IGlucophage noma i-Glucophage Long ngama-biguanides. Babekiwe lapho kunesidingo sokuzinzisa izinqubo ze-metabolic, ukuthuthukisa ukuzwela kwamangqamuzana ukungena ku-insulin.
Umphumela wokwelapha wezidakamizwa ezethulwe kuyefana, ngakho-ke udokotela uzokwazi ukubona ukuthi yimuphi umuthi ongcono, ngokuya ngesimo, egxile emiphumeleni yokuhlolwa nokuhlolwa.
Isici se-Glucophage
Umuthi ubekelwe ukwelashwa kwesifo sikashukela sohlobo 2. Kubhekiselwa kuzidakamizwa ze-hypoglycemic. Isithako esikhulu esisebenzayo yi-metformin. Uhlobo lomuthi lucwecwe oluyindilinga olumhlophe noma olwe-oval.
IGlucophage ichazwa ekwelapheni isifo sikashukela sohlobo 2.
Umphumela wehlisela ushukela utholakala ngenxa yokulandelayo:
- ukwakheka kwe-glucose kuma-hepatocytes kuyancipha;
- imetabolism iyathuthuka;
- amazinga we-cholesterol yegazi ayancipha;
- ukuzwela kweseli kokunyuka kwe-insulin, ngakho-ke i-glucose imunca kahle.
I-bioavailability yesidakamizwa ingama-60%. Umuthi uqhutshwa yisibindi futhi ukhishwe emchameni ngokusebenzisa izingubu zezinso ne-urethra.
Ngabe iGlucophage yinde kanjani
Kungokweqembu elifanayo nesidakamizwa esedlule, okungukuthi, kuhloselwe ukwehlisa inani loshukela egazini. Inhlanganisela esebenzayo ekwakhiweni iyafana - i-metformin. Amathebulethi asesimweni samaphilisi, aboniswa isenzo esenziwa isikhathi eside.
Umuthi awubangeli ukuhlanganiswa kwe-insulin futhi awukwazi ukuvusa i-hypoglycemia. Kepha kwizakhiwo zamaselula, ukuzwela kwe-insulin kuyanda. Ngaphezu kwalokho, isibindi sakha ushukela omncane.
Lapho amaphilisi ephuzwa ngomlomo, into esebenzayo igxilwa kancane kunokuba ngomuthi unesenzo esisejwayelekile. Isilinganiso esiphezulu sokuthathwa kwesithako esisebenzayo senzeka ngemuva kwamahora angama-7, kepha uma kuthathwe ama-1500 mg wekhompiyutha, isikhathi sinwetshwa sibe yingxenye yosuku.
Zombili lezi zidakamizwa zibekelwe ukwelashwa kwesifo sikashukela sohlobo 2.
Ukuqhathaniswa kweGlucophage Glucophage Long
Yize izidakamizwa zibizwa ngethuluzi elifanayo, akuyona into efanayo - azinakho nje ukufana, kodwa futhi nomehluko.
Ukufana
Lezi zinkampani ezimbili zaseFrance zikhiqiza imikhiqizo yomibili. Amaphilisi ayatholakala. Kwiphakethe elilodwa lezingcezu eziyi-10, 15 nezingama-20. Kumakhemisi, ungathenga umuthi kuphela ngokukunikezwa. Ngenxa yengxenye efanayo esebenzayo, izakhiwo zezidakamizwa ziyafana.
Ngenxa yokusetshenziswa kwezidakamizwa ezinjalo, izimpawu zesimo se-hyperglycemic ngokushesha zinyamalale. Izidakamizwa zithinta umzimba womuntu kalula, zisiza ukulawula inkambo yesifo, zilawula inani likashukela egazini.
Kepha le mithi inezinye futhi izakhiwo ezizuzisayo. Zithinta kahle wonke umzimba, zivimbele i-pathologies yesifo senhliziyo, izinso.
