I-Xenalten isiza ukunciphisa isifiso sokudla, inciphise ingozi yokuba nesifo sikashukela sohlobo 2 futhi iqale inqubo yokushisa amafutha. Kusetshenziswa ekwelapheni ukukhuluphala. Kuboniswa iziguli ezindala.
Igama Lezwe elingafanele
I-Orlistat
I-ATX
A08AB01
Umenzi ukhipha umuthi ngesimo samaphilisi, i-orlistat iyinto esemqoka enquma umphumela walesi sidakamizwa.
Khipha amafomu nokwakheka
Umenzi ukhipha umkhiqizo ngendlela yamaphilisi. I-Orlistat iyinto esemqoka enquma umphumela walesi sidakamizwa.
Isenzo se-Pharmacological
Umuthi uvimbela umsebenzi we-lipases. Ama-Enzymes aphelelwa amandla okubhidliza amafutha. Okuqukethwe kwekhalori kokudla kuyancipha, futhi amafutha akhishwa inyumbazana. Kunokwehla kwesisindo somzimba.
I-Pharmacokinetics
Alungenwa nhlobo emgudwini wokugaya ukudla. Akutholakali kuyi-plasma yegazi futhi akuqongeleli emzimbeni. Ibopha amaprotheni e-plasma futhi ingena kumaseli abomvu egazi. I-Biotransformed odongeni lwepheshana esiswini futhi ikhutshiwe ngendle.
Izinkomba zokusetshenziswa
Umuthi ubekelwe ukwelashwa nokuvinjwa kokukhuluphala nge-BMI ka-≥30 kg / m² noma ≥28 kg / m² ngokuhlanganiswa nokudla. Ingasetshenziswa ngemuva kohlobo 2 sikashukela mellitus, cholesterol ephezulu ye-plasma, umfutho wegazi ophezulu we-arterial.
Umuthi ubekelwe ukwelashwa nokuvimbela ukukhuluphala okuhambisana nokudla.
Contraindication
Akuvunyelwe ukuthatha amaphilisi wezifo ezithile nemibandela ethile:
- amathumbu malabsorption syndrome;
- hypersensitivity kuzakhi zomuthi;
- ukuqina kwe-bile;
- ukukhulelwa
- ukuncelisa.
Kufakwa emgqeni wokuqala ukwelashwa uma isiguli singaphansi kweminyaka engu-18.
Ngokunakekela
Ukuqapha kufanele kusetshenziswe ku-oxalate-calcium crystalluria kanye nesifo setshe lezinso.
Ungayithatha kanjani iXenalten
I-120 mg ithathwa ngaphambi kokudla ngakunye (hhayi ngaphezulu kwezikhathi ezi-3 ngosuku). Ungayithatha i-capsule ngemuva kokudla, kepha kungakapheli imizuzu engama-60. Uma ukudla kungenamafutha, ungakweqa ukwamukela. Isikhathi sokwelashwa sinqunywa ngudokotela.
I-120 mg ithathwa ngaphambi kokudla ngakunye (hhayi ngaphezulu kwezikhathi ezi-3 ngosuku), ungayithatha i-capsule ngemuva kokudla, kepha kungakapheli imizuzu engama-60.
Ngoshukela
Udinga ukuthatha ngokuya ngemiyalo. Ukweqisa umthamo ophakanyisiwe awukhulisi umphumela.
Imiphumela emibi ye-Xenalten
Ngesikhathi sokuphatha, imiphumela emibi ingenzeka inyamalala ngemuva kokuyeka umuthi.
Amapheshana wesisu
IStool iba ooli kuze kufike kuhudo. Imvamisa kuba nokuthopha, izinhlungu esiswini.
Kusuka emasosheni omzimba
Ithuluzi lingadala ukungezwani komzimba: ukulunywa kwesikhumba, ukuvuvukala kwezicubu ezingaphansi, kunciphisa ukukhanya kwe-bronchi, ukushaqeka kwe-anaphylactic.
Isistimu yezinzwa ephakathi
Ukukhathala, ukukhathazeka, ikhanda liyavela.
Kusuka ohlelweni lomchamo
Ukutheleleka kwezifo ze-urinary kungavela.
