Ungayisebenzisa kanjani isidakamizwa i-Glyformin 1000?

I-Gliformin 1000 iyisidakamizwa esisebenzayo ekwelapheni isifo sikashukela esinga-insulin-2. Ilawula ngempumelelo i-glycemia, ivimbela ukuthuthukiswa kwezinkinga zesifo sikashukela.

Igama Lezwe elingafanele

I-Metformin.

I-Gliformin 1000 iyisidakamizwa esisebenzayo ekwelapheni isifo sikashukela esinga-insulin-2.

I-ATX

A10BA02

Khipha amafomu nokwakheka

Ithebhulethi ngayinye iqukethe i-1000 mg ye-metformin hydrochloride, isakhi esisebenzayo somuthi. Ngaphezu kwalokho, izakhi ezivimbela i-caking kanye nokwephulwa kwesakhiwo somuthi zengezwa ekwakhiweni kwalo muthi.

Isenzo se-Pharmacological

Inqanda izinqubo ze-gluconeogenesis ezicutshini zesibindi futhi yehlisa ukuqina kokufakwa kweglucose. Iqhakambisa izinqubo zokusebenzisa okuphathelene nalokhu kwento esebenzayo egazini. Kwandisa ukwanda kwezicubu zomzimba kuyi-insulin.

I-Metformin ayizithinti izinqubo zokwenziwa kweglucose futhi ayizibangeli iziqephu ze-hypoglycemia. Isiza ukunciphisa isisindo somzimba, ngakho-ke umuthi usetshenziswa ngempumelelo ekunciphiseni isisindo.

I-Metformin inciphisa umsebenzi we-fibrin.

I-Pharmacokinetics

Ngemuva kokuphathwa ngomlomo, lo muthi udonswa kancane kancane usuka endaweni yokugaya ukudla. I-Bioavailability icishe ibe ngama-60%. I-plasma okuhlukunyezwa okuphezulu ifinyelelwa cishe amahora angama-2,5 ngemuva kokungeniswa. Akubophele amaprotheni e-plasma. Imithi inganqwabelana emithanjeni, izicubu zomsipha, izinso nesibindi.

Kuthululwa kungashintshiwe yizinso ezivela emzimbeni. Isikhathi lapho inani lomuthi lincishiswa emzimbeni ngesigamu ngabantu abahlukile ukusuka ehoreni elilodwa nohhafu kuya emahoreni ayi-4,5. Ukuqanjwa kwesidakamizwa kungenzeka ngokulimala okunamandla kokulimala kwezinso.

Izinkomba zokusetshenziswa

Lo muthi ukhonjiswa ukusetshenziselwa ushukela ongaxhomekeli ku-insulin (ngokuya ngokulungiswa okungondlekile komzimba, inhlanganisela yesifo sikashukela nesisindo ngokweqile).

IGlyformin 1000 ikhonjiswa ukusetshenziselwa ushukela ongaxekile ku-insulin.

Contraindication

Kuyavumelaniswa ezimweni ezinjalo:

• ketoacidosis;
• ikhefana ne-precoma;
• ukwehluleka kwezinso okwenzeka kakhulu;
• izifo ezikhuluphayo ezingadala ukulimala kwezinso;
• ukomisa obunzima obangelwa ukuphalaza nohudo;
• i-pathologies enzima yokutheleleka;
• isimo esibuhlungu sendlala yomoya-mpilo, ukwethuka;
• izifo zamaphaphu ne-bronchi;
• i-pathologies eholela ekuthuthukiseni indlala ye-oxygen oxygen, kufaka phakathi i-asthma, ukuhluleka kokuphefumula kanye nokwehluleka kwenhliziyo;
• ukungenelela okunzima nokulimala;
• izimo ezidinga i-insulin;
• ukungasebenzi kahle kwesibindi;
• ubuthi obudakayo obukhulu, ukudakwa okungapheli;
• ukukhulelwa nesikhathi sokuncelisa;
• hypersensitivity ku-metformin;
• ukusetshenziswa kwezidakamizwa ze-radioisotope kanye nama-ejenti wokuqhathanisa ukuhlolwa kwe-x-ray nokuhlolwa kwe-magnetic resonance;
• ukudla okuncishisiwe kwekhalori

Umuthi ubhekene ne-ketoacidosis.

Umuthi uphambaniswe ku-coma nedlozi.

Umuthi u-contraindication ku-pathologies enzima yokutheleleka.

Umuthi uphambaniswe nokuphelelwa ngamandla okubangelwa ukuphalaza nohudo.

Ekulimazeni kokuqina kwezinhlungu, i-Glyformin 1000 i-contraindication.

Ngokuphulwa okukhulu kwesibindi, i-Glyformin 1000 iyaphikiswa.

Ngokuya ekudleni ngenani elincishisiwe lama-kilojoule, ukuthatha i-Gliformin 1000 kuqinisekisiwe.

Ngokunakekela

Kubekelwe abantu abanobungozi obukhulu bokuhlakulela i-lactic acidosis.

Ungayithatha kanjani iGlyformin 1000?

Lesi sidakamizwa se-hypoglycemic singasetshenziselwa ukunciphisa umzimba. Ukuze wenze lokhu, thatha isigamu sethebhulethi (0.5 g) kabili ngosuku. Ukusetshenziswa kwesidakamizwa emithanjeni emikhulu kuholela ekufiseni ubuthi. Inkambo yokwelapha izinsuku ezingama-20. Ngemuva kwalokho bathatha ikhefu inyanga bese bephinda isifundo esifanayo. Uma uthatha ikhefu elifushane, khona-ke isiguli sakha i-adaptation ku-metformin, futhi ukusebenza kwezokwelapha kuyancipha.

