I-Amoxicillin Umuthi olwa-synthetic okwenziwe ngeqembu le-penicillin. I-Drops Amoxicillin iyindlela yokukhulula engatholakali. Ngefomu loketshezi, lesi sidakamizwa asithengiswa. Amaconsi endlebe nawamehlo, ajwayelekile eRussia, kanye namaconsi ekhaleni, aqukethe ezinye izithako ezisebenzayo.
Amafomu akhona akhishwe kanye nokwakheka
Umuthi obizwa nge-Amoxicillin unezinhlobo ezi-3 zokukhishwa. Ngamunye wabo uqukethe into efanayo esebenzayo. Ezinye izinto ezisebenzayo ekwakhiweni kwalo muthi azifakiwe. Izinkampani ezenza imithi zinikela ngalezi zinhlobo ezilandelayo nemithamo:
- 250 noma 500 mg amaphilisi;
- amaphilisi we-250 noma 500 mg;
- granules yokulungiselela ukumiswa ku-5 ml yayo equkethe ama-250 mg we-amoxicillin.
I-Amoxicillin iyatholakala ngesimo sethebulethi.
Igama Lezwe elingafanele
I-Amoxicillin.
I-ATX
J01CA04.
Isenzo se-Pharmacological
Umuthi unomphumela we-bactericidal oqondiswe maqondana namagciwane a-gram-negative nama-gram-virus ahlukahlukene. Kodwa-ke, ayisebenzi ekwelashweni kwezifo ezibangelwa ama-microorganisms akwazi ukukhiqiza i-penicillinase noma abonise ukumelana kwe-ampicillin.
Cishe ikwazi ukuvikela ukukhula kokumelana kweHelicobacter pylori ku-metronidazole.
I-Pharmacokinetics
Ngokuphathwa ngomlomo kwalesi sidakamizwa, ukumuncwa emzimbeni wamathumbu kwenzeka ngokuphelele. Ukuqunjelwa okukhulu kwe-amoxicillin ku-plasma yegazi kutholakala ngemuva kwamahora we-1-2. Inani layo lilingana ngokuqondile nedosi futhi liyafana namanani atholwe ngokuphathwa kwe-intravenous and intramuscular yenani elifanayo lale nto esebenzayo. Indlela enkulu yokuqothula emzimbeni ngokusebenzisa izinso, isikhathi sokuphila esisusa amahora angama-1-1,5.
Yini esiza i-amooticillin?
Kunconywa i-Amoxicillin ekwelapheni izifo ezinjenge:
- i-tonsillitis, inyumoniya, i-bronchitis nezinye izilonda zezitho ze-ENT kanye nepheshana lokuphefumula;
- izinqubo zokuvuvukala zamapheshana okuchama, kufaka phakathi i-urethritis, pyelonephritis;
- izifo ezithathelwanayo nezokuvuvukala zesikhumba nezicubu ezithambile;
- ukutheleleka kohlelo lokuzala kanye nepheshana lesisu.
Ngezifo ezingenhla, isidakamizwa singasetshenziswa sobabili sihlanganiswe ne-clavulanic acid, futhi njengesixazululo esizimele. Kwezifo zesisu ezihambisana ne-Helicobacter pylori, i-amooticillin ichazwa kuphela ngokuhlanganiswa ne-metronidazole.
Ngoshukela
I-Amoxicillin ayikushintshi ukugcwala kwe-glucose kwiplasma yegazi, ngakho-ke kuvunywa ukusetshenziselwa isifo sikashukela mellitus. Kunqunyelwe ikakhulu ezifweni ezifana:
- i-furunculosis;
- i-fasciitis;
- unyawo lwesifo sikashukela.
Contraindication
Umuthi uphulwe ngalezi zimo ezilandelayo:
- i-hypersensitivity to vitu ezivela eqenjini lama-penicillin nama-cephalosporins;
- i-mononucleosis esithathelwanayo;
- ukutheleleka kwamathumbu emathunjini, kuhambisana nezimpawu ezinjengokurhudula nokugabha;
- izifo ezibangelwa amagciwane;
- isifuba somoya;
- i-lymphocytic leukemia;
- hay fever;
- i-allergic diathesis.
Ungayithatha kanjani i-amooticillin?
Umthamo owodwa we-Amoxicillin unqunywa ngudokotela ngokuya ngokuqina kwalesi sifo, kucatshangelwa ubudala nesisindo sesiguli. Ngokuya ngezincomo zomkhiqizi ezinikezwe emiyalweni yokusetshenziswa, ibanga lomthamo ngokuya ngeminyaka yile:
- kuze kube yiminyaka emi-2 - ama-4.5 mg ngekhilogremu ngayinye yesisindo;
- Iminyaka engu-2-5 - 125 mg;
- Iminyaka engama-5- 10 - 250 mg;
- kwiziguli ezindala nezingane ezingaphezulu kweminyaka engu-10 ubudala nezinesisindo esingaphezu kwamakhilogremu angama-40, kuye kwabikwa izifo ezingama-250-500 mg, ezinezifo ezinobunzima obukhulu kuze kufike ku-1 g.
