U-Omez ungumuthi we-antiulcer wemvelaphi yokwenziwa. Isithako esikhulu esisebenzayo yi-omeprazole, izakhi ezisizayo ngamanzi angenamanzi, i-sucrose, i-sodium phosphate, i-sodium lauryl sulfate. Khipha ifomu - i-lyophilisate yokulungiswa kwezixazululo namaphilisi we-gelatin. Ama-ampoules awatholakali.
Amakhandlela aqinile, anomzimba obonakalayo. Kuzo zombili izingxenye zefomu lethebhulethi kunombhalo - "OMEZ". Ukugcwalisa - imifino encane kunazo zonke yomthunzi omhlophe, kwiphakeji elilodwa lezingcezu eziyi-10 noma ezingama-30.
Into esebenzayo yesidakamizwa inomphumela we-antiemetic, isiza ukwandisa ithoni ye-sphincter ye-Oddi, isheshisa ukuthulula okungokwemvelo kwamathumbu ngokumelene nesizinda sokwehla kwenqubo.
Umphumela wesidakamizwa kwenzeka ihora elilodwa ngemuva kokufaka isicelo. Umphumela wesikhathi eside uhlala amahora angama-24, uhlanganiswe. Cabanga ngalokhu: u-Omez ubekelwe ini, imithetho yokusebenzisa kanye nama-analogues.
Isenzo se-Pharmacological
Ngokusho kwesichasiselo, u-Omez ungumuthi we-antiulcer ophakathi kweqembu lama-proton pump inhibitors. Into esebenzayo ngesimo se-omeprazole, efakwe kumakhompiyutha e-gelatin, igqugquzela ukunqandwa kwe-hydrochloric acid, okuholela ekutheni kube nomphumela othile kuma-enzyme amaseli wesisu.
Leli ketanga livusa ukuqothuka kwesigaba sokugcina sokukhiqizwa kwe-hydrochloric acid. Ithuluzi lisebenza kungakhathalekile ukuthi hlobo luni lokucasulayo. Ukwehla komsebenzi we-basal nokuvuselelwa secretion kuyabonwa.
Amathebulethi aqala ukusebenza imizuzu engama-60 ngemuva kokufaka isicelo. Isikhathi somphumela wokwelapha amahora angama-24. Ngemuva kokuthi umuthi ukhanseliwe, umsebenzi oyimfihlo wezindlala ezikhulayo zegciwane lesisu uvuselelwa ezinsukwini ezingama-3-6.
I-Omeprazole inempahla yokumunwa ngokushesha kwamathumbu. Njengoba umuthi utholakala emigodini egomela i-acid, imunca kuphela ipheshana lesisu somuntu. Kumanzi we-biological, okuqukethwe okukhawulelayo kwengxenye esebenzayo kubonwa ngemuva kwemizuzu engama-60. Izinga le-bioavailability lingama-40%. Umuthi ulolongwa esibindini.
Ngokwazisa kokumiswa, kutholakala izithiyo zokucasha kwesisu, izinga lazo linqunywa umthamo. Izokhonjiswa ngemuva kokuphathwa kwe-intravenous imizuzu engaba ngu-40.
Izinkomba, ama-contraindication kanye nemiphumela emibi
Izinkomba zokusetshenziswa - isilonda se-peptic se-duodenum 12, isisu; ulcerative noma indlela yokuwohloka yesophagitis; ama-ulcerative pathologies ngenxa yokwelapha izidakamizwa ezingeyona i-antiidal.
Udokotela angakunikeza umuthi wesilonda esisesiswini, osuselwa ekucindezelekeni okungapheli, ekwelapheni i-pancreatitis, uhlobo oluhlelekile lwe-mastocytosis. Uma isiguli singakwazi ukuthatha amaphilisi, khona-ke into esebenzayo kufanele iphathwe kahle.
