Ungayisebenzisa kanjani isidakamizwa i-Augmentin SR?

I-Augmentin SR ingeyeqembu lama-penicillin angama-semisynthetic. Inomphumela we-bactericidal ngokumelana nokwehlukahlukana kwamagciwane amancane. Kuboniswa ekwelapheni kwezifo ezibangelwa amagciwane azwela enhlanganisweni yezinto ezisebenzayo ezingama-antibiotic.

I-ATX

Umuthi we-antibacterial wokusetshenziswa okuhleliwe. Ikhodi ye-ATX: J01CR02.

I-Augmentin SR inomphumela we-bactericidal ngokumelana nezinhlobonhlobo zamagciwane.

Khipha amafomu nokwakheka

Amatafula abunjwe nge-capsule embozwe ifilimu. Ithebhulethi eyi-1 iqukethe i-1000 mg ye-amoxicillin, i-62,5 mg ye-clavulanic acid kanye nabathola. Ku-1 blip strip pack lamathebulethi ayi-4. Ebhokisini 4, 7 noma 10 amabhulokhi.

Isenzo se-Pharmacological

Izakhi ezisebenzayo zesidakamizwa se-antibacterial semi-synthetic zisebenza ngokulwa nobubanzi bama-aerobes we-gram-positive ne-gram-negative ne-anaerobes.

Ama-beta lactamases aqeda umphumela we-bactericidal we-amooticillin. I-Clavulanic acid inethonya elincane le-antibacterial, kepha ivikela i-amooticillin ethonyeni lama-enzyme e-beta-lactamase, anamandla amakhulu okubhubhisa maqondana nalokho. Isiza ukubuyisa ukuzwela kwamagciwane ukuthi ibaluleke, inwebisa umsebenzi wayo we-bactericidal, ibangela ukumelana kwe-cephalosporins kanye nemithi elwa nama-penicillin.

I-Pharmacokinetics

Lapho zithathwa ngomlomo, izinto ezisebenzayo ze-Augmentin CP azonakaliswa endaweni ene-acid esiswini, zimunca ngokuphelele emgodini wesisu. Ukuqoqwa okukhulu kwezakhi ezisebenzayo ku-plasma yegazi kutholakala ngemuva kwemizuzu engama-90-120. Ukubopha kwezakhi amaprotheni kunobuthakathaka futhi kubalwa ne-18-23% yokuqoqwa kwazo kwe-plasma ephelele. Ukuqoqeka okukhulu kwezinto kuyabonakala esibindini. Ngaphezu kwesigamu umthamo othathwe ngomlomo udalulwa ngohlelo lwe-excretory olungaguquki.

Umuthi unqunyelwe i-bronchitis engapheli esigabeni esibuhlungu.

I-Augmentin SR isetshenziselwa ukwelapha i-pneumonia engapheli.

Umuthi ubekwa ngokuqapha lapho uguga.

Izinkomba zokusetshenziswa

Kubekelwe ukwelashwa kwezifo zamagciwane zephethini lokuphefumula - i-bronchitis engapheli esigabeni esibuhlungu, i-pneumonia engapheli, i-rhinosinusitis, evame ukubangelwa yizingqinamba ze-Streptococcus pneumoniae. Kusetshenziswa ekuzenzeni kwamazinyo ukuvikela ukutheleleka kwasendaweni ngemuva kokuhlinzwa.

Ingasetshenziselwa isifo sikashukela

Umuthi ubekwa njengengxenye yokwelashwa okuyinkimbinkimbi kwezifo zezakhi zofuzo ezithathelwanayo. Izakhi ze-antibiotic ezivela eqenjini le-penicillin azithinti ushukela wegazi, ngaphandle kwengozi yesimo se-hyperglycemic. Ngokuqapha kubekiwe ukubola kwesifo nasekugugeni. Umthamo kanye nesikhathi sokwelashwa kunqunywa ngawodwana.