Thatha umuthi ku-dosage ekhonjisiwe kathathu ngosuku njalo emahoreni ayi-8.
Ngaphambi noma ngemuva kokudla?
Ukudla akulimazi i-bioavailability lomuthi. Ngakho-ke, kumuntu onesistimu yokugaya enempilo, akunandaba ngaphambi noma ngemuva kokudla ukuze aphuze amaphilisi namaphilisi. Kepha ukwenza lokhu ngemuva kokudla kungcono kakhulu ezigulini ezihlushwa yizifo ezinjengokuthi:
- i-gastritis noma izilonda zesisu noma amathumbu;
- i-bowel syndrome;
- i-colitis noma i-enteritis;
- dysbiosis;
- ukuphazamiseka kwesitulo.
Ngaphezu kwalokho, ukuthatha umuthi ngemuva kokudla kunconywa ezinganeni ezingaphansi kweminyaka eyi-10.
Zingaki izinsuku zokuphuza?
Isikhathi sokwelashwa sincike kulesi sifo futhi sinqunywa ngudokotela esigulini ngasinye ngawodwana. Umenzi utusa ukuthatha lo muthi ngezinsuku ezingama-5 kuya kwezingu-12, kuye ngokuthi ubukhulu besimo kanye nokuba khona kwezinkinga.
Imiphumela emibi ye-Amoxicillin
Amapheshana wesisu
Lapho uthatha lo muthi olwa namagciwane, kungavela lezi zimo ezilandelayo:
- isicanucanu nokuhlanza
- ukuphazamiseka kwesitulo;
- ukwephulwa kokubona ukunambitheka;
- umsebenzi owengeziwe wama-enzyme wesibindi;
- Ubuhlungu esifundeni se-epigastric.
Isistimu yezinzwa ephakathi
Lapho uthatha i-Amoxicillin kusuka ohlelweni lwezinzwa, kungaba nokuvela okungathandeki okulandelayo:
- Isiyezi
- ukudideka kokwazi;
- iminyakazo
- i-peripheral neuropathies;
- isimo sokudangala.
Kusuka ohlelweni lokuphefumula
Izitho eziphefumulayo zingaphendula nge-Amoxicillin ngama-bronchial spasms noma ngokuvela kwe-dyspnea.
Kusuka ohlelweni lwezinhliziyo
Ukuthatha lo muthi olwa namagciwane kungakucasukela:
- ukuncipha kwengcindezi yegazi;
- ukuzindla kwenhliziyo;
- Ukunwetshwa kokuphumula kwe-QT;
- ukuthuthukiswa kwe-phlebitis.
Allergies
Ukusabela kwe-allergenic ku-amooticillin kungenzeka ngesimo salezi zimo ezilandelayo:
- i-urticaria;
- i-rhinitis;
- i-conjunctivitis;
- izinhlungu ezihlangene ezihambisana nomkhuhlane;
- ukwethuka kwe-anaphylactic.
Imiyalo ekhethekile
Lapho unquma i-Amoxicillin, kufanele kukhunjulwe ukuthi ngokusebenza kokulimala kwezinso, impilo yengxenye yalesi sidakamizwa evela emzimbeni iyanda. Ngakho-ke, umthamo kanye nezikhawu phakathi kwemithamo kufanele ushintshwe.
Ngaphezu kwalokho, i-Half-life ingahlala isikhathi eside ezinganeni ezisanda kuzalwa neziguli esezikhulile.
Ungayinikeza kanjani izingane?
Umuthi uvunyelwe ukwelashwa kwezingane ezifweni ezibangelwa ama-microorganisms azwelayo kuwo. Iziguli ezingaphansi kweminyaka engu-5 ubudala zinconywa ukuthi zisebenzise lo muthi ngendlela yokumiswa. Umthamo unqunywa udokotela oya khona.
Ukuhlanganiswa kwe-amoxicillin nge-metronidazole kufanele kugwenywe kubantwana.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Le antibiotic yeqa umgoqo we-placental futhi itholakala ubisi lwebele. Inhloso yayo ngesikhathi sokukhulelwa nangemva kokuzalwa kwengane kuze kube sekupheleni kokukhipha isisu kufanele yenziwe kuphela ezimweni lapho inzuzo kumama yokwelashwa okunjalo idlula ingozi engaba khona enganeni.
Ukweqisa
Izimpawu zokweqisa ngokweqile kuzoba ukuphazamiseka emgodini wokugaya ukudla, njengokucanuzelelwa kwenhliziyo, ukugabha nohudo. Lesi simo singahambisana nobuthakathaka nekhanda. Ukwelashwa okubonakalayo kukhonjisiwe. Ukusheshisa i-excretion yento esebenzayo evela emzimbeni, i-hemodialysis ingasetshenziswa.
