Ama-Siofor for diabetesics - izici nemithetho yokuphuza umuthi

Abantu abanesifo sikashukela i-mellitus yemikhakha ehlukahlukene kanye namafomu, anqunywe yi-Siofor, azibuza ukuthi uwuthatha kanjani umuthi nokuthi unikeza muphi usizo. USiofor ungowesigaba sama-biguanides wesimanje. Kubekelwe ukulawulwa okusebenzayo kwenani lama-glucose agxilisiwe kuma-diabetesics ancike ku-insulin.

Ithuluzi libaluleke kakhulu uma ukudla okufanele nokuvivinya umzimba njalo kungasizi ekulweni ne-glycemia ekhulisa isisindo. Inzuzo ebaluleke ngokulinganayo yomuthi amandla ayo okunciphisa kahle i-cholesterol, futhi inikeza usizo oluhlukile ekulweni namafutha ngokweqile.

ISiofor ingesinye sezidakamizwa esidumile se-hypoglycemic. Isithako saso esisebenzayo kakhulu yi-izidakamizwa metformin. Le ndatshana inethuba lokutadisha ngokuningiliziwe umbuzo wokuthi umuthi uwuthinta kanjani umzimba womuntu ogulayo, uwuphuza ngendlela efanele kanjani.

Izici ze-Pharmacological

ISiofor ingumkhiqizo ovela eBerlin-Hemi AG. Lokhu kungenye yezinhlangano ezinkulu zemithi ezise-Italy. Umuthi ukhiqizwa ngendlela yamacwecwe emithamo ehlukene. Kungaba yiSiofor ku-500, 850 naku-1000 mg.

Into esemqoka yesidakamizwa ayithinti ukusebenza kwamaseli we-beta womuntu. Ngenxa yalokhu, inani elikhulu le-insulin alakhiqizwa emzimbeni, ngenxa yalokho i-hypoglycemia ayikhuli.

Ukwakheka okungafani kwalesi sidakamizwa kuvumela abantu abaphuzayo ukuthi bathole imiphumela emihle efana nale:

1. Ukunciphisa ukumuncwa kwe-glucose esebenzayo ezithweni zokugaya;
2. Yehla ngezinga lokukhiqizwa koshukela esibindini;
3. Ukwenza ngcono ukuzwela okuphelele kwezicubu ezixakile kuma-hormone aqukethe ushukela.

I-Siofor ekwelapheni isifo sikashukela inomphumela omuhle ku-lipid metabolism ephelele, ukuqiniswa kokuhlanganiswa kwegazi kuthuthukiswa kakhulu. Inani ushukela emzimbeni liyancipha ngesikhathi sokudla, kodwa futhi nangaphambi kokudla.

Umphumela oyinhloko wesidakamizwa

ISiofor, esigabeni sayo, ingeyama-Biguanides, njengoba ibonakala ngomphumela oyingqayizivele we-antihyperglycemic. Ukusetshenziswa njalo nangendlela efanele kwemithi kudala ukwehla kwenani eliphelele le-glucose yemvelo esegazini lesiguli.

Ithuluzi alikukhuthazi ukukhiqizwa kwe-insulin yemvelo futhi alinegalelo ekwakhiweni kwe-hypoglycemia.

Umphumela omuhle omuhle we-Siofor ususelwa kunqubo ethile:

1. Ukwehla ekukhiqizeni ushukela ophelele esibindini ngenxa yokuvinjwa okuphelele kwezinqubo ezinjenge-gluconeogenesis ne-glycogenolysis.
2. Ukwanda okuphakeme kuzinga eliphelele lokuzwela kwezicubu zomuntu kwi-insulin yemvelo. Ngenxa yalokhu, inqubo yokumuncwa kanye nokukhishwa okulandelayo kweshukela kuwo wonke izicubu zomzimba kukhula kakhulu.
3. Ukuvinjwa okuphelele kokufakwa kweshukela noshukela egazini.

