Abaningi banesifiso sendlela yokuthatha uSiofor? Lesi sidakamizwa esingeqembu le-Biguanide. Isetshenziselwa ukulawula ukugxila kwe-glucose kuma-diabetics kwifomu elizimele lesifo, lapho ukusebenza ngokomzimba nokudla okhethekile kungakwazi ukubekezelela i-glycemia. Ngaphezu kwalokho, umuthi uSiofor unciphisa i-cholesterol futhi ususe amakhilogremu angeziwe.
I-Siofor isidakamizwa esidumile se-hypoglycemic sosithako sayo esisebenzayo yi-metformin. Le ndatshana izokusiza ukuthi ufunde kabanzi ngokuthi umuthi usebenza kanjani, uthole ukuthi uwusebenzisa kanjani ngendlela efanele.
Izici ze-pharmacological zomuthi
Umuthi weSiofor ukhiqizwa yinkampani yezokwelapha iBerlin-Chemie AG, eyingxenye yenhlangano enkulu kunazo zonke yase-Italy - Menarini Group. Umuthi uyatholakala ngefomu lethebhulethi - iSiofor 500, 850 ne-1000 mg.
Njengoba kushiwo ngaphambili, i-metformin iyingxenye esebenzayo yesidakamizwa uSiofor. Akuthinti ukusebenza kwamaseli we-beta, ngakho-ke i-insulin ayakhiqizwa ngokweqile futhi ayiholeli ku-hypoglycemia. Ngaphezu kwakho, umuthi uqukethe inani elincane lezinye izakhi - i-povidone, i-magnesium stearate, hypromelase, titanium dioxide (E 171) ne-macrogol 6000.
Ngenxa yesakhi esisebenzayo, ukuthatha uSiofor kukuvumela ukuthi uzuze imiphumela elandelayo:
- Yehlisa ukufakwa kweglucose emgodini wokugaya ukudla.
- Yehlisa inqubo yokukhiqiza ushukela ngesibindi.
- Thuthukisa ukuthikamezeka kwezicubu ezitholakala kwi-hormone enciphisa ushukela.
Ngaphezu kwalokho, iSiofor kwisifo sikashukela inomphumela onenzuzo we-lipid metabolism futhi ithuthukisa ukuqina kwegazi. Iyanciphisa ukugxilisa ushukela hhayi kuphela ngemuva kokudla, kodwa futhi nesisu esingenalutho.
Isiguli sithatha umuthi futhi sinamathela ekudleni okukhethekile sizokwazi ukufeza ukwehliswa kwesisindo somzimba ngokweqile.
Umthamo wezidakamizwa
Udokotela angagunyaza ukusetshenziswa kwalesi sidakamizwa ekwelapheni isifo sikashukela sohlobo 2, ikakhulukazi lapho sihlangana nokudla ngokweqile kanye nokudla okungenampilo. Umthamo wesidakamizwa unqunywa ngudokotela ohambelayo, onaka amazinga kashukela kanye nesimo esivamile sesiguli.
Umthamo wokuqala weSiofor usukela ku-500 uye ku-1000 mg ngosuku, khona-ke imithamo ikhuphuka kancane kancane ngokuhamba kwesonto elilodwa. Umthamo omaphakathi nsuku zonke uhla kusuka ku-1500 kuya ku-1700 mg. Umthamo omkhulu wansuku zonke yi-3000 mg.
Amacwecwe adliwa ngesikhathi sokudla, ungahlafunisi futhi uphuze ngamanzi. Uma kufanele uthathe amaphilisi ama-2-3 ngosuku, kungcono ukuphuza umuthi amahlandla amaningana - ekuseni nakusihlwa.
Kumele kuqashelwe ukuthi ukusetshenziswa okuzimele kwethuluzi kungadala imiphumela emibi. Udokotela kuphela okwazi ukuthuthukisa uhlobo lokwelashwa okufanele isiguli silunamathele. Ngaphezu kwalokho, umuthi ungathengwa ekhemisi kuphela ngomuthi odingekayo.
Isidakamizwa uSiofor sidinga ukugcinwa singatholakali ezinganeni ngamazinga okushisa asekamelweni.
Ngemuva kosuku lokuphelelwa yisikhathi, okuyiminyaka engu-3, ukusetshenziswa komuthi akuvunyelwe.
Contraindication kanye nomonakalo ongaba khona
Njengezinye izidakamizwa eziningi, ukusetshenziswa kweSiofor kungahle kungavunyelwe nakancane kwabanye abanesifo sikashukela.