Njengoba sesihlolile u-Omez, kungani edingeka, sathola ama-contraindication ukuthi asetshenziswe: akufanele athathwe ngesikhathi sokukhulelwa ngabesifazane, nge-lactation. Musa ukunquma ebuntwaneni. Ngokuqapha ngokweqile, thatha ngokumelene nesizinda sokwehluleka kwezinso nezinso. Lawa macala amabili adinga indlela yomuntu ngamunye, imithamo nokuqashwa njalo kwezokwelapha.
Umuthi ubekezelelwa kahle yiziguli, kepha ungadala imiphumela emibi:
- Ubuhlungu esiswini, isicanucanu, ukuphazamiseka komgudu wokugaya ukudla - isifo sohudo, ukuqhakaza, ukwanda kwegesi, ukuphazamiseka kokuqonda ukunambitheka, umsebenzi owengeziwe wama-enzyme wesibindi.
- Ukusuka ohlelweni lokujikeleza kwegazi, i-leukopenia noma i-thrombocytopenia kungenzeka.
- Ubuhlungu bekhanda, isiyezi, ne-Depression syndrome yimiphumela emibi ekhombisa ukwephulwa kohlelo lwezinzwa oluphakathi.
- I-Myalgia ne-arthralgia.
- Ukusabela komzimba ngendlela yokuqhuma, ukulunywa kwesikhumba, i-hyperemia, amaphaphu.
Kuyaqabukela kube khona ukwephulwa kokubona okubukwayo, ukujumbana okujwayelekile (ubuthakathaka, ukunganaki, ukulahleka kwesifiso sokudla), ukukhuphula umjuluko.
Imiyalo yokusebenzisa umuthi u-Omez
Ama-capsel eGelatin kumele athathwe ngomlomo, awavulwa, ahlafunwe, afohlwe nangezinye izindlela. Ngokuxilongwa kwesilonda se-peptic thatha u-20 mg ngosuku. Sebenzisa ngaphambi kokudla kuphela.
Isikhathi sokwelashwa siyizinsuku eziyi-14. Lesi sikhathi sekwanele ukuthi isilonda sokulimala singaphola. Uma lokhu kungenzeki, lapho-ke kungcono ukwandisa inkambo yokwelashwa amanye amasonto amabili. Kwimidwebo eminingi, ukwelashwa kuthatha izinsuku ezingama-30.
Ukwelashwa kwe-Zollinger-Ellison syndrome, kunconywa abangama-60 mg ngosuku. Thatha ngaphambi kokudla. Umphumela omangazayo ubonwa ngemuva kwamasonto ambalwa - uzibonakalisa ngesimo sokwehla kwezimpawu ezingezinhle. Umthamo wesondlo unqunywa ngokuhlukile.
Isikhathi sokusetshenziswa kwe-gastritis cishe siyizinsuku eziyi-14. Umgomo wokwelapha ukususa izimpawu zesisu esicashile. Thatha i-1 capsule ngosuku. Ngaphezu kwalokho, ezinye izidakamizwa zinqunyelwe.
Izici zokwelashwa kwe-pancreatitis nge-Omez:
- I-Omez inconyelwa kuphela njengengxenye yokwelashwa okuphelele kanye nezinye izidakamizwa. Isiza ukunciphisa izinhlungu, ikhulule ukushisa kwenhliziyo, yehlise umthwalo kumanyikwe.
- Igama lokwelashwa libangelwa ubukhulu besithombe sasemtholampilo.
- Uma kwenzeka ukwanda, kufanele kuthathwe amaphilisi amabili.
- Lapho izimpawu ziba buthakathaka, isiguli sidluliselwa esifundweni sokugcina - i-1 capsule ngamahora angama-24.
Ukuphathwa kwe-Intravenous kwenziwa ngenxa yezizathu eziqinile zokwelashwa. Umthamo wehluka ngokuya ngesifo esithile kanye nobunzima bomtholampilo - 40-80 mg ngosuku. Uma umthamo ungama-60 mg, imvamisa ihlukaniswe imijovo emibili. Ngemuva kokususa izimpawu ezinzima, bashintshela kwifomu lomuthi wethebhulethi. Ukugcinwa kokumiswa okulungiselelwe - akukho ngaphezulu kosuku.
