I-Acetylsalicylic acid acid (medisorb) isidakamizwa esidumile esingelona i-steroidal elwa nokuvuvukala sisetshenziselwa umkhuhlane kanye nokuqaqeka kwekhanda, izinyo lamazinyo nobunye ubuhlungu.
Igama Lezwe elingafanele
Acetylsalicylic acid (Acetylsalicylic acid).
I-Acetylsalicylic acid acid (medisorb) isidakamizwa esidumile esingelona i-antiidal.
I-ATX
I-N02BA Salicylic acid kanye nokuphuma kwayo.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo samacwecwe ahlanganiswe nengozi phakathi. Into ebalulekile esebenza yi-Acetylsalicylic acid. Phakathi kwezinto ezisizayo: isitashi, i-magnesium stearate, amanzi.
Isenzo se-Pharmacological
I-Acetylsalicylic acid isho izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala ezisetshenziselwa ukudambisa izinhlungu.
I-Pharmacokinetics
I-Absorption ivela emathunjini ngokugcwele. I-ASA isatshalaliswa kwezicubu njenge-anion ye-salicylic acid. Umuthi awuhlanganisiwe kuphela kuyi-plasma yegazi, kodwa nasezithanjeni ze-bone-cartilage, kanye noketshezi lwe-synovial (inter-Expressular).
I-Absorption ivela emathunjini ngokugcwele.
Ukusuka emzimbeni, umuthi ukhishwa ngendlela yama-metabolites esebenzisa uhlelo lwe-urinal. Izinga le-Excretion - lisuka emahoreni amabili kuya kwangama-30, kuya ngethamo.
Okusizayo
I-ASA inobubanzi obukhulu bezenzo, isusa izinqubo zokuvuvukala futhi inciphise nobuhlungu. Ngaphezu kwalokho, i-acid compounds inempahla yokunciphisa igazi, okudingekile ekwelapheni nasekuvimbeleni izifo zenhliziyo. Kulokhu, umuthi usetshenziselwa amacala alandelayo:
- ukukhuphuka kokushisa komzimba ngesikhathi senqubo yokuvuvukala nezifo ezithathelwanayo;
- ukuvimbela ukugoqwa kwegazi kanye ne-embolism, i-platelet liquefaction, imithambo ye-varicose, i-thrombosis;
- Ubuhlungu banoma yiluphi uhlobo lwezinsini: ukuya esikhathini, izinyo, ukukhanda ikhanda, izinhlungu ezihlukumezanayo, njll;
- ekuhlinzeni ngisebenzisa ikhambi lokujova ukudambisa imfiva nobuhlungu;
- i-inhliziyo ye-inhliziyo: i-ischemia, i-arrhythmias, ukuvimbela ukufakwa kwe-myocardial frequency, stroke, isifo seKawasaki, ukuhluleka kwenhliziyo.
Kungathathwa ithebhulethi eyodwa ukwehlisa izinga lokushisa noma kudambise i-pain pain syndrome. Kwi-pathologies engapheli, ekuvimbeleni noma ekwelashweni, i-acetylsalicylic acid idakwe ngenkambo udokotela ayinqumayo ngokuya nge-pathology.
Contraindication
Kunenombolo yokuphikisana lapho kwenqatshelwe ukuthatha i-ASA MS ukuze kungalimazi impilo yakho:
- hypersensitivity ezingxenyeni zokwakheka;
- "i-aspirin" nesifuba somoya;
- ukopha emathunjini kanye nokuba khona kwezifo ezingamahlalakhona ezingapheli noma ezinzima;
- i-encephalopathy ye-acute;
- Ama-trimesters we-1 no-3 wokukhulelwa, ku-2 kungenzeka kuphela njengoba kuyalelwe udokotela.
Awungeke usebenzise lesi sidakamizwa ezinganeni ezingaphansi kweminyaka engu-15 ngaphandle kokuyalelwa ngudokotela, ngoba ingane ingaba ne-Reye's syndrome (isifo esibonisa ukwehluleka kwesibindi okuqine).
Ungayithatha kanjani i-acetylsalicylic acid MS
Umuthi uthathwa ngaphambi kokudla futhi ugezwe ngamanani amaningi amanzi ahlanzekile. Ngomthamo owodwa, kusetshenziswa i-0.5 mg yesidakamizwa (i-1 ithebhulethi). Ukuphinda usebenzise kungasetjenziswa ngaphambi kwamahora ama-4. Umthamo wansuku zonke akufanele wedlule amaphilisi ayi-6.
Ekwelashweni okuyinkimbinkimbi kwezifo ezinzima noma ezingamahlalakhona, i-ASA ichazwe kumthamo we-1 mg umuthi (amaphilisi ama-2) kathathu ngosuku.