Kusuka ohlelweni lokuphefumula
Ngesikhathi sokwelashwa, ipheshana lokuphefumula elingaphezulu nelingezansi kakhulu lisengozini yokuthola isifo. Ukuvela kokukhwehlela kubonisa isifo esithathelwanayo.
Engxenyeni yesibindi ne-biliary
Ezimweni ezingavamile, umsebenzi we-alkaline phosphatase kanye ne-hepatic transaminases uyanda.
Kusuka ezinso nasegunjini lokuchama
Imvamisa - izifo ezithathelwanayo zezinso nepheshana lomchamo.
Umthelela ekhonweni lokulawula izindlela
Umuthi awuthinti amandla okulawula izindlela.
Imiyalo ekhethekile
Ngesikhathi sokwelashwa, udinga ukulandela indlela yokudla futhi unqande ukusetshenziswa kokudla okunamafutha. Ngaphandle kwalokho, imiphumela emibi evela emgodini wesisu ingavela. Kuyalulekwa ukudlala imidlalo nokwenza ukuqeqeshwa okujulile ukuze uthole umphumela omuhle kakhulu.
Ukuntuleka kwemiphumela ngemuva kwezinyanga ezintathu zokwelashwa kuyisikhathi sokubonana nodokotela. Inkambo yokwelashwa akufanele idlule iminyaka emi-2.
Lapho kukhona i-anorexia nervosa ne-bulimia, kungenzeka ukuthi kuphethwe kabi umuthi.
Abesifazane badinga ukusebenzisa izindlela zokuvimbela inzalo ngesikhathi sokwelashwa, ngoba ubungozi bokukhulelwa okungakahlelwanga luyanda.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ithuluzi alisetshenziswa ngesikhathi sokukhulelwa. Kuyaluleka ukuthi uyeke ukondla ngaphambi kokuqala ukwelashwa.
Ukuqokwa kukaXenalten ezinganeni
Kuze kube yiminyaka eyi-18, lesi sidakamizwa siyaphulwa.
Sebenzisa ebudaleni
Ayikho idatha ekusetshenzisweni ekugugeni.
Isicelo sokusebenza kokulimala kwezinso
Uma kwenzeka isifo sezinso sezinso ne-oxalate nephropathy, udinga ukubonana nodokotela ngaphambi kokuthatha.
Sebenzisa umsebenzi wesibindi okhubazekile
Uma i-cholestasis itholwa ngemuva kwesizinda sokungasebenzi kahle kwesibindi, umuthi uyaphulwa.
I-Xenalten overdose
Umuthi awubangeli zimpawu ezikhethekile uma umthamo unyusiwe.
Ukuxhumana nezinye izidakamizwa
Umuthi uxhumana nezinye izidakamizwa kanjena:
- amalungiselelo e-multivitamin kufanele athathwe amahora ama-2 ngaphambi noma ngemuva kokuthatha umuthi ukuze unciphise isisindo;
- ukuhlanganiswa kanyekanye ne-cyclosporine akunconywa;
- umuthi ukhulisa ukuqina kwePravastatin ku-plasma yegazi;
- I-Amiodarone ne-Orlistat kufanele zithathwe ngokuqapha;
- I-Acarbose ayinconywa ngesikhathi sokwelashwa.
Ukwehliswa komthamo kwama-ejenti we-hypoglycemic kungahle kudingekile.
Ukuhambisana notshwala
Ngokuphuza uphuzo oludakayo, imiphumela engemihle evela emgudwini wesisu inganda.
Ama-Analog
Uma ikhemisi lingenalo lo muthi, ungathenga i-analog:
- I-Xenical
- I-Orsoten;
- I-Orlistat.
Izidakamizwa ezifanayo zingadala imiphumela emibi, ngakho-ke kungcono ukubonana nodokotela ngaphambi kokuzisebenzisa.
Imibandela yekhefu lekhemisi
Ekhemisi udinga ukuletha incwadi kadokotela evela kudokotela wakho.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ikhefu elingaphezulu kwe-counter kungenzeka uma u-oda online.
Malini
Intengo yesidakamizwa eRussia iyahlukahluka kusuka kuma-ruble ayi-1,500. kufika ku-2000 rub.
