I-atherossteosis yisifo esivame kakhulu ngalesi sikhathi. Kubonakala ngokuqongelela kwe-cholesterol, noma kunalokho, i-cholesterol, emzimbeni womuntu, futhi ikakhulukazi emikhunjini yayo.
Emithanjeni yeziguli ezine-atherossteosis, kufakwa i-cholesterol plaque, okukhawulela ukuhamba kwegazi okujwayelekile futhi kungaholela emiphumeleni ebuhlungu njengokuqunjelwa kwe-myocardial kanye nesifo sohlangothi. I-Atherossteosis ithinta cishe ama-85-90% wabantu bomhlaba, ngoba inani elikhulu kakhulu lezinto ezahlukahlukene lifaka isandla ekuthuthukiseni kwalesi sifo. Yini okufanele yenziwe ukwelashwa kanye nokuvimbela lesi sifo?
Ukwelashwa kwezidakamizwa ze-atherossteosis nezinye izifo ezithile ze-metabolic, amaqembu anjalo wezidakamizwa asetshenziswa njengama-statins (Lovastatin, Atorvastatin, Rosuvastatin), i-fibrate (Fenofibrate), i-anion-exchange sequestrants, amalungiselelo aqukethe i-nicotinic acid nezinto ezinjenge-Vitamin (Lipoic acid).
Ake sixoxe kabanzi ngezidakamizwa ezinjengevithamini esibonelweni se-lipoic acid.
Indlela yokusebenza kanye nemiphumela ye-lipoic acid
I-Lipoic acid, noma i-alpha lipoic, noma i-thioctic iyisizinda esisebenza ngokuphila.
I-Lipoic acid ingeqembu lezinto ezihlanganiswayo eziyizinto ezinjengevithamini.
I-Acid isetshenziswa kwezokwelapha ukwelapha izifo eziningi.
Ukubaluleka kwaso kwemvelo kungokulandelayo:
- I-lipoic acid yi-cofactor - into engeyona iprotein, okuyingxenye ebalulekile yanoma iyiphi i-enzyme;
- abathinteka ngqo ohlelweni lwe-anaerobic (olwenzeka ngaphandle kokuba khona komoya-mpilo) i-glycolysis - ukuwohloka kwamangqamuzana eglue kuya ku-pyruvic acid, noma, njengoba kubizwa ngamafuphi, i-pyruvate;
- kunika amandla umphumela wamavithamini we-B futhi uwafake - ubamba iqhaza ekudla kwamafutha kanye nama-carbohydrate, asiza ukwandisa inani nokugcinwa kwe-glycogen esibindini, kunciphisa ushukela wegazi;
- kunciphisa ukudakwa komzimba wanoma imuphi umsuka, kunciphisa umphumela we-pathogenic wobuthi kwizitho nezicubu;
- kungokwesigaba sama-antioxidants ngenxa yekhono lokubopha ama-radicals mahhala anobuthi emzimbeni wethu;
- kahle nangokuvikelwa kuthinta isibindi (umphumela we-hepatoprotective);
- kwehlisa i-cholesterol yegazi (umphumela we-hypocholesterolemic);
- ingezwe kuzixazululo ezahlukahlukene ezenzelwe umjovo, ukunciphisa amathuba okuphendula okungahambi kahle.
Elinye lamagama e-lipoic acid yi-vithamini N. Ingatholakala hhayi ngemithi kuphela, kepha futhi nsuku zonke ngokudla. IVithamini N itholakala ekudleni okufana nobhanana, inyama yenkomo, u-anyanisi, ilayisi, amaqanda, iklabishi, amakhowe, imikhiqizo yobisi nemifino. Njengoba imikhiqizo enjalo ifakiwe ekudleni cishe komuntu wonke, ukuntuleka kwe-lipoic acid akunakwenzeka njalo. Kepha noma kunjalo iyakhula. Futhi ngokuntuleka kwe-alpha-lipoic acid, ukubonakaliswa okulandelayo kungabonakala:
- Isiyezi, izinhlungu ekhanda, kanye nezinzwa, okubonisa ukukhula kwesifo sezinzwa.
