I-AGAPURIN - IMIYALO ESETSHENZISWAYO, INTENGO, UKUBUYEKEZWA KANYE NAMA-ANALOGUES

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I-Agapurin CP ithuthukisa ukusebenza kohlelo lokujikeleza kwegazi futhi iqinise izindonga zemithambo yobuchopho.

Ukuze ugweme ukubanjwa ikhanda nobuhlungu bekhanda, kunconyelwa ukuthi kuhlolwe umuntu ngaphambi kokuqala ukusetshenziswa komuthi.

Igama Lezwe elingafanele

I-Pentoxifylline - igama lesakhi esisebenzayo somuthi.

I-Agapurin CP ithuthukisa ukusebenza kohlelo lokujikeleza kwegazi futhi iqinise izindonga zemithambo yobuchopho.

I-ATX

I-C04AD03 - ikhodi yokuhlukaniswa kwamakhemikhali okwelapha nokwelapha.

Khipha amafomu nokwakheka

Umuthi uyatholakala ngefomu lethebhulethi nangesixazululo somjovo we-intravenous. Ngokuya kobunzima benkambiso ye-pathological, udokotela ukhetha ifomu elilodwa noma elinye lomthamo.

Isixazululo

Umuthi uyatholakala kuma-ampoules ama-5 ama-pcs. emaphaketheni. I-1 ml yesisombululo iqukethe u-20 mg wento esebenzayo.

Uhlobo olungekho

Amacwecwe asemabhodleleni engilazi ama-60 ama-pcs. lilinye. Kepha kumakhemisi aseRussia, ungathenga kuphela umuthi wesenzo eside (ukubuyisela). Ukuqanjwa kwethebhulethi eyi-1 kufaka phakathi i-400 mg ye-pentoxifylline. Amathebulethi angama-20 ayatholakala ekuhlanganisweni kwesibili.

I-Agapurin ine-antispasmodic effect, ithuthukisa i-arterial or venous microcirculation, ngaphandle kokukhulisa isilinganiso senhliziyo.

Amacwecwe asemabhodleleni engilazi ama-60 ama-pcs. lilinye.

Umuthi uyatholakala kuma-ampoules ama-5 ama-pcs. emaphaketheni. I-1 ml yesisombululo iqukethe u-20 mg wento esebenzayo.

Isenzo se-Pharmacological

Umuthi unomphumela we-antispasmodic, ngcono i-arterial or venous microcirculation, ngaphandle kokukhulisa ukushaya kwenhliziyo.

Isakhi esisebenzayo somuthi siphuzisa imithambo yenhliziyo namaphaphu.

Ngaphezu kwalokho, ithuluzi lisusa ubuhlungu obukhulu emaphethelweni aphansi nge-atherosulinosis.

I-Pharmacokinetics

Lapho sikhishwa ngomlomo, umuthi udonswa usuka endaweni yokugaya ungene ekujikelezweni kwe-systemic.

Imikhiqizo yokuwohloka yento esebenzayo idonswa ikakhulukazi yizinso ezinomchamo, kanye nenani elincane elinama-feces.

Ekwehlulekeni kwe-renal okungamahlalakhona, kunenqubo eyehlisiwe yokunciphisa izidumbu.

Trental | imiyalo esetshenzisiwe

Ukubuyekezwa kukadokotela mayelana neTrental yezidakamizwa: izinkomba, ukusetshenziswa, imiphumela emibi, i-contraindication

Izinkomba zokusetshenziswa

Ithuluzi likhonjiswa:

isifo sokuqina kwemithambo yegazi emithanjeni yemilenze;
ukuthuthukiswa kwenqubo yokuvuvukala yemisuka ehlukahlukene;
ukwephulwa kwe-microcirculation ezitsheni zobuchopho;
Isifo sikaRaynaud's (isifo sokwehla kwamathambo);
ukwephula ukuhanjiswa kwegazi kwezicubu, okuholela ekushintsheni kwethonya esikhunjeni (i-gangrene, i-frostbite yobunzima obuhlukahlukene);
i-pathology yokunikezwa kwegazi ku-choroid yeso;
ukulahleka kokuzwa (ukungasebenzi kwendlebe ephakathi ngemuva kokuphazamiseka kwemithambo yegazi);
i-angiopathy yesifo sikashukela (ukulimala kwemikhumbi emincane).

Contraindication

Umuthi awukwazi ukuthathwa emacaleni amaningi anjalo:

i-angina engazinzile ngemuva kokuhlaselwa yisifo senhliziyo;
umunyu wecorrhea obangelwa yisifo sohlangothi;
ukulimala emuva
i-arteriosulinosis obliterans (ukwakheka kwama-atherosulinotic plaque, okuholela ekunciphiseni kwe-lumen yemithambo yegazi);
i-porphyria (ukwephulwa kwe-pigment metabolism);
uma kwenzeka kutholakala ukungabekezelelani kwe-pentoxifylline yomuntu ngamunye.

