Wonke umuntu uyazi ukuthi ukwelashwa kwesifo sikashukela ngokungafanele noma okungasebenzi kahle kungaholela ekuphazamiseni uhlelo lwezinzwa.
Manje izindlela ezimbili ziyathandwa - uTiogamma noThioctacid, okudingeka ukuqhathanisa ukuphendula umbuzo wokuthi yisiphi isidakamizwa esisetshenziswa kangcono kwi-neuropathy yesifo sikashukela.
Njengoba le mishanguzo iluhluzo, kuzobhekelwa kakhulu kulo muthi iTiogamma, futhi izinkomba zayo ngokunembile, imibiko, imiphumela emibi, amanani, ukubuyekezwa kwamakhasimende kanye nokufana.
Izici ezijwayelekile zomuthi
I-Thiogamma iyithuluzi elisiza ukuqinisa izinqubo ze-metabolic. Izwe okuvela kulo muthi yiJalimane. Ikhiqizwa ngesimo se:
- amaphilisi
- isixazululo sokufakwa (in dropers);
- gxila kakhulu ekwenzeni isisombululo se-infusion (umjovo wenziwa nge-ampoule).
Izibhebhe ziqukethe into esemqoka - i-thioctic acid, kusisombululo sokufakwa - usawoti we-meglumine we-thioctic acid, kanye nokugxila kwe-infusions yangaphakathi - i-meglumine thioctate. Ngaphezu kwalokho, uhlobo ngalunye lwesidakamizwa luqukethe izakhi ezihlukile zokusiza.
I-Thioctic acid (igama lesibili i-alpha lipoic) iyi-antioxidant eyenziwe emzimbeni. Yehlisa ushukela wegazi futhi yenyusa amazinga e-glycogen esibindini, wona, onqoba ukumelana ne-insulin. Ngaphezu kwalokho, i-thioctic acid ilawula ukusebenza kwe-lipids, ama-carbohydrate ne-cholesterol. Kuthuthukisa ukusebenza kwesibindi kanye ne-trophic neurons, kuphumuza umzimba ubuthi. Ngokuvamile, i-alpha lipoic acid inemiphumela elandelayo:
- i-hepatoprotective;
- ukwehliswa kwe-lipid;
- hypocholesterolemic;
- hypoglycemic.
Ekwelashweni kwesifo sikashukela, i-alpha-lipoic acid ijwayela ukuhamba kwegazi okungapheli, ikhuphule amazinga e-glutathione, ngenxa yalokho, ukusebenza kwezicubu zezinzwa kuyathuthuka.
I-Thioctic acid isetshenziswa kabanzi ngezinjongo zokugcoba: isula imibimbi ebusweni, inciphisa ukuthambeka kwesikhumba, iphulukise izibazi, kanye nomkhondo womqubuko, futhi iqinise ama-pores.
Imiyalo yokusebenzisa umuthi
Ngaphambi kokuthatha lo muthi, kufanele wazi ukuthi yimaphi ama-pathologies asetshenziselwa wona. Izinkomba zokusetshenziswa kwesidakamizwa iTiogamm yilezi:
- I-neuropathy yesifo sikashukela ukwephula uhlelo lwezinzwa maqondana nokunqotshwa kwemithambo yegazi emincane ezigulini ezinesifo sikashukela i-mellitus.
- I-Polyneuropathy iyi-lesion eminingi yokuphelela kwezinzwa.
- I-pathologies yesibindi - i-hepatitis, i-cirrhosis, ukonakala kwamafutha.
- Ukulimala kokuphela kwezinzwa ngenxa yokusebenzisa kabi utshwala.
- Ukufakwa emzimbeni (amakhowe, usawoti wezinsimbi ezisindayo, njll.).