Lo muthi uqukethe uhlu olukhulu lwe-contraindication okufanele lubhekwe lapho kudwetshwa irekhodi lokwelashwa. Lokhu kufaka phakathi:
- isifo sikashukela esincike ku-insulin;
- ukuqeda ngokuphelele ukukhiqizwa kwe-insulin ngohlobo 2 sikashukela;
- isifo sikashukela kanye ne-coma, i-ketoacidosis (isifo se-metabolic);
- ukungasebenzi kwesibindi kanye / noma ukungasebenzi kwezinso;
- ukwehluleka kwenhliziyo kanye ne-myocardial infarction;
- ukwehluleka kokuphefumula kanye ne-pathology yamaphaphu;
- inkambo yezifo ezinzima ezithathelanayo;
- isimo se-catabolic, ngokwesibonelo isimila;
- ukungenelela kokuhlinzwa, ukulimala;
- i-hypoxia;
- i-lactic acidosis (kufaka phakathi umlando);
- ukuthuthukiswa kophuzo oludakayo;
- isikhathi sokuzala ingane;
- ukuncelisa;
- Ukudla okunama-khalori aphansi (ngaphansi kuka-kcal we-1000 ngosuku);
- izingane ezingaphansi kweminyaka engu-18;
- ukuzwela komuntu ngamunye kwizakhi.
Uma isetshenziswe ngendlela engafanele, esikhundleni sokuthi ibe nomthelela omuhle emzimbeni, izokwenza ngokungalungile. Izindlela ezinkulu zokusabela ezingezinhle yilezi:
- Ukuphazamiseka kokugaya ukudla, okubonakala kobuhlungu besisu, uhudo, ushintsho ekunambithekeni, ekuhlanzeni, ekunciphiseni isisindo.
- Ukuphazamiseka emsebenzini we-hematopoiesis - megablastic anemia (ukwephulwa kokuhlanganiswa kwe-DNA kanye nokuntuleka kwe-folic acid emzimbeni).
- Ukungezwani komzimba esikhunjeni.
Uma isiguli sizwa okungenani esisodwa salezi zimpawu, kungadingeka siphazamise ukwelashwa. Esimweni lapho isiguli sithatha inani elikhulu lomuthi kunelidingekayo, singathola izimpawu zokweqisa:
- ukuthuthukiswa kwe-lactic acidosis;
- i-hypoglycemia;
- ukujuluka ngokweqile;
- ukuzindla kwenhliziyo;
- ukuthuthumela
- isimo sokufikelwa amandla;
- umuzwa wendlala.
Uma isiguli sine-overdose efomu emnene futhi sazi, sidinga ukudla okuqukethe ama-carbohydrate noshukela (ucezu kashukela, ujusi omnandi, uswidi). Ngokulahlekelwa ukwazi, isiguli sifakwa nge-40% glucose solution emthanjeni.
Ngemuva kokuthuthukisa isimo sakhe, isiguli sinikezwa ukudla okugcwele ama-carbohydrate ukuvimbela ukukhula kwe-hypoglycemia futhi.
Iziphakamiso lapho usebenzisa uSiofor
Abaningi bakholelwa enganekwaneni yokuthi ukusebenzisa lesi sidakamizwa ngaphandle kwemizamo kuzosiza ukuqeda i-hyperglycemia namaphawundi angeziwe. Eqinisweni, lokhu kukude nalokhu.
Isifo sikashukela yisifo esikhohlisayo kakhulu, okungekho khona ophilisayo “wephilisi lesimanga”. Ekwelashweni kwe-pathology, udinga ukubekezela futhi uqine, ngoba ukulungiswa ngempumelelo kwezinga leshukela elijwayelekile kuncike:
- Ukudla okukhethekile.
- Umsebenzi womzimba.
- Ukwelashwa kwezidakamizwa.
- Ukulawulwa okuvamile kwe-glycemic.
Abantu abanesifo sikashukela kufanele banamathele ekudla okufanele. Iqeda ukusetshenziswa kokudla okunamafutha nokudla okuqukethe ama-carbohydrate egaya kanye noshukela. Esikhundleni salokho, udinga ukufaka izithelo ezingafakiwe, imifino, umkhiqizo wobisi olunoshukela omuncu (i-kefir, ukhilimu omuncu, ubisi olubilisiwe olubisiwe) ekudleni.
Indlela yokuphila esebenzayo yisihluthulelo sempilo ende nasekwelapheni izifo eziningi. Njengoba unesifo sikashukela, kubalulekile kakhulu ukugcina umzimba wakho usisindo esijwayelekile. Ukuze wenze lokhu, okungenani udinga ukunikela okungenani imizuzu engama-30 ngosuku ukuhamba ngezinyawo. Ngaphezu kwalokho, kunconywa ukwenza ukugijimela, i-yoga, ukudlala imidlalo, ngokuvamile, okufiswa ngumuntu umphefumulo.