Izinkomba zokusetshenziswa zombili lezi zidakamizwa ziyefana. Zisetshenziselwa isifo sikashukela sohlobo lokuncika kwe-insulin, lapho ukudla kungasasizi, kanye nenkinga yokukhuluphala. Ezinganeni, umuthi unqunywa kuphela ngemuva kokufika eminyakeni eyi-10. Kuvinjelwe ingane encane nezinsana ezisanda kuzalwa.
Ukuxhumanisa ukusetshenziswa kwemithi nakho kuyefana. Lokhu kufaka lokhu okulandelayo:
- ukukhulelwa nokuqunjelwa;
- coma
- ketofacidosis ebangelwa isifo sikashukela;
- umsebenzi wezinso ongonakalisiwe, ukwehluleka kwezinso;
- ukwehluleka kwesibindi;
- i-lactic acidosis;
- ukwanda kwezifo ezithathelwanayo;
- ukusinda kokulimala nokuhlinzwa;
- utshwala;
- ukungabekezeleli umuthi noma izakhi zawo ngazinye.
Izindlela zingadala imiphumela emibi enjalo:
- ukuthuthukiswa kwe-lactic acidosis;
- ubungozi be-hypoxia;
- ukuphazamiseka ekukhuleni kwesibeletho ngesikhathi sokukhulelwa.
Imiphumela emibi ye-Glucophage ne-Glucophage Long nayo ijwayelekile. Lokhu kusebenza kokulandelayo:
- ukukhanuka kwenhliziyo kanye nokuhlanza, isifiso sokudla esingesihle, ukwanda kwegesi, ukuhudozela, ulwelwe olungemnandi lwensimbi emlonyeni;
- i-lactic acidosis;
- i-malabsorption yamathumbu ka-vithamini B12;
- i-anemia
- ukuqhuma kwesikhumba, ukulunywa, ukukhonkotha, ubomvu nezinye izindlela zokubonisa.
Uma ungalandeli umthamo, khona-ke izimpawu ezinjengokuhlanza, umkhuhlane, isifo sohudo, ubuhlungu besisu, ukukhuphuka kwenhliziyo, ukuqaqeka kokunyakaza kokuhamba kungavela. Uma kwenzeka kweqisa ngokweqile, kuyadingeka ukuthi uyeke ukusebenzisa lo muthi bese uya esibhedlela ngokushesha, lapho kunqunywe khona ukuhlanza i-hemodialysis komzimba. Ngakho-ke, iziguli zivame ukubhekwa.
Uyini umehluko
Ngaphandle kokuthi iGlucofage ne-Glucophage Long zinesithako esiyisisekelo esisebenzayo, izingoma zazo azifani. Lokhu kusebenza kumakhompiyutha asizayo. I-Glucophage ngaphezu kwalokho iqukethe i-hypromellose, i-magnesium stearate, kanye nenguqulo yamaphilisi - i-hypromellose, carmellose.
Ngaphandle, amaphilisi nawo anokuhluka. E-Glyukofazh bayindilinga, futhi kwa-Glyukofazh Long banefomu lamaphilisi.
Futhi, izidakamizwa zinhlobo oluhlukile lohlelo. IGlucophage kufanele ithathwe kuqala ku-500-1000 mg. Ngemuva kwamasonto ambalwa, umthamo weGlucofage ungakhuphuka ngokuya ngezinga likashukela egazini kanye nesimo esivamile sesiguli. I-1500-2000 mg ivunyelwe ngosuku, kepha hhayi ngaphezulu kwe-3000 mg. Kungcono ukuhlukanisa le mali ibe ngama-reception amaningana: thatha ebusuku, kwasemini kanye nasekuseni. Lokhu kusiza ukunciphisa amathuba okuvela okubi okuvela kuphephabhuku lesisu. Kusho ukuphuza ngokushesha ngemuva kokudla.
Ngokuqondene ne-Glucophage Long, udokotela ukhetha umthamo wesiguli, egxile eminyakeni yakhe, izici zomzimba nesimo sempilo. Ngasikhathi sinye, imali ithathwa kanye kuphela ngosuku.