Izimo zokugcina zomuthi
Kungcono ukugcina umkhiqizo ekufakweni kwawo koqobo kumazinga okushisa aze afike ku-25 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyiminyaka emi-2.
Ngokuphuza uphuzo oludakayo, imiphumela engemihle evela emgudwini wesisu inganda.
Umkhiqizi
I-CJSC Pharmaceutical Enterprise Obolenskoye, eRussia.
Ukubuyekezwa kweXenalten
Ithuluzi lisiza iziguli ukunciphisa umzimba, kanye ne-cholesterol ephansi noshukela wegazi. Ukubuyekezwa okungalungile kushiyelwa yiziguli ezingakwazanga ukunciphisa isisindo ngemuva kokuphazamiseka kwe-hormonal nezinye izimbangela ze-organic.
Odokotela
U-Evgenia Stanislavskaya, udokotela wamathambo
Umuthi ubekezelelwa kahle yiziguli. Kwezinye izimo, i-flatulence, ubuhlungu besisu kanye nezitulo ezixegayo kuyavela, kodwa izimpawu zisheshe zivele zodwa. Uma ukudla kungenamafutha, ungakwazi ukweqa ukuphuza amaphilisi, bese uqhubeka ngokohlelo. Uma kwenzeka ukungasebenzi kahle, kufanele uthintane nodokotela futhi uhlolwe.
U-Igor Makarov, isazi sezempilo
Ithuluzi alimazi umzimba futhi lisusa ngokuphelele amakhilogremu angaphezulu. Ukwelashwa kufanele kube okuphelele. Kufanele nakanjani ungene kwezemidlalo udle ngakwesokudla. Umuthi usiza ukunciphisa umzimba futhi wehlise nengozi yesifo sikashukela. Kungathathwa nesifo sikashukela sokunciphisa isisindo kanye nokwehlisa amazinga kashukela ngokuhambisana ne-Metformin nabanye. Uma ngemuva kwezinyanga ezi-3 bekungeke kwenzeka ukuthi ulahlekelwe yi-5% yesisindo somzimba, ukwamukelwa kuyemiswa.
Uma ikhemisi lingenayo i-Xenalten, ungathenga i-analog, isibonelo, i-Orsoten.
Iziguli
U-Elena, oneminyaka engama-29 ubudala
Ngosizo lwaleli thuluzi, kuvela ukuthi wehlise isisindo ngo-3.5 kg ngenyanga. Akenzanga mzamo, kepha waqala ukudla ukudla okuncane, okuqukethe amafutha. Ngosuku lwesibili lokwemukelwa, ngabona ukuthi i-stool iba oily, kwesinye isikhathi igesi yayiphazamisa. Umuthi ulwa nesifiso sokudla. Ngihlela ukuphuza umuthi okungenani izinyanga eziyisithupha. Ngijabule ngomphumela.
Ukulahlekelwa isisindo
UMaryana, oneminyaka engama-37
U-Orlistat Akrikhin waqala ukuthatha ngemuva kokuzalwa. Ngayithenga ekhemisi ngaphandle kadokotela futhi ngaqala ukuphuza i-1 ithebhulethi izikhathi ezintathu ngosuku ngemuva kokudla. Ezinyangeni ezi-4 ngilahlekelwe ama-7 kg. Ngaphezu kwalokho wabamba iqhaza kwezokuzivocavoca kwe-aerobic. Emiphumela emibi, ngabona ukungaphatheki kahle esiswini, okuma ngemuva kwamasonto amabili. Ngizizwa kahle futhi ngeke ngime lapho.
ULarisa, oneminyaka engama-40
Ngifunde ukubuyekezwa futhi nganquma ukuthenga umuthi. Ngiphuze amaphakethe ama-2 ngokuya ngemiyalo, kepha ngaphansi kwenqaku lama-95 kg, isisindo asinciphi. Muva nje, ucezu lwezinyo seluphumile - umuthi awuvumeli amavithamini namaminerali ukuthi ungenwe ngokujwayelekile. Nginqume ukuyeka ukuyithatha futhi ngizame ezinye izindlela.