Contraindication

Umuthi lo uphethwe ngemibandela ebangelwa yilezi zifo ezilandelayo:

• i-hepatitis noma i-cholestatic jaundice ngenxa yokusebenzisa ama-penicillin antibiotic;
• i-monocytic tonillitis;
• i-lymphocytic leukemia engapheli;
• isifuba somoya;
• ukutheleleka kwamathumbu emathunjini, kuhambisana ne-hemorrhagic colitis noma i-hemathemesis;
• hay fever.

Ayisetshenziswa uma kwenzeka kune-hypersensitivity kuya kuma-penicillin ama-antibiotic noma izingxenye zezidakamizwa.

Umuthi ubhekene ne-asthma ye-bronchial.

Umuthi awunqunyelwe umkhuhlane we-hay.

Umuthi awubekelwe i-leukemia engamahlalakhona.

I-Augmentin SR ichazwa ngokuqapha ezimweni zomsebenzi wesibindi kanye nezinso.

Ngesikhathi sokukhulelwa, umuthi awunconywa.

Ngesikhathi sokuncelisa, ukusetshenziswa kwe-antibiotic kungenzeka kuphela ngaphansi kokuhlolwa udokotela.

Ngokunakekela

Uma kwenzeka ukungasebenzi kahle kwesibindi nezinso, izifo zesisu zisetshenziswa ngaphansi kokuqondisa udokotela.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Akunconyelwe ukufaka isicelo, ngaphandle kokuthi, ngombono wochwepheshe, ukwelashwa okulapha amagciwane kuyadingeka. Lapho uthatha i-antibiotic ngesikhathi sokuncelisa, ubungozi bokuzwela luyakhuphuka, oluhambisana nokukhishwa kwama-metabolites obisini. Kulokhu, ukusetshenziswa kungenzeka kuphela ngaphansi kokuqondisa udokotela.

Ungayithatha kanjani i-Augmentin SR

Ukuze unciphise ingozi yokuphendula okungafuneki kusuka ohlelweni lokugaya ukudla, kuyadingeka ukuthatha umuthi ngesikhathi sokudla. Ukwelashwa kwezifo zokuphefumula zezifo zokuphefumula, kuthathwa umthamo wamathebulethi amabili ngosuku, uhlukaniswe ngemithamo emi-2. Isikhathi sokwelashwa ngama-antibiotic yizinsuku ezingama-7-9.

Ukuze uvimbele ukutheleleka kwasendaweni ngemuva kokungenelela kokuhlinzwa ohlinzeni lwamazinyo, ithebhulethi eyi-1 ichazwe izikhathi ezi-2 ngosuku. Isikhathi sokwelashwa esijwayelekile siyizinsuku ezingama-4-6.

Imiphumela emibi

Ngefundo elifushane, umuthi awuvamile ukudala ukusabela komzimba okungafuneki okuningi. Ingozi yemiphumela emibi iyanda uma izincomo zikadokotela noma ukwelashwa isikhathi eside kwe-anti-antibiotic kungalandelwa.

Ngokuphikisana nesizinda sokuphuza umuthi, ukuhlaselwa inhlokomo kanye nokuhlanza kungenzeka.

Ngemuva kokuthatha umuthi wokulwa namagciwane, kuvame ukuvela ikhanda, okuwuphawu lomthelela oseceleni.

Ukuthatha umuthi kungahambisana nesiyezi.

Ngemuva kokuthatha umuthi, ezinye iziguli zakha nephritis ye-tubulointerstitial.

Amapheshana wesisu

Kwezinye izimo, iziguli zikhononda nge-nausea, ukugabha, i-hemorrhagic colitis, ukuphazamiseka komzimba, i-candidiasis yolwelwesi lwama-mucous.

Kusuka ohlelweni lwe-hematopoietic kanye nohlelo lwe-lymphatic

Mhlawumbe ukwehla kwezinga lama-leukocytes, neutrophils, amaplatelet. Okuncane kakhulu ukubhujiswa kwe-pathological amaseli abomvu egazi, ushintsho enkombeni ye-prothrombin.

Isistimu yezinzwa ephakathi

Kwezinye izimo, kuba nobuhlungu bekhanda, ukwanda kokungezwani, isiyezi. Ezigulini ezithola imithamo ephezulu ye-antibiotic, kungenzeka ukuthi kube nokuzikhulula kwemisipha ngokuzithandela.

