Ukuhlaziya

Ukulinganiswa kwesilinganiso se-erythrocyte sedimentation kanye nenani le-cholesterol ku-plasma kusivumela ukuthi sisole ukuba khona kwezifo ngendlela esifike ngesikhathi, sikhombe imbangela yazo, bese siqala ukwelashwa okufika ngesikhathi. Izinga le-ESR kungenye yezindlela ezibaluleke kakhulu lapho uchwepheshe ahlola isimo sezempilo yabantu.

I-Atherossteosis yisifo esithinta umzimba wonke. Kubonakala ngokufakwa kwezixakaxaka ezikhethekile ze-lipid ezindongeni zangaphakathi zemithambo yegazi, ngesimo esibizwa ngokuthi yi-cholesterol plaque, esinciphisa ukukhanyisa komkhumbi futhi kuphazamise ukunikezwa kwegazi kwizitho. Emhlabeni jikelele, izifo zenhliziyo zithatha indawo yokuqala ekufeni kwabantu, futhi i-atherosclerosis iyinto ehamba phambili enomthelela ekwakhekeni kwezifo zenhliziyo nezemithambo.Ungayihlola kanjani imithambo yegazi ye-atherossteosis?

I-cholesterol yegazi ingenye yezinkomba ezibaluleke kakhulu, ikhombisa ubungozi bokuqalwa kwe-atherosclerosis yemithambo yegazi, ukwakheka kwamachaphaza cholesterol ezindongeni zawo. Ukwakheka kwento efana namafutha ngotshwala be-lipophilic, kuqukethwe kulwelwesi lwesitho somzimba. Ngemuva kweminyaka yobudala engama-40, umuntu ngamunye uyanconywa ukuba enze ucwaningo futhi athathe ukuhlolwa kwegazi okujwayelekile emtholampilo nakwa-biochemical.

I-cholesterol ephakanyisiwe ibika ukwephulwa kwe-lipid metabolism. Lokhu kungaholela emiphumeleni emibi ngesimo se-atherossteosis, i-thrombosis, isifo senhliziyo, coralary infarction kanye nesifo sohlangothi. Uma i-pathology yangaphambili ibivame ukutholakala kubantu asebekhulile, esikhathini sanamuhla ngisho nentsha isengozini.

I-cholesterol yinto efana namafutha ethi, ngokweqile, ibangele ukwakheka kwama-atherosulinotic plaque kanye nesifo esiyingozi se-atherossteosis. Le ngxenye ihlukaniswa njenge-lipid, ikhiqizwa isibindi futhi ingangena emzimbeni ngokudla - amafutha ezilwane, inyama, amaprotheni.

Uma umfutho wegazi uvamile, lokhu kukhombisa impilo enhle. Ipharamitha elifanayo lihlola ukuthi kusebenza kahle kangakanani izicubu zenhliziyo nemithambo yegazi. Ukwehlisa noma ukukhulisa ingcindezi kukuvumela ukuthi ubone ukuba khona kwezifo ezahlukahlukene. Lapho kutholakala ukuthi unesifo sikashukela i-mellitus, kubalulekile ukubheka njalo isimo semithambo nasekhaya ukukala amapharamitha usebenzisa i-tonometer.

Ngomfutho wegazi, kuyisiko ukuqonda ingcindezi igazi elisebenza ngayo ezindongeni zangaphakathi zemithambo yegazi. Izinkomba zokucindezela zingabonakala ngamanani amabili. Owokuqala amandla okucindezela ngesikhathi sokuqothuka okukhulu kwemisipha yenhliziyo. Lona umfutho wegazi ophezulu, noma we-systolic. Okwesibili kungamandla okucindezela ngokuqabuleka okukhulu kwenhliziyo.

Ukwephulwa kwe-metabolism yamafutha ezigabeni zokuqala kungatholakala kuphela usebenzisa ukuhlolwa kwegazi kwe-biochemical. Ngeshwa, ukubonakala kwezikhalazo ze-subjential kuwusongo olukhulu lomzimba futhi kunenani elingelona iqiniso le-proology. I-Atherossteosis yisifo esivame kakhulu esihambisana nokuphazamiseka emzimbeni we-lipid emzimbeni.

Ngemuva kweminyaka engamashumi amane, amadoda kudingeka alawule amazinga e-cholesterol e-plasma. Imvamisa, izinga eliphakeme lalesi sakhi alizivezi nganoma iyiphi indlela, noma kunjalo, uma ungalawuli inqubo, izifo ze-vascular nezenhliziyo zingaba khona maduze nje, futhi kungahle kube nokuhlasela kwenhliziyo. Kufanele uqonde ukuthi yiziphi izinkomba ze-cholesterol yegazi okuyinto evamile kwabesilisa abaseminyakeni ethile, ukuthi benzeni ngezinga elikhulayo / lehla lezinto nokuthi yiziphi izindlela zokuthibela ezingathathwa.

Umfutho wegazi ungamandla athile lapho igazi licindezela khona odongeni lwemithambo yegazi. Kubalulekile ukukhumbula ukuthi igazi aligcini nje ukugeleza, kepha liqhutshwa ngenhloso ngosizo lwemisipha yenhliziyo, elandisa umphumela walo wokusebenza ezindongeni zemithambo. Ukugeleza kwegazi kuhambisana nokusebenza kwenhliziyo.

