Ungayisebenzisa kanjani isidakamizwa i-Noliprel forte?

Isenzo somuthi sihloselwe ekwelashweni okuyinkimbinkimbi kwe-arterial hypertension, ukuhluleka kwenhliziyo. Umuthi ukhipha uketshezi oluningi emzimbeni, uvimbele i-vasoconstriction futhi uthuthukise isimo sohlelo lwethambo nenhliziyo. Ukuhlanganiswa okuhlanganisiwe kugwema i-hyperkalemia.

I-ATX

S09BA04.

Isenzo seNoliprel Forte sihlose ekwelashweni okuyinkimbinkimbi kokuqina komfutho we-arterial, ukuhluleka kwenhliziyo.

Khipha amafomu nokwakheka

Umuthi uyatholakala ngesimo samaphilisi amhlophe. Ithebhulethi ngayinye iqukethe izithako ezisebenzayo - i-perindopril tertbutylamine ne-indapamide ngenani le-4 mg + 1.25 mg.

Isenzo se-Pharmacological

Yehlisa umfutho wegazi kunoma yisiphi isikhundla somzimba.

I-Perindopril iyi-angiotensin eguqula i-enzyme inhibitor. Ingxenye ivimbela i-vasoconstriction, ibuyisela ukuqina kwemithambo yegazi. I-Indapamide yi-diuretic ebangela ukuchama kaningi futhi isuse i-sodium, magnesium, potassium emzimbeni. Ingxenye ithuthukisa umphumela we-vasodilating we-perindopril. Lapho uthatha umuthi, ingcindezi iyaqina kungakapheli inyanga. Ngemuva kokuyekiswa komuthi, akukho ukwehla kwengcindezi.

I-Pharmacokinetics

Imunca ngokushesha. Ukuqoqwa kwe-perindopril kufinyelela inani layo eliphezulu egazini ngemuva kwamahora we-3-4. Esibindi, ingxenye iguqulwa i-perindoprilat. Ingxenye yokuhlangana namaprotheni. Umzimba awuhlanganisi. Umuthi ukhishwa emchameni.

INoliprel Forte imiselwe ukukhuphuka okuqhubekayo nokuhlala isikhathi eside komfutho wegazi.

I-Indapamide imunca ngokuphelele emgudwini wokugaya ukudla. Ukuhlaziywa kwe-plasma ephezulu kutholakala ngemuva kwemizuzu engama-60. Isigamu sibopha amaprotheni e-plasma. Ayiqongeleli izicubu. Kukhishwe izinso namathumbu.

Izinkomba zokusetshenziswa

Umuthi ubekelwe ukukhuphuka okuqhubekayo nokuhlala isikhathi eside komfutho wegazi.

Contraindication

Ngaphambi kokusebenzisa umkhiqizo, kufanele uzijwayeze le mibiko elandelayo:

• ukuzwela kuzakhi;
• I-edema kaQuincke;
• ukwephulwa okukhulu kwesibindi nezinso;
• i-potassium yegazi ephansi;
• ukuhlanganiswa nezidakamizwa ezandisa isikhathi sokuphumula kwe-QT;
• ukukhulelwa
• ukuntuleka kwe-lactase.

Lapho ukuncelisa ibele, ukwelashwa akuvunyelwe.

Ungayithatha kanjani?

Umuthi kufanele uphuzwe isikhathi esingu-1 ngosuku ngethebhulethi eyi-1. Kungcono ukwenza ukwamukela ekuseni. Ebudaleni, ngokwehluleka kwezinso okubucayi kuya kobukhulu obulinganisile, akudingekile ukunciphisa umthamo.

I-edema kaQuincke iwukuphikisana nokuthatha iNoliprel Forte.

INoliprel Forte ayenqatshelwe ukuthatha ngesikhathi sokukhulelwa.

Lapho uncelisa ibele, kwenqatshelwe ukuqala ukwelashwa ngeNoliprel Forte.

INoliprel Forte imiselwe iziguli ezinesifo sikashukela.