Kusuka ohlelweni lomchamo

Ezimweni ezingavamile kakhulu - i-pathology, ehambisana nokukhala kosawoti kumchamo, i-tubulointerstitial nephritis.

Kusuka emasosheni omzimba

Engxenyeni yesimiso sokuzivikela komzimba, ukungezwani komzimba kungenzeka - i-angioedema, i-anaphylaxis, i-vasculitis yesikhumba, i-erythema multiforme, umuthi we-toododerma, i-allergic bullous dermatitis.

Lapho usebenzisa umuthi, ungahlangabezana nokubonakaliswa okungekuhle njenge-vasculitis.

Ukusabela komzimba kulo muthi kubonakaliswa ukuqhuma esikhunjeni.

Ngemuva kokuthatha i-Augmentin SR, izifo zesibindi ezingavuvukalanga zingavela.

Engxenyeni yesibindi ne-biliary

Ezinye iziguli ezithola i-beta-lactam tiba elwa namagciwane zinokwanda okuthe xaxa kwamazinga e-ALT ne-AST. Izifo zesibindi ezivuthayo, i-cholestatic nonobstifying jaundice akuvamile ukwenzeka. Imvamisa, izinqubo ze-pathological zivuselelwa futhi ziyaqashelwa lapho kuthathwa amanye ama-cephalosporin kanye nama-antibiotic ochungechunge lwe-penicillin.

Engxenyeni yesikhumba nezicubu ezithambile

Ukusabela kwesikhumba kungenzeka - ukuqubuka kwesikhumba, umkhuhlane wezinzwa, ukuqubuka okufana nokuhlaselwa.

Imiyalo ekhethekile

Ngenkambo yokwelapha elwa namagciwane, kungenzeka ukuthuthukisa ukutheleleka kabusha ngesifo esisha esingelapheki ngenxa yokukhula kokunganaki ezingxenyeni ezisebenzayo ze-microflora. Kuyadingeka futhi ukulawula imisebenzi yezinso nesibindi, izitho zokwakheka kwegazi.

Ukuhambisana notshwala

Ukuphuza utshwala ngesikhathi sokwelapha nge-antibacterial akunconywa. Ukudakwa kwe-Ethanol kuhlangene nokuphuza umuthi kuholela ekusebenzeni kwe-hepatic kanye ne-renal.

Umthelela ekhonweni lokulawula izindlela

Ucwaningo lwethonya lekhono lokushayela izindlela nezimoto alwenziwe. Kodwa-ke, udinga ukukhumbula ngemiphumela emibi engaba khona, kufaka phakathi isiyezi, ukuqina kwemisipha etholakalayo.

Umuthi awuthinti amandla okushayela izimoto.

I-Augmentin SR ayinqunyelwe izingane ezingaphansi kweminyaka engu-16.

Ukuphuza utshwala ngesikhathi sokwelapha nge-antibacterial akunconywa.

Ukuyalela i-Augmentin CP ezinganeni

Ayibekelwe izingane ezingaphansi kweminyaka engu-16.

Sebenzisa ebudaleni

Asikho isidingo sokulungisa umthamo onconyiwe.

Sebenzisa umsebenzi wezinso ongasebenzi kahle

Iziguli ezinenkinga yokulimala kwezinso zidinga ukulungiswa komthamo owodwa kanye nokwanda kwesikhathi phakathi kwemithamo yomuthi.

Sebenzisa umsebenzi wesibindi okhubazekile

Ngesikhathi sokulashwa, iziguli ezinenkinga yesibindi somsebenzi zidinga ukulawula ukusebenza kwesitho. Ekwehlulekeni kwezinso, umthamo uguqulwa ngokuya ngezinga le-pathology.

Ukweqisa

Ayikho imininingwane ekutholakaleni kokubi kokubi okusongela impilo ngenxa yokusebenzisa ngokweqile kwe-Augmentin SR. Ezimweni eziningi, izinkomba zalesi simo isiyezi, ukuphazamiseka kokulala, ukwanda kokukhathazeka kwezinzwa. Kwezinye izimo, ukubanjwa okukholisayo kuyaphawulwa.