Umuthi ungathengwa ekhemisi, intengo incike kwinani lamaphilisi kanye nomenzi wesidakamizwa. Intengo ye-Omez (amaphilisi ayi-10) ngama-ruble angama-70 (umenzi weNdiya), intengo yamathebulethi angama-30 icishe ibe ngama-ruble angama-200. I-Powder yokumiswa ibiza ama-ruble angama-70-90.
Imiyalo ekhethekile
I-pancreatitis ihlukaniswa ngokwezinto zokuzalwa, ubunzima kanye nezinye izindlela, udokotela kuphela onquma ukwelashwa. I-Omez kuhloswe ngayo ukubulala izinzwa, ukunciphisa ubukhulu bezimpawu ezethusayo.
Ukudlula umthamo wesidakamizwa kuholela ekukhuleni kwezimpawu ezingezinhle, azisongeli impilo yesiguli. I-overdose ibonakaliswa ukungahambi kahle kokubonakalayo, umlomo owomile, ukozela okushisayo, ikhanda kanye ne-tachycardia.
I-antidote ayikho. I-Hemodialysis ayisizi ukudambisa izimpawu zokukhathazeka. Ukwelashwa okuyisibonakaliso kuphela ngenxa yokuvezwa kwemitholampilo okukhethekile kunconywayo.
Isichasiselo sikhombisa ukusebenzisana kuka-Omez nezinye izidakamizwa. Uma umuthi olwa ne-ulcer neKetoconazole, i-Intraconazole (izidakamizwa zokwelapha izifo zokukhunta) usetshenziswa ngasikhathi sinye, ukwehla kokusebenza kokugcina kutholakala. Ukusetshenziswa okufanayo kwe -cacithromycin kuholela ekwandeni komphumela wokwelapha wazo zombili lezi zidakamizwa.
Eminye imiyalo ekhethekile:
- I-Omez njengokuvimbela okwanda kwe-pancreatitis ayinconywa.
- Umyalo ukhombisa ukuthi umuthi kufanele uphuzwe ngaphambi kokudla. Kodwa-ke, ukuthatha ukudla noma ngemuva kokudla akunqunyelwe - ukusebenza kahle kwezidakamizwa ze-pharmacological akupheli.
- Ngaphambi kokuthatha amaphilisi noma ukusebenzisa imithambo, kufanele uhlole ubukhona bezinqubo ezimbi.
- Ngesikhathi sokulashwa kwamanyikwe, ungashayela imoto, wenze imisebenzi edinga ukunakwa okukhulu.
- Umuthi awubekelwe izingane ezingaphansi kweminyaka engu-12 ubudala, ngoba azikho izivivinyo zomtholampilo ezenziwa ngemiphumela emzimbeni wezingane.
Imiyalo ayiqukethe idatha ephathelene nokuhambisana notshwala. Kodwa-ke, ukuphuza utshwala akukunconywa, ngoba i-ethanol iwathinta kabi amaseli we-pancreatic owonakele, okuholela ekwandeni kwesithombe somtholampilo.
Ngesikhathi sokubeletha kwengane nokuncelisa, umuthi awenziwa. Zingabekelwa izinkomba ezibalulekile. Qiniseka ukuthi ubheka izinzuzo ezingaba khona kumama, ukulimala okungenzeka enganeni.
Uma udinga ukuthatha uhhafu we-capsule, bese ukwenze ngale ndlela: vula i-capsule, okuqukethwe kuhlanganiswa ne-applesauce (1 isipuni). Ngenye indlela, isigamu sepilisi ngeke sithathwe.
Ukufana kwezidakamizwa
Ukwahlukaniswa kwezidakamizwa kukuvumela ukuthi uhlanganise umuthi u-Omez noDiaprazole eqenjini elilodwa lezidakamizwa. I-Diaprazole inento efanayo esebenzayo, imiselwe ukwelashwa kwe-pancreatitis, izilonda. Ukukhishwa ifomu - i-powder yokuhlanjululwa kwekhambi namathebulethi.