Ukusetshenziswa kwesidakamizwa kuya ngesimo saso sokukhululwa. Isibonelo, amaphilisi (600 mg) athathwa ngomlomo, ngaphandle kokuhlafuna nokuphuza ngamanzi, kanye ngosuku. Inkambo yokwelashwa ihlala izinyanga ezi-1 kuye kwezingu-2, kuya ngobucayi besifo. Ukwelashwa okuphindayo kunconywa izikhathi ezingama-2-3 ngonyaka.
Ukwethulwa kwesidakamizwa uTiogamma Turbo kwenzeka ngokungamzali ngokwe-infravenous drip infusion. I-ampoule iqukethe ama-600 mg wesisombululo, umthamo wansuku zonke yi-1 ampoule. Umuthi uphathwa kancane ngokwanele, imvamisa cishe imizuzu engama-30, ukugwema ukusabela okubi okuhambisana nokufakwa ngokushesha kwekhambi. Inkambo yokwelashwa ihlala amasonto amabili kuya kwayi-4.
Ukugxila kwekhambi lokungeniswa kulungiselelwe ngale ndlela elandelayo: 1 ampoule (600 mg) yokulungiswa kweTiogamma kuxutshaniswe ne-50-250 mg yesisombululo se-sodium chloride (0.9%). Ngemuva kwalokho, inhlanganisela elungiselelwe ebhodleleni imbozwe icala elivikela ukukhanya. Ngokulandelayo, isixazululo sikhishwa ngokushesha ngaphakathi kwethambo (cishe imizuzu engama-30). Isikhathi sokugcina esiphezulu sesisombululo esilungiselelwe amahora angama-6.
Umuthi kumele ugcinwe endaweni emnyama engatholakali ezinganeni ngamazinga okushisa angadluli ku-25C. Impilo yamashalofu yalo muthi iminyaka emi-5.
Imithamo iyalinganiselwa. Udokotela oholayo kuphela ongakunikeza ukwelashwa nalesi sidakamizwa, athuthukise irejimenti yokwelashwa futhi abale umthamo ngokuya ngezimpawu zomuntu ngamunye ogulayo.
Contraindication kanye nemiphumela emibi
Kwesinye isikhathi ukusetshenziswa kwesidakamizwa akunakwenzeka. Lokhu kungenxa yokuphambanisa okuhlukahlukene okufana:
- ukungabekezelelani ngakunye ezintweni ezakhiwayo;
- izingane ezingaphansi kweminyaka engu-18;
- isikhathi sokukhulelwa nokuqunjelwa;
- ukwephulwa kwezinso noma isibindi (ikakhulukazi i-jaundice);
- ukwehluleka kwenhliziyo nokuphefumula;
- i-hyperacid gastritis noma i-peptic ulcer;
- infarction myocardial;
- uphuzo oludakayo;
- i-exsicosis kanye nomzimba;
- ukuphazamiseka kokujikeleza ebuchosheni;
- ushukela ongalawulwa yizidakamizwa (ifomu elibolile);
- kusengaphambili kwe-lactic acidosis;
- i-glucose-galactose malabsorption.
Ngokusebenzisa kabi isidakamizwa noma i-overdose, imiphumela eminingi engathandeki ingahle ivele, ngokwesibonelo:
- Ama-pathologies ahambisana nokuhlangana kwegazi: ukuqubuka kwe-hemorrhagic, i-thrombocytopenia, i-thrombophlebitis.
- Ukuphazamiseka kwesistimu yezinzwa: izinhlungu ekhanda nesiyezi, ukukhuphuka kokujuluka, ukukhishwa inyumbazane (akuvamile).
- Ama-pathologies ahambisana nezinqubo ze-metabolic: ukulimaza okubukwayo, okuvame ukubonakaliswa njenge-diplopia.
- Ukuphazamiseka kwendlela yokugaya ukudla: isisu esibuhlungu, ukushayeka kwenhliziyo, isicanucanu, ukugabha, ukuthopha, ukuhanjiswa yisisu.
