Imiyalo ephelele yokusetshenziswa kwesifo sikashukela nokubuyekezwa kwabanesifo sikashukela

Ekwelapheni i-mellitus yesifo sikashukela sohlobo 2, kunama-nuances amaningi ahlukene, futhi akwenzeki ngaso sonke isikhathi ukuthola umuthi osiza ukulawula i-glycemia eyi-100%. Ngenxa yezinhlobo zemithi ye-antidiabetic, ukudideka ekhanda akunqunyelwe kwabanesifo sikashukela.

Uma uzijwayele ngomuthi i-Diabeteson nemiyalo yawo esetshenziswayo, kepha nokho ungaqondi ngokuphelele ukuthi kufanelekile kuwe nokuthi kungashintshwa kanjani uma umuthi ungasizi, khona-ke le ndatshana iyasifanele leso sikhathi.

I-Diabeteson - umuthi wohlobo 2 sikashukela

Kumuntu onesifo sikashukela, enye yezindlela zokulwa nalesi sifo ngempumelelo yenza ngokwezifiso lokho okubizwa ngokuthi “ushukela wokuzila”. Kepha ekuphishekeleni ukufundwa okuhle kwe-glucometer, amaphutha amaningi angenziwa, ngoba inhloso yemithi kufanele ibe nesizathu, futhi lokhu kuyiqiniso ikakhulukazi kuDiabetes. Umuthi omusha waseFrance osungulwe umiselwe wonke umuntu - kusuka kubasubathi kuya kwabanesifo sikashukela, kodwa awusizo kuwo wonke umuntu.

Ukuqonda ukuthi ngubani okudinga ngempela, udinga ukuthola ukuthi hlobo luni lomuthi i-Diabeteson futhi ngesisekelo salokho okwakhiwayo okwenziwe. Umuthi uvela ku-sulfanilurea derivatives, usetshenziswe ngempumelelo emhlabeni wonke isikhathi eside.

Ebhokisini lekhadibhodi, njengasesithombeni, ungabona amaphilisi we-oval emhlophe anophawu olubhalwe ukuthi "60" kanye "DIA" ohlangothini ngalunye. Ngaphezu kwengxenye eyisebenzayo ye-gliclazide, iDiabetes nayo iqukethe izihlungi: i-maltodextrin, i-lactose monohydrate, i-magnesium stearate, i-silicon dioxide.

I-Diabeteson yigama lokuhweba lakwamanye amazwe, umkhiqizi osemthethweni wesidakamizwa yinkampani yaseFrance ekhemisi.

Igama elijwayelekile lamakhemikhali womkhiqizo yi-glyclazide, ngegama lesithako esisebenzayo.

Nge-gliclazide, kukhiqizwa izifanekiselo eziningi zemikhiqizo ehlukahlukene, ngakho-ke ekhemisi bangakhipha, ngokusho kweresiphi yokukhetha, hhayi i-French Diabeteson, kodwa enye i-analog esekwe kwi-gliclazide, ngentengo i-oda yesisindo eshibhile.

Isifo sikashukela

Impilo yeshelf umuthi iminyaka emi-2, ngokuzayo ayilungele ukwelashwa futhi kufanele ichithwe. Izimo ezikhethekile zesitoreji sayo azidingeki.

Esikhundleni se-Diabeteson yezidakamizwa, inani lentengo lisuka kuma-ruble angama-260-320, ikhemisi linganikeza ama-analogues:

• I-Diabefarm, RF;
• IGliclad, eSlovenia;
• UGlidiab weRussian Federation;
• UDiabinax, eNdiya;
• IGliclazide, RF;
• I-Predian, Yugoslavia;
• Diatika, India;
• IGlisid, eNdiya;
• Glucostabil, RF;
• IGlioral, Yugoslavia;
• I-Reklid, eNdiya.

Ngaphezu kwesidakamizwa esijwayelekile, uServier naye ukhiqiza iDiabeteson MV. Yonke eminye imishanguzo i-generics, abakhiqizi abayizungulanga, kodwa bamane bathola ilungelo lokukhipha, futhi lonke isisekelo sobufakazi sisebenza kuphela kumuthi wokuqala we-Diabeteson.