Into esemqoka yeSiofor inethonya ku-glycogen synthetase, ngenxa yalokhu, ukukhiqizwa kwe-glycogen yemvelo kuyakhuthaza. Umthamo wezinto zokuhamba uwonke wamaprotheni we-glucose athuthukisiwe uyakhuphuka.

Umuthi uthinta kahle inqubo ejwayelekile ye-lipid emzimbeni, noma ngabe uthinta muphi inani leshukela. Lokhu kunciphisa ngokuzenzakalelayo ukuqoqwa kwe-cholesterol ephansi yokulimaza kanye nenani eliphelele lama-triglycerides.

Ubufakazi obukhulu beSiofor

Inhloso eyinhloko yesidakamizwa ukwelashwa okusebenzayo kwesifo sikashukela sohlobo 2. Ibekelwe iziguli ezinalesi sifo futhi ngasikhathi sinye esinesisindo esithe xaxa.

Kubantu abadala, ukwelashwa kubekwe ngendlela ye-monotherapy, kusetshenziselwa ukwakheka okuthile namanye ama-hypoglycemic agents namuhla kanye ne-insulin.

Umthamo weSiofor

Odokotela banquma umuthi ekwelapheni isifo sikashukela sohlobo 2. Ikhambi liyasebenza uma lesi sifo sihambisana nesiguli esikhulu ngokweqile, uma ukudla okuhleliwe kungasebenzi.

Umthamo womuthi unganqunywa futhi unqunywe kuphela uchwepheshe. Udokotela ubheka inani ushukela osegazini, kanye nenhlala-kahle yeziguli ezinesifo sikashukela.

Nayi imithetho eyisisekelo yomthamo:

• Umthamo wokuqala wesidakamizwa ngu-500-1000 mg ngosuku;
• Ngesikhathi sokwelashwa, umthamo uyanda masonto onke;
• Umthamo ojwayelekile wansuku zonke ungafinyelela ku-1300-1700 mg;
• Isilinganiso esiphezulu somuthi osithathiwe yi-3000 mg.

Umuthi usetshenziswa ngesikhathi sokudla, amaphilisi awabhungwa bese egezwa ngamanzi amaningi. Uma udokotela eyalele ukuthi athathe amaphilisi ama-2-3 ngosuku, kufanelekile ukuwahlukanisa wonke umthamo kumthamo eziningana - kungakuhle ukuwaphuza kusihlwa nasekuseni.

Udokotela kuphela ongabheka uhlobo olusebenza kahle kakhulu lokwelashwa kanye nomthamo, futhi ubhala incwadi yokuthenga amaphilisi ekhemisi. Konke okudingwa yisiguli ukunamathela ezinconyelweni zezokwelapha.

Umkhiqizo kumele ugcinwe kude nezingane. Izinga lokushisa kumele libe lokushisa lasekamelweni. Ezimweni ezinjalo, umuthi ugcinwa iminyaka emithathu, emva kwalokho wenqatshelwe ngokuphelele ukuthatha umuthi.

I-contraindication esemqoka

Njengazo zonke izidakamizwa, uSiofor unokuphulwa okuthile. Kumele zibhekwe ngudokotela lapho ethuthukisa ukwelashwa okwelaphayo.

Umuthi awubekelwe abantu abanesifo sikashukela kulezi zimo ezilandelayo:

• Ifomu lesifo sikashukela esincike ku-insulin;
• Ukumisa ukukhiqizwa kwe-insulin lapho kunesifo sohlobo lwesibili;
• Ukuthuthukiswa kwesifo sikashukela nokhokho, kanye nokuba khona kwe-ketoacidosis, okungukuthi, ukuphazamiseka komzimba;
• Ukusebenza kahle kwezinso nezinso;
• Ukwehluleka kwenhliziyo kanye nesimo sangaphambi kokuqamba;
• Ukwehluleka kokuphefumula kanye nezimo ezahlukahlukene ze-pathological zohlelo lokuphefumula;
• Isimo esisebenzayo sezifo eziyinkimbinkimbi zezifo;
• Ama-tumors kanye nesimo se-catabolic;
• I-hypoxia eyingozi;
• Ukuhlinzwa nokulimala;
• Ukudla okuphansi kwekhalori;
• Izingane ezingaphansi kweminyaka engu-18;
• Uphuzo oludakayo;
• Ukungabekezelelani komuntu ngamunye ezintweni eziphambili zokwahlulela.