- Ukuphendula kwe-allergic: redness yendawo, i-urticaria noma i-eczema endaweni lapho kwenziwa khona umjovo, ukushaqeka kwe-anaphylactic (ezimweni ezingavamile).
- Lapho kwethulwa ngokushesha umuthi: umfutho wegazi okhuphukile, umjikelezo wokuphefumula okhubazekile.
Ngaphezu kwalokho, ukwethulwa kwekhambi noma ukusetshenziswa kwamathebulethi kumithamo emikhulu kungaholela kwimiphumela enjalo:
- ukuphazamiseka kwengqondo
- ukwehluleka
- ukubanjwa kwesithuthwane;
- i-lactic acidosis;
- ukwethuka;
- i-hypoglycemic coma;
- ukucindezelwa kwamathambo;
- ukwehluleka kwezitho eziningi;
- esisabalalisa intravascular coagulation syndrome.
Ukuphendula okuhlukile kumele kubhekwane nakho kususelwa kuzimpawu. Uma kusetshenziswe amaphilisi, kuzodingeka ukuthulula isisu. Kulokhu, ama-enterosorbents (ngokwesibonelo, kusetshenziswa ikhabhoni ekhiqizwa) kanye nama-ejenti wokuhlanza. Uma umuthi wawuphethwe ngobuzali futhi wabangela ukuphathwa ikhanda, ama-analgesics kufanele asetshenziswe. Uma isiguli sinokutholwa, i-lactic acidosis kushukela, khona-ke kufanele kusetshenziswe ukunakekelwa okuqinile.
Ngakho-ke, ngaphambi kokusebenzisa umuthi, udinga ukubonana nodokotela futhi ufunde ngokucophelela imiyalo enamathiselwe.
Amanani kanye nokubuyekezwa kwezidakamizwa
Izindleko zomuthi zincike ohlotsheni lwayo lokukhululwa. Ngakho-ke, intengo yamathebulethi (izingcezu ezingama-30 zama-600 mg) ziyehluka kusuka kuma-ruble ayi-850 kuya kuma-960. Izindleko zesisombululo se-infusion (ibhodlela elilodwa) zisukela kuma-ruble ayi-195 kuye kwangama-240, ukugxila kokufakwa kwangaphakathi cishe ngama-ruble angama-230. Ungathenga umuthi cishe kunoma iyiphi ikhemisi.
Ukubuyekezwa kodokotela neziguli mayelana nomuthi iTiogamma kungcono. Umuthi uthandwa kakhulu ekwelapheni isifo sikashukela nasekuvimbeleni i-neuropathy. Odokotela abaningi bathi akufanele ungesabi uhlu olukhulu lwe-contraindication kanye nemiphumela emibi. Eqinisweni, ukusabela okungekuhle kwenzeka kakhulu kakhulu - isikhathi esingu-1 ngamacala ayi-10,000.
Ngokuya ekubuyekezweni kwabathengi kwaleli thuluzi, izinzuzo ezilandelayo zingahlukaniswa:
- ukusetshenziswa kalula kwamathebhulethi, isikhathi esisodwa kuphela ngosuku;
- inqubomgomo yentengo ethembekile;
- inkambo emfushane yokwelashwa.
Odokotela bavame ukunquma isidakamizwa iTiogamma ngendlela yesisombululo sokufakwa ngaphansi kwezimo zokuma. Umuthi unomphumela osheshayo wokwelapha futhi empeleni awubangeli imiphumela emibi.
I-Thiogamm futhi ibhekwa njengomkhiqizo osetshenziswayo wokugcoba. Iningi leziguli lithi umuthi empeleni ubhekana nemibimbi.
Kepha kwezinye izimo, ukungaphenduki komzimba okufana nokubomvu nokulunywa kungenzeka.
Uhlu lwezidakamizwa ezifanayo
Uma isiguli singawubekezeleli lo muthi noma sinemiphumela emibi, ukusetshenziswa kwalesi sidakamizwa kuyodingeka kuyekwe.
