Ama-pancreas afaka ujusi lolu, aqukethe i-enzyme ekhethekile, i-pancreatic amylase, eklanyelwe ukudiliza izingxenye eziyinkimbinkimbi zaba ngamakhompiyutha wokugaya kalula. Amamolekyuli e-Amylase aguqula isitashi nama-pectin abe yi-sucrose ne-maltose, kuyilapho engabambi iqhaza ku-hydrolysis ye-fiber.
Inani lemvelo le-enzyme likhulu impela, ikakhulukazi kwizitho zohlelo lwesisu. Ngokwezinga lale nto, udokotela angakwazi ukubona ukuthi i-pancreas yomuntu iphilile kangakanani. Ekutholakalweni kwezimo zokuphazamiseka kwe-pathological kanye nokuphazamiseka okuningi, ukuhlaziywa okuningiliziwe kwezinkomba ze-amylase (kukhuphuka noma kukhuphukile) kuyasiza.
Ukuthola idatha eyiqiniso kakhulu yokutholwa kwezifo, kusetshenziswa amapharamitha wezifundo ezimbili, okukhombisa inani lama-amylase kumchamo nasegazini. Ukusungulwa kwe-diastases kumchamo kuyinqubo enobunzima, izinto ezibonakalayo zithathwa ezingxenyeni, njalo emahoreni ama-3. Ukuhlolwa okulula kwe-amylase kuzoba ukucwaninga kwegazi elithathwe emthanjeni we-ulnar.
Ukucwaninga okunjalo kunesizathu sokunquma izinga lomsebenzi we-enzyme, ukuxilongwa kwezindlela ezahlukahlukene zenqubo yokuvuvukala kumanyikwe. Kunolwazi oluyi-40% kunokuhlaziywa kwe-lipase. Indlela yokuxilonga nayo yenziwa ukuthola izifo ezilwaneni, njengamakati.
Amanani wokuphambuka
I-Amylase enkambweni yokuvuvukala kakhulu ikhuphuka kaningana ngokushesha, imvamisa izinguquko ezinjalo zibonisa ukuqala kwesimo se-pathological noma ukwanda kwesifo. Izinkomba zikhula kungakapheli amahora angama-3-5, zifinyelele inani eliphakeme ngemuva kwamahora ayi-10-24. Ngemuva kwalapho kunokwehla, ngosuku 6, izinga lama-amylase lehla lalijwayelekile.
Ukuthola imiphumela ethembekile, kuyadingeka ukuthi sihlaziye umsebenzi we-amylase kumchamo wansuku zonke, obalulekile lapho kwenziwa ukuxilongwa, kepha umphumela awucacanga ngendlela ebaluleke kakhulu yalesi sifo.
Kwi-pancreatitis engapheli ngaphandle kokukhula ngokweqile, izinga lama-amylase lingancishiswa kancane, lapho kubuye kwenzeke, inani le-enzymes le-pancreatic liyanda. Kwezinye iziguli, ukugcwala okujwayelekile kwento akuhlanganisiwe ngisho nangokwengeziwe.
Ama-pancreatic lipase nama-amylase ayanda ezimweni ezinjalo:
- ukukhipha isisu;
- ukulimala kwesisu;
- nezinye izifo.
Izizathu zokwanda okusheshayo kwezinkomba zihambisana namatshe ku-gallbladder, izinso, neoplasms ye-oncological kanye nokuphazamiseka kwe-bile.
Kwenzeka ukuthi ukuhlaziywa kwe-biochemical kunikeza umphumela we-zero, lokhu kwenzeka lapho imisebenzi ye-pancreatic inganele, kanye nesigaba se-hepatitis esibi nesingapheli. Amazinga aphansi we-amylase awuphawu lwe-toxicosis ngesikhathi sokukhulelwa.
