Isidakamizwa i-Siofor 1000 sinqunywa ama-endocrinologists kulezo ziguli ezitholakala zinesifo sikashukela esingadingi ukuthi kungeniswe i-insulin. Umuthi uvame ukusetshenziswa ekwelapheni isifo sikashukela, osisindo saso siphakeme kakhulu kunokwejwayelekile, futhi ukudla kanye nokuzivocavoca umzimba akuniki umphumela omuhle.
Igama Lezwe elingafanele
I-Metformin.
Isidakamizwa i-Siofor 1000 sinqunywa ama-endocrinologists kulezo ziguli ezitholakala zinesifo sikashukela esingadingi ukuthi kungeniswe i-insulin.
Ath
A10BA02.
Khipha amafomu nokwakheka
Ukuphela kwendlela umenzi anikezela ngayo umuthi ngamatafula aphekwe kahle. Umbala wabo umhlophe futhi isimo sabo sishwabene. Ngayinye inengozi - ngosizo lwayo, ithebhulethi ihlukaniswe izingxenye ezimbili ezifanayo: ngale ndlela kulula ukuyithatha. Kwithebhulethi kukhona ukudana okwenziwe ngesigaxa.
Ngenxa yokuba khona kwe-metformin hydrochloride, umuthi unomphumela wokwelapha. Lokhu kusebenza, ithebhulethi ngayinye iqukethe i-1000 mg. Yethula ekwakhiweni nasezakhiweni ezengeziwe ezithuthukisa umphumela wokwelapha.
Umenzi upakisha amaphilisi ezibhulweni - izingcezu eziyi-15 kwelilodwa. Ngemuva kwalokho amabhulashi afakwa emabhokisini amakhadibhodi - izingcezu ezi-2, ezi-4 noma ezi-8 (amaphilisi angama-30, angama-60 noma ayi-120). Kuleli fomu, uSiofor uya emakhemisi.
Isenzo se-Pharmacological
Umphumela oyinhloko wezidakamizwa ukwehlisa ushukela wegazi. Umuthi awuthinti ukwenziwa komzimba kwe-insulin, ngakho-ke ingozi yokuqhamuka ne-hypoglycemia incishiswa ibe ngu-zero.
Ngaphezu komphumela wesidakamizwa esilinganisweni se-glucose ku-plasma, ukuthatha amaphilisi kuthinta i-lipid metabolism: cholesterol iyancipha, futhi inani le-triglycerides liyancipha.
Isiguli esithatha umuthi sinokwehla kokudla. Abantu abakhuluphele bayayisebenzisa: baphuza amaphilisi ukwehlisa isisindo.
Isiguli esithatha umuthi sinokwehla kokudla.
I-Pharmacokinetics
ISiofor idinga isikhathi esincane sokutholwa ngumzimba - cishe amahora angama-2,5. Ngemuva kwenkathi yesikhathi enjalo, into esebenzayo ifinyelela ezingeni layo eliphezulu emzimbeni. Esigulini sithatha umuthi, ukugcwala kweplasma kwento esebenzayo kugcinwa ku-4 μg / ml.
Ukuphila kwesigamu umuthi kungamahora ayi-6.5. Kodwa le nkomba ibonakala ezigulini ezingazihluphi nge-pathologies yezinso. Uma umsebenzi wezinso ukhubazekile, khona-ke lesi sikhathi siyanda, ngenkathi ukugcwala kwento esebenzayo nakho kuyanda.
Izinkomba zokusetshenziswa
Umuthi unqunywa yi-endocrinologists kulezo ziguli ezitholakala zinesifo sikashukela sohlobo 2.
Umuthi ungaba yingxenye yokwelapha okuyinkimbinkimbi. Kusetshenziswa ndawonye ne-insulin nezidakamizwa ezivela eqenjini lama-hypoglycemic agents.
Contraindication
Umuthi kufanele uphuzwe ngokuqinile njengoba kuchazwe udokotela, ngoba kunenombolo enkulu ye-contraindication ukuze isetshenziswe. Phakathi kwazo kukhona:
- i-precoma - isimo ngaphambi komqondo wesifo sikashukela;
- umsebenzi wezinso ongonakalisiwe;
- izifo ezibangela ukuntuleka komoya-mpilo ezicutshini;
- uphuzo oludakayo;
- thayipha i-1 isifo sikashukela;
- ukungabekezelelani ngakunye kunoma iyiphi ingxenye ekhona ekwakhiweni kwamathebulethi.
Uma ulandela ukudla okuphansi kilojoule, akunconywa uSiofor.