I-Agapurin imiselwe ukulahleka kwezindlebe (ukuqina kwendlebe okuphakathi emuva ngemuva kokuphazamiseka kwemithambo yegazi).

Ukwehla kobuchopho obangelwa yisifo sohlangothi kuwukuphikisana nokusetshenziswa komuthi.

Umuthi awukwazi ukuthathwa ngomonakalo kwi-retina.

Kufanele wenqabe ukwelapha izifo zemithambo nge-Agapurin uma isiguli sinomfutho wegazi ophansi.

Ngokunakekela

Kufanele wenqabe ukwelapha izifo zemithambo yegazi nge-Agapurin uma isiguli sinomfutho ophansi wegazi kanye nokusebenza kahle kwesibindi, kanye nokuthambekela kokuya esikhathini (hemorrhages).

Ungayithatha kanjani i-Agapurin

Uma kukhulunywa ngokufakwa, umthamo omkhulu wansuku zonke wezinto ezisebenzayo ungaphezu kwe-0.3 g.

Ngomjovo we-intramuscular, i-1 ampoule (100 mg ye-pentoxifylline) isetshenziswa kabili ngosuku.

Umuthi osefomini yethebhulethi uthathwa ngomlomo ngemuva kokudla. Kubalulekile ukuphuza ithebhulethi nengilazi yamanzi.

Ngoshukela

Kunconywa ukwelashwa okuxhaswa, okubandakanya ukusetshenziswa kwe-0.1 g yesithako esisebenzayo kathathu ngosuku izinyanga eziningana.

Umuthi osefomini yethebhulethi uthathwa ngomlomo ngemuva kokudla, kubalulekile ukuphuza ithebhulethi nengilazi yamanzi.

Kungenzeka yini ukuthatha isigamu sethebhulethi

Imiyalo ithi umuthi awukwazi ukuhlafunwa, ngakho-ke ukuthatha isigamu sethebhulethi kuyaphikiswa.

Imiphumela emibi ye-Agapurin

Umuthi ubangela ukuguquguquka okukhulu komzimba, okudinga ukucwaningisisa kahle kwemiyalo yokusebenzisa umuthi.

Engxenyeni yesitho sombono

Kwezinye izikhathi kunokuncipha kwe-acuity ebonakalayo, imibuthano ngaphansi kwamehlo ingavela.

Amapheshana wesisu

Ukomelela emgodini womlomo kuyaqabukela kwenzeka, futhi izimpawu ze-hepatitis ziya zanda. Iziguli zivame ukulahlekelwa yinhliziyo.

Izitho zeHematopoietic

Ezimweni ezingavamile, izinga lamapuleti egazini liyancipha. Ukuchithwa kolwelwesi lwe-mucous lomgudu wokugaya ukudla kuyabonakala.

Isistimu yezinzwa ephakathi

Iziguli zakha isimo sokukhathazeka. Ubuhlungu bekhanda kwesinye isikhathi buyaphazamisa.

Ngemuva kokuthatha i-Agapurin, kwesinye isikhathi isiguli siphazanyiswa ikhanda.

Ukusuka ohlelweni lwezinhliziyo, amacala okubonakala kwe-arrhythmia ne-tachycardia akuvamile.

Ngemuva kokuthatha umuthi, isifiso sokudla sivame ukwanda.

Nge-hypersensitivity kwento esebenzayo, kuvela ukuqhuma esikhunjeni, okungahle kuhambisane nokulunywa.

Ngasohlangothini lwesitho sombono, imibuthano ngaphansi kwamehlo ingavela.

Kusuka ohlelweni lokuphefumula

I-Hypertonicity yemisipha ebushelelezi yohlelo lokuphefumula iyabonakala.

Kusuka ohlelweni lwezinhliziyo

Ama-Arrhythmias ne-tachycardia ajwayelekile.

Allergies

Nge-hypersensitivity kwento esebenzayo, kuvela ukuqhuma esikhunjeni, okungahle kuhambisane nokulunywa.

Umthelela ekhonweni lokulawula izindlela

Ngokuqapha, thatha lo muthi kubantu abasebenza imisebenzi yobungcweti ehlotshaniswa nokunakwa okukhulu.

Imiyalo ekhethekile

Kubalulekile ukucubungula izici eziningana ukuze uzuze amandla amahle ezimpawu zomtholampilo.

Uma isiguli sineminyaka engaphezu kwengu-65 ubudala, khona-ke ukukhethwa komthamo kwenziwa ngokuqinile ngasese.

