Imiyalo yokusebenzisa isisombululo se-glucose kuma-ampoules

Isixazululo sikashukela siwumthombo wama-carbohydrate angagaya kalula. Umuthi uyakwazi ukumboza ingxenye yezindleko zamandla futhi uthuthukise izinqubo ze-redox emzimbeni. Into esebenzayo yesidakamizwa ayikhutshwa yizinso futhi imunca ngokuphelele umzimba. Ngaphambi kokusebenzisa umuthi, kunconyelwa ukuthi ufunde isichasiso sakho bese uthintana nochwepheshe.

Ukwakheka nefomu lokukhululwa

Into esebenzayo yesidakamizwa yi-glucose monohydrate. Izithako ezingeziwe zifaka:

• amanzi omjovo;
• i-hydrochloric acid;
• i-sodium chloride.

Isixazululo sikhishwa ngesimo soketshezi olungenamibala, okhanyayo ophuzi. Ibekwe kuma-ampoules angama-5 ml. Kunama-ampoule ama-5 nesikhafu sokuwavula kwiphakethe lokulimaza.

Umuthi awukwazi ukusetshenziswa ngemuva kosuku lokuphelelwa yisikhathi, okuyiminyaka engu-3 ngokulondolozwa okufanele.

Izici ze-Pharmacological

Ingxenye esebenzayo ingena kuzo zonke izicubu nezitho zomzimba ngemigoqo yomlando. I-insulin ilawula ukuthuthwa kweseli. Ngokusho komzila we-pentose phosphate ne-hexose phosphate, lesi sidakamizwa siqhubeka nenqubo ye-biotransformation ngokwakhiwa kwe-glycerin, amino acid, i-nucleotides kanye nezinto ezihlanganisiwe ze-macroergic.

Ngesikhathi se-glycolysis ngokwakhiwa kwamandla ngendlela ye-ATP, ushukela wenzelwa amanzi kanye ne-carbon dioxide. Imikhiqizo eyi-Half-life iphuma ezinso nasemaphashini. IGlucose iphinda ibize izindleko zamandla. Ngaphansi kwethonya lazo, i-diuresis iyanda, umsebenzi wesibeletho womsipha wenhliziyo nokwenziwa kwesibindi uyathuthuka, ukugeleza kwamanzi kuye egazini kusuka ezicutshini kulawulwa, ukucindezelwa kwe-osmotic ye-intravascular kuyabhalwa ngokujwayelekile, futhi izinqubo ze-metabolic ziyasheshiswa.

Into esebenzayo ingumthombo wamandla nezakhi zomzimba.kudingekile ukuqinisekisa imisebenzi ebalulekile yomzimba. Esibindini, kusebenze ukufakwa kwe-glycogen, futhi futhi kuthuthukisa izinqubo ze-oxidation nokululama.

Izinkomba kanye ne-contraindication

Isichasiselo sikhombisa inhloso enkulu nemikhawulo yokuphuza umuthi. Isibonakaliso esiyinhloko sokusetshenziswa kwekhambi yi-hypoglycemia. Contraindication ifaka lezi zimo ezilandelayo:

• hypersensitivity kwisithako esisebenzayo;
• i-delirium yotshwala kanye nokuphelelwa ngamandla komzimba;
• i-anuria
• i-pulmonary edema nobuchopho;
• ukwehluleka okukhulu kwe-ventricular kwesokunxele;
• i-hemorrhage entanjeni yomgogodla yohlobo olungaphansi kwe-subarachnoid kanye ne-intracranial;
• isifo sikashukela mellitus;
• i-hyperosmolar coma;
• hyperlactacidemia;
• i-glucose-galactose malabsorption.

Nge-hyponatremia, ukwehluleka kwenhliziyo ukubola, kanye nokwehluleka kwezinso, umuthi kufanele usetshenziswe ngokuqapha.