Ama-genetic abonakala ngekhwalithi yonjokozwayo, kwesinye isikhathi lokhu kuthinta kakhulu ukusebenza kahle kwezidakamizwa. Uhlobo lwesabelomali kunazo zonke lwe-analogue lunezimpande zaseNdiya nezesiShayina. Phakathi kwezinto eziyizinjini ezifuywayo ezihlula ngempumelelo imakethe yokufana kweDiabeteson, zihlonishwa nguGlibiab noGliclazid-Akos.

Ungasifaka kanjani esikhundleni sikashukela

Uma kungekho nketho efanelekile phakathi kwe-analogues efakwe kuhlu, ungakhetha:

1. Omunye umuthi ovela esigabeni samalungiselelo we-sulfonylurea njenge-glibenclamide, glycvidone, glimepiride;
2. Umuthi weqembu elihlukile, kepha ngenqubo efanayo yokwenza, njengokujwayelekile okusha okuvela esigabeni sobumba;
3. Ithuluzi elinomphumela ofanayo njengama-inhibitors we-DPP-4 - i-Januvia, Galvus, njll.

Kungaziphi izizathu ezingeke kudingekile ukukhetha okunye, kuphela uchwepheshe ongashintsha irejimeni yokwelashwa. Ukuzihlola kanye nokuzitholela ngokwakho isifo sikashukela kungalimaza kuphela!

Maninil noma Diabeteson - okungcono?

Izindlela ezahlukahlukene zokulawula isifo sikashukela sohlobo 2 zithinta ubungozi bezinkinga ezibulalayo ngezindlela ezihlukile. I-Glibenclamide - isakhi esisebenzayo seManinil sinamandla kakhulu kune-glyclazide - isithako esiyinhloko eDiabeteson. Ukuthi lokhu kuzoba wusizo kungatholakala yini kumazwana ochwepheshe abahlaziye imibuzo nge-Diabeteson kanye nokubuyekezwa kumaforamu.

Ungasifaka kanjani isicelo - imfundo

Umuthi olula ovela kuDiabeteson MV, owenziwe ngesisekelo se-hydrophilic matrix, wehlukanisa isilinganiso sokukhishwa kwengxenye esebenzayo. Ukuze uthole i-analogue ejwayelekile, isikhathi sokufakwa kwe-glycoside asidluli amahora ama-2 - 3.

Ngemuva kokusebenzisa i-Diabeteson MV, i-gliclazide ikhishwa ngangokunokwenzeka ngesikhathi sokudla, futhi sonke isikhathi, isilinganiso se-glycemic sigcinwa ngokukhipha ama-microdoses ukungena egazini phakathi nosuku.

I-analogue elula ikhiqizwa ngomthamo wama-80 mg, umphumela ongapheli - 30 no-60 mg. Ifomula ekhethekile ye-Diabeteson MV isize ukunciphisa isilinganiso somuthi, ngenxa yalokhu singasetshenziswa kuphela 1 isikhathi / usuku. Namuhla, odokotela akuvamile ukuthi bakhethe umuthi olula, kepha usatholakala kumakhemisi.

Odokotela batusa umuthi wesizukulwane esisha onamakhono okuhlala isikhathi eside, ngoba usebenza uthambile kakhulu kunezinye izidakamizwa ze-sulfonylurea, ingozi ye-hypoglycemia incane, futhi umphumela wethebhulethi eyodwa uhlala usuku.

Kulabo abakhohlwa ukuphuza amaphilisi ngesikhathi, umthamo owodwa inzuzo enkulu. Yebo, futhi i-endocrinologist ingakhuphula umthamo ngokuphepha, ifezekise ukulawula okugcwele kwe-glycemia esigulini. Ngokwemvelo, i-Diabeteson ichazwe ngokuhambisana nokudla okuphansi kwe-carb kanye nemithwalo yemisipha, ngaphandle kwayo noma iyiphi iphilisi ye-antidiabetesic ayisebenzi.

Indlela yokuvezwa kwesifo sikashukela

I-Diabeteson ingeyesigaba sezidakamizwa esivusa ama-pancreas futhi, ikakhulukazi, ama-b-cell abhekene nokukhiqizwa kwe-insulin. Izinga lomsebenzi lokukhuthaza okunjalo kulo muthi lilinganiswa, uma siqhathanisa iManinil noma iDiabeteson, khona-ke iManinil inethonya elinamandla kakhudlwana.