Musa ukuqoka izingane ngokubekezelela i-organic. Ngokuqapha ngokweqile, baphathwa ngokumelene nesizinda sokuhluleka kwe-renal nesibindi. Imiphumela emibi yokugaya ivame ukukhula - isifo sohudo, isicanucanu, ubuhlungu besisu, ukuqubuka okujwayelekile.
Ezinye izifaniso ze-Omez ngemiphumela yokwelapha zibandakanya i-Omeprazole, iCrismel, i-Omecaps, iGastrozole, i-Omeprazole-Darnitsa (isidakamizwa sasekhaya). Ukwelashwa kwe-pancreatitis, ama-analogues ngokuvamile ahlanganiswa nemithi ye-enzyme.
Iziguli eziningi zibuza ukuthi yikuphi okungcono, i-Omez noma iNolpaza? Umuthi wokugcina unomphumela ofanayo wokwelapha, usiza ekunciphiseni ukugcwala kwe-hydrochloric acid emzimbeni, ukhulule izimpawu zokungasebenzi kahle kwendlela yesisu. Ukwakheka kuqukethe enye into esebenzayo - i-pantoprazole. Le ngxenye isebenza ngandlela-thile ngokushesha kune-omeprazole.
Ake sibheke imininingwane ngemininingwane:
- Amaphilisi we-Ultop anconywa ekwelapheni izilonda ze-peptic nezingcindezi, i-pancreatitis engapheli, izifo zezilonda zanoma ikuphi i-etiology. Kuvunyelwe ukusetshenziselwa ukushisa kwenhliziyo nezinye izimpawu ze-dyspeptic. Yabela njenge-prophylaxis yezilonda lapho uthatha izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala. Musa ukuthatha ngesikhathi sokukhulelwa, ngokumelene nesizinda se-pathologies enzima yezinso nesibindi, ngokubekezelela ifa le-tructose.
- U-Omeprazole uyi-proton inhibitor. Ifomu lomthamo - i-powder yokumiswa kanye namathebulethi. Kwi-pancreatitis engapheli, kuvame ukunqunyelwa, ngoba kunciphisa ingcindezi engaphakathi kwama-pancreatic ducts, kuvimbela ukukhululeka kwama-enzyme, okuvumela ukunciphisa umthwalo kusuka kumanyikwe. Umuthi unciphisa izinhlungu zesisu, ukushisa kwenhliziyo, ukunambitheka okumuncu emlonyeni nezinye izimpawu ezihambisana nokuvuvukala okuvilaphayo.
- IGastrozole. Isithako esisebenzayo siyefana no-Omez. Kutholakala kwifomu le-capsule. Nge-pancreatitis, ama-20-30 mg ngosuku athathwa. Umthamo ukhethwa ngawodwana, njengenkambo yokwelashwa. Ukuqapheliswa kwezinkinga ngezinso nesibindi, akwenziwa ngesikhathi sokuthwala kwengane.
Kunabalingani abaningi baka-Omez okunzima ukuwaqonda. Abanye abantu bayazibuza ukuthi yisiphi isidakamizwa esihamba phambili. I-Ranitidine ayihlukile kunomuthi okukhulunywa ngawo, ngakho-ke konke kuncike ekukhetheni kukadokotela. I-Pariet inenye into esebenzayo, kepha ayifani ngokwelashwa, ngakho-ke kunconyelwa ukwelashwa kwe-pancreatitis engapheli.
UDe Nol ubukeka njengethuluzi elinamandla ngokwengeziwe uma uqhathanisa no-Omez. Ngokuvamile kunconyelwa ukwelashwa kwezinhlobo ezinzima zokuvuvukala kwe-pancreatic. Kepha une-contraindication eyengeziwe, kuvame ukwenzeka izehlakalo ezingezinhle, okuholela ekukhanselweni kwayo.
Umehluko phakathi kuka-Omez no-Omez D ukwindlela yokwakheka, umphumela wezokwelapha awuhlukile. Umuthi onesiqalo "D" awuqukethe i-omeprazole kuphela, kodwa futhi ne-domperidone - izinto ziqinisa isenzo somunye nomunye.
U-Omez uchazwe kuvidiyo ekulesi sihloko.