Uma kwenzeka kuba ne-overdose, ukwelashwa okubonakalayo kuyadingeka. Endabeni yokuphatha kwakamuva (ngaphansi kwamahora ama-3) wezidakamizwa, i-gastric lavage kanye ne-sorbents kubhekwe ukusiza ukunciphisa ukumuncwa kwe-amoxicillin. Into esebenzayo yesidakamizwa se-antibacterial isuswa egazini yi-hemodialysis.

Ukuthatha i-Mycophenolate Mofetil no-Augmentin kunciphisa ukuqina kwe-metabolite esebenzayo ye-mycophenolic acid.

Ukusetshenziswa kwe-Augmentin ne-Allopurinol kukhulisa ubungozi bokuthola ukusabela komzimba okungafuneki.

I-Augmentin CP inciphisa ukusebenza kwezindlela zokuvimbela inzalo ze-hormonal.

I-Amoxiclav inomphumela ofanayo emzimbeni.

UFlemoklav Solyutab angasebenza esikhundleni sezezimali.

Ungabuyisela umuthi umuthi onjengeMedoclav.

I-panclave isidakamizwa esifanayo.

Ukuxhumana nezinye izidakamizwa

Ukusetshenziswa kanyekanye kwesidakamizwa kanye nama-anticoagulants angaqondile kukhulisa isikhathi se-prothrombin. Ngokuqapha, inhlanganisela ye-Augmentin SR ne-Allopurinol ibekiwe mayelana nengozi eyandayo yokuthola ukusabela komzimba okungathandeki njengemisipha yesikhumba. Ezigulini ezithatha i-Mycophenolate Mofetil, lapho zihlanganiswa ne-Augmentin SR, kuyaphawuleka ukwehla okungu-2 ekuqoqweni kwe-metabolite esebenzayo ye-mycophenolic acid.

Ngokuphathwa kanyekanye kwama-bacteriostatic antibiotic noma ama-sulfonamides nomuthi olwa ne-antibacterial, ukwehla kokusebenza kokugcina kungenzeka. Ukuqina kokuqina komphumela we-antibacterial nokusetshenziswa kwe-Augmentin SR kanye nemithi elwa namagciwane eqembu le-ansamycin kuyaphawulwa. Umuthi ukhulisa ubuthi bezidakamizwa ze-cytostatic eqenjini lama-antimetabolites, wehlisa ukusebenza kwezindlela zokuvimbela inzalo zehormone. Ukusetshenziswa okuhlanganiswe ne-aminoglycosides kuholela ekusebenzisaneni kwemithi kwezidakamizwa.

Ama-Analog

Ama-analogues we-Augmentin SR ekwakhiweni yile mithi elandelayo ye-antibacterial:

• I-Amovicomb;
• I-Amoxivan;
• Amoxicillin + Clavulanic acid;
• Panklav;
• I-Amoxiclav;
• Arlet
• Flemoklav Solutab;
• I-Medoclav.

Ukukhethwa kwe-antibiotic efanayo esenzakalweni sayo se-pharmacological kuyavela ekuxilongeni, izici zomuntu kanye nobudala isiguli.

Uyini umehluko phakathi kwe-Augmentin SR ne-Augmentin

Ukulungiselela kuyahluka ngezindlela zokukhishwa nomthamo wezithako ezisebenzayo. Ifomu lokukhishwa kwe-Augmentin CP - Izibhebhe ezinokuguqulwa okuguquliwe nezenzo ezinde. Umthamo wezinto ezisebenzayo ngu-1000 mg + 62,5 mg. Inombolo yokuqala ihlala ikhombisa inani le-amooticillin kuthebhulethi eyi-1, elesibili - i-clavulanic acid.