Ngesikhathi esifanayo njenge-contraindication, ukuthatha uSiofor kungadala ukusabela okuhlukahlukene. Ukuyeka ukuphuza umuthi noma ukunciphisa umthamo obekiwe kuzodingeka uma kunezimpawu ezinjengokuthi:

1. Ukugaya ukudla okucasulayo kanye ne-gastrointestinal. Lokhu kungaba yibuhlungu besisu esibuhlungu, isifo sohudo esivamile, ukuphazamiseka kokunambitha, ukuhlanza okuqothulayo kanye nokunciphisa umzimba ngokushesha;
2. Ukweqa ohlelweni lwe-hematopoietic;
3. Ukuvela kokuphendula kwesikhumba kwe-allergic.

Ngokuvela kwalezi zimo njengokujuluka kokujuluka, ukwakheka kokuqhaqhazela, umuzwa oshubile wendlala, ubuthakathaka, nokufoka amandla, umuntu angahlulela ukweqisa okungenzeka. Uma isiguli sihlala siqaphile, kuzodingeka simnikeze ukudla ngokuqukethwe okunama-carbohydrate amaningi ukuze agcwalise igazi nge-glucose.

Uma isiguli sesilahlekelwe yingqondo, isixazululo se-glucose esingu-40% siphathwa ngaphakathi. Ngemuva kokudambisa ukungezelela, isiguli sinikezwa ukudla isikhashana, sicebile emakhabhathini asheshayo. Lokhu kuzovimbela ukuthuthukiswa kwe-hypoglycemia enkulu.

Ukukhulelwa nokukhulelwa

I-Siofor i-contraindified ngokuphelele ngesikhathi sokukhulelwa nokuncelisa. Owesifazane ophethwe uhlobo lwesibili sikashukela kufanele axwayiswe ngokubaluleka kokwazisa uchwepheshe ozobakhona uma ekhulelwe engahlelile. Kulesi simo, umuthi ukhanseliwe ngokuphelele futhi ushintshwa nolunye uhlobo lokwelashwa kwe-insulin.

Lokhu kuzosiza ukwenza ngokwejwayelekile izinga lokuhlushwa kwe-glucose emzimbeni ngaphandle kokusebenzisa iSiofor. Indlela enjalo izosiza ekunciphiseni ubungozi bokuqhamuka namaphutha e-pathological ahlukahlukene ngenxa yemiphumela ye-hyperglycemia.

Ngokuya ngocwaningo, into esemqoka yesidakamizwa inamandla okungena ebisini lezilwane ezixhashazayo. Lesi sifaniso senziwa futhi kumuntu, ngesisekelo lapho udokotela engahambeli uSiofor ngesikhathi sokuqunjelwa.

Incomo eyisisekelo yokusetshenziswa

Eduze nomuthi uSiofor, kwaba nombono oyiphutha wokuthi ukusetshenziswa kwalesi sidakamizwa kuzosiza ukuqeda isisindo ngokweqile kanye ne-hyperclycemia ngaphandle kwemizamo. Lona umbono onephutha. Zonke iziguli ezinesifo sikashukela kufanele ziqonde ukuthi lesi yisifo esikhohlisayo, asinalo iphilisi elimangalisayo. Ngenqubo yokwelashwa, udinga ukubekezela ekubekezeleni okuthile.

Phakathi kwazo kukhona:

1. Ukugcinwa okuphoqelekile kokudla okukhethekile;
2. Imithwalo ejwayelekile;
3. Ukwelashwa kwezidakamizwa okuhambisanayo;
4. Ukulawulwa njalo phezu kwezinga le-glycemia.

