Isiraphu ye-Amoxicillin: isiyalo sokusebenzisa

Abaningi babheka ngephutha isiraphu ye-amoxicillin ekhemisi. Kepha isiraphu kuyindlela engekho yesidakamizwa. I-Amoxicillin iyatholakala ngohlobo lwama-granules ahloselwe ukulungiswa kokumiswa kokuphathwa komlomo.

Amafomu akhona akhishwe kanye nokwakheka

Lesi sidakamizwa sakhiqizwa ngesimo samathebulethi, amakhebuli noma ama-granules. Zonke izinhlobo zokukhishwa zenzelwe ukuphathwa komlomo, ngoba into esebenzayo ingena emzimbeni ngepheshana lesisu.

I-Amoxicillin iyatholakala ngohlobo lwama-granules ahloselwe ukulungiswa kokumiswa kokuphathwa komlomo.

Amakhebhulethi namathebulethi akhishwa ku-250 no-500 mg. Ifomu le-granular lenzelwe ukulungiselela ukumiswa kwezingane.

Into esebenzayo i-amoxicillin trihydrate ngezindlela ezahlukahlukene, ezincike kwifomu lokukhululwa.

Igama Lezwe elingafanele

Igama elingabambeki emazweni aphesheya yi-Amoxycillin (Amoxycillin).

I-ATX

Ikhodi ye-ATX: J01CA04.

Isenzo se-Pharmacological

I-Amoxicillin ine-bactericidal kanye ne-antibacterial effect. I-penicillin ye-aminobenzyl ekhiqiza umphumela we-bactericidal ngenxa yokuvinjwa kokuhlanganiswa kodonga lweseli lwamagciwane.

I-Pharmacokinetics

Ukuhluka kwe-bioavailability kwe-amoxicillin kuyahlukahluka ngokulingana nomthamo futhi kungaba ngama-75 - 90%. Ngokuphathwa komlomo kwe-500 mg, ukugxilwa kwayo ku-plasma kusuka ku-6 kuye ku-11 mg / L. Ngemuva kokuthatha i-Cmax, iplasma yakhiwa kungakapheli amahora ama-2.

I-15-25% ye-amoxicillin yakha isibopho ngamaprotheni e-plasma. Kubonakala ngokungena ngokushesha kwezicubu zamaphaphu, ukukhululeka kwe-bronchi, umchamo, i-bile nokugeleza kwendlebe okuphakathi. Uma ama-meninges engakhanyisiwe, khona-ke ukuqina kwento esebenzayo ku-cerebrospinal fluid kungafinyelela ku-20% wobukhulu bayo ku-plasma. Umuthi ungawela ku-placenta bese udlulela ubisi lwebele emithanjeni emincane.

Ukusuka ku-60 kuye ku-80% wento esebenzayo yesidakamizwa ikhishwa emzimbeni yizinso ngendlela efanayo efakwe kuyo.

Akukho ngaphezu kwe-25% yalesi umthamo obandakanyeka ku-metabolism, kwakheka i-penicilloic acid engasebenzi. Ukusuka ku-60 kuye ku-80% wento esebenzayo ikhishwa emzimbeni yizinso ngendlela efanayo lapho ingena. Le nqubo ihlala isilinganiso samahora ayisikhombisa .. Kutholakala umthamo omncane wento kuleyo bile.

Lokho okusiza i-amooticillin

Ezinganeni, umuthi ubekelwe lezi zifo:

1. Izifo eziphefumulayo.
2. I-pyelonephritis engapheli.
3. I-Purulent tonillitis (ezingamahlalakhona).
4. Izinhlobo ezahlukahlukene ze-bronchitis.
5. I-Pharyngitis, i-laryngitis.
6. I-Furunculosis.

I-Amoxicillin inqoba kahle isithiyo se-histoeticological, yakha ngokuphumelelayo ukugxilisa ingqondo kwezokwelapha.