Ukuze uthole ukuxilongwa okuyiqiniso, kuzodingeka uthathe izivivinyo ezingeziwe, uhlole umzimba ngokugcwele.Izinga elijwayelekile lezinto limi ngale ndlela: ezinganeni ezingaphansi konyaka owodwa ubudala, inkomba ye-amylase ingaphansi kwengu-8, enganeni eneminyaka eyi-1-10 ubudala - ngaphansi kwengama-31, ebusheni - ngezansi 39, kumuntu omdala - ngezansi Amayunithi angama-53 / ilitha Akuwenzi mehluko ukuthi isiguli sinjani.
Ukweqisa okuncane - lapho ukuhlaziya kukhombisa amayunithi ambalwa kakhulu kunokwejwayelekile, umuntu akaphazamiseki, akakhalazi ngempilo. Ezimweni ezinjalo, udokotela umane anqume ama-Pancreatin noma amalungiselelo afanayo we-pancreatic enzyme.
Izinkomba kufanele zikuxwayise izikhathi eziphindwe kabili noma ngaphezulu (eziphansi) kunokujwayelekile.
Umphumela wenyuswa noma wehla nini?
Nge-pancreatitis, i-amylase inqunywa ukubonga ekuhlolweni kwegazi okune-biochemical okuningiliziwe, khona-ke kwenziwa izinguquko ezahlukahlukene, kufinyeleleke isiphetho futhi kunikezwe ukwelashwa okwanele. Isampula yegazi yenziwa esiswini esingenalutho, okwathi emva kwalokho kwaqalwa ukwakhiwa kwe-serum. Ukuze kuhlaziywe umchamo, izinto eziphilayo zibuthwa ngosuku, ingxenye yomchamo yasekuseni ithululelwa, okusele kuqoqwa phakathi nosuku, ukuqoqwa kuqeda ngengxenye yokusa yomchamo ngosuku olulandelayo.
Ukuhlolwa kwegazi kwe-pancreatic amylase kufanele kukhombise ukungabikho kwayo, le enzyme imvamisa ayibikho egazini.
Lapho into ingena endaweni engajwayelekile (igazi, umchamo), zikhuluma ngokuqala kokuphazamiseka okuthile.
Njengoba kunenkomba ekhuphukayo egazini, inani lama-amylase kumchamo nalo lidlula okujwayelekile, lokhu kuyimaki lokuthola i-pathologies yezitho zangaphakathi. Ukukhula kwe-pancreatic amylase egazini kungaba yisibonakaliso:
- ama-mumps;
- ukugula kwezihlakala zesikhumba;
- cholecystitis.
Inani elivumelekile kufanele lihlale ngaphakathi kwe-28-125 U / L (igazi), 1-17 U / L (umchamo). Ukuhlaziywa kwe-pancreatic amylase kuboniswa ukuxilongwa okuyinkimbinkimbi, kukuvumela ukuthi usungule lesi sifo isikhathi futhi uqale ukwelashwa.
Udokotela unikeza ukuhlaziywa kwe-amylase, ngokuyinhloko ukuthola uhlobo olubi lwe-pancreatitis, amanye ama-pancreatic pathologies, kepha futhi nokuxilongwa kwe:
- ukukhulelwa kwe-ectopic;
- i-hyperamylasemia;
- izinga le-P-isoenzyme;
- ukwehluleka kwezinso;
- isilonda se-peptic sesisu kanye ne-duodenum.
Ngaphezu kwalokho, lokhu kuhlaziywa kuzokhombisa umsebenzi wezinso ongasebenzi kahle, ukwehluleka kwezinso, ukuvinjwa kwamathumbu, izinqubo zokuvuvukala emgodleni wesisu, ikakhulukazi i-peritonitis, indlela eyingozi yotshwala, kanye nokungasebenzi kahle kwe-gland ngemuva kokuhlinzwa.