Ngokunakekela
Umuthi lo usetshenziswa ngokuqapha ekwelapheni iziguli ezisukela eminyakeni eyi-10 kuye kweyi-12 neziguli ezingaphezulu kweminyaka engama-60.
Ungayithatha kanjani iSiofor 1000
Amathebulethi ayatholakala ukusetshenziswa komlomo (ukuphathwa ngomlomo). Gwema ukuthuthukiswa kwemiphumela emibi kuzosiza ukusetshenziswa komuthi ngokudla noma ngokushesha ngemuva kwesidlo sasekuseni, isidlo sasemini noma sakusihlwa. Ithebhulethi alihlafunwanga, kepha ukwenza inqubo yokugwinya ingahlukaniswa izingxenye ezimbili. Uma kunesidingo, umuthi ugezwa ngamanzi.
Okungakanani metformin okufanele kuthathwe kunqunywa yi-endocrinologist. Udokotela unaka izinkomba ezahlukahlukene, kufaka phakathi noshukela.
Ukwehla kwesisindo
Umuntu ofuna ukunciphisa umzimba kunconywa ukuthatha ithebhulethi eyi-1 ngosuku ekuqaleni kwezokwelapha. Kancane kancane shintshela ekuthatheni amaphilisi ama-2, bese kuba ngu-3. Kungcono ukuthi uwasebenzise ngemuva kwesidlo sakusihlwa. Uma kwenzeka ukukhuluphala kohlobo lwesisu, udokotela angayandisa umthamo.
Udokotela uzoncoma ukuthi inkambo yokwelashwa kufanele ithathe isikhathi esingakanani. Ngaphandle kweseluleko sochwepheshe, awukwazi ukusebenzisa umuthi.
Ngaphandle kweseluleko sochwepheshe, awukwazi ukusebenzisa umuthi.
Ukwelashwa kwesifo sikashukela
Iziguli zabantu abadala ekuqaleni kwezokwelapha zibekelwa ithebhulethi engu-1/2 ye-Siofor 1000, i.e. 500 mg yento esebenzayo. Ukwemukelwa kwenziwa izikhathi ezi-1 noma ezi-2 ngosuku ngezinsuku eziyi-10-15.
Lapho-ke umthamo ukhuphuka ube isilinganiso samathebhulethi ama-2 ngosuku, isb. 2000 mg. Uma kunesidingo, udokotela angabeka amaphilisi ama-3 - ucezu olu-3 izikhathi ngosuku. Ukwanda kancane kancane komthamo kuyadingeka ukuze kuncishiswe ubungozi bemiphumela emiphumeleni yezitho zomgudu wesisu.
Uma isiguli sithathe eminye imishanguzo yesifo sikashukela, kufanele sishiywe lapho siguqukela ekwelashweni noSiofor. Kepha uma isiguli sifaka imijovo ye-insulin, khona-ke ingahlanganiswa neSiofor.
Umthamo womuthi wezingane nowentsha uqokwa udokotela. Ukwelashwa kuqala ngomthamo omncane ngokwanda kancane kancane. Ubukhulu - 2000 mg ngosuku.
Imiphumela emibi
Umuthi uthathwa ngokuqinile njengoba kuchazwe udokotela, ngaphandle kwalokho ukuthuthukiswa kwemiphumela emibi engafuneki kungenzeka.
Amapheshana wesisu
Iziguli zikhononda nge-nausea, okuholela kokuhlanza, isifo sohudo nobuhlungu esiswini, isifiso esibi sokudla. Abanye abantu banambitha yensimbi emilonyeni yabo.
Kwezinye izimo, ngemuva kokudla umuthi, iziguli zikhononda nge-nausea, okufika ekuhlanzeni.
Izimpawu ezifanayo zimpawu ekuqaleni kwenkambo yokwelapha, kepha ngokuhamba kwesikhathi ziyadlula. Ukugwema isimo esingathandeki, kufanele uhlukanise umthamo wansuku zonke kumakhambi ama-2-3 futhi uthathe umuthi ngokudla noma ngemuva. Uma uqala ukuphuza umuthi ngethamo elincane, bese uwukhulisa kancane kancane, khona-ke umgudu wokugaya ukudla ngeke uwuphathe kabi umuthi.
Izitho zeHematopoietic
Imiyalo esetshenziswayo ayisho ukuthi umuthi unganikeza umphumela ovela ohlelweni lwe-hematopoietic.
Isistimu yezinzwa ephakathi
Kungenzeka kube nenkinga yokulala nalabo abathatha iphilisi.
Kusuka ohlelweni lwezinhliziyo
Imiyalo yesidakamizwa ayishongo lutho ngomthelela omubi wesidakamizwa ekusebenzeni kohlelo lwezinhliziyo.
