukhwehlela komile. Ezimweni ezingavamile kakhulu, ukuthuthukiswa kwesifo se-pulmonary interstitial.
Uhlelo lokuphefumula lungadala ukukhwehlela okuomile.
Kusuka ohlelweni lwezitho zofuzo
Izinkinga ezilandelayo azivamile ukwenzeka - ukungasebenzi kahle kwezinso, ukuthuthukiswa kokwehluleka kwe-renal acute.
Kusuka ohlelweni lwezinhliziyo
Ukuthuthukiswa kwe-bradycardia akuvamile ukubonwa, futhi kuyaqabukela, i-tachycardia. Umphumela omubi onjengokwehla kwezinkomba zokucindezela kwegazi awukhishwa.
Kusuka ezicutshini zemisipha
Ukuthuthukiswa kwe-sciatica (ukubukeka kobuhlungu esiswini), imisipha yemisipha, ubuhlungu ku-tendon.
Allergies
Imiphumela emibi esikhumbeni ukulunywa nokubomvu, i-urticaria, ukuthuthukiswa kwe-erythema ne-eczema. Kuyaqabukela, ukuphuza umuthi kuvusa ukukhula kwe-anaphylactic shock.
Kuyaqabukela, ukuphuza umuthi kuvusa ukukhula kwe-anaphylactic shock.
Imiyalo ekhethekile
Umuthi awuvamile ukunqunyelwa ezigulini ezingomjaho we-Negroid, ngoba kuleli cala ukusebenza komuthi kuphansi kakhulu. Lokhu kuchazwa yisimo sobuhlanga emsebenzini onciphile wento ye-renin. Umuthi ungakhuphula ithoni ye-vascular ezinso futhi uholele ekwandeni kwe-cholesterol uma isetshenziswa ihlanganiswe ne-diuretics.
Ukuhambisana notshwala
Ukuphuza utshwala neziphuzo eziqukethe utshwala kwenqatshelwe ngokuphelele.
Umthelela ekhonweni lokulawula izindlela
Akunemikhawulo ekushayeleni imoto nasekusebenzeni ngezinqubo eziyinkimbinkimbi. Kepha kuyadingeka ukuthi unake iqiniso lokuthi ngemuva kwesizinda sokusetshenziswa kwalesi sidakamizwa, ubungozi bokuqhamuka nezimpawu ezinjengokuhlasela kwesiyezi abukhishwa.
Akunemikhawulo ekushayeleni imoto nasekusebenzeni ngezinqubo eziyinkimbinkimbi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuze uvikele imiphumela emibi engaba khona kumntwana osanda kuzalwa, iTelmista ayivunyelwe ngesikhathi sokuncelisa ibele. Uma ukusetshenziswa kwalo muthi kudingekile, ukunqunywa kufanele kukhanselwe okwesikhashana. Ukukhulelwa kuwukuphikisana ngokuphelele nokuphuza umuthi.
Ukuqokwa kukaTelmist wezingane ezingama-80
Izifundo zemitholampilo maqondana nokuphatha umuthi ezigulini ezingaphansi kweminyaka engu-18 azenziwanga. Njengoba kunikezwe ubungozi bezinkinga ezingenzeka, izingane azinqunyelwe.
Sebenzisa ebudaleni
Akukho kulungiswa kwamthamo okudingekayo.
Isicelo sokusebenza kokulimala kwezinso
Akuvamile ukubekelwa iziguli ezine-renal dysfunction. Esimweni esinjalo, kuyadingeka ukusungula ukulawula ukugcotshwa kwe-potassium egazini nezinto ze-creatine.
Izakhi ezisebenzayo zidlulwa nge-bile, futhi lokhu, kuzodala umthwalo owengeziwe wesibindi kanye nokwanda kwezifo.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukusetshenziswa kwomuthi okwenziwa iziguli ezinokuhlonza okufana ne-cholestasis, izifo ezivimbayo zepheji le-biliary noma ngokwehluleka kwe-renal kwenqatshelwe ngokuphelele. Izakhi ezisebenzayo zidlulwa nge-bile, futhi lokhu, kuzodala umthwalo owengeziwe wesibindi kanye nokwanda kwezifo.
Kuvunyelwe ukuthatha umuthi kuphela uma isiguli sinamazinga aphansi futhi alinganiselayo wesifo sezinso. Kodwa umthamo ezimweni ezinjalo kufanele ube omncane, futhi umuthi kufanele uthathwe kuphela ngaphansi kokuqokwa udokotela.
Ukweqisa
Amacala okweqa ngokweqile awatholakali kakhulu. Izimpawu ezinokwenzeka zezimo eziba zimbi kakhulu ezenzeka ngokusetshenziswa ngokweqile komuthi ukuthuthukiswa kwe-tachycardia ne-bradycardia, hypotension.
Ukwelapha uma kwenzeka ukwanda kuba yimpawu. I-Hemodialysis ayisetshenziswanga ngenxa yokungakwazi ukususa izakhi zomuthi egazini.