- Ukuphazamiseka kwesibindi, okungaholela ekuwohlokeni kwamafutha ayo nokungalingani ekwakhekeni kwe-bile.
- Ukufakwa kwemali kwama-atherosselotic plaque ezindongeni zemithambo yegazi.
- Ukushintshwa kokulinganisela kwe-acid-base ohlangothini lwe-acid, ngenxa yalokho okuvela kuyo i-metabolic acidosis.
- Ukuzenzakalela kwemisipha ye-spasmane.
- I-Myocardial dystrophy ukwephula umsoco nokusebenza kwemisipha yenhliziyo.
Kanye nokushoda, ukuvela ngokweqile kwe-lipoic acid emzimbeni womuntu kungenzeka. Lokhu kuboniswa yizimpawu ezinjengokuthi:
- ukushisa kwenhliziyo;
- i-hyperacid gastritis ngenxa yomthelela onolaka we-hydrochloric acid yesisu;
- ubuhlungu esifundeni se-epigastrium nesifunda se-epigastric;
Ngaphezu kwalokho, ukungezwani komzimba kwanoma yiluphi uhlobo kungavela esikhunjeni.
Izinkomba kanye ne-contraindication zokusetshenziswa kwamalungiselelo e-lipoic acid
I-Alpha lipoic acid iyatholakala ngezindlela ezahlukahlukene zomthamo. Okuvame kakhulu yizixazululo zamathebulethi nawomjovo kuma-ampoules.
Ithebhulethi inomthamo ongu-12,5 kuya ku-600 mg.
Ziphuzi ngombala okhethekile. Futhi ama-ampoules omjovo aqukethe isixazululo sokuhlushwa ngamaphesenti amathathu.
Umuthi uyingxenye yezithako eziningi zokudla ngaphansi kwegama thioctic acid.
Noma yiziphi izidakamizwa eziqukethe i-lipoic acid zibekwa ngokuya ngezinkomba ezilandelayo:
- I-Atherossteosis, ethinta ikakhulukazi imithambo yegazi.
- Izinqubo zokuvuvukala zesibindi ezibangelwa amagciwane, futhi zihambisana ne-jaundice.
- Ukuvuvukala okungapheli kwesibindi esigabeni esibuhlungu.
- Ukulimala kwe-lipid metabolism emzimbeni.
- Ukwehluleka kwesibindi okusebenzayo.
- Ukonakala kwamafutha kwesibindi.
- Noma ikuphi ukudakwa okubangelwa izidakamizwa, ama-alkoholi, ukusetshenziswa kwamakhowe, izinsimbi ezisindayo.
- Inqubo engapheli yokuvuvukala kumanyikwe ebangelwa ukuphuza ngokweqile.
- I-neuropathy yesifo sikashukela.
- Ukuhlanganiswa okuhlanganisiwe kwe-gallbladder kanye namanyikwe ngendlela engapheli.
- I-Cirrhosis yesibindi (ukufakwa ngokuphelele kwe-parenchyma yayo ngezicubu ezihlangene).
- Ukwelashwa okugcwele ukwenza lula inqubo yezinqubo ze-oncological ngezigaba ezingenakuphikwa.
Ukuxhumanisa ukusetshenziswa kwezidakamizwa eziqukethe i-lipoic acid kungokulandelayo:
- noma yiziphi izibonakaliso zangaphambili zalesi sifo;
- ukukhulelwa nokuqunjelwa;
- iminyaka engu-16.
Futhi, yonke le mishanguzo inemiphumela emibi:
- Ukubonakaliswa kwe-allergic.
- Ubuhlungu esiswini esingenhla.
- Ukwehla okukhulu ushukela wegazi, okuyingozi kakhulu kwabanesifo sikashukela;
- Ephindeka emehlweni.
- Ukuphefumula okuphefumulelwe.
- Imivimbo ehlukahlukene yesikhumba.
- Ukuphazamiseka kwemikhuba, kuboniswe ngendlela yokopha.
- Migraines
- Ukuqhephuka nezinzwa.