Ngohlobo 2 sikashukela, oluhambisana nanoma yikuphi ukukhuluphala, umuthi awukhonjisiwe. Kuyanezelwa kwirejimeni yokwelashwa, lapho zonke izimpawu zokuqothuka kwamandla okusebenza gland zibonakala futhi ukushukuma kuyadingeka ukuze kuthuthukiswe ukukhiqizwa kwe-insulin.

Umuthi uzobuyisa isigaba sokuqala sokukhiqizwa kwama-hormone uma onesifo sikashukela sehlile noma cha. Ngaphezu kwenhloso yayo eyinhloko (ukwehlisa i-glycemia), umuthi unomphumela omuhle emithanjeni yegazi kanye nohlelo lokujikeleza kwegazi. Ngokunciphisa ukuhlanganiswa kweplatelet (ukunamathela), kunciphisa amathuba okuqhekeka kwegazi emithanjeni emincane, kuqinisa i-endothelium yabo yangaphakathi, kudaleke ukuzivikela kwe-angioprotective.

I-algorithm yokuvezwa kwezidakamizwa ingamelwa ngokulandelana okulandelayo:

1. Ukugqugquzela ama-pancreas ukuthuthukisa ukugeleza kwe-hormone ukungena egazini;
2. Ukulingisa nokubuyiselwa kwesigaba sokuqala sokukhiqizwa kwe-insulin;
3. Ukunciphisa ukuhlanganiswa kweplatelet ukuvimbela ukuvela kwamaqhugwane emikhunjini emincane;
4. Umphumela omncane we-antioxidant.

Umthamo owodwa womuthi ugcina ukuhlangana okudingakalayo kwengxenye esebenzayo ku-plasma phakathi nosuku. Umuthi ufakwa emgqonyeni kwesibindi, izinso zawo ziyakhishwa (kufinyelela ku-1% - ngohlobo lwazo lwangempela). Ebusheni obukhulu, izinguquko ezibalulekile zezimpawu ze-pharmacokinetic azibhalwanga.

Izinzuzo nobubi bomuthi

Uma siqhathanisa iDiabeteson MV nezifanekiselo zesigaba se-sulfonylurea, khona-ke kungaphambi kwabo ekusebenzeni kahle:

• Ngokushesha i-indices ushukela;
• Isebenzisa isigaba sesibili sokukhiqizwa kwe-insulin, ibuyisa ngokushesha isiqu sayo ekuphenduleni ukubukeka kweglucose;
• Yehlisa amathuba okuqhekeka kwegazi;
• Ingozi yokuhlakulela i-hypoglycemia yehla yaya ku-7% (ama-analogues - avela ku-sulfanylurea - iphesenti liphakeme kakhulu);
• Uhlobo lokuphuza umuthi lungu-1 r / usuku. Ngakho-ke, kulula kwabashukela abakhohlwa ukulandela umuthi kadokotela;
• Isisindo siyazinza - I-Gliclazide kumathebulethi wokukhishwa aqinile ayifakeli inzuzo yesisindo;
• Kulula kudokotela ukuguqula umthamo - ubungozi be-hypoglycemia ephansi;
• Ama-molecule wezidakamizwa akhombisa izakhiwo ze-antioxidant;
• Amaphesenti aphansi wemiphumela emibi (aze afike ku-1%).

Kanye nezinzuzo ezingenakuphikwa, umuthi unezinkinga eziningi:

1. Umuthi lo unesandla ekufeni kwe-b-cell ebhekene nokukhiqizwa kwe-insulin;
2. Iminyaka emi-2-8 (kwabesifazane abanciphile - abasheshayo) isifo sikashukela esingu-2 siguqulwa sibe uhlobo 1 sikashukela;
3. Ukumelana ne-insulin, imbangela eyinhloko yesifo sikashukela sohlobo 2, umuthi awususi, kodwa futhi uyathuthukisa;
4. Ukunciphisa ushukela we-plasma akuqinisekisi ukuthi kuzoncipha ukushona kwesifo sikashukela - amaqiniso aqinisekisa izifundo zesikhungo somhlaba wonke esidumile i-ADVANCE.

Ukuze umzimba ungadingeki ukukhetha phakathi kwezinkinga ezivela kuma-pancreas noma kuma-pathologies wezinhliziyo, kufanele unake ukondleka okuphansi kwe-carb kanye nokuzivocavoca okwanele komzimba.