Kusebenza kakhulu ezifweni ezithathelwanayo zalezi zinhlelo zomzimba:

• uhlelo lwezitho zofuzo;
• I-GIT (ngaphandle kwesisu esingezansi);
• ukutheleleka kwesikhumba (furunculosis, dermatitis);
• ipheshana lokuphefumula eliphezulu (i-pharyngitis, i-acute otitis media, i-angina, i-bronchitis, i-pulmonary abscess).

I-Amoxicillin isetshenziselwa ukwelapha i-pyelonephritis.

ILaryngitis iyinkomba yokuqokwa kwe-Amoxicillin.

I-Pharyngitis iyinkomba yokuqokwa kwe-Amoxicillin.

Umuthi usetshenziselwa ukwelapha i-furunculosis.

I-Amoxicillin imiselwe ukwelashwa kwe-angina.

I-Amoxicillin isetshenziselwa ukwelapha i-bronchitis.

I-Amoxicillin iphatha ngempumelelo i-otitis media yezindlebe eziphakathi nendawo.

Kunqunyelwe ekwelashweni kwazo zonke izinhlobo ze-gonorrhea, salmonellosis, isifo seLyme. Ngezifo ezinjalo, ukwelashwa ngokwakho akuvunyelwe. Umthamo odingekayo womuthi osohlobo lwe-trihydrate ungabekwa ngudokotela ngokuya ngemiphumela yokuhlolwa.

Ngenkambo enzima yesifo esithathelwanayo, i-Amoxicillin kufanele isetshenziswe kanye ne-clavulanic acid. Kulokhu, ukwamukela kungenziwa zombili ngesimo samathebulethi, nangendlela yemijovo.

Kunzima ukuphetha ngokusuka kulokho i-Amoxicillin esebenza kahle kakhulu. Konke kuya ngezimpawu zomzimba ngamunye, ubukhulu besifo kanye nomthamo ofanele.

Contraindication

Contraindication ifaka:

1. Hypersensitivity kulo muthi.
2. Umuzwa wokulwa nemithi elwa namagciwane we-penicillin necephalosporin uchungechunge (i-cross allergy).
3. I-mononucleosis ethelelekayo.
4. I-Lymphocytic leukemia.

Inani le-contraindication eziyisisekelo lingafaka futhi:

1. Iminyaka engaphansi kweminyaka emithathu.
2. I trimester yokukhulelwa.
3. Isikhathi sokuzala.
4. Ukwehluleka okukhulu kwezinso.
5. Ukwephulwa kohlelo lokugaya ukudla.
6. Isifo somoya (Broth).
7. I-colitis ehlobene ne-antibiotic (umlando).

I-Amoxicillin i-contraindication ku-asthma.

I-trimester yokukhulelwa kuwukuphikisana nokuphuza umuthi.

Ukwehluleka okukhulu kwe-renal kungukuphikisana nokuqokwa kwe-antibiotic.

Izingane ezingaphansi kweminyaka engu-3 ubudala azinqunyelwe i-Amoxicillin.

I-mononucleosis ethelelekayo kungukuphikisana nokusetshenziswa kwe-Amoxicillin.

Ngokutheleleka nge-herpes, ukusebenzisa i-Amoxicillin akugcini nje ngokungenamsebenzi, kodwa futhi kuyingozi.

Lapho uthatha i-amooticillin ne-clavulanic acid, ukungasebenzi kahle kwesibindi kwenzeka.

Ngokuphathwa okufanayo kwe-amoxicillin ne-clavulanic acid, ngokungeziwe ku-contraindication efakwe ohlwini, ukuphazamiseka kokusebenza kwesibindi kungavela.

Kufanele wazi ukuthi i-amooticillin, kanye namanye ama-antibiotic, asetshenziswa ekwelapheni lezo zifo kuphela ezibangelwa ukusebenza kwamagciwane. Ngokutheleleka ngegciwane (i-herpes, umkhuhlane, i-SARS), ayisebenzi kuphela, kodwa futhi iyingozi.

Ungayithatha kanjani i-amooticillin

Inkambo yokwelapha kanye nomthamo usethelwe ngokuhlukile.