- Izibonakaliso ezivusa inkanuko.
- Khuphula umfutho we-intracranial.
Ngaphezu kwalokho, ukubonakala kokungena kwamathambo esikhunjeni nolwelwesi lwama-mucous.
Imiyalo yokusebenzisa umuthi
I-Lipoic acid kufanele ithathwe ngokucophelela, ngokusekelwe kuphela ekubhalweni kadokotela wakho. Inani lokutholwa phakathi kwemini linqunywa umthamo wokuqala womuthi. Isilinganiso esiphezulu se-thioctic acid ngosuku, ephephile futhi eyamukelekayo, singama-600 mg. Uhlobo lwangempela olujwayelekile lufika kane ngosuku.
Kudliwa amaphilisi ngaphambi kokudla, kugezwe ngenani lamanzi maningi, ngaphandle kokuhlafuna. Ngezifo zesibindi esigabeni esibuhlungu, i-50 mg ye-lipoic acid kufanele ithathwe kane ngosuku ngenyanga eyodwa.
Okulandelayo, udinga ukuthatha ikhefu, isikhathi udokotela azonquma ngaso. Futhi, njengoba kushiwo ngaphambili, ngaphezu kwamafomu wethebhulethi, lawo umjovo nawo ayatholakala. I-Lipoic acid iphathwa ngaphakathi kwezifo ezinamandla futhi ezinzima. Ngemuva kwalokhu, iziguli zivame ukudluliselwa ekusetshenzisweni kwamathebhulethi, kepha ngesilinganiso esifanayo njengoba kwenziwa imijovo - okungukuthi ukusuka kuma-300 kuye kuma-600 mg ngosuku.
Noma yiziphi izidakamizwa eziqukethe i-lipoic acid zidluliselwa ngomuthi kuphela, ngoba zisho umsebenzi futhi zingahlanganiswa nezinye izidakamizwa.
Ukulungiselela nganoma iyiphi indlela yokukhululwa (amaphilisi noma ama-ampoules) kufanele kugcinwe endaweni eyomile, emnyama futhi epholile.
Ngokusebenzisa ngokweqile i-Vitamin N, izimpawu zokweqisa zingase zivele:
- ukubonakaliswa komzimba, kufaka phakathi i-anaphylaxis (ukusabela okunamandla komzimba);
- izinhlungu zokudonsa kanye nokudonsa kwemizwa epigastrium;
- ukwehla okubukhali kushukela wegazi - hypoglycemia;
- ikhanda;
- isicanucanu kanye nokuphazamiseka kokugaya ukudla.
Lapho kuvela lezo zimpawu, kuyadingeka ukusula ngokuphelele umuthi bese uqala ukwelashwa okuyisibonakaliso nokuphindaphinda izindleko zamandla omzimba.
Eminye imiphumela ye-thioctic acid
Ngaphezu kwayo yonke imiphumela engenhla ye-lipoic acid, ingasiza abantu abakhuluphele ngokweqile. Ngokwemvelo, ukusetshenziswa kwemithi kuphela ngaphandle kokuzivocavoca ngokomzimba kanye nokudla okuthile kokudla ngeke kunikeze umphumela olindelekile futhi ohlala njalo. Kepha ngokuhlanganiswa kwazo zonke izimiso zokuncipha kwesisindo esifanele, konke kufanele kusebenze. Kulesi simo, i-lipoic acid ingathathwa imizuzu engama-30 ngaphambi noma ngemuva kokudla kwasekuseni, imizuzu engama-30 ngaphambi kokudla kwakusihlwa noma ngemuva kokuzivocavoca okukhulu komzimba. Umthamo odingekayo wokunciphisa isisindo uvela ku-25 kuye ku-50 mg ngosuku. Kulokhu, umuthi uyakwazi ukuthuthukisa imetabolism yamafutha kanye nama-carbohydrate futhi usebenzise i-cholesterol ye-atherogenic.