Izinkomba zokunquma umuthi

Isifo sikashukela senzelwe ukuguqula iphrofayili ye-glycemic, ukuvikela izinkinga zesifo sikashukela, ukunciphisa ingozi yokuhlaselwa yisifo senhliziyo, unhlangothi, i-nephropathy, i-retinopathy. Kepha kusetshenziswa nabasubathi ukwandisa izicubu zemisipha.

Ngakho-ke, kuyakhonjiswa:

• Abantu abanesifo sikashukela sohlobo lwesibili lwesifo sokulinganisa noma isilinganiso esinzima ngesisindo esijwayelekile futhi ngaphandle kwezimpawu zokumelana ne-insulin.
• Abasubathi ukuthuthukisa ukukhiqizwa kwe-insulin, okusheshisa ukukhula kwemisipha.

Isifo sikashukela asinqunyelwe iziguli njengohlobo lokuqala lokwelashwa. Kuyingozi nakwisifo sikashukela ngezimpawu zokukhuluphala, ngoba zinama-pancreas futhi ngakho-ke kusebenza ngomthwalo owandayo, kukhiqizwa izinkambiso ezingama-2-3 ze-insulin zokunciphisa ushukela. Ukuqokwa kukaDiabeteson kulo mkhakha wesifo sikashukela kungadala ukufa kwezimo zenhliziyo (CVS).

Kwenziwe ucwaningo olunzulu ngalolu daba, okusivumela ukuthi sinqume ubudlelwane phakathi kokukhethwa kwemithi kokukhethwa kokuqala kokwelashwa kwesifo sikashukela sohlobo 2 kanye namathuba okufa kwabantu. Okutholakele kuvezwe ngezansi.

1. Kumavolontiya anesifo sikashukela sohlobo lwe-2 othola i-sulfanilurea derivatives, eqhathaniswa neqembu elilawulayo elithatha i-metformin, ingozi yokushona kwe-CVS yayiphindwe kabili izikhathi, isifo senhliziyo (CHD) - izikhathi ezi-4.6, ingozi ye-cerebrovascular (NMC) ) - Izikhathi ezi-3.
2. Ingozi yokufa yesifo senhliziyo e-coronary, i-NMC yayiphezulu eqenjini ethola i-glycoslide, glycidone ne-glibenclamide kunasevolontiya abathatha i-metformin.
3. Kumavolontiya athola i-gliclazide, eqhathaniswa neqembu elithatha i-glibenclamide, umehluko wobungozi wawusobala: ukufa kwabantu kungaphansi kwama-20%, kusuka ku-CVS - ngo-40%, NMC - ngama-40%.

Ngakho-ke, ukukhetha kwe-sulfonylurea derivatives (kufaka phakathi i-Diabeteson) njengomuthi womugqa wokuqala kuvusa amathuba okufa okubili eminyakeni emi-5, amathuba okuthola ukushaya kwenhliziyo - ngezikhathi eziyi-4,6, isifo sohlangothi - amahlandla ama-3.Ngohlobo 2 lwesifo sikashukela esisanda kutholwa, akukho okunye okungenza iMetformin ibe isidakamizwa sokuqala. Ngokudla isikhathi eside (okungenani iminyaka emi-3) yesifo sikashukela, ubungozi bokuqalwa kwe-atherosclerosis buncishiswa kakhulu. Kwamanye amalungiselelo wesigaba se-sulfonylurea, lo mphumela awubonwa. Ngokunokwenzeka, umphumela we-antissteotic womuthi unikezwa ngamakhono ayo we-antioxidant avikela amaseli ku-oxidation.

Ngabe ukulimala kwesifo sikashukela 2 kungakulimaza muphi ividiyo?

Abasubathi bakashukela abanesifo sikashukela

Umuthi olwa nesifo sikashukela ukhulisa kakhulu ukuzwela kwesibindi, izicubu namafutha ku-insulin. Ekwakheni umzimba, isetshenziswa njenge-anabolic enamandla, engathengwa ngaphandle kwezinkinga ekhemisi noma kwi-Intanethi. Izazi zesifo sikashukela zisebenzisa i-Diabeteson ukubuyisela isigaba sokuqala sokukhiqizwa kwama-hormone futhi sithuthukise isigaba sesibili sokukhiqizwa kwaso.