Umuthi kufanele uphuzwe isikhathi esingu-1 ngosuku ngethebhulethi eyi-1.

Ukuthatha umuthi wesifo sikashukela

INoliprel Forte imiselwe iziguli ezinesifo sikashukela. Ngohlobo 2 sikashukela, ukwelashwa kuqala ngomthamo omncane ngaphansi kokuqashwa ngudokotela ngokuqinile. Ukuqapha njalo kokuhlushwa kwe-glucose kuyadingeka.

Imiphumela emibi

Ngesikhathi sokwelashwa, ukuphazamiseka kwemisebenzi ehlukahlukene yomzimba kungenzeka.

Amapheshana wesisu

Kungenzeka kube khona ukungakhululeki esiswini, ukuhlanza. Imvamisa kuba khona isicanucanu, umlomo owomile, izitulo ezikhululekile, ukunyakaza kwamathumbu okubambezelekile, ukushisa kwenhliziyo. Kwezinye izimo, ukuvuvukala kwamanyikwe, ukukhuphuka kwama-transaminases ne-bilirubin egazini.

Izitho zeHematopoietic

Ukwehla kwe-hemoglobin, ukwehla kokuxineka kwamaplatelet, ukwehla kwe-hematocrit, i-agranulocytosis, isici ekuthuthukisweni komongo wamathambo. Ezimweni ezingavamile, ukwehla kokuxineka kwe potassium kwenzeka.

Isistimu yezinzwa ephakathi

Kukhona ukukhala ezindlebeni, isiyezi, izinhlungu emathempelini, i-asthenia, ukuphazamiseka kokulala, ukuzikhulula kwemisipha ngokungazweli, ukungazizwa kwemizwa, i-anorexia, ukungasebenzi kahle kokunambitha, ukudideka.

Ukusetshenziswa kweNoliprel Forte kungahle kuhambisane nokwenzeka kokungakhululeki esiswini.

Ngokuphikisana nesizinda sokuphuza umuthi, ukuhlaselwa inhlokomo kanye nokuhlanza kungenzeka.

Ukuthatha umuthi kungahle kuhambisane nezitofu ezikhululekile.

Ukungaphenduki kahle komzimba kuNoliprel Forte kungabonakala njengokukhala ezindlebeni.

Ngemuva kokuthatha umuthi, ezinye iziguli zithola isiyezi.

Kwezinye izimo, ukuthatha lo muthi kuhambisana nokuqubuka kwamanyikwe.

Kusuka ohlelweni lomchamo

Ezimweni ezingavamile, i-proteinuria kanye ne-renal ephazamisayo umsebenzi kwenzeka, futhi ukunyuka kwe-plasma creatinine.

Kusuka ohlelweni lokuphefumula

Ukukhwehlela, ukuphefumula, i-bronchospasm, ukukhuphuka kwe-mucus ezindimeni zamakhala.

Ukusuka kubhalansi wamanzi we-electrolyte

Ukwanda kwe-plasma kwe-potassium kuyenyuka.

Allergies

Ukusabela kwe-allergic kungenzeka ngesimo sokuqubuka kwesikhumba, ubomvu, ukulunywa, okhalweni, ukuvuvukala, ukusabela kwe-photosensitivity.

Imiyalo ekhethekile

Ukusetshenziswa kwomuthi kuholela ekunciphiseni okukhulu komfutho wegazi emasontweni ama-2 okuqala ukwelashwa. Ngalesi sikhathi, ngaphansi kokuqondisa kukadokotela, iziguli ezinokwehluleka kwenhliziyo, kwehle ukujikeleza kwegazi kwegazi, ukungasebenzi kahle kwezinso, ukuqina kwesibindi, kanye ne-arterial stenosis kufanele kugcinwe. Kuyadingeka ukuqapha ukugcwala kwama-electrolyte. Ebudaleni nasekuphikiseni isizinda sezinye izifo, ubungozi be-hypokalemia buyanda.

