UKUHLOLWA KWEGAZI KWE-PROTHROMBIN NE-FIBRINOGEN - UKULAWULWA KWESIFO SIKASHUKELA

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Igazi lomuntu liqukethe izinto eziningi ukwahlulela isimo somzimba. Kunesethi yokuhlolwa kwelebhu okubonisa isilinganiso sokujwayelekile noma ukuphambuka kwesikhombisi esithile.

Enye yezinkomba ezibaluleke kakhulu ezidinga ukuhlolwa njalo kwesifo sikashukela ukugcwala kwegazi.

I-coagulation yegazi yisinkomba esibhekele ukulawula izinga lokopha. Uma kwenzeka ukulimala kwemithambo, izinto ezakha igazi zakha izingqimba zegazi ezivimba ukulahleka kwegazi okuqhubekayo. Ngokuhlangana okujwayelekile ngemuva kwemizuzu eyi-10. ngemuva kokulimala okuncane esitsheni, amafomu wegazi.

Uma inqubo yokwakheka kwe-clot iqala ngokushesha okukhulu, khona-ke lokhu kungakhombisa ukukhuphuka kwegazi okwandisiwe - i-thrombophilia. I-Thrombophilia yisifo segazi esiholela ekwakhekeni kwezinqe zegazi kanye nokuqhekeka emithanjeni yegazi kanye nama-capillaries, okuholela ekuntulekeni kwe-oksijini kwezicubu zomzimba nezitho zomzimba, okubangela ukushaya kwenhliziyo, unhlangothi, imithambo ye-varicose, i-thrombosis nezifo zezitho zangaphakathi.

Izinto ezilawula izinga le-coagulation yegazi yi-prothrombin ne-fibrinogen.

I-Prothrombin

I-Prothrombin yiprotheni ebalulekile ye-plasma, ekhombisa izinga lokuqina kwegazi. Ithinta izinga lokwakheka kwegazi futhi yandulela i- thrombin, iprotheni ekhuthaza ukwakheka kwejazi legazi.

IProthrombin ikhiqizwa nge-Vitamin K esibindini. Usebenzisa inkomba yenkomba ye-prothrombin, ungalinganisa umsebenzi wesibindi kanye nethambo lesisu.

Lapho sihlaziya, izinkomba ezilandelayo ziyatholakala:

Isikhathi se-Prothrombin siyisinkomba esibonisa izinga lokujiya kwegazi, empeleni sibonisa izinga lokuqina kwe-prothrombin egazini. Umphumela ukhonjiswe ngemizuzwana. Norm 9-13 sec;
I-Prothrombin ngokusho kwe-Quick yisibonakaliso esibonisa umsebenzi we-prothrombin, esivezwe njengephesenti, esisungulwe sisebenzisa igrafu yokulinganisa ngokusekelwe kokushintsha kwesikhathi se-prothrombin kuzixazululo ezijwayelekile ze-plasma. Ukujwayelekile, ngokuya ngemishini esetshenzisiwe, kungu-77-120% .;
Inkomba ye-Prothrombin - inqunywa yisilinganiso sesikhathi se-prothrombin, isimilo somuntu onempilo kuze kufike isikhathi somuntu ongahlelekile wegazi. Norm - 80-110%;
Inkomba ye-INR iyinkomba esetshenziselwa ukuhlola ukusebenza kahle kokwelashwa ngezidakamizwa okuhloswe ngazo ukuvimbela ukuchitheka kwegazi. Ebantwini abaphilile, inkomba isebangeni le-80-115%.

Inqubo yokuhlaziya

Ngaphambi kokuthatha igazi ukuze lihlaziywe, udokotela kufanele azi ngezidakamizwa eziphuzwa yisifo sikashukela. Uma kunezidakamizwa ezingathinta imiphumela yocwaningo, zikhanselwa okwesikhashana.

Kulolu cwaningo, awudingi ukulandela ukudla okuyisipesheli noma ukulandela indlela yokudla (ngaphandle kokudla kanye nohlobo oludingekayo lwesifo sikashukela).

Ukubhobozwa kwegazi kwenziwa kusuka emithanjeni engalweni, emva kwalokho indawo yomjovo icindezelwa ngebhola likotini kuze kube yilapho ukopha kuyeka. Uma kuqhume inxeba endaweni yokubhoboza, kunikezwa izinqubo zokufudumeza.

Ukuphambuka kusuka kokujwayelekile

Izinga elikhulayo lesikhathi se-prothrombin (ngaphezu kwemizuzwana eyi-13) libonisa ukuthi kungenzeka i-thrombophilia ngenxa ye-vithamini K ethe xaxa (funda kabanzi ngamavithamini anyibilikayo, afaka no-Vitamin K kule ndatshana). Kubantu abanesifo sikashukela, isilinganiso siphezulu kakhulu, ngakho-ke kubalulekile ukuthi bahlaziye ngezikhathi ezithile ukuthola ukuthi ukuphambuka kangakanani.

Inani lesikhathi se-prothrombin siphambuke kokujwayelekile siye ohlangothini oluncane (ngaphansi kwemizuzwana engu-9) kungahle kwehle ngokuncipha kokuqina kwegazi, okubonisa ukuntuleka kwe-Vitamin K noma ukufakwa kabi kwe-vithamini emathunjini ngenxa ye-dysbiosis ne-enterocolitis.

Izici eziningi zingasebenza ukuthola umphumela ongalungile wokuhlaziya we-prothrombin:

Ukusetshenziswa kabi kotshwala;
Ukubhujiswa kwamangqamuzana abomvu egazi ngenxa yokuphatha ngokungakhathali kwe-tube yokuhlola enezinto ezibonakalayo;
Isampula yegazi leCapillary.

I-Fibrinogen

I-Fibrinogen yiprotheni ekhombisa izinga lokubonakala kwegazi, elenzelwe esibindini futhi libandakanyeka ekwakhekeni kwezicucu zegazi.

Izinga le-fibrinogen emzimbeni onempilo lingama-2-4 amagremu ngelitha ngalinye legazi.

Inqubo yokuhlaziya kanye nokungajwayelekile

Izidingo zokukhishwa ziyafana nalapho uthatha ukuhlaziywa kwe-prothrombin. Isimo esisodwa esibalulekile - ukuthuthwa kwegazi elabhoratri kufanele kwenziwe ekushiseni kwe +2 ̊С kuya ku -88 ̊С.

Ukwanda kwesilinganiso se-fibrinogen kungakhombisa izifo zezinso, izifo ezithathelwanayo, isimila somdlavuza, nokuqunjelwa kwe-myocardial.
Ukwehla kungenxa yesifo sesibindi, i-leukemia, umdlavuza wendlala, umdlavuza womongo.

Ukuthatha kangaki?

Ukunikela ngegazi ekunqumeni kokuhlangana kanye nokubona kufanele kwenziwe okungenani kanye ezinyangeni eziyisithupha, futhi lapho kunqunywa izidakamizwa, kwehlisa ukuqina kanye ngenyanga kuze kutholakale amanani ajwayelekile.

Kubalulekile ukuthi abantu abanesifo sikashukela banikele ngezikhathi ezithile ngegazi le-prothrombin ne-fibrinogen. Abantu abanesifo sikashukela, ngenxa yokuqukethwe kwabo okunoshukela omningi, basengozini ephindwe kabili yokuqhekeka kwegazi ngenxa yobuningi bamaprotheni abhekene ne-platelet liquefaction.

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