Ithuluzi kufanele lisetshenziswe abakhi bomzimba abanama-b-cell aphilile. Umuthi uthinta i-metabolism yamafutha, ukugeleza kwegazi, ukuncipha kwegazi, unamandla we-antioxidant. I-Diabeteson iguqulwa ibe ngama-metabolites esibindini, umuthi ushiya umzimba ngokuphelele.

Kwezemidlalo, umuthi usetshenziselwa ukusekela i-anabolism ephezulu, ngenxa yalokho, umsubathi ukhulisa ngenkuthalo izicubu zemisipha.

Ngamandla wethonya lawo, angaqhathaniswa nama-insulin poplites. Ngale ndlela yokuthola isisindo, kufanele uhambisane kahle nemithamo, udle izikhathi eziyisithupha ngosuku (amaprotheni, ama-carbohydrate), ubheke impilo yakho ukuze ungaphuthelwa ukuqala kwezimpawu ze-hypoglycemia.

Qala isifundo ngamathebhulethi we-Ѕ, kancane kancane uphuze isilinganiso. Phuza iphilisi ekuseni ngokudla. Inkambo yokwamukelwa iyizinyanga eziyi-1-2, kuya ngenhlalonhle kanye nemiphumela. Ungakuphinda ngonyaka, uma usebenzisa i-Diabeteson kaningi kunesinye ezinyangeni eziyisithupha, izinkinga zempilo azinakugwenywa.

Ngezifundo zesibili, umthamo ungaphindwa kabili (kufika kumathebhulethi amabili / ngosuku). Awukwazi ukuthatha iDiabeteson ngemuva kokudla okulambile noma uthathe ezinye izindlela zokuthola isisindo. Umuthi uthatha amahora angama-10 futhi udinga umsoco ofanele ngalesi sikhathi. Esibonelweni sokuqala se-hypoglycemia, umsubathi udinga ukudla ibha noma amanye amaswidi.

Kwividiyo - ukusetshenziswa kweshukela ukuthola isisindo - izibuyekezo.

Contraindication ukusetshenziselwa

Yonke imishanguzo ine-contraindication, ngaphambi kokusebenzisa i-Diabeteson kubalulekile ukuba unake izexwayiso ezilandelayo:

• Uhlobo 1 sikashukela;
• Ukuzwela okuphezulu kuzakhi zefomula;
• I-Ketoacidosis, ikhefu likashukela;
• Izingane nobusha;
• Ukukhulelwa nokuncelisa ibele;
• Izifo ezibucayi zezinso nezinso;
• Ukungabekezelelani komuntu ngamunye kwezidakamizwa ezisuselwa ku-sulfonylurea;
• Ukusetshenziswa okufanayo kwe-miconazole (i-antifungal agent).

Ukusetshenziswa ndawonye kwezidakamizwa ezimbili kuwuthinta kanjani umphumela wokwelashwa? IMiconazole ithuthukisa amandla anciphisa ushukela weDiabetes. Uma ungalawuli iphrofayili yakho ye-glycemic ngendlela efike ngesikhathi, kukhona ingozi yokuthuthukisa i-hypoglycemia. Uma ingekho enye i-miconazole, udokotela kufanele anciphise umthamo we-Diabeteson.

Ngokuqapha, kufanele uphuze umuthi lapho uhlanganiswa ne:

1. I-Phenylbutazone (butadione);
2. Ezinye izidakamizwa ze-hypoglycemic;
3. Ama-Anticoagulants (warfarin);
4. Ngotshwala.

Isifo sikashukela siyakwazi ukukhulisa ukubekezelela utshwala. Lokhu kuboniswa ukufupheka komoya, ikhanda, i-tachycardia, ukugcwala kwamathumbu, kanye nokunye ukuphazamiseka kwe-dyspeptic. Uma uDiabeteson evusa i-hypoglycemia, khona-ke utshwala bufihla izimpawu zayo. Njengoba izimpawu zokudakwa ziyafana ne-glycemic, ngosizo olungakafaneli, ubungozi bokuwohloka kwesifo sikashukela luyakhula.

Umthamo ophucukile wotshwala onesifo sikashukela ingilazi yewayini elibomvu elomile lomcimbi. Futhi uma kukhona ukukhetha, kungcono ungabuphuzi nakancane utshwala.