I-Augmentin itholakala ngalezi zinhlobo ezilandelayo zomthamo:

1. Amacwecwe okuphatha ngomlomo. Kutholakala kwimithamo ye-250, 500 noma 875 mg + 125 mg. Bahluka kuphela kokuqukethwe kwe-amoxicillin.
2. Amandla wokumiswa. Kutholakala kwimithamo ye-125 mg + 31.25 mg nge-5 ml, 200 mg + 28,5 mg nge-5 ml no-400 mg + 57 mg nge-5 ml.
3. I-Powder yokulungiswa kwekhambi lomjovo. Kutholakala kwimithamo ye-500 mg + 100 mg ne-1000 mg + 200 mg.

Imibandela yekhefu lekhemisi

Ukuthenga lo muthi, ukuqokwa kukachwepheshe wezokwelapha kubalulekile.

Ngingakwazi ukuthenga ngaphandle kadokotela

Ikhishwa ngemithi kadokotela.

Intengo

Izindleko ezijwayelekile ngama-ruble ayi-720.

Izimo zokugcina i-Augmentin SR

Umuthi kufanele ugcinwe endaweni evikelwe umswakama nokukhanya emazingeni okushisa agcinekile we + 15 ° ... + 25 ° C. Ukuze ugweme ubuthi, udinga ukukhawula ukufinyelela kwezingane nomuthi.

Isikhathi sokuphelelwa yisikhathi

Izinyanga ezingama-24.

I-Augmentin itholakala ngesimo samathebulethi kwimithamo ye-250, 500 noma 875 mg + 125 mg.

I-Augmentin ikhiqizwa ngohlobo lwe-powder lokumiswa.

I-Augmentin ingathengwa kwifomu le-powder lapho kulungiswa khona isisombululo somjovo.

Ukubuyekezwa ku-Augmentin SR

Ngaphambi kokusebenzisa i-anti-spectrum antibiotic, kunconywa ukutadisha ukubuyekezwa kochwepheshe neziguli.

Odokotela

USuslov Timur (owelaphi), oneminyaka engama-37, uVladivostok.

Le antibiotic ivame ukubekelwa izifo zesipheshana sokuphefumula, ikakhulukazi i-sinusitis, tracheitis, laryngitis. Kusetshenziswe kahle kwizifo ezibangelwa ukutheleleka kwe-pneumococcal. Isicelo sesifundo sinikeza umkhuba omuhle. Ngemuva kokwelashwa, ukuphazamiseka kwesisu, i-candidiasis kungenzeka.

UChernyakov Sergey (otolaryngologist), oneminyaka engama-49 ubudala, uKrasnodar.

Inkampani ephumelelayo yezidakamizwa ze-antibacterial GlaxoSmithKline, isetshenziswa ekwelapheni izifo ezithinta izifo ezingelapheki futhi ezingalapheki. Ine-regimen dosage elula, ebekezelelwa kahle yiziguli. Akuvamile ukuthi kubangele ukusabela okuningi komzimba okungafuneki. Ngemuva kokudla umuthi, iziguli zivame ukukhononda ngezinkinga ngamathumbu (isifo sohudo).

Iziguli

UValeria, oneminyaka engama-28, uVladimir.

Udokotela wendawo waqoka le antibiotic lapho egula i-bronchitis. Umuthi wawusebenza kahle ekulweni nezimpawu zesifo, zonke izinsuku zizizwa zingcono. Ukubekezelela ama-antibiotic kuhle, ukusabela okuphikisayo okuningi, ngaphandle kokwephulwa kwe-microflora yamathumbu, akubonwanga. Kepha bekufanele ngithenga eminye imishanguzo yokuvuselela ukugaya.

U-Andrey, oneminyaka engama-34, u-Arkhangelsk.

Ngemuva kokuthola ukwelashwa isikhathi eside ngezinye izindlela, umkhuhlane ojwayelekile waphenduka i-bronchitis. Ngemuva kokuxhumana nodokotela, kwatholakala ukwelashwa okuyinkimbinkimbi nemithi eminingana, kufaka phakathi le antibiotic. Ngithathe i-1 ithebhulethi izinsuku eziyi-10. Ukuthuthuka kuzizwe ngemuva kosuku lwesithathu lwesicelo. Ekupheleni kwesifundo bephilile ngokuphelele. Manje, ngamakhaza, ngizama ukungabambezeli ukuvakasha kudokotela.