Engxenyeni yesibindi ne-biliary
Ngesinye isikhathi, iziguli ezithatha iSiofor zikhononda ngezinkinga zesibindi ezivelayo: umsebenzi owengeziwe wama-enzyme wesibindi nokukhula kwe-hepatitis kungenzeka. Kepha lapho nje umuthi umisiwe, isitho siqala ukusebenza ngokujwayelekile.
Ngesinye isikhathi, iziguli ezithatha iSiofor zikhononda ngezinkinga zesibindi ezivelayo.
Allergies
Ukuqhaqha esikhumbeni, ubomvu, futhi ukulunywa akuvamile ukuvela.
Imiyalo ekhethekile
Ngesikhathi sokulashwa, ukuhlolwa kwelabhoratri okuboniswe isifo sikashukela sohlobo 2 kufanele kwenziwe njalo.
Ukwelapha kuhilela ukuzidla nokuzivocavoca nsuku zonke.
Kunezinye izincomo eziningi zeziguli ezithatha iSiofor.
Ukuhambisana notshwala
AmaSiofor notshwala awahambisani. Uma uphuza utshwala phakathi nesikhathi sokwelashwa, khona-ke i-lactic acidosis ingahle ikhule.
Umthelela ekhonweni lokulawula izindlela
Ukuphuza umuthi akukuphazamisi kabi ukushayela nokusebenza ngamasu ayinkimbinkimbi.
Ukuphuza umuthi akukuphazamisi kabi ukushayela nokusebenza ngamasu ayinkimbinkimbi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
ISiofor akufanele ithathwe abesifazane abakhulelwe.
Lapho uhlela ukukhulelwa, isiguli esiphuza lesi sidakamizwa kufanele sixwayise udokotela ukuthi uzoba ngumama. Udokotela uzomdlulisela ekwelashweni kwe-insulin. Kubalulekile ukukhulisa ukusondelana kwamazinga kashukela wegazi kumanani ajwayelekile ukuze uvikele ubungozi bokuthuthukisa ama-pathologies e-fetus.
I-Metformin idlulela kubisi lwebele. Lokhu kuboniswe ngokuhlolwa ezilwaneni zaselabhoratri.
Kuyadingeka ukwenqaba ukuthatha uSiofor ngesikhathi sokuqunjelwa noma ukuyeka ukuncelisa ibele.
Ukuqokwa kweSiofor ezinganeni ezi-1000
Ekwelashweni kwezingane ezingaphansi kweminyaka eyi-10, umuthi awusetshenziswa. Ezigulini ezisukela eminyakeni eyi-10 kuye kweyi-12 ubudala, udokotela angabeka uSiofor uma ingane inesifo sikashukela, kepha kumele usebenzise umuthi ngaphansi kweso elibukhali udokotela.
Sebenzisa ebudaleni
Abantu abafinyelele eminyakeni engama-60 yobudala futhi benza umsebenzi onzima womzimba, amaphilisi angathathwa, kodwa ngokuqapha - ngaphansi kokuqondisa udokotela. Mhlawumbe ukuthuthukiswa kwe-lactocytosis.
Abantu abafinyelele eminyakeni engama-60 yobudala futhi benza umsebenzi onzima womzimba, amaphilisi angathathwa, kodwa ngokuqapha - ngaphansi kokuqondisa udokotela.
Isicelo sokusebenza kokulimala kwezinso
Udokotela ngeke anikeze umuthi isiguli esihlushwa yizinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukwehluleka kwe-Hepatic ukwephula amaphilisi.
Ukweqisa
Uma umthamo obekwe udokotela ungabhekwa, ukuthuthukiswa kwe-lactic acidosis kungenzeka, kube nezimpawu ezilandelayo:
- ubuthakathaka
- ukozela
- dyspepsia
- i-hypothermia;
- ukulahlekelwa ukwazi.
Uma umthamo ungabhekwa, ukozela kungenzeka.
Uma lesi simo senzeka, funa usizo lodokotela. Esibhedlela, isiguli sizothola i-hemodialysis.
Ukuxhumana nezinye izidakamizwa
Uma udokotela enquma uSiofor, isiguli kufanele simazise ngemishanguzo ayiphuzayo. Lokhu kusebenza nakwimikhiqizo engaphezulu kwe-counter.
Inhlanganisela ehlanganisiwe
Ngaphambi kwe-X-ray, okubandakanya ukwethulwa kwezidakamizwa eziqukethe i-iodine njengomehluko, yeka ukuthatha uSiofor ezinsukwini ezi-2 ngaphambi kosuku lapho isifundo sihlelelwe. Ngemuva kokuba inqubo isiqediwe, amaphilisi avunyelwe ukuphuza kuphela ngemuva kwamahora angama-48.