Abantu abanesifo sikashukela kufanele badle kahle. Lokhu kungabandakanywa kokudla okunamafutha nokudla okuqukethe ama-carbohydrate asheshayo, anokugaya kalula nge-glucose. Ukudla kwansuku zonke kufanele kugcwaliswe ngenani elikhulu lemifino, izithelo eziningi, imikhiqizo yobisi yokuqukethwe kwamafutha aphansi.

Ukusetshenziswa kweSiofor kumele kuhambisane nendlela yokuphila esebenzayo. Lesi isiqinisekiso esiqinisekisiwe sokuphila isikhathi eside kanye nokwelashwa kwezifo eziningi, isifo sikashukela, kubandakanya.

Impumelelo yokwelashwa imvamisa isuselwa ngokuqondile ekusekelweni komzimba wakho kwesisindo esamukelekayo esamukelekayo. Ukuthola umphumela onjalo, kufanele ufake ohlelweni lwansuku zonke, uma kungenjalo ukuvakasha ejimini, okulungele, kodwa okungenani imizuzu engama-30 yokuhamba. Kunconywe kakhulu ukuthi wenze i-yoga, ukugijimela, umdanso kanye nemidlalo. Wonke umuntu angazikhethela inketho engcono kakhulu yokusebenza komzimba, into esemqoka ukuthi kunjalo.

Ehlelweni lokuthuthukisa isigaba sokuqala sesigaba sesibili sikashukela, kungenzeka ngokuphelele ukwenza ngaphandle kokusebenzisa ezinye izidakamizwa. Uma kunesidingo sazo, isiguli sidinga ukuthatha kuphela lezo zimali ezibekwe uchwepheshe futhi kumthamo ochazwe kuye ngqo.

Futhi ngesikhathi senqubo yokwelashwa, kuyadingeka ukuthi uhlole izinga le-glucose emzimbeni wakho njalo ngangokunokwenzeka. Abaningi besifo sikashukela manje bane-divaysi ekhethekile nabo - i-glucometer. Idivaysi iyakwazi ukukala ngokushesha futhi ikhombise ukugxila kanye nenani loshukela egazini. Ohlelweni lwesibili lwesifo sikashukela, isheke kufanele lenziwe kaningana ngosuku.

Kungcono ukwenza le nqubo ekuseni nasebusuku, ngemuva kokudla nesisu esingenalutho.

Uma ulandela imiyalo engenhla futhi ulandela ngokucophelela umthetho ngamunye ngesikhathi sokwelashwa ngeSiofor, ungafinyelela ngokushesha umphumela omuhle ekwelashweni kwesifo sikashukela. Leli yithuba elihle lokugwema imiphumela emibi ebangelwa yilesi sifo futhi ngokushesha ususe ezimbalwa ezithole amaphawundi angeziwe.

Ukusebenzelana kwezidakamizwa

Ukuthatha umuthi uSiofor ngasikhathi sinye neminye imishanguzo kungadala ushintsho emiphumeleni yawo ebalulekile yokwelapha. Ezimweni ezithile, kunengozi yokwanda kwesilinganiso se-glucose, ngaphandle kwalokho ungahlangabezana nokuncipha kwe-glucose.

Ngokucophelela udinga ukusebenzisa uSiofor nge-cimetidine, ethanol kanye nama-anticoagulants anamuhla. Ukusetshenziswa kanyekanye komuthi uSiofor ngale mishanguzo kuholela ezinkingeni, phakathi lapho ukuthuthukiswa kwe-hypoglycemia okuyingozi kungahlukaniswa khona, kunobungozi be-lactic acidosis.

Ukwanda okukhulu komphumela omubi we-hypoglycemic uyakwazi ukudala ukusetshenziswa kweSiofor ngasikhathi sinye ngezigaba ezilandelayo:

• Ukwehlisa ushukela;
• Ama-salicylates;
• Beta-blockers;
• Ama-inhibitors wesimanjemanje we-MAO ne-ACE;
• I-Oscitetracycline.