Lapho kwenzeka imiphumela emibi, umthamo uyancishiswa noma unqanyulwe.

Kufanele uyeke ukuthatha lo muthi amahora angu-12 ngaphambi kokuhlinzwa. Mhlawumbe ukuthuthukiswa kwe-gout kubantu abane-uric acid ephezulu egazini. Kwi-plasma yegazi, ukugcwala kwe-urea ne-creatinine kunganda. Ngokusebenza okujwayelekile kwezinso, isimo siyabonakala, futhi uma kwenzeka sephulwa, ukwamukelwa kuyemiswa.

Lapho usebenzisa umuthi, ungahlangabezana nokubonakaliswa okungekuhle njengokukhwehlela.

Ukusabela komzimba kulo muthi kubonakaliswa ukulunywa, i-rash, i-urticaria.

Ngemuva kokuthatha umuthi, i-gout ingaqhamuka kubantu abane-uric acid egazini.

Ukuhlanganisa umuthi notshwala akuvunyelwe.

INoliprel Forte inethonya elibi kwikhono lokushayela imoto.

Ukuhambisana notshwala

Ukuhlanganisa umuthi notshwala akuvunyelwe.

Umthelela ekhonweni lokulawula izindlela

Kunomphumela omubi ekhonweni lokulawula izindlela ezenzelwe ukwenziwa. Thatha ngokuqapha.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Umuthi uphambaniswe ngesikhathi sokukhulelwa nangesikhathi sokuqunjelwa.

Sebenzisa ebudaleni

Umuthi usetshenziswa ngokuqapha lapho uguga. Ngaphambi kokuthatha, kubalulekile ukuhlola izinso futhi uhlole ukugcwala kwe-potassium ku-plasma yegazi.

Ukuqokwa kweNoliprel Forte yezingane

Kuze kube seminyakeni engu-18 yobudala, lesi sidakamizwa asinqunyelwe.

Iziguli zokwehluleka kwezinso

Ezimweni ezinzima, ungabeki. Iziguli ezinokwehluleka kokulinganisa kwe-renal zinqunywa kumithamo emincane.

Ukweqisa

Uma kwenzeka kweqa ngokweqile, kuzokwehla umfutho. Ukwehla kwesimo esijwayelekile kungahle kuhambisane nomcanucanu, ukuhlanza, isiyezi. Kukhona ukuqwasha, ukweqiwa, ukungakwazi ukuchama, ukubamba ishayela. Phambi kwalezi zimpawu, kuyadingeka ukuthi uhlambe isisu uthathe i-adsorbent.

Kuze kube yiminyaka engu-18 ubudala, iNoliprel Forte ayinqunyelwe.

Umuthi iNoliprel Forte usetshenziswa ngokuqapha lapho usumdala.

Ezigulini ezihluleka ukwehluleka kwezinso, iNoliprel Forte ichazwe kumthamo omncane.

I-overdose yeNoliprel Forte ingadala ukuquleka.

Ukweqa umthamo weNoliprel Forte kungadala ukuqwasha.

Uma kwenzeka okweqa ngokweqile kweNoliprel Forte, kuyadingeka ukuhlanza isisu.

Ukuxhumana nezinye izidakamizwa

Akunconywa ukuhlanganisa namalungiselelo e-lithium ne-potassium, i-potassium-sparing diuretics, i-glycosides ye-cardiac, i-Indapamide, izidakamizwa ze-antiarrhythmic, ama-iodine aqukethe i-iodine.

Umphumela wesidakamizwa uyancipha uma uhlanganiswa nama-glucocorticosteroids, i-Tetracosactide. Umphumela womenzeli we-antihypertensive ngokuhlanganiswa nama-tetracyclic antidepressants nama-antipsychotic uyothuthukiswa.

I-potasium iyanda ngenkathi kuthathwa usawoti we-calcium. I-cyclosporin ikhuthaza ukuthuthukiswa kwe-hypercreatininemia. Ukwanda kokubekezelela i-glucose kwenzeka ngokusetshenziswa kanyekanye ne-ACE inhibitors.

