I-Gemfibrozil: ukubuyekezwa kwezidakamizwa, izinkomba kanye nemiyalo

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Ngenxa yezinkinga zenhliziyo nemithambo yegazi, ingxenye enkulu yabantu emhlabeni iyahlupheka. Lesi sizathu singumholi emacaleni abulalayo. Yize i-cholesterol ibalulekile emzimbeni, izinga layo eliphakeme lingesinye sezizathu ezibalulekile zokuthuthukiswa kwesifo senhliziyo. Imvamisa lokhu kwehla kwenzeka kubantu besigaba 40+, ababhemayo abangakunaki ukudla okunempilo. Uma kutholakala i-pathology, isiguli sinqunywe izindlela zokwelapha.

Uma lesi sifo sitholakala ekuqaleni, ukwelashwa kusatshalaliswa nezidakamizwa, futhi uma umzimba unqotshwa i-cholesterol ende isikhathi eside, izidakamizwa ezisehlisa i-lipid zibekelwe isiguli. Enye ye-ejenti enjalo yi-gemfibrozil.

Ukukhishwa kwalesi sidakamizwa kwenzeka eRussia naseNetherlands, ngesimo samathebulethi. Thatha lihlanganiswe nezinye izindlela zokwelapha. Kuhlanganisa ukudla okhethekile nokulandela indlela yokuphila enempilo. Ithuluzi elisebenzayo futhi ngesikhathi esifushane lifiphalisa izinga lama-lipoprotein egazini.

Ukuzelapha ngokwako akunconywa. Ukwazi ubuhle nobubi bomuthi, udinga ukufunda kabanzi ngezindlela zesenzo, izinkomba kanye ne-contraindication, isikhathi somphumela.

Umuthi uhlukaniswa njengezidakamizwa ezokwehlisa i-lipid. Yakhiwa ngososayensi ngenxa yomzamo wokuthola ama-analoges angama-clofibrate. Benze lokhu ngenhloso yokunciphisa ubuthi nobudlova bomuthi. Umphumela wayo uhlose ukucindezela inani le-cholesterol "embi" ne-triglycerides, okwandisa i-cholesterol enempilo. Wenza ukukhishwa kwe-cholesterol ngesibindi.

Umuthi unconywa ukuthi usetshenziswe ezimweni:

  1. I-hyperlipoproteinemia eyisisekelo yezinhlobo 2, 5, 4, engalungiswa ngokondleka nemithwalo.
  2. I-Hypertriglyceridemia (izinga eliphakeme lama-triglycerides egazini), esimweni sokungasebenzi kahle kokudla nezinye izidakamizwa.
  3. I-Hyperlipoproteinemia yesibili ephakama ngemuva kwesifo se-gout, isifo sikashukela, i-hypothyroidism.

Ngaphezu kwezinkomba, umuthi unemikhawulo yawo ekusetshenzisweni. Uma umuntu enento okungenani eyodwa ohlwini, umuthi kufanele ulahlwe. Ukuba khona kobufakazi kufanele kunqunywe ngudokotela. Contraindication ifaka ukungasebenzi kahle kwe-renal kanye ne-hepatic; ukukhulelwa nokuqunjelwa; umsebenzi ophakeme wama-transaminases wesibindi; okuncane; ukungabekezelelani komuntu ngamunye kwizakhi; ukuqina kwesibindi.

Akunconywa nokuthi uthathe imishanguzo kubantu abalimele isibindi sotshwala ngemuva kokuhlinzwa kwe-organ transplant. Kwezinye izimo, kumele kuthathwe ngokuqapha. Noma yikuphi ukusetshenziswa kufanele kuvunyelwane nodokotela. Ukuvinjwa okuhlobene kufaka phakathi:

  • ukwehluleka kwesibindi;
  • ukwehluleka okungapheli kwezinso esigabeni esinzima;
  • cholelithiasis;
  • cholecystitis engapheli;
  • i-hypertriglyceridemia;
  • uphuzo oludakayo;
  • ngokuhambisana nokwelashwa kwe-immunosuppressive;
  • ukuvuselelwa ngemuva kokuhlinzwa.

Akunconywa ukuthatha umuthi uwedwa, ngoba uchwepheshe kuphela onganquma ukuba khona kwezinkomba. Udinga ukugcina amatafula endaweni eyomile, ngokushisa okuncane nomswakama. Kungcono ukuthi izingane zingabi nokufinyelela kuleyo ndawo.

Kuyenqatshelwa ukwamukela ngemuva kosuku lokuphelelwa yisikhathi.

Umuthi i-Gemfibrozil unemiyalo yokusebenzisa, intengo efanelekile nokubuyekezwa okuhle.

Umuthi kumakhemisi ungatholakala ngesimo samathebulethi, izingcezu ezingama-30 kwiphakeji ngalinye. Isithako esikhulu esisebenzayo yi-gemfibrozil.