Ngokunciphisa kunciphisa inani nezinga loshukela emzimbeni wesifo sikashukela sithatha iSiofor ngemithi efana nale:

1. Glucocorticoids;
2. Izindlela zokuvimbela inzalo zomlomo zesimanje;
3. Zonke izinhlobo ezingenzeka ze-phenothiazine ne-diuretics yokwelapha;
4. Ama-hormone okwakha umzimba ukuze kugcinwe ukusebenza kwe-thyroid;
5. I-Nicotinic acid kanye nama-analogues ayo;
6. I-Sympathomimetics.

Kwabanesifo sikashukela abaningi, umbuzo ngezikhathi ezithile uphakama ukuthi kuvunyelwe yini ukuthatha amaphilisi. Siofor ngasikhathi sinye no-Orsoten.

Imiyalo esemthethweni yesidakamizwa ehloselwe ukunciphisa isisindo ibonisa ukuthi kuvunyelwe ukuyisebenzisa ngasikhathi sinye nemithi esebenzayo ye-hypoglycemic uma kwenzeka ukuqhubeka kokuthuthuka kohlobo lwesibili sikashukela. Kudinga ukubonisana nodokotela ngaphambili kanye nokuhambisana nezincomo zakhe.

Imiyalo ekhethekile yokusebenzisa umuthi

ISiofor ibonakala ngekhono lokudala into efana ne-lactic acidosis. Lesi yisimo esibi kakhulu sokubi, esivelakancane. Kuhlobene ngqo nokuqongelwa kwenani elikhulu le-lactic acid yemvelo egazini, okuvela ngesisekelo sokuqalwa kwe-metformin.

Iningi lamacala okuvela nokukhula kwe-lactic acidosis eyingozi kulabo abathola uSiofor babebonwa ezigulini ezinesifo sikashukela ngasikhathi sinye ukwehluleka kwezinso.

Ukuvimbela okuyinhloko kwe-lactic acidosis ephikisayo ukukhonjwa kwezinto eziningi eziyingozi zezinkinga - i-ketosis, isifo sikashukela, ukwenqatshelwa kokudla isikhathi eside, ukuphuza utshwala ngokweqile, ukwehluleka kwesibindi okungapheli kanye nakho konke ukubonakaliswa kwe-hypoxia.

Ngesizathu sokuthi into esemqoka yeSiofor idalulwe yi-genitourinary system, kuyadingeka ukuthola inani le-creatinine epulini yegazi. Lokhu akumele kwenziwe hhayi ngaphambi kokwelashwa kuphela, kodwa ngokuvama okuphezulu ngesikhathi sokwelashwa konke.

Ukuqapha kufanele kusetshenziswe ezimweni zomsebenzi we-renal ongasebenzi kahle ekuqaleni kokwelashwa, kususelwa ekusetshenzisweni kwemithi yesimanje ye-antihypertensive, ama-diuretics, noma izidakamizwa ezahlukahlukene ezingezona ze-antiidal. Uma ukubonakaliswa okubukhali kwe-lactic acidosis kwenzeka, iSiofor idinga ukushintshwa namanye ama-hypoglycemic agents afanayo. Lokhu kungaba uhlobo olujwayelekile lwe-insulin.

Futhi, amaphilisi awafakwa ngokuphelele ezinsukwini ezimbili ngaphambi kwe-MRI nangemva kwalokho, ikakhulukazi uma kungeniswa ukwehlukaniswa okuqukethe iodine okukhethekile.

Ukwemukelwa kukaSiofor kumiswa ezinsukwini ezimbili ngaphambi kokuhlinzwa okuhleliwe, okwenziwa ngaphansi kwe-anesthesia ejwayelekile, kanye nalapho kufakwa isithombe sokuqaqambisa umgogodla noma isifo sokuqaqamba kwamalunga. Ukwelashwa kungaqhubeka ngemuva kokuqala kabusha komsoco noma ezinsukwini ezimbili ngemuva kokuhlinzwa. Kulokhu, udokotela nakanjani uzokunaka ukulengiswa kwezinso.

