Abaningi banentshisekelo embuzweni wokuthi aphumelela kangakanani amaphilisi we-Siofor 850 okwehlisa isisindo, kanye nokwelashwa kwesifo sikashukela.
Kumele kwaziwe ukuthi iSiofor 850 ngesinye sezidakamizwa ezisebenza kahle ezisetshenziselwa ukwelapha isifo sikashukela sohlobo 2. Ngaphezu kwalokho, banegalelo ekunciphiseni isisindo kwesiguli ngempumelelo. Futhi njengoba wazi, cishe zonke iziguli ezinokuxilongwa okungenhla zinokukhuluphala ngokweqile.
Umuthi lo unemiyalo esetshenziswayo, ethi lo muthi uphakathi kwama-Biguanides afaka isandla ekunciphiseni isisindo sesiguli. Ngasikhathi sinye, isidakamizwa sikaSiofor 850 asigcini nje ngokunciphisa lesi sikhombisi, kodwa futhi sisigcina sisezingeni elifanele isikhathi esithile.
Imisebenzi enjalo ingenzeka ngenxa yokuthi ukwakheka kwayo kufaka ingxenye efana ne-metformin. Kwithebhulethi elilodwa, isilinganiso salo singamamayela ayisishiyagalombili namashumi amahlanu.
Vele, njenganoma yisiphi esinye isidakamizwa, iSiofor 850 ifaka ukubuka umthamo ocacile, kanye nezinye izincomo eziphathelene nokusetshenziswa okufanele komuthi. Banikezwa udokotela ohambelayo, obeka lo muthi ukuthi usetshenziswe yisiguli.
Kungani odokotela bancoma umuthi?
Njengoba wazi, inani eliphakeme likashukela liyingozi kakhulu emzimbeni wawo wonke umuntu. Ngaphezu kwalokho, ayithinti kuphela umsebenzi wezitho zangaphakathi zonke, kodwa futhi inengozi yokubulala impilo yomuntu. Lokhu kungenxa yokuthi amacala amaningi ayaziwa lapho isiguli esinezinkinga zikashukela omkhulu singena ekhefini futhi, ngenxa yalokho, lesi simo saphela ekufeni kwesiguli.
Into ebalulekile enomphumela wokwehlisa ushukela yi-metformin. Nguye othinta ngokufanele zonke izinqubo zomzimba ezifaka isandla ekusetshenzisweni okufanele kwe-glucose kanye nokujwayelekile kwezinga lakhe egazini lesiguli.
Vele, namuhla kunezidakamizwa eziningi ezahlukahlukene ezisetshenziselwa nenhloso eningilizayo. Kodwa lo muthi, ngaphezu komsebenzi ochazwe ngenhla, usiza nesiguli ukwehla isisindo. Yisidakamizwa uSiofor 850 esivame ukubekelwa ukukhuluphala, esivame ukuhambisana nesifundo sikashukela sohlobo 2.
Odokotela batusa ukusebenzisa lo muthi esimweni lapho ukudla okune-kilojoule ephansi kanye nenani elanele lokuzivocavoca kunganikanga umphumela oyifunayo. Kepha akudingeki ucabange ukuthi noma ngubani angaqala ukuthatha la maphilisi, futhi unethemba lokuthi uzoncipha ngokushesha isisindo.
Ithebhulethi ngayinye iqukethe ama-850 mg we-metformin esemqoka esebenzayo. Yileyo kuphela ingxenye yesidakamizwa esiza umzimba ukuthi ubhekane noshukela ophezulu.
Uma isiguli sinokuphikisana nokusetshenziswa kwalo muthi, udokotela angakwazi ukuwufaka komunye umuthi onomphumela ofanayo.
Futhi, isiguli ngasinye singakwazi ukuhlola ngokuzimela ukubuyekezwa kwezinye iziguli ezibuye zawuthatha lo muthi futhi zikhulume ngomuzwa wazo kulokhu.