Ukweqisa kwalo muthi kungaholela kulokhu:
- ukwephula ukwakheka kwegazi;
- umsebenzi wezinso ongonakalisiwe;
- i-jaundice nokuthuthukiswa kokuhluleka kwesibindi.
Ukuxhumana nezinye izidakamizwa
I-Amoxicillin inciphisa umphumela wokuvimbela inzalo ngomlomo nezidakamizwa ezenziwe nge-para-aminobenzoic acid, ulwa namagciwane alwa namagciwane. Igqamisa isenzo sama-anticoagulants, okuholela ekwandeni kwesikhathi se-prothrombin.
Ukuphatha ngokuhlanganyela ngama-diuretics, ama-NSAIDs, i-probenecid, i-phenylbutazone kubambezela inqubo yokukhuphuka kwe-amoxicillin emzimbeni.
Inhlanganisela ne-ascorbic acid isebenzisa ukufakwa komuthi. I-Glucosamine, ama-laxatives, kanye nezinto ezivela eqenjini lama-antacid nama-aminoglycosides akhubaza ukumuncwa kwe-amoxicillin.
Ukuhambisana notshwala
I-Amoxicillin ayihambisani notshwala, ngoba inhlanganisela enjalo ayikwazi kuphela ukunciphisa ukusebenza kahle kokwelashwa, kodwa futhi iholele ekudakweni.
Ama-Analog
Ama-analogues we-Amoxicillin afaka izidakamizwa ngento efanayo esebenzayo. Phakathi kwazo kukhona:
- I-Ecobol;
- I-Ospamox
- Flemoxin Solutab.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela?
I-Amoxicillin iyisidakamizwa esinqunyelwe, kepha amakhithi aseRussia ahlangana kakhulu namakhasimende futhi awadingi isiqinisekiso senhloso yalo muthi.
Intengo
Enye yamakhemisi aseRussia kwiwebhusayithi yayo inikezela ukuthenga lo muthi ngamanani alandelayo:
- Iphakethe lamakhompiyutha ayi-16, akhishwe ukukhathazeka kweHemofarm, kumthamo wama-250 mg ubiza ama-ruble angama-52.8, ama-ruble ayi-500 - 95,7.;
- Imikhiqizo yeBarnaul Medical Products Plant izobiza ama-ruble angama-67,5. kwamaphilisi angama-16 aqukethe ama-500 mg we-amooticillin;
- Iphakethe eliqukethe amaphilisi angama-20 omkhiqizo waseRussia libiza ama-ruble angama-32.3. kuma-ruble angama-250 nama-ruble angama-48.6. kwe-500 mg;
- Ibhodlela lama-granules ukulungiselela ukumiswa - ama-ruble angama-96.4.
Izimo zokugcina zomuthi
Amatafula, amakhebuli kanye nemifula kungagcinwa emazingeni okushisa amakamelo, into esemqoka ukuthi uwavikele elangeni futhi anqande ukufinyelela kwezingane endaweni yokugcina izinto. Ukumiswa okuqediwe kugcinwa esiqandisini.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelufu yokumiswa okulungiselelwe ingamaviki ama-2. Ngezinye izindlela, umuthi ungagcinwa iminyaka emi-4.
Umkhiqizi
E-Russia, i-Amoxicillin ikhiqizwa yizinkampani zemithi ezilandelayo:
- I-North Star
- I-Dalchimpharm;
- Isitshalo semikhiqizo yezokwelapha iBarnaul;
- Isazi sebhayoloji;
- Izinto eziphilayo
Ngaphezu kwalokho, lo muthi ukhiqizwa yizinkampani zase-Europe:
- IHemofarm, eSerbia;
- ESandoz, e-Austria;
- Umkhiqizo waseNatur, eHolland.
Ukubuyekezwa
U-Eugene, oneminyaka engama-42, uSyzran: "Ngokusebenza kwakhe isikhathi eside njengodokotela ojwayelekile, wayeqiniseka ukuthi i-amooticillin iyi-antibiotic ethembekile. Ngincoma ezigulini zami ukuthi zithenge imikhiqizo ezinkampanini zaseYurophu, ngoba, ukuthembela kuzibuyekezo eziningi zeziguli, ngafinyelela esiphethweni sokuthi kulula ukubekezelela futhi mancane amathuba okuba kubange imiphumela emibi. Ngaphezu kwesidakamizwa esisodwa ngisebenzisa inhlanganisela ne-clavulanic acid, ngibheka lokhu kusebenza okusebenzayo kakhulu.
URenata, oneminyaka engama-32, uKazan: "Udokotela unikeze inkambo ye-Amoxicillin ukwelapha i-bronchitis. Umuthi wasiza ngokushesha, akukho ukusabela okungekuhle. Ngijabule ngomsebenzi wesidakamizwa."