Sebenzisa ebudaleni

Uma isiguli sineminyaka engaphezu kwengu-65 ubudala, khona-ke ukukhethwa komthamo kwenziwa ngokuqinile ngasese.

Ukunquma u-Agapurin ezinganeni

Abukho ubufakazi bokusetshenziswa okuphephile kwalesi sidakamizwa yiziguli ezingakafiki iminyaka eyi-18.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Ukusetshenziswa kwe-Agapurin kunoma iyiphi i-trimester nangesikhathi sokuqunjelwa kuyaphulwa.

Isicelo sokusebenza kokulimala kwezinso

Ukusetshenziswa kwemithamo emincane yento esebenzayo kuvunyelwe.

Sebenzisa umsebenzi wesibindi okhubazekile

Umuthi ubekwa ngokuqapha ekuboneni ukwehluleka kwesibindi.

Ukusetshenziswa kwe-Agapurin ngesikhathi sokuncelisa ibele kutshelwe.

Ukweqisa kwe-Agapurin kungadala ukulahleka kwengqondo.

Nge-overdose yesidakamizwa, ukozela kwenzeka.

Umuthi ubekwa ngokuqapha ekuboneni ukwehluleka kwesibindi.

Ukweqisa kwe-Agapurin

Ukuvela kwezibonakaliso zangaphandle ezilandelayo kungenzeka:

ubomvu besikhumba;
ukulahleka kwengqondo;
ukushisa ngemuva ngemuva kokushisa komzimba okukhuphukile;
ukozela

Ukwelashwa okubonakalayo kuyadingeka ukulungisa isimo.

Ukuxhumana nezinye izidakamizwa

Kubalulekile ukucubungula okulandelayo:

Into esebenzayo i-Agapurin ithuthukisa umphumela wokwelapha wama-antibhiliya nezidakamizwa ze-hypoglycemic zomlomo.
I-Cimetidine inyusa ukugcwala kwe-pentoxifylline ku-plasma yegazi, okwandisa ubungozi bemiphumela emibi.
Kuvunyelwe ukusebenzisa izithasiselo zokudla ezifaka isandla ekwenzeni ngcono uhlelo lwenhliziyo.

Ukuhambisana notshwala

Ukusetshenziswa kanyekanye kweziphuzo eziqukethe utshwala kudala ukwehla kokusebenza kwe-Agapurin.

Njengokubambela i-Agapurin, iVasonite iyasetshenziswa.

I-Trental iyi-analogue ephumelelayo ye-Agapurin.

Ama-Analog

I-Trental ne-Wasonite azikho izifanekiselo ezingekho ngaphansi kwe-Agapurin.

Imibandela yekhefu lekhemisi

Umkhiqizo usatshalaliswa ngugqirha.

Ngingakwazi ukuthenga ngaphandle kadokotela

Kunezimo ezivame ukwenzeka lapho umuthi uthengwa ngaphandle kadokotela.

Intengo Agapurin

Izindleko zamathebulethi ziyehluka kusuka kuma-ruble angama-250 kuya kwangama-300.

Izimo zokugcina zomuthi

Umuthi kufanele ugcinwe emazingeni okushisa asekamelweni.

I-Agapurin itholakala ngomuthi kadokotela.

Izindleko zamathebulethi ziyehluka kusuka kuma-ruble angama-250 kuya kwangama-300.

Umuthi lo wenziwa ngabakwaZentiva a.s (Slovak Republic).

Isikhathi sokuphelelwa yisikhathi

Amacwecwe agcina izakhiwo zawo zokwelapha iminyaka engu-5 kusukela ngosuku lokukhiqizwa, kanye nesisombululo somjovo - iminyaka emi-3.

Umkhiqizi

Umuthi lo wenziwa ngabakwaZentiva a.s (Slovak Republic).

Ukubuyekezwa mayelana ne-Agapurin

UMikhail, oneminyaka engama-35, eMoscow

Ngisebenzisa umuthi ukusheshisa ukwakhiwa kwemisipha. Ngithatha i-Riboxinum ngasikhathi sinye. Kepha ngincoma ukuthi uqale uthintane nodokotela wakho maqondana nokusetshenziswa kwe-Agapurin ekwakheni umzimba neminye imidlalo.

U-Ana, oneminyaka engama-55, eSt

Ngisebenzisa umuthi ngokuhlangana nomuthi we-herbal uLeuzea ukukhulisa ukusebenza kwengqondo. Akunamiphumela emibi yenzekile. Ngenelisekile ngomphumela wokwelashwa.

U-Olga, oneminyaka engama-43, u-Omsk

Wathatha i-Agapurin ukuthuthukisa ukwenziwa kwe-microcirculation ebuchosheni. Ubhekene nesiyezi esinzima, okwabangela ukwenqatshwa kwalo muthi. Manje ngiyahlolwa.

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