Amaconsi eshiya we-Gentamicin yi-topical antibiotic. Ngenxa yokusebenza kwayo okuphezulu nentengo ephansi, amaconsi asetshenziswa kabanzi e-ophthalmology ekwelapheni izifo zamehlo.
Igama Lezwe elingafanele
Igama elithi gentamicin lamukelwa njengelingengomphathi wamanye amazwe.
Amaconsi eshiya we-Gentamicin yi-topical antibiotic.
Ath
Umuthi ungowokulwa namagciwane, ama-aminoglycosides, anekhodi ye-ATX J01GB03.
Ukwakheka
Into esebenzayo yesidakamizwa yi-glamicin sulfate. Ukwakheka okusizayo kufaka phakathi izinto ezimbalwa:
- I-Trilon B (lolu usawoti we-disodium we-ethylenediaminetetraacetic acid);
- sodium hydrogen phosphate;
- amanzi ngomjovo.
Ukupakishwa kumelelwa ngebhodlela lepulasitiki kanye nenqwaba yamakhadibhodi.
Isenzo se-Pharmacological
Le antibiotic inezinto eziningi ezisebenzayo futhi inempahla ebactericidal. Lapho usebenzisana nama-bacterium, into esebenzayo ingena kolwelwesi lweseli futhi ihlangabezana ne-30S subunit yama-bacterial chromosomes. Njengomphumela walesi senzo, ukwephulwa kokuhlanganiswa kweprotheni kwenzeka.
Ukupakishwa kumelelwa ngebhodlela lepulasitiki kanye nenqwaba yamakhadibhodi.
Izinhlobo ezilandelayo zama-microorganisms zizwela umuthi:
- shigella;
- E. coli;
- i-salmonella;
- Klebsiella;
- i-enterobacteria;
- izivumelwano;
- Pseudomonas aeruginosa;
- Amagciwane ama-Proteus;
- i-gram-negative bacterial acinetobacter;
- staphylococci;
- ezinye izingqinamba ze-streptococcus.
Ithuluzi lenzelwa ukwelashwa kokushiswa kwamehlo.
Ukumelana nokwakheka kombukiso wezidakamizwa:
- i-meningococcus;
- amabhaktheriya e-anaerobic;
- izinhlobo ezithile ze-streptococci;
- I-treponema iphuzi.
I-Pharmacokinetics
Lapho isetshenziswa ngokweqile, into esebenzayo idonswa ngokushesha. Ukuhlushwa okuphezulu kufinyelelwa ngemuva kwemizuzu engama-30-60 ngemuva kokusebenzisa amaconsi. Ngamaprotheni e-plasma, ukubopha okuphansi kuyabonakala, yi-0-10% kuphela.
Ukusatshalaliswa kwalesi sidakamizwa emzimbeni wonke kwenzeka ku-extracellular fluid. Ukuphila kwengxenye kwento kufinyelela emahoreni angama-2-4. Iningi lama-mnene lifakwa ezinsweni futhi lincane kakhulu isibindi.
Asetshenziselwa ini ama-Gentamicin?
Lamaconsi ngokuvamile abekelwe izifo ezithathelwanayo ezibangelwa amagciwane azwela umuthi. Kulokhu, ukuxilongwa kuyadingeka.
Lamaconsi avame ukubekelwa i-keratitis.
Uhlu lokuxilongwa umuthi olusebenzayo:
- i-keratitis;
- i-blepharitis;
- ukushisa kwamehlo;
- i-conjunctivitis;
- iridocyclitis;
- ukulimala kwamakhemikhali emehlweni;
- isilonda somhubhe.
Ngezinjongo zokuvimbela, umuthi unqunywa ngaphambi kokuhlinzwa emehlweni nangemva kwawo. Izenzo ezinjalo zivimbela izinkinga futhi zinciphise isikhathi sokululama.
Contraindication
Ngaphambi kokusebenzisa, kufanele uzijwayeze nemiyalo ngokuningiliziwe, ngoba amaconsi wamehlo anokuphikisana okulandelayo:
- hypersensitivity kuzakhi zokwakheka;
- umlando wokungezwani komzimba kuma-aminoglycosides;
- izingane ezingaphansi kweminyaka engu-8;
- isikhathi sokukhulelwa nokukhulelwa;
- ukulimazeka okukhulu kwezinso;
- i-nerve ye-nerve neuritis;
- myasthenia gravis.
Odokotela baxwayisa ngengozi yokutheleleka kwesibili ngokusebenzisa amaconsi isikhathi eside. Ngalesi sizathu, ukuqokwa kumele kuqashelwe ngokuqinile.