I-cholesterol yinto eyinkimbinkimbi enjengamafutha etholakala kulolwelwesi lwawo wonke amaseli aphilayo. Lesi sakhi sithatha ingxenye ebonakalayo ekwenziweni kwamahomoni e-steroid, sikhuthaza ukumuncwa kwe-calcium ngokushesha, silawula ukwakheka kuka-Vitamin D. Uma inani eliphelele le-cholesterol lingamayunithi ama-5, ingabe liyingozi? Leli nani lithathwa njengejwayelekile, alidluli okujwayelekile okunconyiwe.

I-cholesterol utshwala obunamafutha obukhiqizwa esibindini somuntu, izinso, amathumbu, nezindlala ze-adrenal. Ingxenye ibamba iqhaza ekwakheni ama-hormone e-steroid, ekwakhiweni kwe-bile, futhi inikeze amaseli omzimba ngezakhi zokudla okunempilo. Okuqukethwe yile nto kuthinta ngqo ukusebenza kobuchopho, uhlelo lwenhliziyo nethambo lesisu.

I-cholesterol yinto efana namafutha ebopha amaprotheni futhi iholele ekwakhekeni kwama-atherosclerotic plaque. Yizinto ezifakwa ngaphakathi emithanjeni yegazi ezothuthukisa ukukhula kwe-atherosclerosis ku-mellitus yesifo sikashukela. Into ingeyoyesigaba samafutha. Inani elincane - i-20%, lingena emzimbeni womuntu ngokudla komdalo wesilwane.

I-cholesterol, i-chole choleol, utshwala obunamafutha obukhiqizwa esibindini somuntu futhi obangela izinqubo eziningi emzimbeni. Iseli ngalinye "limboziwe" ungqimba lwe-cholesterol - into edlala indima yomlawuli wezinqubo ze-metabolic. Ingxenye enjengamafutha ibaluleke kakhulu enkambweni ejwayelekile yazo zonke izinqubo zamakhemikhali nezokudla emzimbeni womuntu.

Cishe ikota yabantu bomhlaba bakhuluphele. Bangaphezu kwezigidi eziyishumi abantu abafayo minyaka yonke ngenxa yezifo zenhliziyo. Cishe izigidi ezi-2 zeziguli zinesifo sikashukela. Futhi imbangela evamile yalezi zifo ukugcwala okwandayo kwe-cholesterol. Uma i-cholesterol ingu-17 mmol / L, kusho ukuthini lokhu? Inkomba enjalo izosho ukuthi isiguli "sidlula" inani lotshwala obunamafutha emzimbeni, ngenxa yokuthi ingozi yokufa kungazelelwe ngenxa yokuhlaselwa yisifo senhliziyo noma unhlangothi ikhuphuka kaningi.

I-cholesterol iyingxenye yezindonga zeseli zezicubu zazo zonke izinto eziphilayo. Lento ibhekene nokubanika ukuqina nokuqina kwesakhiwo. Ngaphandle kwe-cholesterol, amangqamuzana omzimba womuntu abengeke enze imisebenzi yawo eminingi. Esibindini, leli khompiyutha libandakanyeka ekuhlanganiseni nasekusebenzeni kwama-hormone e-steroid njenge-testosterone, estrogens, glucocorticoids.

Noma ngubani otholakala nesifo sikashukela uyazi ukuthi i-cholesterol ephezulu iyinkomba embi. Ukuqongelela ngokweqile kwama-lipid egazini kuholela ekuthuthukisweni kwezifo zenhliziyo, isifo sokuqina kwemithambo yegazi, isifo senhliziyo nokushaywa unhlangothi. Okwamanje, kunento efana ne-cholesterol enhle nembi.

I-cholesterol iyingxenye ebalulekile yamaseli nezicubu, yinto ebaluleke kakhulu empilweni. Uma izinkomba zayo ziqala ukwedlula okujwayelekile, kunengozi yokukhula okusebenzayo kwezifo zenhliziyo nezemithambo.I-cholesterol eyeqile iba yinkinga enkulu kwiziguli ezinesifo sikashukela i-mellitus, ikakhulukazi kwabesifazane ngesikhathi sokulungiswa kwe-hormonal kanye nokuya esikhathini.

I-Cholesterolemia isho inani eliphelele le-cholesterol esegazini lomuntu. Futhi, leli gama lingasho ukuphambuka kokujwayelekile, imvamisa babhekisela kwi-pathology. Kwesinye isikhathi igama elisho kuphela ubungozi besifo. Ukuze kwenzeke into efana ne-cholesterolemia, babeka ikhodi engu-E 78 ngokuya ngezigaba zomhlaba wonke kwezifo.

I-cholesterol ibonakala njengesibonakaliso esibalulekile se-biochemical yegazi, esibonisa ubungozi bokuqalwa kwe-atherosclerosis ebantwini. Lolu cwaningo lunconywa kubo bonke abantu abadala kanye njalo eminyakeni engama-2-3, nasezigulini ezisengozini kaningana ngonyaka. Iziguli ezinezifo ze-endocrine (ngokwesibonelo, isifo sikashukela), izifo zesibindi zemithi ehlukahlukene, ukungasebenzi kahle kwesibindi, i-pathologies yenhliziyo, njll. Zisengozini.