Yikuphi okushibhile
Ungathenga iGlucophage eRussia emakhemisi ngenani lama-ruble ayi-100, kuthi ngamathebulethi wesibili, izindleko ziqala kusuka kuma-ruble angama-270.
Yini engcono iGlucofage noma i-Glucofage Long
Womabili la makhambi anomthelela omuhle emzimbeni wonke. Basiza ukulwa nokukhuluphala, bathuthukise ukusebenza kohlelo lwezinhliziyo, bathinte umetabolism, futhi banciphise amazinga kashukela egazini.
Kepha udokotela oholayo kuphela onganquma ukuthi yisiphi isidakamizwa esifanelekile esigulini esithile. Njengoba zombili izidakamizwa zinento efanayo esebenzayo, izinkomba, ama-contraindication, imiphumela emibi, umphumela we-pharmacological.
Ngoshukela
Le mishanguzo ingeyoqembu le-Biguanides, okungukuthi, yakhelwe ukunciphisa ukugcwala koshukela egazini. Kodwa-ke, azithinti ukukhiqizwa kwe-insulin, kepha zenza izinhlaka zamaselula zizwakale kakhulu kule hormone.
Zombili lezi zidakamizwa zinomphumela ofanayo. Umehluko kuphela osesimweni somphumela.
Ukwehla kwesisindo
I-Glucophage kanye nenguqulo yayo ende yenziwa njengendlela yokwelapha isifo sikashukela. Kodwa umphumela wokunciphisa umzimba ungatholakala, njengoba isifiso sokudla somuntu sincipha.
Ngaphezu kwalokho, into esebenzayo yesidakamizwa ivimbela ukumuncwa okuphelele kwama-carbohydrate emathunjini.
I-Glucophage ne-Glucophage Long ingasetshenziselwa ukunciphisa umzimba.
Ukubuyekezwa kweziguli
U-Ana, oneminyaka engama-38, u-Astrakhan: "Ngemuva kokuzalwa, kwaba nokungasebenzi kahle kwe-hormonal. Walulama - waba nesisindo esingamakhilogremu angama-90. Udokotela wathi kwakuyisifo se-metabolic. Unikezwe isidlo sokudla kanye ne-Glucophage. Ngaphezu kwalokho, wanquma ukufunda ukubuyekezwa kwalabo abathathe lo muthi. Ngemuva kwezinyanga ezimbili, kwenzeka ukuthi alahlekelwe ama-9 kg. Manje ngisaqhubeka nokuthatha lesi sidakamizwa ngidle nokudla. "
U-Irina, oneminyaka engama-40 ubudala, eMoscow: "Udokotela obeletha nge-endocrinologist unikeze i-Glucofage Long. Wayithatha izinyanga eziyi-10. Akazange aqaphele noma yikuphi ukuthuthuka ezinyangeni ezi-3 zokuqala, kodwa-ke ukuhlolwa kwakhe kwaveza ukuthi inani loshukela egazini lalingaphansi kunangaphambi kokwelashwa. Yebo, futhi isifiso sami sokudla sehlile, kancane wehlise isisindo vele. "
Odokotela babuyekeza i-Glucophage ne-Glucophage Long
USergey, oneminyaka engama-45 ubudala, ongoti wezokuqina kwemvelo: "Ngikholwa ukuthi i-Glucofage iyikhambi elihle futhi eliqinisekisiwe leminyaka. Ngiyibhekela kakhulu iziguli zami ezinesifo sikashukela. Sisiza nabantu abakhuluphele. Ngaphezu kwalokho, umuthi unezindleko ezingabizi."
U-Oleg, oneminyaka engama-32, odokotela abasebenza nge-endocrinologist: "I-Glucophage Long iyisidakamizwa esihle kakhulu kubantu abanesifo sikashukela sohlobo lwe-2. Ifanelekile nakubantu abanokukhuluphala. Ngibhala ngaphezu kokudla. Imiphumela emibi yamaphilisi asebambe isikhathi eside ayijwayelekile kakhulu kuneGlucofage."