Ukuxhumana nezinye izidakamizwa
Ukusetshenziswa kanyekanye nezidakamizwa zeqembu elifanayo kungakhuphula izinga lokwelashwa.
Ukusetshenziswa kanyekanye kwalo muthi ngezidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala: i-Ibuprofen, Simvastatin, Paracetamol, Glibenclamide nezinye izidakamizwa eziqukethe i-acetylsalicylic acid akuvunyelwe. Le nhlanganisela yezidakamizwa ingavusa ukuthuthuka kokwehluleka kwezinso ikakhulukazi kwiziguli ezinomzimba otholakele.
Ukusetshenziswa kanyekanye nezidakamizwa zeqembu elifanayo kungakhuphula izinga lokwelashwa.
Uma i-Telmist nemithi eqenjini le-antidiabetes isetshenziswa ngasikhathi sinye, ukulungiswa komthamo ngamunye wazo zonke izidakamizwa kuzodingeka.
Ama-Analog
Amalungiselelo anombono ofanayo wesenzo: I-Prirator, iMikardis, iTanidol, iTelzap.
Imibandela yekhefu lekhemisi
Kudingeka incwadi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Intengo yeTelmista 80
Kusuka kuma-ruble angama-320.
Izimo zokugcina zomuthi
Amazinga okushisa afika ku-25 ° С.
Umuthi unikezwa ngomuthi kuphela.
Isikhathi sokuphelelwa yisikhathi
Akudluli iminyaka emithathu.
Umkhiqizi
I-Krka, dd UNovo Mesto, eSlovenia
Ukubuyekezwa ku-Telmista 80
Imibono yeziguli nodokotela mayelana nomuthi ezimeni eziningi iyakhayo. Ithuluzi, uma lisetshenziswe kahle, kuyaqabukela kukhubaze ukukhula kwezimpawu eziseceleni. Umuthi ubuye wazibonakalisa njenge-prophylactic, unciphisa ubungozi bokuqala ngokungazelele kokuhlaselwa yinhliziyo nemivimbo kubantu abaneminyaka engama-55 ubudala.
Odokotela
UCyril, 51, ongudokotela wezifo zenhliziyo: "Okuwukuphela kwesimo esididayo seTelmista 80 ngumphumela wokuphindaphindeka, ngenkathi iziguli eziningi zifuna ukudambisa isimo sazo ngaso leso sikhathi. Nginikeza lo muthi kubantu asebekhulile abanomlando wokuhlaselwa yinhliziyo. Ungakusindisa ezingxenyeni eziningi futhi yehlisa izingozi zokushona kwabantu, njengoba kufakazelwa iminyaka eminingi yokubonwa. "
UMarina, oneminyaka engama-41 ubudala, udokotela wezokwelapha: “I-Telmista 80 iyakwazi ukuphatha kahle amazinga okuqala omfutho wegazi, futhi ngokwelapha okuhlanganisiwe kuyaphumelela ekwelapheni umfutho wegazi ophakeme we-degree 2. Ngokusebenzisa umuthi njalo, umphumela omuhle utholakala ngemuva kwamaviki angu-1-2, futhi uphawu olunjalo olungajabulisi njengolwaphakade Ukucindezela kokudlula kwengcindezi. Izehlakalo ezimbi zivamile kakhulu. "
Iziguli
UMaxim, oneminyaka engama-45, u-Astana: "Udokotela ubeke i-Telmist ukuthi ilashelwe isigaba sokuqala se-hypertension. Ngaphambi kwalokho ngazama izinto eziningi, kepha ezinye izidakamizwa zabangela imiphumela emibi noma azange zisize ngalutho. Kwakungekho zinkinga ngalo muthi ngemuva kwamasonto amabili kuqalile ukwelashwa. ingcindezi ibuyele kwesejwayelekile futhi yagcinwa ezingeni elifanayo, ngaphandle kokuxhuma okungathandeki. "
UKsenia, oneminyaka engama-55, uBerdyansk: "Uqale ukuthatha iTelmist ngemuva kokuqala kokuya esikhathini, ngoba ingcindezi ihlukunyezwe ngokuphelele. Umuthi usizile ukwenza izinkomba zijwayelekile. Noma ngabe ukweqa kwenzeka, akubalulekile futhi akulethi ukukhathazeka okukhulu."
U-Andrei, oneminyaka engu-35, eMoscow: "Udokotela uqoke ubaba weTelmist 80, wayeneminyaka engama-60, futhi wayesenesifo senhliziyo. Uma kucatshangelwa ukuthi umfutho wakhe wegazi uhlala ukhuphuka, kungenzeka ukuthi kungenzeka ukuthi isifo senhliziyo siphinde senzeke. Kwathatha cishe inyanga, ukuze umuthi uqale ukusebenza, kepha ubaba uwuthandile umphumela wokuwuthatha, ingcindezi ibuyele kwesejwayelekile. "