Iziguli ezinikezwe uSiofor kufanele zazi ukuthi umuthi awunakungena esikhundleni sokudla nokuzivocavoca nsuku zonke. Lezi zindlela zokwelapha kumele zihlanganiswe nokusetshenziswa kwezidakamizwa, kulandela izincomo nezeluleko zikadokotela. Ngesikhathi sokulashwa neSiofor, iziguli zidinga ukunamathela ekudleni okukhethekile kokudla, kubalulekile ukugcina inani elithile lama-carbohydrate usuku lonke. Uma iziguli zinesisindo somzimba ngokweqile, indlela yokudla kufanele ilandelwe.

Iziguli, noma ngabe zinjani uhlobo lwe-pathology, izinga lokukhula kwesifo sikashukela kanye nesisindo sesiguli, kufanele lenze izifundo ezikhethekile, zivivinye.

Udinga ukwazi ukuthi ukungena kahle kwamatafula weSiofor akubangeli ukuthuthukiswa kwe-hypoglycemia, ngakho-ke, akukuthinti ikhono eliphelele nekhwalithi yokulawulwa kwezimoto zesimanje. Awukho umthelela kwikhwalithi yemisebenzi ehambisana nezinqubo eziyinkimbinkimbi zokuhlinzeka ngezinsiza.

Uma umuthi usetshenziswa ngasikhathi sinye namanye ama-hypoglycemic agents - i-insulin ne-repaglinide - kunengozi yokuthola ukuthuthukiswa kokuhlukunyezwa kwe-hypoglycemic. Kuzodinga ukuqapha okwedlulele kwinqubo yokushayela izimoto zesimanje. Ukunakekelwa kuyadingeka ezinhlotsheni ezinobungozi zemisebenzi yomsebenzi, lapho kudingeka khona ukunakwa okuninginingi kokubhekisisa nokushesha kokuphendula kwengqondo.

I-Siofor - intengo nokubuyekezwa

ISiofor, intengo yayo engabizi kakhulu, ithengiswa ngomuthi kumakhemisi ajwayelekile. Izindleko zincike kumthamo wezidakamizwa futhi zisukela kuma-ruble angama-250 kuye kwangama-420. Ukubuyekezwa kwezidakamizwa uSiofor kunethiwekhi kuqoqa kuphela okuhle. Uma umuthi uphuzwe ngokuhambisana nemibandela nezincomo zikadokotela oholayo, unikeza umphumela omuhle ohlukile.

Nazi ezinye izibonelo zobufakazi obuvela kubantu abaphathwe uSiofor.

Isiphetho

I-Siofor umuthi wanamuhla oyingqayizivele okuhloswe ngawo ukunciphisa inani nokuhlushwa ushukela egazini. Ikwenza kube ngokwejwayelekile izinqubo zemvelo eziyisisekelo emzimbeni womuntu, ngokususelwa ekucasheni nasekukhiqizweni kwemvelo kweglucose.

Umphumela omuhle ungatholakala uma usebenzisa umuthi ekuncomeni kadokotela futhi ulandele izincomo zawo ngokuqinile. Lapho kukhona ukungqubuzana okuthile nokuvela kwemiphumela emibi, ukwelashwa kungenzeka ukuthi kukhanseliwe futhi kube nokukhethwa i-analogue elula nephephile yeziguli.

Iningi labanesifo sikashukela abathatha iSiofor bahlala benelisekile ngemiphumela emihle. Lesi ngenye yezidakamizwa zesimanje ezisebenza kahle nezisebenza kahle, ezinekhono, uma zingasinqobisi isifo sikashukela, bese ziyidambisa kakhulu impilo yonke. Ukusetshenziswa kweSiofor kukuvumela ukuthi ubuye ngokushesha empilweni ephelele.