Imiphumela emibi

Umcimbi omkhulu ophikisayo yi-hypoglycemia - ukwehla kwe-glucose ngaphansi kohla lokuqondiwe, kuhambisana nezimpawu ezilandelayo zomtholampilo:

• Ubuhlungu bekhanda nokuthinteka;
• Indlala engalawulwa;
• Ukuphazamiseka kwe-dyspeptic;
• Ukwehlukaniswa;
• Injabulo yokushintshana novalo;
• Ukuvinjwa, ukungakwazi ukugxila;
• Ukuphazamiseka kwengqondo nokukhubazeka okubukwayo;
• Ukuntuleka kokuzithiba, ukusizakala;
• Iyahluleka.

Ngaphezu kwe-hypoglycemia, kuneminye imiphumela emibi:

1. Imiphunga ye-allergic;
2. Ukwephulwa komgudu wokugaya ukudla;
3. Ukusebenza kahle ohlelweni lokujikeleza (i-anemia, ukuncipha kwamangqamuzana amhlophe egazi);
4. Ukukhula kwama-enzymes wesibindi AST ne-ALT.

Yonke imiphumela iyaphenduka futhi idlula ngaphandle kokungenelela kwezokwelashwa ngemuva kokukhanselwa kwesifo sikashukela. Uma umuthi unqunywe esikhundleni se-antidiabetesic agent ethile, khona-ke kungakapheli izinsuku eziyi-10 kuyadingeka ukulawula i-glycemia ukuze ugweme ukufakwa kwemiphumela eyingozi ku-hypoglycemia.

Lapho ukhetha i-Diabeteson, udokotela kufanele azise onesifo sikashukela ngemiphumela emibi engaba khona nezimpawu zokweqisa.

Ukuphathwa kwesifo sikashukela kanye nohlobo lwemithamo

Kwinethiwekhi ekhemisi, umuthi uvezwa ngezinhlobo ezimbili:

• Isifo sikashukela ngomthamo we-80 mg;
• I-Diabeteson MV enesisindo esingu-30 no-60 mg.

Kwi-Diabeteson ejwayelekile, indlela ejwayelekile yokuqalwa ingama-80 mg / ngosuku. Ngokuhamba kwesikhathi, yandiswa yaba izingcezu ezi-2-3 ngosuku, izisabalalisa ngemithamo eminingana. Ubukhulu ngosuku, ungathatha amaphilisi ama-4.

Kwi-Diabeteson eguquliwe, ingxenye yokuqala ingama-30 mg / usuku .. Uma kunesidingo, umthamo ulungiswa kahle. I-Diabeteson MV idliwa 1 r. / Day., Maximum - kuze kufike ku-120 mg. Noma ngabe kunikezwe umthamo omkhulu, kusazothathwa isikhathi ekuseni.

Njengazo zonke izidakamizwa zasekilabhini le-sulfanilurea, u-Diabeteson kufanele adakwe isigamu sehora ngaphambi kokudla. Ukuyiphuza ngesikhathi esiqondile esiboniswe yimiyalo, onesifo sikashukela sivumela umuthi ukuthi udakwe futhi ukhombise umsebenzi wawo ngesipuni sokuqala sokudla.

Ukusebenza komthamo okhethiwe kungahlolwa ekhaya, nge-glucometer.

Hlola ukusebenza kwayo ngaphambi nangemva kokudla (ngemuva kwamahora ama-2). Umthamo ofanele ubalwa ngawodwana: ngokusho kwephrofayili ye-glycemic kanye nokuhlolwa kwelebhu kwe-glycosylated hemoglobin HbA1C. Ungahlanganisa ukusetshenziswa kwe-Diabeteson nama-antidiabetic agents ngenye indlela yokusebenza.

Ukweqisa

Njengoba ukwelashwa noDiabeteson kuyingozi ekukhuleni kwe-hypoglycemia, umthamo owandiswa ngamabomu wezidakamizwa ukhulisa izimpawu zawo kaningana.

Lapho uzama ukuzibulala noma ukweqisa ngokweqile ngengozi, kufanele:

1. Ukuhanjiswa kwesisu;
2. Ukulawulwa kwe-Glycemia njalo ngemizuzu eyi-10;
3. Uma i-glucometer ingaphansi kokujwayelekile (5.5 mmol / L), phuzisa isiphuzo ngaphandle kokufaka izinongo;
4. Ukuqashwa kokusebenza komuthi - kuyo yonke inkathi yayo (amahora angama-24).