Ukulungiselela u-100 ml wokumiswa, engeza amanzi ahlanzekile kumugqa welebuli (noma i-74 ml) ebhodleleni elinoqwembe futhi uzithintithe.

Abantu abadala nezingane ezingaphezu kweminyaka eyi-10 ubudala nesisindo esingaphezu kwamakhilogremu athathwa kuma-2 scoops (500 mg ngamunye) amahlandla ama-3 ngosuku. Ezimweni ezinzima zalesi sifo, umthamo wanda ufinyelela ku-1 g (4 scoops) amahlandla ama-3 ngosuku. Umthamo omkhulu wansuku zonke ngu-6 g.

Ngoshukela

Ukumiswa kune-sucrose ekwakhiweni kwayo, okumele kubhekelwe iziguli ezinesifo sikashukela.

Ezigulini ezinesifo sikashukela, ngesikhathi sokwelashwa kwezifo ezithathelwanayo ze-genitourinary ipheshana, i-Amoxicillin clavulanate 500/125 mg izikhathi ezi-3 ngosuku kuboniswa ngomlomo. Isikhathi sokwelashwa siyizinsuku ezi-5.

I-Amoxicillin ingathathwa ngaphandle kokudla.

Ngaphambi noma ngemuva kokudla

Ukudla akuphazamisi ukumuncwa Umuthi. Ngokuvumelana nalokhu, ingathathwa ngaphandle kokudla.

Zingaki izinsuku zokuphuza

Inkambo yokwelapha ithatha ezinsukwini ezi-5 kuya kwezi-2. Thatha umuthi okungenani izinsuku ezingama-2-3 ngemuva kokunyamalala kwezimpawu zesifo.

Imiphumela emibi ye-amoxicillin

Umuthi uvame ukubekezelelwa kahle. Kwezinye izimo, imiphumela emibi enjalo ingenzeka:

• i-conjunctivitis;
• umkhuhlane
• ushintsho ekwakhekeni kwegazi, i-anemia;
• i-candidiasis;
• colpitis;

Into esebenzayo ingaholela ekunciphiseni kokuhlanganiswa kwe-Vitamin K.

Ukusetshenziswa kwesidakamizwa kungaholela ekunciphiseni kwenkomba ye-prothrombin.

Amapheshana wesisu

Izinkinga ezifana nesicanucanu, i-dysbiosis, i-dyspepsia, isifo sohudo, i-stomatitis kungenzeka.

Isistimu yezinzwa ephakathi

Imiphumela emibi ohlelweni oluphambili lwezinzwa ingabonakaliswa yikhanda, ukuqwasha, ukungakhathali, ukukhathazeka, ukudideka.

Ngemuva kokuthatha umuthi, ezinye iziguli ziba ne- tachycardia.

Ngemuva kokuthatha i-Amoxicillin, kuvame ukuvela ikhanda, okuwuphawu lomthelela oseceleni.

Ngesikhathi sokwelashwa, ukuqwasha kungenzeka.

Ukusabela kokungezwani nomuthi kukhonjiswa i-urticaria.

Lapho usebenzisa umuthi, ungahlangabezana nokubonakaliswa okungekuhle njenge-conjunctivitis.

Ukungaphenduki kahle komzimba kulo muthi kungabonakala njengokucanuzelelwa kwenhliziyo.

Ngemuva kokusebenzisa umuthi, imiphumela emibi efana ne-rhinitis iyaphawulwa.

Kusuka ohlelweni lokuphefumula

Engxenyeni yohlelo lokuphefumula, kutholakala imiphumela emibi efana ne-rhinitis.

Kusuka ohlelweni lwezinhliziyo

Impendulo engemihle ngendlela ye-tachycardia ingahle ivele.

Allergies

Umuthi ungavusa izinhlobo ezahlukene zokwaliwa, okubandakanya i-hyperemia, i-edema, i-urticaria, i-dermatitis, ukushaqeka kwe-anaphylactic.