Ama-Analog

Ikhemisi lithengisa izidakamizwa ngomphumela ofanayo. Lokhu kufaka lokhu okulandelayo:

• Perindopril-Indapamide Richter;
• I-Perindide;
• I-Perindapam;
• I-Perindide;
• URenipril GT;
• I-Burlipril Plus;
• I-Enzix;
• I-Noliprel A Forte (5 mg perindopril arginine ne-1,25 mg indapamide);
• I-Noliprel A Bi-Forte (10 mg perindopril arginine kanye ne-2,5 mg indapamide).

Ngaphambi kokufaka esikhundleni se-analog, kubalulekile ukutadisha imiyalo futhi uvakashele uchwepheshe.

Uyini umehluko phakathi kweNoliprel neNoliprel Forte?

Umehluko enanini lezinto ezisebenzayo. Ukuqanjwa kwesidakamizwa ngaphandle kwemiyalo eyengeziwe ekupakweni kweForte kuqukethe i-2 mg ye-perindopril ne-0.625 mg ye-indapamide.

Imibandela Yokuphumula Yekhefu leNoliprela Forte

Ikhishwa ngemithi kadokotela.

Ngingakwazi ukuthenga ngaphandle kadokotela?

I-over-counter ayithengiswa.

Intengo

Izindleko zokufakwa ngama-ruble angama-530.

Izimo zokugcina zomuthi

Gcina umuthi emazingeni okushisa aze afike ku-30 ​​° C ekuhlanganisweni kwawo kwangempela.

Isikhathi sokuphelelwa yisikhathi

Isikhathi sokuphelelwa yisikhathi iminyaka engu-2

Eziqondisweni zesakhiwo somuthi, esifana nento esebenzayo, faka i-Berlipril Plus.

Lowo obambele isikhundla kungenzeka abe yiPerindopril-Indapamide Richter.

Abangaphansi ngemishini yokwenza efanayo kufaka phakathi i-Perindid yezidakamizwa.

I-Enzix inomphumela ofanayo emzimbeni oya eNoliprel Forte.

Ungasifaka isidakamizwa umuthi onjengeRenipril GT.

Ukubuyekezwa ku-Noliprel Fort

Izazi zezenhliziyo

Anatoly Yarema

Inhlanganisela ye-ACE inhibitor ne-diuretic yisisombululo esihle kakhulu sehypertension. Ithuluzi liholela ku-vasodilation, ukuncipha kokuxineka kwe-aldosterone kanye nokwehla kwe-hypertrophy yesinxele sobunxele. Ngokusebenzisa isikhathi eside, kuvimbela ukwenzeka kwezinkinga ezingena emzimbeni. Ukusabela okuncane okuncane okulandela imiyalo.

U-Evgeny Onishchenko

Umuthi uthuthukisa isimo semithambo yegazi, wehlise umthwalo enhliziyweni. Iziguli ezibuthakathaka nezigulayo kufanele zithathwe ngokucophelela. Inkambo yokwelashwa okungenani izinsuku ezingama-30. Kunconywa ukuthi uhlolwe kuqala. Umuthi unomphumela obekiwe uma uqhathaniswa ne-enalapril.

Iziguli

UVitaliy, oneminyaka engama-56

Umuthi obekiwe we-hypertension ye-arterial. Ingcindezi yokusebenza i-140/90, kwathi ngesikhathi sokuhlasela yafika kuma-200 nangaphezulu. Amaphilisi anciphisa ukucindezela ngokushesha. Ngiyithatha kanye ngosuku futhi angibonanga imiphumela emibi.

Elena iminyaka engama-44

Umuthi awuzange uwanane. Isebenza kancane futhi inesikhathi sokuvuka futhi. Ukuchama kaningi, i-tachycardia kanye nezitulo ezixegayo kunomphumela ovela ekwamukelweni. Ngithathe amasonto ama-2, kepha kwadingeka ngiyeke ukuyithatha.