I-Siofor: contraindication kanye nemiphumela emibi

I-Siofor isidakamizwa se-antidiabetic sethebhulethi. Umenzeli wayo osebenzayo yi-metformin.

Ithuluzi, njenganoma yisiphi esinye isidakamizwa, linezinombolo eziningi zokwephulwa. Uma uthatha isinqumo sokuthatha ukuthatha iSiofor, kubalulekile ukutadisha imiyalo nokubuyekezwa kweziguli.

ISiofor ithathwa njengomuthi othandwayo wokulwa nesifo sikashukela sohlobo 2. Umuthi nawo uyathathwa ukuze uvikeleke. I-Siofor yandisa ukuzwela kwamaseli emiphumeleni ye-insulin, okungukuthi, kunciphisa ukumelana kwe-insulin.

Inhloso yeSiofor

ISiofor 850 ibonwa ngephutha ngabantu abaningi njengezindlela, inhloso eyinhloko yayo ukunciphisa umzimba.

Inhloso enkulu yalo muthi ukunciphisa ushukela wegazi kubantu abanesifo sikashukela. Ukukhuluphala kulezi zimo kuvame kakhulu, kuvame ukuhlotshaniswa nokuxineka okukhulu koshukela egazini kanye nokwehla kwenqubo ye-metabolic.

Umuthi uqukethe i-metformin, esehlisa ushukela wegazi futhi wephule izinsalela ze-cholesterol. Ngakho-ke, abanesifo sikashukela bangancipha. Abantu abanempilo kwezinye izimo nabo basebenzisa lo muthi.

Ukubuyekezwa mayelana neSiofor yabantu abaphilile abafuna ukunciphisa umzimba kuningi okubi, ngoba ngaphandle kokukhuluma nodokotela futhi ulandele imiyalo, ukwehla kwesisindo akwenzeki, futhi imiphumela emibi iba khona.

Uma umuntu engenalo izinga eliphakeme ngokweqile le-glucose egazini, khona-ke ukwehla okubukhali kungaba yingozi, kuze kufinyelele ekuphazamisweni kwe-endocrine kanye nokuvela komqondo we-hypoglycemic, lapho ushukela wehlela inani eliphansi ngokweqile.

Isidakamizwa uSiofor sinezifiso ezilandelayo:

• I-Glycon.
• I-Bagomet.
• I-Glucophage.
• UGlatiniin.
• I-Vero-Metformin.
• IGlycomet 500.
• I-Dianormet.
• Langerine.
• Methadiene.
• Glyminfor.
• Metfogma 1000.
• Dormin
• I-Metospanin.
• I-Metformin.
• I-Metfogamma.
• Metfogamm 500.
• I-NovoFormin.
• I-Metformin-BMS.
• Siofor 500.
• Metformin Richter.
• ISofamet.
• IFomu.

Isenzo se-Pharmacological nokwakheka kwalo muthi

ISiofor umuthi owenzelwe ukwehlisa ushukela wegazi kubantu abanesifo sikashukela sohlobo 2 esiqinisekisiwe. Iziguli ezinjalo zivame ukukhuluphala.

Emiyalweni yethuluzi akukho datha yokuthi kungenzeka ukusetshenziswa kwayo ngabantu abanempilo yokunciphisa isisindo. Lapho i-metformin ingena emzimbeni wesifo sikashukela, ithinta amangqamuzana emisipha ukukhulisa amandla ayo okumunca ushukela osele egazini.

Lo mphumela usebenza kuphela emzimbeni wabantu abanesifo sikashukela sohlobo 2. Kulabo abangenaso isifo esinjalo, ukusetshenziswa kwezidakamizwa ezinjalo kuba yize. Okufanayo kusebenza kuSiofor wezidakamizwa.

Inkomba yedijithali, okuphoqelekile emva kwegama le-alfabhethi lomkhiqizo, yigama lomthamo wayo. Njengamanje, umuthi uSiofor uthengiswa kumithamo:

• 1000 mg
• 850 mg
• 500 mg

Indlela yokusebenza

Umuthi wehlisa inani elisisekelo loshukela egazini, kanye nenkomba yalo ngemuva kokudla. I-Metformin ayiphoqi amaseli we-pancreatic beta ukukhiqiza i-insulin eningi, okusho ukuthi i-hypoglycemia ngeke ivele.

Indlela yokunciphisa inani likashukela lapho usebenzisa uSiofor ukwandisa amandla amaseli ukuthola ushukela egazini. Ngaphezu kwalokho, ukuzwela kwe-insulin kwezingqimba zamaseli kuyanda.

ISiofor yehlisa izinga lokufakwa kwe-carbohydrate ekudleni emathunjini nasesiswini. I-Fatty acid oxidation nayo isheshisiwe futhi i-anaerobic glycolysis iyathuthukiswa. I-Siofor in sikashukela yehlisa indlala, nayo enomthelela ekunciphiseni isisindo. Ebantwini abangenaso isifo sikashukela, la maphilisi awanciphisi ukugcwala koshukela. Isenzo sikaSiofor kuleli cala asitholakali.