Imiyalo ekhethekile

Lapho uthatha umuthi, kufanele uhambisane nemiyalo nezincomo zikadokotela wakho. Lo mkhiqizo awuhloselwe ukusetshenziswa kwe-prophylactic. Uma ungalandeli imithetho yokwelashwa, amagciwane angakwazi ukuzivumelanisa nemiphumela yomuthi. Ukusetshenziswa kwayo okulandelayo kuzobe kungasebenzi.

Ungazinikeza kanjani izingane

Imvamisa, ukumiswa kubekelwe izingane ezingaphansi kweminyaka eyi-10.

Izingane ezingaphansi kweminyaka emi-2 ubudala ezinesisindo esingama-10 kg - ama-0.5 scoop amahlandla ama-3 ngosuku (noma ngesilinganiso sama-20 mg / kg ngosuku ngosuku ama-3 doses). Izingane ezisukela eminyakeni emi-2 kuya kwengama-5 ubudala ezinesisindo esisuka ku-10 kuye ku-20 kg - ngo-0,5 kuye ku-1 isipuni esilinganisiwe (125 kuya ku-250 mg / 5 ml) izikhathi ezintathu ngosuku. Eminyakeni engu-5 - 10 ubudala enesisindo somzimba esingama-20 kuye kwayi-40 kg, nezinkezo ezi-1 kuya kwezi-2 ezilinganisiwe (250 - 500 mg) kufanele zithathwe kathathu ngosuku. Umthamo ojwayelekile wosuku zonke wezingane kusuka eminyakeni emi-2 kuya kweli-10 ngu-20-40 mg / kg wesisindo somzimba ngosuku ngamalitha amathathu.

Ezinganeni nasezinganeni ezifika ezinyangeni ezi-3, umthamo wansuku zonke ophakeme kakhulu u-30 mg / kg wesisindo somzimba ngosuku kumthamo ama-2 njalo emahoreni ayi-12.

Ngesikhathi sokuqunjelwa, odokotela be-amoxicillin abancomi ukuthatha.

Uma kwenzeka kusetshenziswa izidakamizwa ngokweqile, kuqubuka uhudo olunzima.

Ukuqeda izimpawu ze-overdose, i-hemodialysis iyasetshenziswa.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Ngesikhathi sokukhulelwa, umuthi unqunywe ngokuqinile izinkomba, unikezwe ukulimala okungabangela i-fetus. Ucwaningo ngemiphumela emzimbeni wengane ngesikhathi sokukhula kwengane ayenziwanga, ngakho-ke, kufanele kuqashelwe lapho kudakwa lo muthi.

Ngesikhathi sokuqunjelwa, odokotela abaluleki ukuthi bathathe leli khambi, ngoba lingena emzimbeni wengane ngobisi lwebele futhi lingavusa ukungezwani komzimba kanye nokuqunjelwa.

Ukweqisa

Uma kwenzeka kuba ne-overdose, isifo sohudo esinzima singase sivele. Ukwelapha kuyimpawu. Kusetshenziswa kakhulu i-hemodialysis.

Ukuxhumana nezinye izidakamizwa

Kwenqatshelwe ukuhlanganisa i-metronidazole ne-amoxicillin ngesikhathi sokwelashwa ebuntwaneni. Umenzi walesi sidakamizwa ukhombisa ukuthi singasetshenziswa hhayi ngaphambi kweminyaka engu-3, ​​kepha kwezokuzivocavoca kwezingane zisebenzisa umuthi ukwelapha izingane ezisencane kakhulu.

Akuvunyelwe ukuthatha leli khambi kanyekanye nezinto ezinjalo namalungiselelo:

1. Ukuvimbela inzalo ngomlomo equkethe i-estrogen.
2. Ama-bactericidal antibiotic (cycloserine, rifampicin, vancomycin, njll).
3. Izidakamizwa ze-bacteriostatic (tetracyclines, lincosamides, macrolides, njll).
4. Ama-anticoagulants (ukusebenza kwe-anticoagulants engaqondile kuncishisiwe).
5. Ama-NSAIDs (acetylsalicylic acid, indomethacin, phenylbutazone, njll).
6. Aminoglycosides.
7. Kaolin.
8. I-Allopurinol nama-antacid.