Izinga eliphansi le-amylase ngokuvamile alinakwa kangako, kepha amanani aphansi futhi kufanele abe uphawu lokuxilonga, okubonisa ukuthi umsebenzi we-pancreatic awanele. I-cystic fibrosis, ethinta cishe noma yiziphi izitho zangaphakathi, ingadala ukwephulwa. Isithombe esifanayo sibonwa ezigabeni zokugcina zomdlavuza, okhombisa ukufa okusondele kwesiguli.
I-cholesterol ephezulu yegazi, i-homocysteine ​​ingakhuphula noma inciphise i-amylase yegazi, lokhu kuyabonakala uma, ngaphambi kokuxilongwa, isiguli saphuze imithi ethile: ukulawula ukuzalwa, izidakamizwa, i-diuretics, i-Ibuprofen kanye nokuphuma kwayo.
Kuzodingeka ukuthi unake ukuthi ushintsho kunani eliphelele lama-amylase elinesikhombi esiphansi se-pancreatic amylase libonisa ukwephulwa kwama-pancreas, izicubu zokuphefumula, ne-ovarian pathologies.
Ungakulungiselela kanjani ukuhlaziya
Ukuthola umphumela onembe kakhulu, udinga ukulungiselela isifundo ngokufanele. Ekuseni, ngaphambi kokunikela ngegazi, isiguli kufanele senqabe ukudla ukudla neziphuzo ezahlukahlukene, ikakhulukazi ikhofi netiye. Ngobuningi obungenamkhawulo, amanzi ahlanziwe futhi angenawo amakhabethe ayavunyelwa.
Ngaphambi kokuhlolwa, isidlo sokugcina akufanele senziwe kungakapheli amahora ayi-12. Kunemithetho ekhawulela ukusetshenziswa kwemithi, imvamisa odokotela baluleka ukuthi bayeke ukuphuza imithi emasontweni ama-1-2 ngaphambi kokuhlaziywa. Uma isiguli nokho singasinakanga lesi sincomo, kufanele utshele udokotela ngaso.
Ngosuku olwandulela ukulethwa kwezinto ezibonakalayo, umsebenzi omkhulu womzimba, ukusetshenziswa kotjwala abufakiwe. Ukwelashwa komzimba, kufaka phakathi i-rectal kanye ne-fluorographic fluoroscopy, ne-ultrasound, kungathinta umphumela wokuhlaziywa.
Ezinye izifo zinganciphisa i-pancreatic amylase, umphumela ungahluka ngokwephulwa:
- i-hepatitis;
- ukungasebenzi kahle kwe-carbohydrate metabolism;
- isigaba sesine sokulimala kabi kwamanyikwe;
- ama-neoplasms kwizicubu zamanyikwe;
- ukubhujiswa ngokuphelele kwama-pancreas;
- izinga eliphakeme lokuqina kwegazi cholesterol.
Lapho lesi sifo sihlotshaniswa nenqubo yokuvuvukala, kukhiqizwa i-pancreatic amylase ngamanani amakhulu, ama-pancreatic amylase akhuphuka amashumi ezikhathini. Ukuhlushwa okukhulu kuhlotshaniswa nokugula: i-pancreatitis engapheli futhi eyingozi, ukuvinjwa kwama-ducts, isimila, ukuvinjwa kwamathumbu, isikhathi esingapheli futhi esibi sesifo se-gallstone, ukuvuvukala kwesibindi, ukuba khona kokutheleleka okuphathelene nesihlungu esiswini, i-appendicitis eyingozi.
Kuyingozi ukwelapha izifo ze-pancreatic ngaphandle kokubamba iqhaza kukadokotela, noma yiluphi uhlelo luzothinta isimo sezempilo. Ukhiye wokuxolelwa isikhathi eside kuzoba ukunamathela ngokuqinile kwimiyalelo kadokotela, ukuthuthukisa ikhwalithi yempilo, ukuphuza imithi ebekiwe.
Imininingwane ngama-enzymes e-pancreatic inikezwe kuvidiyo kule ndatshana.
