Umlenze uphuthuma, unyawo lwesifo sikashukela

Imvamisa kusifo sikashukela i-mellitus, ukuthuthukiswa kwezifo ezibangelwa ukubonwa kuyabonakala, imbangela yazo ukuphazamiseka komzimba okubangelwa yi-hyperglycemia. Ukwehluleka ukuhambisana nemiyalelo yezokwelashwa, kanye nesifo sikashukela esibuhlungu, kungakha izilonda, ikakhulukazi emilenzeni. Izilonda zesifo sikashukela noma ezinde kakhulu zivame kakhulu.

IGangrene ingukufa kwasendaweni (i-necrosis) yezicubu ezithweni eziphilayo. Kuyingozi ngoba kufaka igazi enobuthi be-cadaveric futhi kuholela ekwakhiweni kwezinkinga ezibulalayo ezivela kwizitho ezibalulekile: izinso, amaphaphu, isibindi nenhliziyo. I-gangrene kwisifo sikashukela ivame ukwenzeka uma kuvela isifo sikashukela sonyawo, futhi isiguli singakunaki ukwelashwa kwayo.