Abantu abanesifo sikashukela abathatha iSiofor futhi banamathele ekudleni okukhethekile kwesinye isikhathi banciphisa isisindo. Leli qiniso lisekela inganekwane yokuthi i-metformin iyindlela yokunciphisa umzimba.

Uma umuthi wehlise isisindo ngempumelelo, bekungabhekelwa kubo bonke abanesifo sikashukela.

Ngeshwa, abantu abanesifo sikashukela abasebenzisa uSiofor isikhathi eside ukusuka ku-500 kuye ku-850 mg kaningana ngosuku akuqabukeli ukulahlekelwa okubalulekile kwesisindo.

Imiyalo yokusebenzisa umuthi

Umthamo wesidakamizwa unikezwa kuphela udokotela ohambelayo. Njengomthetho, ukusetshenziswa komuthi kuqala ngethamo elincane le-500 mg.

I-Siofor ichazwe kumthamo wokuqala we-500 mg / ngosuku, ngokuhamba kwesikhathi, inani lenyuka kuze kufinyelele amanani afunekayo. Ngemuva kwezinsuku eziyi-10 kuye kwezingu-15, umthamo kufanele ulungiswe kusetshenziswa inkomba kashukela wegazi. Ukwanda kancane kancane komthamo kuthinta kahle ukuzwela kokulungiswa kwendlela yokugaya ukudla.

Umthamo omkhulu we-0.5-3 g metformin hydrochloride uvunyelwe ngosuku, lokhu kuhambelana namathebulethi we-Siofor 500 noma ama-3 g kuya kwayi-3 e-Siofor 1000. Lomthamo ungasetshenziswa kathathu ngosuku, kepha, ezimeni eziningi. ukwelashwa kwesifo sikashukela kwanele i-100 mg kabili ngosuku.

Ukufinyelela ukulungiswa okungcono koshukela wegazi, i-metformin ihlanganiswa ne-insulin.

Okokuqala, iSiofor inqunywa izikhathi ezingama-500 kuye ku-850 mg kaningana ngosuku, kanti inani le-insulin lincike ezingeni likashukela egazini. Umuthi kufanele uphuzwe nokudla, ngaphandle kokuhlafuna, uwuphuze ngenani elilinganayo loketshezi.

Umthamo we-500 mg uvame ukusetshenziselwa uma kune-prediabetes noma umuntu evame ukunciphisa umzimba. Uma umuntu onesifo sikashukela engenayo imiphumela emibi ngemuva kwesonto lokusetshenziswa, inani lomuthi liyakhuphuka, ngokwesibonelo, kusetshenziswa iSiofor 850 noma elinye ithebhulethi likaSiofor 500 lingezwa emahoreni ayi-12 ngemuva kokuqala. Isonto ngalinye, i-500 mg ye-metformin yengezwa kancane kancane, kepha kubalulekile ukubhekisisa njalo ukuba khona noma ukungabikho kwemiphumela emibi.

Uma inani lomuthi uSiofor landa, khona-ke imiphumela emibi kungenzeka kakhulu. Ngemuva kwalokho udinga ukwehlisa umthamo uze ufike kwisamba esedlule. Ngokuhamba kwesikhathi, kufanele uphinde uzame ukwandisa inani lomuthi lusebenze kakhulu.

Uma umthamo obekiwe womuthi ungama-500 mg, udakwa 1 isikhathi kusihlwa, ngaleyo ndlela unciphise ubungozi bemiphumela emibi. Uma umthamo ungu-1000 mg ngosuku, khona-ke umthamo uhlukaniswe ngemithamo eminingana.

Kubalulekile ngesikhathi sokwelashwa ngezidakamizwa zalesi sigaba ukwenza njalo izivivinyo ezibonisa ukusebenza kwesibindi nezinso. Ikakhulu, okulandelayo kufanele kwenziwe:

1. ukuhlolwa kwegazi okujwayelekile
2. ukuhlolwa kwegazi kwe-biochemical (ama-enzyme wesibindi, i-creatinine).

Uhlu lokuphikisana

I-Siofor 850 yisidakamizwa esinamandla esinganconywa ukuthi sisisebenzise ngaphandle kokubonana nodokotela.

Uma kwenziwa isinqumo sokuthatha uSiofor, khona-ke lokhu kungqubuzana okulandelayo:

• ukuzwela okuphezulu kuzakhi zomkhiqizo,
• izinkinga ze-endocrine,
• ukwehluleka ukuphefumula
• Uhlobo 1 sikashukela
• ukwehluleka kwesibindi nezinso,
• ukulimala okungathi sína
• infaration myocardial esiteji sokukhuphuka,
• izifo ezithathelwanayo ezinzima
• imisebenzi yamuva
• isimila se-oncological,
• uphuzo oludakayo,
• ukukhulelwa
• ukudla okuphansi kwekhalori
• iminyaka yezingane
• ukuncelisa.