Isimo sezidakamizwa
Njengoba kushiwo ngenhla, ukwakheka kwalo muthi kuqukethe izakhi eziningana, okungukuthi i-metformin, enikeza umphumela wokwehlisa ushukela.
Kubalulekile futhi ukuthi uqaphele ukuthi lo muthi uw izidakamizwa zokwenziwa, ngakho-ke ngaso sonke isikhathi kufanele unake inhlalakahle yesiguli ezinsukwini zokuqala zokuphuza umuthi. Uma ngemuva kokuthola umthamo wokuqala kungenzeki miphumela emibi, ukwelashwa kungaqhubeka.
Kuyiqiniso, kwezinye izimo, i-metformin ingadala ukonakala okuthe xaxa enhlalakahleni yesiguli. Lokhu kuvame ukwenzeka ezimweni lapho isiguli singahambelani nomthamo ophakanyisiwe, kanye nalapho kukhona izifo ezihambisanayo.
Kwi-Intanethi ungathola izibuyekezo eziningi mayelana neSiofor, emihle nengalungile. Ezingalungile zihambisana neqiniso lokuthi akuzona zonke iziguli ezazi ukuwaqapha kahle amazinga kashukela wegazi, futhi lokhu, kungadala ukuwohloka okubukhali enhlalakahleni. Esikhathini sikashukela, kuyaziwa ukukala amazinga kashukela egazini njalo. Uma lokhu kungenziwa, khona-ke lapho uthatha lesi sidakamizwa, izinga loshukela wegazi lingase lehle kakhulu, ngenxa yalokho umuntu aqala ukukhulisa isimo sokhokho noma isifo sikashukela uqobo.
Ukugwema lezi zimo, kubalulekile ukuqonda ukuthi uwuphuza kanjani umuthi, futhi ngenxa yalokhu kubalulekile ukuhambela odokotela ngesikhathi.
Udokotela kuphela onganikeza isincomo esiphelele sendlela okufanele athathe ngayo ukuze ingalimazi isiguli, kodwa kunalokho isiza ukubuyisela impilo yakhe.
Imiyalo yokusebenzisa amaphilisi
Ngaphambi kokusebenzisa umuthi ekwelapheni isifo sikashukela, kubalulekile ukubonana nodokotela wakho.
Ngesikhathi sokubonisana, i-endocrinologist, icubungula imininingwane etholwe ngesikhathi sokuhlolwa, izonquma umthamo womuthi osetshenzisiwe kanye nohlu lokuphathwa kwawo.
Njenganoma yisiphi esinye isidakamizwa, amaphilisi weSiofor 850 ane-contraindication eminingana.
I-contraindication eyinhloko yile:
- thayipha isifo sikashukela esingu-1;
- izinhlobo ezahlukene zokusabela komzimba, ezingabangelwa yizici eziyingxenye yezimali ezingenhla;
- ukhokho noma ukoma;
- i-acidosis;
- ukwehluleka kwezinso noma kwesibindi;
- izifo ezibangelwa yigciwane noma ukutheleleka kohlobo oluthile;
- izifo zenhliziyo ezisezingeni elibi lokuthuthuka;
- imisebenzi yokuhlinzwa;
- izifo ezingalapheki ezibhebhetheka kakhulu;
- utshwala;
- isiguli esincane;
- abesifazane abancelisa ibele noma abakhulelwe;
- inkambo eyinkimbinkimbi yesifo sikashukela se degree lesibili.
Izinto eziningi eziphikiswa kulula kakhulu ukuzithola, kwanele ukuhlolwa okuthile nguchwepheshe onolwazi. Ngokuphathelene nokusabela komzimba, udinga nje ukuqonda ngqo ukuthi iziphi izakhi eziyingxenye yomuthi othile nokuthi zingawuthinta kanjani umzimba wesiguli. Isakhi esiyinhloko esiyingxenye yalo muthi yi-metformin. Ngakho-ke, ukuqala, isiguli simane nje sazi ukuthi ngabe kukhona okuphathelene nalesi simo.