Futhi, amalungiselelo nezithasiselo eziqukethe i-lipoic acid nazo zingasetshenziswa ukuhlanza isikhumba esinenkinga. Zingasetshenziswa njengezakhi noma izengezo kuma-moisturizer nakokhilimu abondlayo. Isibonelo, uma ufaka amaconsi ambalwa esixazululo somjovo we-thioctic acid kunoma yikuphi ukhilimu wobisi noma ubisi, sisebenzise nsuku zonke futhi njalo, lapho-ke ungasithuthukisa kakhulu isimo sesikhumba, usihlanze futhi ususe ukungcola okungadingekile.
Eminye yemiphumela ebaluleke kakhulu ye-thioctic acid umphumela wayo we-hypoglycemic (amandla okwehlisa ushukela wegazi). Lokhu kubaluleke kakhulu kubantu abanesifo sikashukela sohlobo 1 nohlobo 2. Ohlelweni lokuqala lwalesi sifo, i-pancreas, ngenxa yomonakalo we-autoimmune, ayikwazi ukuhlanganisa i-hormone insulin, ebhekele ukwehlisa amazinga kashukela egazini, bese kuthi izicubu zomzimba ezimbili zikwazi ukumelana, okungukuthi, azinandaba nesenzo se-insulin. Uma ucabanga ngayo yonke imiphumela ye-insulin, i-lipoic acid isitha sayo.
Ngenxa yomphumela we-hypoglycemic, kungavimba ukuthuthukiswa kwezinkinga ezifana nesifo sikashukela i-angioretinopathy (umbono ongaboni kahle), i-nephropathy (umsebenzi wokulimala we-renal), i-neuropathy (ukwanda kokuzwela, ikakhulukazi emilenzeni, okufiphele ukukhula kwe-gang ganganne). Ngaphezu kwalokho, i-thioctic acid iyi-antioxidant futhi ivimba izinqubo ze-peroxidation kanye nokwenziwa kwama-free radicals.
Kumele kukhunjulwe ukuthi uma uthatha i-alpha-lipoic acid lapho kukhona isifo sikashukela, udinga ukuhlola njalo ngegazi futhi uqaphe ukusebenza kwawo, futhi ulandele izincomo zikadokotela.
Analogs nokubuyekezwa kwezidakamizwa
Ukubuyekezwa kwezidakamizwa eziqukethe i-lipoic acid kuvame ukuthi kube nokuhle. Abaningi bathi i-alpha lipoic acid ukwehlisa i-cholesterol iyithuluzi elibaluleke kakhulu. Futhi lokhu kunjalo, ngoba "kuyindawo yomdabu" yomzimba wethu, ngokungafani nezinye izidakamizwa ze-anticholesterolemic ezifana nama-statins nama-fibrate. Ungakhohlwa ukuthi i-atherossteosis ivame ukuhlotshaniswa nesifo sikashukela, futhi kulokhu, i-thioctic acid iba yindlela eyinkimbinkimbi yokwelashwa kokulungiswa.
Abantu abahlole lokhu kwelashwa bathi baphawule umkhuba omuhle esimeni sabo sonke. Ngokusho kwabo, bathola amandla nobuthakathaka buyanyamalala, imizwa yokuqina kokuqina nokuqina kokuzwela kwezitho inyamalala, ubuso buhlanzwa ngokusobala, imichilo nezinhlobonhlobo zokulimala kwesikhumba kuyahamba, isisindo sincishiswa lapho usebenzisa izidakamizwa ngokuzivocavoca nangokudla, futhi isifo sikashukela sincipha kancane ushukela wegazi, wehlisa inani le-cholesterol ezigulini ezine-atherosulinosis. Isidingo sokufeza umphumela owufunayo ukukholwa ekwelashweni nakwezokwelashwa okukodwa.
I-Lipoic acid iyingxenye yemithi enjalo kanye nezithasiselo zemvelo ezisebenzayo njenge-Oktolipen, i-Berlition 300, iComplivit-Shine, i-Espa-Lipon, i-Alphabet-Diabetes, iTiolepta, i-Dialipon.
Ngeshwa, wonke la mathuluzi awabizi impela, kodwa ayasebenza.
I-Lipoic acid ichazwe kuvidiyo kule ndatshana.