Kufanele zithathwe imizuzu engamashumi amathathu ngaphambi kokudla, kabili ngosuku. Udinga ukuphuza amaphilisi amabili, uwahlukanise kube yimithamo emibili futhi uphuze amanzi amaningi, ngaphandle kokuhlafuna. Ukuze usebenzise ekuseni nakusihlwa.

Isikhathi sokwelashwa okunjalo sizoncika esimweni sesiguli kanye nezimpawu zomuntu ngamunye. Ngokuyinhloko, inkambo yokuphuza umuthi izinyanga ezintathu. Ngemuva kwayo, udinga ukuthatha ikhefu bese uphinda uma kunesidingo.

Kakade ngosuku lwe-5, umphumela wokuthatha umuthi uqala ukuvela, futhi umphumela omkhulu uwe ngosuku lwe-20-30 lokwelashwa. Ezinye iziguli zidinga ukwehlisa umthamo, ngakho-ke udokotela wehlisela inani lamaphilisi eyodwa nesigamu, athathwa kusihlwa ngesikhathi. Akunakwenzeka ukwandisa inani lomuthi, noma ngabe isiguli siphuthelwa umthamo ngesikhathi esifanele.

Kukhona amanothi omuthi okumele alandelwe:

  1. Ngesikhathi sokulashwa, isiguli sinconywa ukuba sihlole igazi (INA) njalo emavikini amathathu. Ngosizo lokuhlolwa, uchwepheshe uqapha okuqukethwe kwama-lipids egazini lesiguli.
  2. Uma ngesikhathi sokuphathwa kobuhlungu bemisipha, udinga ukubona udokotela ukuthi akhiphe i-myositis. Uma ukutholwa kuqinisekisiwe, ukunqanyulwa komuthi kuyadingeka.
  3. Ngesikhathi sokwelashwa, kufanele unamathele kumenyu ekhethekile esiza ukunciphisa izinga le-cholesterol embi egazini.
  4. Uma isiguli sephula isibindi, kufanele uhlaziye izinkomba zalo mzimba ngaso sonke isikhathi.

Lesi sidakamizwa sinemiphumela emibi. Noma yikuphi ukubonakaliswa ngesikhathi sokuvuma kufanele kube yisizathu sokuxhumana nesikhungo sezokwelapha. Uma kungenzeka, udinga ukuwuyeka umuthi.

Umphumela wecala ubonakala ngendlela yokuthi:

  • izinhlungu zamathumbu;
  • ukuphazamiseka kwesitulo;
  • ukuthopha;
  • isifiso sokucindezela;
  • ukushisa kwenhliziyo;
  • ikhanda;
  • Isiyezi
  • ukwehluleka
  • ukozela
  • ukunganaki;
  • Ukudana
  • i-myalgia;
  • i-arthralgia;
  • ukungasebenzi ngocansi;
  • ukungaboni kahle kwesikhashana (isithombe esifiphele, isithombe mnyama);
  • i-alopecia.

Ungasithenga lesi sidakamizwa kunoma yiliphi ikhemisi, ngaphandle kadokotela.

Intengo yesidakamizwa eRussia isuka kuma-ruble ayi-1600.

Umuthi awunazimpawu eziqondile.

Kumakhemisi, ungathola amathuluzi anendlela yokwenza efanayo nomphumela ofanayo.

Umuthi kufanele unqunywe ngudokotela, ngoba unesisekelo esehlukile nezakhi.

Inamagama angaphezu kwelilodwa okufakwa esikhundleni.

Analogs ifaka:

  1. I-Lipantil iyi-analog yakwamanye amazwe etholakala ekwelapheni i-cholesterol ephezulu. Umkhiqizi - eFrance. Amathebulethi e-cholesterol enziwe ku-fibroid acid, kanti isithako esikhulu esisebenzayo yi-fenofibrate. Izindleko zalo muthi zivela kuma-ruble angama-800. Kukhona nesidakamizwa esifanayo esinegama elifanayo ne-prefix 200.
  2. I-Omacor yi-ejenti yemvelo ehlisa i-lipid, okuyisisekelo sayo yi-Omega 3 - acid polyunsaturated. Basiza ukwehlisa i-cholesterol futhi bavikele ukwakheka kwe-plaque. Umenzi walo muthi yiJalimane. Kungabekwa nezindlela zokuvimbela ukulwa nokuhlaselwa yisifo senhliziyo, unhlangothi. Izindleko zomuthi zivela kuma-ruble ayi-1600.

Ngaphezu kwalokho, i-analogue yi-Roxer yezidakamizwa, enesakhi esiyinhloko - i-rosuvastatin. Ukukhishwa ifomu - amaphilisi. Izingcezu ezingama-30 nezingama-90 zithengiswa emaphaketheni. Kubekelwe ukuphazamiseka kwe-lipid metabolism. Ezigulini ezisengozini, kubekwa njenge-prophylactic yezifo zenhliziyo nezemithambo. Izindleko zalo muthi zivela kuma-ruble angama-800.

Ungayelapha kanjani i-atherosclerosis izotshela uchwepheshe kule vidiyo ekulesi sihloko.

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