Ngokusekelwe kulokhu, kulula ukuphetha ngokuthi kungenzeka ukuvikela imiphumela elimazayo emzimbeni umzimba okungenzeka ukuthi i-metformin ibe nayo. Into esemqoka ukwazi ukuthi imiphi imiphumela emibi emzimbeni wayo, nokuthi i-contraindication. Kubalulekile futhi ukuthi uhlolwe ngokuphelele ngesikhathi esifanele futhi uqonde ngezimpawu zomzimba wakho.
Ngendlela, kubalulekile ukuqaphela ukuthi uhla lwalabo umuthi ophethwe kubo lo muthi lubandakanya hhayi izingane kuphela, kodwa kanye neziguli ezindala.
Zingakhombisa nemiphumela emibi eqinile ethinta kabi inhlala-kahle yeguli.
Izindlela zokuvikela ukusetshenziswa komuthi
Odokotela batusa ukuthatha iSiofor 850 ngokuqinile ngokwemiyalo. Kulokhu, kubalulekile ukubheka isimo sesibindi ngaso sonke isikhathi sokwelashwa. Lokhu kwenziwa ngokudlulisa ukuhlaziya okufanele.
Kungenzeka futhi ukuthi udokotela anqume ukuthi uthathe ezinye izidakamizwa ngasikhathi sinye, nazo ezinciphisa ngempumelelo ushukela weziguli. Kuliqiniso, ngudokotela olapha kuphela ongakutshela ngqo ukuthi mangaki amaphilisi omuthi othile ngosuku okudingeka uwaphuze.
Ngaphezu kwalokho, kuyazuzisa ukuzijwayela ngemiyalo yokusebenzisa umuthi ngaphambi kwesikhathi. Imvamisa, isichasiselo siqukethe imininingwane yokuthi ungaphuza kanjani umuthi ngendlela efanele, ukuthi umthamo ungakanani futhi nokuthi ungahlanganiswa naluphi izidakamizwa. Kubalulekile ukukhumbula ukuthi esimweni sokuphathwa kanyekanye kwezidakamizwa ezenza umsebenzi ofanayo, ukwehla okubukhali kakhulu koshukela wegazi kungavunyelwa. Futhi, akufanele sikhohlwe ukuthi ama-analogues weSiofor 850, wona, njengomuthi ongenhla, okuhloswe ngawo ukwehlisa amazinga kashukela egazi. Ngakho-ke, uma uthatha le mishanguzo emibili ngasikhathi sinye, ungavumela ukwehla okubukhali kwalesi sikhombisi, okuholela ekuthuthukiseni ukoma noma okhokho.
Futhi-ke, kubalulekile ngaso sonke isikhathi ukwazi ukuthi umuthi othile uthathwa isikhathi esingakanani, nokuthi imiphi imishanguzo engathathwa ngokufana. Isibonelo, uma usebenzisa kanyekanye imishanguzo ye-sulfonylurea, ungafinyelela esimweni se-hypoglycemia noma ngisho ne-glycemic coma. Ukuze uvikele lokhu, kubalulekile ukukala ushukela wegazi njalo futhi uma kunesidingo thatha lo noma lowo muthi.
Kepha inzuzo eyinhloko ye-metformin, okuyisakhi esiyinhloko seSiofor, ukuthi ayithinti inqubo yokwenziwa kwemvelo kwe-insulin.
Umuthi uwuthinta kanjani umzimba womuntu?
Sekushiwo ngenhla ukuthi yiziphi izimo lapho ungawuthatha khona lo muthi, futhi lapho kungcono ukuwufaka omunye umuthi.
Isinqumo sokuqala ukusebenzisa umuthi ukwelashwa noma ukukhansela ukuqokwa kumele senziwe udokotela oyoya khona ngokwesisekelo sokuhlaziywa okutholakala ngesikhathi kuhlolwa isiguli.