Odokotela banquma umuthi ezimweni ezimbi kakhulu. ISiofor 850 kufanele ithathwe ngokuqapha:

1. abantu abangaphezu kweminyaka engama-60
2. izingane ezingaphansi kweminyaka engu-12
3. abantu abahlala bechayeka kakhulu ngokomzimba osindayo.

Kunenkinga eyingozi evela ekuthatheni iSiofor, lokhu kuyi-lactic acidosis. Lesi simo sidinga ukulashwa okuphuthumayo nokwelashwa ezimweni ezinakekelwa kakhulu.

I-Lactic acidosis inezimpawu ezilandelayo:

• ukwehla okukhulu kwezinga lokushisa,
• ukushaya kwenhliziyo okuhamba kancane
• ukwehluleka ukuphefumula
• ukuphazamiseka kwesigqi senhliziyo,
• ubuthakathaka kanye nokubola,
• kwehle umfutho wegazi.

Ukusuka eSiofor kunemiphumela emibi ekhuphuka ngemuva kokuzivocavoca okunamandla komzimba. Ukunganaki leli qiniso, abesifazane abaningi baqala ukuthatha lesi sidakamizwa ukuze banciphe, bahlanganise ukwamukela nemithwalo ejimini noma echibini. Ngakho-ke, umphumela olindelekile awenzeki.

Ngenxa yokusebenzisa ngokungacabangi kukaSiofor, kuvela izibuyekezo ezingezinhle mayelana nomuthi.

Kufanele futhi kuqashelwe ukuthi amathuba okuthi i-lactic acidosis inyuke uma uphuza utshwala.

I-Siofor yokuvimbela isifo sikashukela sohlobo 2

Ukuvimbela ukwakheka kwesifo sikashukela sohlobo 2, kubalulekile ukunamathela njalo empilweni enempilo. Ngakho-ke, kufanele ukhulise umsebenzi wakho womzimba futhi ushintshe uhlelo lokudla okunempilo.

Iningi leziguli empilweni yansuku zonke alithandi ukulandela izincomo zendlela yokuphila. Udaba oluphuthumayo ukudalwa kwecebo lokuvimbela isifo sikashukela sohlobo 2 usebenzisa uSiofor.

Eminyakeni eyi-10 eyedlule, kwavela izincomo ezivela ku-American Diabetes Association ngokusetshenziswa kweSiofor ekuvinjelweni okuyinhloko kwesifo sikashukela i-mellitus. Ucwaningo lwesayensi luhlale iminyaka emithathu, ngenxa yakhe kwaziwa ukuthi ukusetshenziswa kweGlucophage noma iSiofor kwehlisa amathuba okuba lesi sifo sakhiwe ngama-31%.

Uma umuntu eshintsha ngokuphelele indlela yokuphila enempilo, khona-ke le ngozi izokwehla ngo-58%. Ukusetshenziswa kwamacwecwe e-metformin njengendlela yokuvimbela kunconyelwa iziguli ezinobungozi obukhulu bokuthola isifo sikashukela.

Leli qembu lifaka abantu abangaphansi kweminyaka yobudala engama-60 abakhuluphele ngokweqile, abanesici esisodwa sengozi eyodwa noma ngaphezulu, okungukuthi:

1. i-glycated hemoglobin - ngaphezu kwe-6%,
2. umfutho wegazi ophakeme
3. Yehlise i-cholesterol ephezulu kakhulu egazini,
4. triglycerides ephezulu,
5. thayipha isifo sikashukela ezi-2 ezihlotsheni eziseduze,
6. inkomba yomzimba ngaphezulu kwe-35.

Iziguli ezinjalo zingathatha uSiofor ukuvimbela isifo sikashukela. Umthamo kuleli cala uvela ku-250 kuya ku-850 mg kabili ngosuku. Njengamanje, iSiofor noma ehlukile, isidakamizwa iGlucofage yiso kuphela isidakamizwa esibhekwa njenge-prophylactic ngokumelene nesifo sikashukela.

Gcina ngaphansi kokusebenza komsebenzi wezinso nesibindi kufanele kube ngaphambi kokuqokwa kwemali nge-metformin bese kuthi njalo ezinyangeni eziyisithupha. Ngaphezu kwalokho, kubalulekile ukuhlola amazinga we-lactate wegazi kabili ngonyaka. Ekwelashweni kwesifo sikashukela i-mellitus ngokuhlanganiswa kweSiofor ne-sulfonylurea derivatives, kuvela amathuba aphezulu we-hypoglycemia.

Ukuqapha njalo kwamazinga kashukela wegazi kuyadingeka, kuze kube kaningana ngosuku. Ngenxa yobungozi be-hypoglycemia ezigulini ezithatha i-Glucofage 850 noma iSiofor, akunconywa ukwenza imisebenzi edinga ukunakwa okwandayo kanye nokuphendula okukhulu kwe-psychomotor.

Izindleko

Njengamanje, intengo yomuthi iyahlukahluka ngokuya ngomthamo wayo. Njengomthetho, iphakethe leSiofor 850 libiza cishe ama-ruble angama-350.

Isazi sevidiyo esikulesi sihloko sizosho mayelana ne-hypoglycemic agent uSiofor.