Udokotela angabeka esinye isidakamizwa esifanayo esizoqukatha i-thioctic acid, ngokwesibonelo:
- I-Thioctacid isetshenziswa ikakhulukazi ekwelashweni kwezimpawu ze-neuropathy noma ze-polyneuropathy ngendlela engapheli yezidakwa nothukela. Umuthi ukhishwa ngendlela yamathebulethi bese ugxila. Ngokungafani neTiogamma, iThioctacid ine-contraindication embalwa kakhulu, okubandakanya isikhathi sokukhulelwa kuphela, ukuncelisa, ubudala bezingane nokungabekezelelani ngakunye ezingxenyeni zomuthi. Izindleko zomuthi ngendlela yamathebulethi zingama-ruble ayi-1805, kanye nama-ampoules wokufaka ngaphakathi - ama-ruble ayi-1530.
- I-Berlition inomphumela omuhle emzimbeni womuntu, njengoba isheshisa imetabolism, isiza ukumunca amavithamini nezakhi zomzimba, iqinise i-carbohydrate kanye nama-metabolism wamafutha, futhi ibuye isebenze ngokwejwayelekile ukusebenza kwezixha ze-neurovascular. Umuthi ukhishwa ngendlela yama-ampoules kanye namathebulethi. Izindleko ezijwayelekile zama-ampoules ngama-ruble angama-570, amaphilisi - ama-ruble ayi-765.
- I-Lipothioxone iyindawo yokugxila kwekhambi lokufakwa kokunye okusetshenziswa ku-polyneuropathy yesifo sikashukela kanye notshwala. Angeke isetshenziswe ezinganeni ezingaphansi kweminyaka engu-6 ubudala, futhi ngesikhathi sokukhulelwa, ukusetshenziswa komuthi kuvunyelwe uma umphumela wezokwelapha udlula ingozi ebusaneni. Intengo ephakathi yalesi sidakamizwa ama-ruble angama-464.
- I-Oktolipen umuthi osetshenziselwa ukumelana ne-insulin, ushukela wegazi ophakeme nokwandisa i-glycogen esibindini. Umuthi ngesimo samathebulethi, amakhompiyutha nokugxila kwekhambi uyatholakala. Intengo ejwayelekile yesidakamizwa emaphaketheni ngama-ruble angama-315, kumathebulethi - ama-ruble angama-658, kuma-ampoules - ama-ruble angama-393. I-Oktolipen yohlobo 2 sikashukela i-mellitus ingahlanganiswa ngempumelelo ne-metformin namanye ama-hypoglycemic agents.
Ngokusekelwe ku-contraindication kanye namathuba wezezimali, isiguli sinikezwa ithuba lokukhetha inketho enhle kakhulu ezoba nemiphumela ephumelelayo yokwelapha.
Futhi-ke, iTogogma iyisidakamizwa esisebenzayo ekwelapheni i-neuropathy yesifo sikashukela kanye nezinye izifo ezibucayi. Umuthi wayo osebenzayo, i-thioctic acid, uthinta ngempumelelo i-metabolism yamafutha kanye nama-carbohydrate, unciphisa glucose wegazi, ukhuphula okuqukethwe kwe-glycogen esibindini kanye nokuzwela kwezicubu ze-peripheral to insulin. Umuthi utholakala ngezindlela eziningi. Lapho usebenzisa lesi sidakamizwa, kufanele ulandele izincomo zikadokotela, ngoba ezimweni ezingafani kakhulu ukusabela okungekuhle kungenzeka. Ngokuyisisekelo, ithuluzi liphendulwa kahle, ngakho-ke lingasetshenziswa ngokuphephile ukwenza ukusetjenziswa kohlelo lwezinzwa kube lula.
Izinzuzo ze-lipoic acid zesifo sikashukela zichazwe kuvidiyo kule ndatshana.