Ngokunakekela
IGentamicin icutshaniswe nezifo ezinzima zezinso ezihambisana nokuphulwa komsebenzi wazo. Ngokuphambuka okuncane, umuthi unqunyelwe ngokuqapha. Kulokhu, udokotela kumele akhethe ngokuqondile umthamo womuthi futhi aqaphe njalo umsebenzi wezinso.
Imithamo nendlela yokuphathwa kwamaconsi eGentamicin
Amaconsi asetshenziselwa ukufakwa kwi-conjunctival sac. Izingane ezineminyaka engaphezu kwengu-8 ubudala nabadala banconyelwe ukufaka ama-1-2 amaconsi esweni ngalinye. Imvamisa yokusetshenziswa izikhathi ezingama-3-4 ngosuku. Kungcono ukuphuza umuthi ngezikhathi ezithile.
Isikhathi sesifundo sincike kuhlobo lwesifo kanye nobukhali baso futhi kuthatha isilinganiso sezinsuku eziyi-14.
Ngokuvimbela, sebenzisa uhlobo olwahlukile lomthamo. Ukunciphisa ingozi yokutheleleka, umuthi ufakwa kwehla i-1 izikhathi ezi-4 ngosuku. Isikhathi sokusetshenziswa - izinsuku ezi-3.
Amaconsi afanele ukusetshenziswa kwe-topical kuphela. Ukuzisebenzisa ukufakwa ekhaleni nasezindlebeni akunconyiwe. Ngalezi zinhloso, kunezinye izidakamizwa ezingamaconsi ayinkimbinkimbi (endlebeni nasekhaleni) ene-mosaamicin ekwakhiweni.
Ukuthatha umuthi wesifo sikashukela
Lapho welapha iziguli ezinesifo sikashukela, amaconsi anqunywa ngokuqapha. Ukwelashwa kwenziwa ngaphansi kokuqondisa udokotela.
Lapho welapha iziguli ezinesifo sikashukela, amaconsi anqunywa ngokuqapha.
Imiphumela emibi yamaconsi eGentamicin
Ngokuya ngezincomo zikadokotela, amaconsi wamehlo abekezelelwa kahle. Imiphumela emibi ihlala yenzeka ngenxa ye-hypersensitivity kuzakhi zomuthi. Uhlu lwezimpawu ezinokwenzeka:
- ubomvu bamehlo;
- i-lacrimation
- ukuzwela ukukhanya;
- ukulunywa kanzima;
- umuzwa ovuthayo emehlweni;
- ezimweni ezingavamile, i-thrombocytopenic purpura iyabonakala (ukuthambekela kokuphuma kwe-mucous membranes yezitho zombono);
- ama-hallucinations (akuvamile kakhulu).
Uma amaconsi engasetshenzisiwe ngokuya ngemiyalo, isiguli singabona i-lacrimation.
Uma kutholakala uphawu olulodwa noma olunye oluphikelelayo, kufanele wenqabe ukuthatha umuthi. Thintana nomhlinzeki wakho wezokunakekelwa kwezempilo ukuze uthole izincomo.
Umthelela ekhonweni lokulawula izindlela
Ukusetshenziswa kwesidakamizwa kunganciphisa i-acuity ebonakalayo. Lokhu kuchazwa ubukhona be-lacrimation. Mayelana nalesi sici, ekwelapheni izifo zamehlo, umuntu kufanele enqabe ukushayela imoto nokulawula ezinye izindlela.
Imiyalo ekhethekile
Iziguli ezigqoka amalensi okuxhumana kufanele zikhiphe ngaphambi kokusetshenziswa. Nakulokhu, zingafakwa kuphela imizuzu eyi-15 ngemuva kokufakwa kwamehlo. Lokhu kuchazwa iqiniso lokuthi i-benzalkonium chloride ekwakhiweni komkhiqizo ibangela ukucasuka kwamehlo futhi iyakwazi ukushintsha umbala welensi ye-gel. Ezinye iziguli zisebenzisa izibuko ngesikhathi sokulashwa.
Lapho usebenzisa amaconsi, ungathinti phezulu kwe-vial (lapho umgodi ukhona). Lokhu kungaholela kumagciwane kusuka ezandleni ezingena kwi-conjunctiva yeso, okucasulayo ukutheleleka kwesibili.
Ngezifo ezinzima, odokotela bangase banikeze i-antibiotic yokusetshenziswa komlomo noma njengomjovo.
Sebenzisa ebudaleni
Uma kungekho okunye okuphikisana, iziguli esezikhulile zingafaka amaconsi ngokuya ngohlobo olujwayelekile lokwelashwa.
Isabelo sezingane
Ezinganeni ezingaphansi kweminyaka engu-8 ubudala, le antibiotic ayinconywa, kodwa ngokuxilonga okuthile kungenzeka. Ezimweni ezinjalo, izincomo zikadokotela kufanele zibhekwe ngokucophelela.