Kwesinye isikhathi ngokwenziwa kwesifo sikashukela sohlobo 2 ezigabeni zokuqala, kungenzeka ukwenza ngaphandle kwezidakamizwa. Uma kunesidingo sokusetshenziswa kwemithi, isiguli kufanele silandele zonke izincomo zochwepheshe zokwelapha.
Futhi-ke, udinga ukubheka izinga lakho likashukela nsuku zonke. Abantu abanesifo sikashukela "abanesipiliyoni" bavame ukuba nedivayisi - i-glucometer, ekala ngokushesha ukugxilwa koshukela egazini. Ngo-2 isifo sikashukela, ukuhlolwa kufanele kwenziwe okungenani kaningana ngosuku - esiswini esingenalutho kanye / noma ngemuva kokudla, kanye nasebusuku.
Ngesikhathi sokwelashwa kwesifo sikashukela, utshwala kufanele bungabandakanywa. Ngisho nesiphuzo esilula kakhulu singathinta amazinga kashukela. Kungale ndlela kuphela, ulandela umthetho ngamunye, ungathola umphumela wangempela, ugweme imiphumela emibi yesifo futhi ulahlekelwe ngisho namaphawundi ambalwa angeziwe.
Ukuxhumana neminye imithi
Ukuthatha iSiofor kanye nezinye izidakamizwa kungathinta umphumela wayo wokwelapha. Kwezinye izimo, ukwanda okusheshayo kwamazinga kashukela kungenzeka, futhi kwesinye, ukwehla okubukhali.
Ngokuqapha, kufanele uthathe inkambo yokuthatha nokuphuza amaphilisi weSiofor nge-cimetidine, ama-anticoagulants angaqondile kanye ne-ethanol. Umuthi othathwe nale mishanguzo ungadala izinkinga ezinkulu kakhulu, ngokwesibonelo, isimo se-hypoglycemia noma i-lactic acidosis.
Ukwanda kwesenzo se-hypoglycemic kudala ukusetshenziswa kwalokhu okubili:
- ngama-ejenti we-hypoglycemic;
- ngama-salicylates;
- nabavimbeli be-beta;
- nge-mao ne-ACE inhibitors;
- nge-oxytetracycline.
Izidakamizwa ezinjalo zehlisa umphumela wokwehlisa ushukela wesidakamizwa:
- glucocorticoids;
- izindlela zokuvimbela inzalo ngomlomo (isb., Regulon);
- okuphuma ku-phenothiazine ne-diuretics;
- ama-hormone egilo;
- dericatives ye-nicotinic acid;
- ama-audiathomimetics.
Ngaphezu kwalokho, umbuzo uvame ukuphakama phakathi kweziguli: kungenzeka yini ukuthatha uSiofor no-Orsoten futhi wenze lokhu? Emiyalweni enamathiselwe yesidakamizwa ukuze wehlise isisindo, u-Orsoten uthi ingasetshenziswa ngokuhlangana nama-hypoglycemic agents kwesifo sikashukela sohlobo 2. Kepha umuthi i-Torvakard ene-Siofor kufanele usetshenziswe ngokucophelela okukhulu.
Enye yezinto eziphikiswa yiRegulon yokuvimbela inzalo isifo sikashukela. Kwi-Intanethi ungathola ukubuyekezwa kweziguli ukuthi uRegulon uyakwazi ukwehlisa isisindo ngokweqile. Eqinisweni, uRegulon ngamaphilisi okulawula ukuzalwa, hhayi umuthi wokunciphisa umzimba. Enye yezenzo ezithile zomuthi ukwehla kwesisindo okuncane.
Futhi-ke, iSiofor isidakamizwa esihle ukwehlisa ushukela wegazi. Iguqula izinqubo emzimbeni ezihambisana nokumuncwa nokukhiqizwa kweglucose. Umuthi ovunyelwe udokotela kumele udliwe, uqaphela yonke imithetho. Ngeshwa, azikho izidakamizwa ngaphandle kokuphendula okungathandeki. Uma kukhona ama-contraindication noma imiphumela emibi, kungadingeka ukuthi ukhansele ikhambi. Noma kunjalo, iningi labanesifo sikashukela bahlala benelisekile ngomphumela womuthi, futhi bawusebenza njengosebenza ngempela. Ividiyo ekulesi sihloko izokusiza ekutholeni isifo sikashukela futhi uqale ukwelashwa ezigabeni zokuqala.