Ukuze uqonde ngokuningiliziwe ukuthi ingasebenza nini, futhi uma kungcono ukwenqaba ukusebenzisa leli khambi, kufanele uqonde ukuthi umuthi uwuthinta kanjani umzimba wesiguli nokuthi usebenza kanjani.
Isenzo somuthi emzimbeni womuntu sihloselwe ukwenza imisebenzi eminingana:
- I-Siofor 800 noma i-850 inomphumela ocindezelayo we-glucose ngokweqile esibindini, futhi futhi ayivumeli inqubo yokuhlukaniswa kwayo nesigcino se-glycogen;
- ithinta kahle inqubo yokuhambisa lo mkhiqizo kuwo wonke izicubu neminyango yomzimba;
- kuvimbela ukufakwa kweglucose ngezindonga zamathumbu;
- yenza izicubu zizwele kakhulu nge-insulin, evumela ukwakheka kwamaselula ukumunca kangcono ushukela, kwehlise izinga layo egazini.
Ngaphezu kwalokho, kubalulekile ukuthi abantu abanesifo sikashukela baqonde ukuthi yiluphi umthamo womuthi ulungile. Kaningi, iziguli zikhathazeka ngombuzo wokuthi kufanele zithathwe kangaki ngosuku, futhi nokuthi zingakanani. Kunombono phakathi kweziguli ukuthi isikhathi eside lapho isiguli sithatha umuthi, kuba ngcono ukusebenza kwawo.
Imvamisa, udokotela uhlala ebeka irejimeni yokwelashwa esekelwe kwizinkomba zesiguli ngasinye, kepha noma kunjalo, imiyalo yokusetshenziswa kwemininingwane yezidakamizwa umthamo kanye nemvamisa yokusetshenziswa kwomuthi.
Umthamo wesidakamizwa unqunywa yi-endocrinologist, oqondiswa yizici zenkambo yesifo, ushukela kanye nezinkomba ngazinye zokuphila kahle kwesiguli.
Ukuhlanganiswa kweSiofor nezinye izidakamizwa, ukubuyekeza ngakho nangezindleko zayo
Kwashiwo ngenhla ukuthi umuthi uSiofor 850 ungahlanganiswa neminye imithi.
Uma kunesidingo, noma yisiphi isiguli singaphuza umuthi ngokuhlangana neminye imithi.
Ngaphambi kokusebenzisa iSiofor njengengxenye ngesikhathi sokwelashwa okuxubile, kufanele uthintane nodokotela wakho ngokushintsha imithamo yemithi.
Ngokuvamile, umuthi uSiofor 850 uhlanganiswa ne:
- noma yimuphi umuthi we-insulin;
- i-ejenti ehlose ukunciphisa i-adsorption emathunjini;
- inhibitor;
- sulfanylurea;
- nguyenkungu.
Ngezindleko uSiofor usezingeni eliphakathi nendawo. Kumakhemisi, intengo yeSiofor 850 kuyaqabukela idlula amakhulu amane ama-ruble. Kepha kungaba phezulu noma phansi, kuya ngokuthi ngubani owenza lo muthi, kanye nesifunda lapho lo muthi uthengiswa khona eRussia.
Kumele ngisho ukuthi cishe konke ukubukezwa kokusetshenziswa kwethuluzi kulungile. Uma isiguli sinesifo sikashukela sohlobo lwe-2 ngempela, futhi singekho esigabeni esinzima sesifundo, khona-ke umphumela omuhle wohlelo luqala kakade ngeviki lesibili lokwelashwa. Kuzo zonke ezinye izimo, udinga ukubonana nodokotela ukuze uthole izeluleko ezengeziwe.
Uma ikhambi lingasifanele isiguli, khona-ke angazizwa ikhanda elibuhlungu, isiyezi, ukugabha, isicanucanu nezinye izimpawu.
Isazi esivela kuvidiyo ekulesi sihloko sizositshela ngomthelela weSiofor emzimbeni wesifo sikashukela.