Imiyalo yokusebenzisa

Umuthi uphathwa ngokuhlinzwa noma ngokudonsa ngesilinganiso esiphezulu samaconsi ayi-150 ngomzuzu. Umthamo wansuku zonke akufanele udlule ku-2000 ml. Ngokwe-metabolism ejwayelekile, umthamo owodwa kumdala ngu-300 ml. Ekukondleni kwabazali, izingane zenziwa kusuka ku-6 kuye ku-15 ml nge-1 kg yesisindo. Umuthi awuhloselwe ukusetshenziswa kwe-intramuscular noma subcutaneous.

Imiyalo yokusebenzisa i-glucose ikhombisa ukuthi ukuthola okugculisayo kwengxenye esebenzayo, kuyadingeka ukulawula inani layo umchamo nasegazini, kanye nokuthatha i-insulin. Ngaphansi kwezinqubo ezijwayelekile ze-metabolic, isilinganiso sokuphathwa kwekhambi kubantu abadala ngu-0.5 ml nge-1 kg ngehora, ezinganeni - 0,25 ml. Phakathi kwemiphumela emibi yile:

• venous thrombosis;
• i-phlebitis;
• ukuthukuthela kwe-vein;
• ubuhlungu endaweni yomjovo;
• i-acidosis;
• i-hyperglycemia;
• i-polyuria;
• i-hypophosphatemia;
• isicanucanu
• hypervolemia
• i-angioedema;
• imivimbo yesikhumba;
• umkhuhlane.

Umuthi unomphumela wokufaka ngenkathi usebenzisa isisombululo se-sodium chloride. I-glucose ngumenzeli onamandla oxidizing.ngakho-ke, akunconywa ukuba kuphathwe kwisirinji efanayo nemikhiqizo yegazi kanye ne-hexamethylenetetramine ngenxa ye-erythrocyte hemolysis ne-aggregation.

Umuthi uyakwazi ukwehlisa umsebenzi we-nystatin, i-streptomycin, i-adrenergic agonists kanye ne-analgesics. Ezimweni ze-Normoglycemic, ukuthola kahle ushukela, kwethulwa isisombululo kunconywa ukuthi kuhlanganiswe ne-insulin.

Analogs of izindlela

Umuthi unezinto ezizobambela. Umlingani waso owaziwa kakhulu yiGlucosteril. Lesi sidakamizwa sibekelwe ukondleka okuyingxenye kobuzali kanye nokuvuselelwa komzimba kabusha.

Into esebenzayo ye-Glucosteril ithuthukisa umsebenzi we-antitoxic wesibindi futhi ithuthukise inqubo yezinqubo zokubuyisa kanye ne-oxidation. Ukwelapha kunomthelela ekugcwaliseni ukushoda kwamanzi. Ukungena ezicutshini, isakhi esisebenzayo sifakwa phosphorylated futhi siguqulwa ku-glucose-6-phosphate. Ngenqubo yokugaya umzimba, kukhiqizwa inani elanele lamandla, elidingekayo ukuqinisekisa ukusebenza komzimba. Isisombululo se-Hypertonic sidambisa imithambo yegazi, sandisa i-diuresis kanye ne-myocardial contractility, sandisa umfutho wegazi osmotic.

Ukufakwa ngokushesha kwento esebenzayo, kubhalwe i-1 UNIT ye-insulin nge-4 ml yesidakamizwa. Lapho kuhlanganiswa neminye imithi, kunconyelwa ukubuka ukuhambisana. Ekukondleni kwabazali ebuntwaneni, ezinsukwini zokuqala zokwelashwa, i-6 ml yomuthi nge-1 kg yesisindo somzimba kufanele ihanjiswe. Ngaphansi kokuqondisa kukachwepheshe, umuthi usetshenziselwa i-anuria ne-oliguria.

Ukuzifaka esikhundleni se-glucose solution nezinye izidakamizwa akuvunyelwe. Ukubonisana nodokotela odingekayo kuyadingeka.

Ukubuyekezwa kweziguli