Akuhlanganisiwe ukuhlanganisa
Ukwelapha nge-Siofor kuhilela ukwenqaba okuphelele hhayi nje kotshwala, kodwa nemithi equkethe i-ethanol.
Ukwelapha nge-Siofor kuhilela ukwenqaba okuphelele hhayi nje kotshwala, kodwa nemithi equkethe i-ethanol.
Inhlanganisela edinga ukuqashelwa
Imiphumela engathandeki ingabangelwa ukusetshenziswa kanyekanye kweSiofor ngemithi elandelayo:
- nge-danazol - ngenxa yomphumela we-hyperglycemic;
- ngezindlela zokuvimbela inzalo ezithathwe ngomlomo, i-nicotinic acid, i-epinephrine - ngenxa yokwanda kwezinga likashukela;
- nge-nifedipine - ngenxa yokwanda kwesikhathi sokuhoxa kwengxenye esebenzayo;
- ngezidakamizwa ze-cationic - ngenxa yokwanda kokuhlushwa egazini lento esebenzayo eyingxenye yomuthi;
- nge-cimetidine - ngenxa yokuncipha kokukhishwa kwomuthi emzimbeni;
- ngama-anticoagulants - umphumela wabo wokwelapha uyancishiswa;
- nge-glucocorticoids, i-ACE inhibitors - ngenxa yezinguquko enanini le-glucose egazini;
- nge-sulfonylurea, i-insulin, i-acarbose - ngenxa yokwenyuka kwemiphumela ye-hypoglycemic.
Ama-Analog
Umphumela ofanayo ukhishwa yiMetformin neMetformin-Teva, iGlucofage ne-Glucofage ende.
I-Glucophage ende i-analogue yomuthi.
Izimo zeholide Siofora 1000 kusuka kumakhemisi
Ngaphambi kokuthenga umuthi, kufanele ubonane nodokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
ISiofor umuthi onikezwa kadokotela.
Intengo
Izindleko zanoma yimuphi umuthi zincike endaweni ethengiswayo. Izindleko eziphakathi kwe-Siofor 1000 zisuka kuma-ruble angama-360 kuye kwangama-460.
Izimo zokugcina zomuthi
Ekamelweni lapho kugcinwa khona umuthi, izinga lokushisa komoya akufanele lidlule + 30 ° C.
Ekamelweni lapho kugcinwa khona umuthi, izinga lokushisa komoya akufanele lidlule + 30 ° C.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi uSiofora 1000
Inkampani yaseGerman "Berlin-Chemie AG".
Ukubuyekezwa kwe-Siofor 1000
Cishe konke ukubuyekezwa ngokusetshenziswa kwezidakamizwa kulungile.
Odokotela
UTatyana Zhukova, oneminyaka engama-39, uTomsk: "Ezokwelapha, ngivame ukunikela iSiofor emithanjeni ehlukahlukene yesifo sikashukela esikhuluphele. Umuthi lo ubujwayeza i-carbohydrate metabolism futhi unomthelela ekunciphiseni isisindo uma isiguli silandela ukudla okunekhalori eliphansi."
U-Alla Barnikova, oneminyaka engama-45, u-Yaroslavl: "ISiofor ilula ukuyisebenzisa, isebenza kahle, ibekezelelwa kahle yiziguli. Ngibeka ukungahambisani ne-insulin, uhlobo lwesifo sikashukela. Umuthi unentengo efinyelelekayo."
Iziguli
USvetlana Pershina, oneminyaka engama-31, uRostov-on-Don: "Udokotela ubeke uSiofor ngenxa yokwanda kwe-insulin. Ngithatha amasonto ama-3. Kuqale kwaba nemiphumela emibi eminingi - ukusuka ku-nausea nekhanda kuya kubuhlungu besisu nobuhlungu besisu. Kepha kancane kancane konke kwahamba. Ukudla sekunciphise kakhulu, kepha angizizwa njengokudla ukudla okumnandi nokunesitashi. Ukuhlaziywa kwakamuva kukhombise ukwehla okuncane kwe-insulin.
UKonstantin Spiridonov, oneminyaka engama-29 ubudala, uBryansk: "I-endocrinologist inqume uSiofor ngenxa yesifo sikashukela, ethi udinga ukunamathela ekudleni okunekhalori eliphansi. Bengilokhu ngikuthatha izinyanga eziyisithupha. Ngaphandle kokunciphisa amazinga kashukela, ngilahlekelwe ngama-8 kg."