Isikhathi sokwelashwa asidluli kwezinsuku eziyi-7 ngokuthola ukwelashwa okujwayelekile futhi akukho ngaphezulu kwe-3 ngokuncipha kwezinga lokushisa. Lapho uthatha umuthi, kubalulekile ukuthi unake ukudla okunempilo.
Ngoshukela
Awukwazi ukusebenzisa izidakamizwa ngokuya nge-ASA.
Imiphumela emibi ye-Acetylsalicylic acid acid MS
Njenganoma yisiphi isidakamizwa, i-ASA ingadala imiphumela emibi eminingi uma kwenzeka kungabekezelelwa, ukuxhumana okungafanele, noma ukwephulwa komthamo.
Uma usebenzisa ama-NSAIDs, izilonda zingavela.
Kusuka ohlelweni lokuhlangana kwegazi
Engxenyeni yesistimu ye-hematopoietic, ukubalwa kweplatelet kungenzeka kukhubazeke, okuholela ekunciphiseni kwegazi ngokweqile. Ngenxa yalokhu, ukuphuma kwe-subcutaneous and yangaphakathi kwenzeka.
Amapheshana wesisu
Lapho usebenzisa ama-NSAIDs, ubungozi be-pathologies yesisu bukhuphuka. Izilonda, isifo sikaCrohn, ukopha kwangaphakathi, njll. Kungavela phakathi kwezimpawu zokungasebenzi kahle kohlelo lokugaya ukudla, isicanucanu, ukugabha, ukuphazamiseka kwesitulo, ukugabha isikhathi eside ngegazi kungabonakala.
Izitho zeHematopoietic
Imvamisa iziguli ziba ne-anemia - ukuntuleka kwe-hemoglobin, okuvela ngenxa yokuntuleka kwensimbi emzimbeni.
Isistimu yezinzwa ephakathi
Ubuhlungu bekhanda, i-tinnitus, ukungaboni kahle, ukulahleka kwezindlebe. Ukuphazamiseka kwemizwa noma ukuqothuka akuzange kubhalwe phansi.
Imvamisa iziguli ziba nezemizwa.
Kusuka ohlelweni lomchamo
Ukuthuthukiswa kokuhluleka kwe-renal, ukuchama kaningi, i-nephrotic syndrome, ukuvela kokuvuvukala okukhulu kwe-nephritis.
Allergies
Ukusabela komzimba kungavela ngenxa yokungabekezelelani ezingxenyeni zokwakheka noma ukuphathwa okungafanele komuthi. I-Pathology ibonakaliswa ukuqhuma kwesikhumba, ukulunywa. Kwezinye izimo, kuba nzima ukuphefumula maqondana nokuvuvukala kwe-pharynx.
Umthelela ekhonweni lokulawula izindlela
Akunamiphumela emibi ohlelweni lwezinzwa nokuhlushwa lapho uthatha umuthi, kepha kunconyelwa ukwenqaba ukulawula imoto uma kungenzeka ngenxa yemiphumela emibi ezithweni zombono nokuzwa.
Imiyalo ekhethekile
Ukuze ungalimazi impilo, ngaphambi kokusebenzisa umuthi, kufanele ufunde imiyalo futhi uzijwayeze nezincomo zomenzi wazo.
Kwezinye izimo, kuba nzima ukuphefumula maqondana nokuvuvukala kwe-pharynx.
Isabelo sezingane
Izingane ezingaphansi kweminyaka engu-15 azinqunyelwe amaphilisi e-ASA MS ngenxa yobungozi obukhulu bemiphumela emibi. Ukukhishwa kuyizimo ezimbi kakhulu zokushisa ngokweqile, lapho udokotela ejova khona i- "triad" (Aspirin, Analgin neNo-Shpu) ngokubhekela ukwehla kwezinga lokushisa okuphuthumayo. Akunazingozi. Ngokuqhubekayo, i-ASA inqatshelwe ngokuphelele ezinganeni.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Akunconyelwe ukuthatha umuthi ngesikhathi sokukhulelwa, ikakhulukazi ku-trimester yokuqala, lapho ingane isakha nje. Kwi-trimester yesibili, ungasebenzisa umuthi ngemithamo emincane, uma umphumela olindelekile udlula ubungozi obukhona. Ngoba umuthi ungeniswe ngokuphelele egazini nawo wonke amaseli omzimba, ngesikhathi sokuqunjelwa kuyingozi enkulu ukusithatha, ukuze singalimazi ingane.
Isicelo sokusebenza kokulimala kwezinso
Ngesikhathi sokuhluleka kwezinso, i-ASA ayisetshenziswanga ngenxa yokungakwazi ukususa imikhiqizo yokugcina. Ngenxa yalokhu, imetabolism iyaphazamiseka futhi umsebenzi cishe wazo zonke izitho nezinhlelo uyawohloka.
Ngesikhathi sokuhluleka kwezinso, i-ASA ayisetshenziswanga ngenxa yokungakwazi ukususa imikhiqizo yokugcina.