Ukwelashwa okuphelele kwesifo sikashukela sohlobo 2

Isifo sikashukela sivame ukusetshenziswa hhayi njengesidakamizwa esisodwa, kepha nasekwelapheni okuyinkimbinkimbi. Isebenzisana nawo wonke ama-antidiabetesic agents, ngaphandle kwezidakamizwa zesigaba se-sulfonylurea (zinendlela yokusebenza efanayo), kanye nesimo esisha: kubuye kusebenze ukucubungula kwehomoni, kepha ngendlela ehlukile.

UDiabeteson usebenza kahle ngokubambisana neMetformin. Ngokuqondene nalokhu, abakhiqizi baseRussia bakhulisa ngisho nomuthi ohlanganisiwe we-Glimecomb, ekwakhiweni kwawo okungama-40 g we-glycoslazide no-500 mg we-metformin.

Ukusetshenziswa komuthi onjalo kubonakaliswa ukwanda okuhle kokuthobela (onesifo sikashukela ubona irejimeni yemithi ebekiwe). I-Glimecomb ithathwa ekuseni nakusihlwa ngokushesha ngaphambi noma ngemuva kokudla. Imiphumela emibi yemithi ibuye yande nge-metformin ne-gliclazide.

Ukusebenzelana kwezidakamizwa

Kunezidakamizwa eziningi ezandisa ubungozi be-hypoglycemia uma zisetshenziswa kanyekanye noDiabetes. Udokotela kufanele aqaphele ikakhulukazi lapho ebeka i-acarbose, metformin, thiazolidinediones, DPP-4 inhibitors, ama-agonists e-GLP-1, kanye ne-insulin enoDiabetes.

Imithi eminingi ebekelwe iziguli ezinomfutho wegazi ophakeme ibuye ithuthukise namandla eDiabetes. Udokotela kumele akhumbule nge-β-blockers, ACE inhibitors neMAO, fluconazole, sulfonamides, i-histamine H2-receptor blockers, clarithromycin.

Uhlu oluphelele lwezidakamizwa ezikhulisa noma zenze buthaka umsebenzi wezithako eziyinhloko zefomula zingatholakala kwimiyalo yasekuqaleni. Ngisho nangaphambi kokuba anikeze isifo sikashukela, kubalulekile ukuthi umuntu onesifo sikashukela azise udokotela wakhe ngemithi, izithasiselo zokudla, itiye le-herbal aliphuzayo.

Yini abantu abanesifo sikashukela abacabanga ngayo ngesifo sikashukela

Ukubuyekezwa kwesifo sikashukela kuxutshwe mayelana neDiabeteson: kuyasiza ukulawula ushukela, kepha amaningi awakwazanga ukugwemeka. Amathebhulethi wokukhishwa kwe-Glyclazide-modified-release abekezelelwa kalula. Futhi imiphumela emibi ibonwa kaningi kwabanesifo sikashukela esivame ukuthatha isifo sikashukela iminyaka eminingana.

Uma uDiabeteson Engasizanga

Lapho uDiabeteson engayenzi imisebenzi yakhe, ngokusho kwama-endocrinologists, lokhu kungaba ngenxa yezizathu ezahlukahlukene:

1. Ukwehluleka ukulandela imigomo yokudla okune-carb ephansi, ukungasebenzi kahle komzimba;
2. Umthamo okhethwe ngendlela engafanele;
3. Ukwehla okunamandla kwesifo sikashukela, esidinga ushintsho ezindleleni zokwelapha;
4. Umlutha kumuthi;
5. Ukwehluleka ukulandela umuthi;
6. Umzimba awunandaba ne-gliclazide.

Kubalulekile ukukhumbula ukuthi isifo sikashukela sinqunyelwe umjikelezo olinganiselwe onesifo sikashukela. Ngakho-ke, ngaphambi kokuthatha umuthi, kubalulekile ukutadisha imiyalo kanye nalesi sihloko ukuze uqiniseke ukuthi ukuqokwa kunembile. Okuningi mayelana nezici

Isifo sikashukela sibuke ividiyo