I-Amoxicillin ayivunyelwe ukusetshenziswa ngokubambisana nezindlela zokuvimbela inzalo eziqukethe i-estrogen.

I-Amoxicillin kanyekanye ne-allopurinol ayivunyelwe.

Kwenqatshelwe ukusebenzisa lesi sidakamizwa ngokuhambisana nokuphuza utshwala, ngoba akuhambelani.

Ukuhambisana notshwala

Kwenqatshelwe ukusebenzisa lesi sidakamizwa ngokufana notshwala, ngoba asihambelani futhi sithinta kabi isibindi, okungaholela ekufeni. Ekupheleni kwenkambo yokwelashwa, kuyadingeka ukwenqaba ukuphuza utshwala izinsuku eziyisikhombisa kuya kweziyishumi.

Ama-Analog

Amagama alandelayo, aqukethe i-amo amoillillin esebenzayo, angabizwa nge-analogues ekhiqizwe amazwe ahlukahlukene:

1. Amoxillate.
2. I-Apo-Amoxy.
3. Amose.
4. I-Amoxisar.
5. I-Bactox.
6. I-Gonoform.
7. I-Grunamox.
8. UDanemox.
9. I-Ospamox.
10. Tysil.
11. Flemoxin solutab.
12. I-Hikontsil.
13. I-Ecobol.
14. I-E-mox.

Imibandela yekhefu lekhemisi

Ngokusebenzisa umuthi.

Ngingakwazi ukuthenga ngaphandle kadokotela

Ikhefu elingaphezulu kwe-counter livunyelwe

Izindleko

Intengo yamaphilisi okulungiswa kokumiswa kuyehluka kusuka kuma-ruble ayi-106 kuye kwangama-177.

Izimo zokugcina zomuthi

Gcina endaweni yokushisa engeqi ku-25 ° C lapho izingane zingafinyeleleki khona. Ukumiswa okuqediwe kugcinwa emazingeni okushisa +2 kuya + 8 ° C.

Isikhathi sokuphelelwa yisikhathi

Impilo yeshalofu yesidakamizwa yiminyaka emi-3. Ukumiswa okuqediwe kugcinwa isikhathi esingaphezu kwesonto eli-1. Ungasebenzisi ngemuva kokuphela kosuku.

Umkhiqizi

Umuthi ukhiqizwa emazweni ahlukahlukene, kubandakanya iRussia, i-USA, i-Israel, iJalimane, i-Austria, iCanada, neNdiya, neGibhithe, njl.

Izikhwanyana ezinendlela efanayo yokwenza izinto zifaka umuthi u-Amosin.

I-Ospamox inomphumela ofana ne-Amoxicillin emzimbeni.

I-Flemoxin solutab ibhekiswa kwizifinyezo zesakhiwo somuthi ofanayo entweni esebenzayo.

Ukwakheka okufanayo iHiconcil.

Uma kunesidingo, umuthi ungathathelwa indawo nge-Ecobol.

Ukubuyekezwa

UNatalia, oneminyaka engama-24, uKrasnodar

Wahlaselwa umkhuhlane kusukela ebuntwaneni. Ukuphindelela kwenzeka ngezikhathi ezi-1-2 ngonyaka. I-Amoxicillin isiza ukufika ezinyaweni zakho ngokushesha, akudingeki ukuthi uqambe amanga isonto.

UMaxim, oneminyaka engama-41 ubudala, u-Ufa

Angijwayele ukuguqukela emithini elwa namagciwane. Kepha uma ngivuma okuthile kumkhuhlane, lena yi-Amoxicillin. Inomphumela omnene, ayibizi. Ukusebenza kahle 100%.

UNelly, oneminyaka engama-38, uSaratov

Umuthi uyasebenza, kepha ungadala ukusabela okukhulu komzimba. Kwakukhona icala le-bacteriolysis, izinga lokushisa lenyuka, kwadingeka ngishayele udokotela. Isimo sibuyele kokujwayelekile.

U-Ana, oneminyaka engama-31, uSamara

Ikhambi lisize ukwelapha i-pyelonephritis. Ngiyayincoma.