Sebenzisa umsebenzi wesibindi okhubazekile
Uma kwenzeka ukungasebenzi kahle kwesibindi, i-ASA ayinconywa. Ngokungapheli nokungapheli kwesifo sikaReye, izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala azivinjelwe.
I-overdose ye-Acetylsalicylic Acid MS
Ngokusetshenziswa ngokweqile kwesidakamizwa ku-plasma, ukugcwala kwama-salicylates kuyanda futhi ngenxa yalokhu, kuye kuvela izimpawu eziningana zokweqisa:
- Ubuthi obulinganiselayo bungabonakala ngokukhanda kakhulu kwekhanda, isiyezi, isicanucanu nokuhlanza. Kukhona futhi umuzwa wenjabulo nokwesaba.
- I-overdose enzima ibonakaliswa ukugabha isikhathi eside, ukuphefumula, izinhlungu ezinzima esiswini noma amathumbu, umkhuhlane, ukujuluka ngokweqile
- Nge-overdose engapheli ye-ASA MS, ukwehluleka kwezinso, izifo ezingamahlalakhona zepheshana lesisu, nokungasebenzi kahle kwesibindi kukhula.
Njengokwelashwa kwezinga eliphansi nelilinganiselwe, kwanele ukuhlanza isisu futhi uthathe namalahle ocushiwe. Ukuze uthole ubuthi obunamandla be-acetyl, ukulaliswa esibhedlela nokuhlolwa okugcwele kuyadingeka.
I-overdose enzima ibonakaliswa ngokuhlanza isikhathi eside.
Ukuxhumana nezinye izidakamizwa
I-Acetylsalicylic acid ayikwazi ukusetshenziswa namaqembu athile wezidakamizwa ngenxa yokuvela komphumela ongathandeki:
- lapho uthathwa ndawonye ne-thrombolytics, ubungozi bokuthi ukopha kwangaphakathi kukhuphuke;
- ayikwazi ukusetshenziswa ne-valproic acid, ngoba i-ASA yandisa ubuthi bayo;
- kwenyusa ukusebenza kwe-narcotic painkiller, ngakho-ke, ngaphambi kokuyithatha, kufanele uthintane nodokotela wakho;
- Ukusetshenziswa kanye kanye namanye ama-NSAIDs kukhulisa ubungozi bokukhula kwe-pathologies yesisu.
Lapho unquma lesi sidakamizwa, udinga ukwazisa udokotela ngokuthatha amanye ama-generics.
Ukuhambisana notshwala
Iziphuzo zotshwala ziqukethe i-ethanol, okuthi uma ihlangana ne-ASA ikhuphule ubungozi bokuphuma kwe-gastric, ukuthuthukiswa kwe-gastritis noma izilonda kanye nokugaya kokulimazeka.
Ama-Analog
Phakathi kwezidakamizwa zesenzo esifanayo, okulandelayo kungaphawulwa:
- I-Thrombo Ass;
- Aspirin Cardio;
- I-Cardiomagnyl.
Kubalulekile ukukhumbula ukuthi ukwelashwa ngaphandle kokubonana nochwepheshe kungaba yingozi empilweni, ngakho-ke kufanele uthintane nodokotela wakho ngaphambi kokushintsha umuthi wakho.
Imibandela yekhefu lekhemisi
Ungathenga ekhemisi ngalinye noma esitolo online ngaphandle kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Yebo
Intengo
Izindleko zomuthi zivela kuma-ruble angama-20.
Izimo zokugcina zomuthi
Endaweni emnyama endaweni yokushisa yasekamelweni, gcina kude nezingane.
Isikhathi sokuphelelwa yisikhathi
Impilo ye-Shelf - iminyaka emi-4 kusukela ngosuku okhiphe ngalo. Ngemuva kosuku lokuphelelwa yisikhathi, ungasebenzisi isidakamizwa.
Umkhiqizi
I-CJSC Medisorb, eRussia.
Ukubuyekezwa
UMarina Sergeevna, oneminyaka engama-48, u-Oryol
Sekuphele iminyaka eminingi ngithatha i-ASA ukuncipha kwegazi. ICardiomagnyl yayinqunyelwe ngaphambilini, kepha lapho ngifuna ama-analogue ashibhile, udokotela wangeluleka ukuba ngisebenzise isidakamizwa saseMedisorb. Ikhambi elihle kakhulu, ngilithatha ngokungatheni ngokusho komthamo, kwakungekho miphumela emibi.
U-Ivan Karlovich, oneminyaka engama-37, uYeysk
Kwi-arthrosis ehlangene, la mapilisi anqunywa. Angisho ukuthi yonke into yayeka ukulimala ngqo, kodwa izinhlungu zancipha isikhashana. I-ASA isiza kuphela ngokwelashwa okuyinkimbinkimbi.