Ezinganeni ezingaphansi kweminyaka engu-8 ubudala, le antibiotic ayinconywa, kodwa ngokuxilonga okuthile kungenzeka.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
I-Gentamicin kufanele ichazwe ngesikhathi sokukhulelwa kuphela uma inzuzo kumama idlula engcupheni yokuthinta ingane. Nge-lactation, ukusetshenziswa kuvunyelwe kuphela enconyelweni kadokotela.
Ukweqisa
Ukweqisa umthamo wokwelapha kungadala ukuvuvukala komzimba we-corneal stroma. Ngalezi zimpawu, i-antibiotic imisiwe.
Ukuxhumana nezinye izidakamizwa
Ngokuvamile amaconsi asetshenziswa ngokuhlanganiswa neminye imithi (ye-sinusitis, i-otitis media nezinye izifo).
Ngama-corticosteroids kanye nama-antibalas nemiphumela ye-nephrotoxic ne-ototoxic, amaconsi angasetshenziswa, ngoba akukho ukusebenzisana okuqinile kwale mishanguzo okutholakele.
Ama-phosphates, ama-nitrate, ama-sulfates, ama-cations e-calcium, i-potassium, i-magnesium ne-sodium anciphisa ukusebenza kwamaconsi.
Ama-Analog
I-Gentamicin, ekhiqizwe kwezinye izinhlobo zomthamo, inomphumela ofanayo we-bactericidal: i-powder yokulungiswa kwemijovo, isixazululo somjovo. Kukhona namafutha namaphilisi.
Izidakamizwa ezilandelayo zinemiphumela efanayo:
- Taizomed;
- I-Kanamycin;
- Isofra;
- I-Gentamicin Dex.
Imibandela yekhefu lekhemisi
Umuthi uthengiswa emakhemisi ngokunikezwa umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Imithi ekuleli qembu ayithengiswa ngaphezulu kwekhawuntara.
Intengo
Izindleko zokwehla kwamehlo emakhemisi aseMoscow ziqala kuma-ruble ayi-150.
Izimo zokugcina zomuthi
Umuthi kufanele ugcinwe ekushiseni kwe + 15- + 25 ° C. Ukukhanya kwelanga okuqondile akuvunyelwe.
Isikhathi sokuphelelwa yisikhathi
Uma ivaliwe, impilo yeshalofu yesidakamizwa iyiminyaka emi-3. Ibhodlela elivulekile ukusetshenziselwa ligcinwa isikhathi esingadluli izinyanga ezingama-3-4.
Amaconsi eGentamicin angathathelwa indawo nge-Esofra.
Umkhiqizi
Lesi sidakamizwa senziwa yizinkampani zemithi eziningana ezivela ePoland, Russia naseSwitzerland.
Ukubuyekezwa
Ngokusho kokubuyekezwa, i -neneamicin ngendlela yamaconsi isetshenziswa kaningi, kuyilapho odokotela abaningi neziguli banelisekile ngomphumela.
Odokotela
Tatyana, ophthalmologist, isipiliyoni sezokwelapha iminyaka engu-8
I-Gentamicin ibhekana ngokushesha nokutheleleka ngegciwane, ngakho-ke kuvame ukubekelwa izifo ezithathelanayo zeso. Enye futhi intengo ephansi.
Vitaliy, ophthalmologist, isipiliyoni kwezokwelapha iminyaka engama-20
Lapho i-pathogen ibekezelela into esebenzayo, izimpawu zesifo ziqedwa ngokushesha. Lokhu kukhombisa ukusebenza kahle kwesidakamizwa. Kulesi simo, iziguli eziningi zithola ukusabela kokungezwani nokwakheka kwalo muthi. Uma kungenzeka, zama ukunquma ezinye izidakamizwa ezigulini.
Ukweqisa umthamo wokwelapha kungadala ukuvuvukala komzimba we-corneal stroma.
Iziguli
UMarina, oneminyaka engama-37, u-Astrakhan
Bekumele ngibone udokotela, njengoba amehlo abephenduka abomvu, ubomvu nokuwoma kwavela. I-Gentamicin ngesimo samaconsi inqunyelwe. Ngezwa kungcono ngosuku olulandelayo. Inkambo yokwelashwa yayiphelele.
UPeter, oneminyaka engama-44 ubudala, uKrasnodar
Ukwelashwa okungabizi kakhulu kwezifo zamehlo. Kusetshenziswe njengoba kuyalelwe udokotela. Imiphumela emibi ayenzekanga, ubomvu nokukhishwa kwe-purulent kwaqedwa ngemuva kwezinsuku ezimbalwa.