Ukusetshenziswa kwesidakamizwa akushisi amafutha, kepha kusabalalisa amandla emzimbeni.

Ngoshukela

Umthamo walo muthi unqunywe ngokuhlukile. Ithathwe ngomlomo. Isikhombi sokukhetha siyinkomba ye-glycemia. Thatha iphilisi lilonke, ngaphandle kokuhlafuna. Umthamo wokulungiswa kwe-metformin ngamathebulethi ayi-2.

Kungcono ukuthi abantu asebekhulile bathathe i-1 ithebhulethi le-Gliformin 1000.

Kungcono ukuthi abantu asebekhulile bathathe i-1 ithebhulethi le-Gliformin 1000.

Ekuphendukeni okunamandla kwe-metabolic, umthamo wale ejenti uyancipha.

Imiphumela emibi yeGliformin 1000

Ngokuphula irejimeni lokuphatha kanye nomthamo, imiphumela emibi ehlukahlukene kungenzeka.

Amapheshana wesisu

Ukuvela kwenhliziyo isicanucanu nokuhlanza. Iziguli zingaphazamiseka ukunambitheka okubukhali okungathandeki kwensimbi esemgodini womlomo. Kwesinye isikhathi ukuthatha i-Gliformin kuholela ekwehleni okubukhali kwesifiso sokudla, ukuthopha.

Lezi zimpawu zingancishiswa ngama-antacid kanye nama-antispasmodics.

Izitho zeHematopoietic

Ezimweni ezingavamile, ukuthatha lo muthi kubangela i-megaloblastic anemia.

Ngasohlangothini lwe-metabolism

I-Metformin ingadala i-malabsorption ye-vithamini B12 (cyanocobalamin).

Ezimweni ezingavamile, kubangela i-lactic acidosis. Lesi simo sidinga ukuyekiswa kokwelashwa.

Imiphumela emibi yeGliformin 1000 - ukubonakala kwenicanucanu nokuhlanza.

Kwesinye isikhathi ukuthatha i-Gliformin kuholela ekwehliseni okukhulu kokudla.

Ezimweni ezingavamile, ukuthatha lo muthi kubangela i-megaloblastic anemia.

Umphumela ojwayelekile kakhulu we-metformin, ikakhulukazi ekuqaleni kokwelashwa, yi-hypoglycemia.

Ngokuvela komzimba, ukuqhuma kwesikhumba kuvame ukuvela.

Kusuka ohlelweni lomchamo

Akukhonjwa.

Uhlelo lwe-Endocrine

Umphumela ojwayelekile kakhulu we-metformin, ikakhulukazi ekuqaleni kokwelashwa, yi-hypoglycemia. Kuqala kungazelelwe futhi kubonakaliswa yi-pallor, ukukhathazeka, ukubonakala kokujuluka kokubandayo, ukudideka. Esikhathini sokuqala sokukhula kwakhe, isiguli singamisa lesi simo ngokudla isilinganiso esincane soshukela.

Nge-hypoglycemia enzima, isiguli siphelelwa amandla. Kungenzeka ukumkhipha kulesisimo esiyingozi kuphela ngaphansi kwesimo seyunithi yokunakekelwa okuqinile.

Allergies

Ngokuvela komzimba, ukuqhuma kwesikhumba kuvame ukuvela.

Umthelela ekhonweni lokulawula izindlela

Ngoba umuthi uyakwazi ukubangela i-hypoglycemia, ngesikhathi sokwelashwa akudingekile ukushayela imoto nezinqubo eziyinkimbinkimbi kubantu abathambekele ekwehlekeni okukhulu kwamazinga kashukela egazini.

Imiyalo ekhethekile

Ngesikhathi sokwelashwa, umsebenzi wezinso kufanele ubhekelwe ngokuqhubekayo. Uma ubuhlungu bemisipha bukhona, ihlungu legazi le-lactate liyahlolwa. Kanye njalo ezinyangeni eziyisithupha, inani le-creatinine liyahlolwa. Ngokwanda kokuhlungwa kwalokhu, akukho mithi ebekiwe.

Ezinsukwini ezi-2 ngaphambi nangemva kokusebenzisa i-radiography usebenzisa ama-ejenti ahlukile, lo muthi kufanele ungafakwa ngaphandle.

Ngesikhathi sokwelashwa, umuntu kufanele wenqabe ukuphuza utshwala neminye imikhiqizo equkethe.

Ngesikhathi sokwelashwa, umuntu kufanele wenqabe ukuphuza utshwala neminye imikhiqizo equkethe.

Ukuhlaselwa yisinambuzane akukhona ukweqa ukwelashwa.

I-Glyformin Prolong ayinawo umehluko omkhulu kuma-pharmacodynamics nakuma-pharmacokinetics.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Ngesikhathi sokukhulelwa, i-metformin iyakhanselwa, futhi isiguli sinqunyelwe ukwelashwa kwe-insulin. Lesi sidakamizwa asinconywa kwabesifazane abakhulelwe ngenxa yokuntuleka kolwazi ngokuphepha kwalo kwesibeletho. Uma kunesidingo, ukusetshenziswa kwe-metformin ngesikhathi sokuncelisa kudluliselwa kuxutshwe ngezinto zokwenziwa.

Ukuyalela uGliformin ezinganeni eziyi-1000

Ukunquma izingane ngalo muthi akunconyiwe.

Isicelo sokusebenza kokulimala kwezinso

Kuyadingeka ukuqapha ngokucophelela ukufundwa kwe-glucose ne-lactate yegazi.

Sebenzisa umsebenzi wesibindi okhubazekile

Ngenxa yokuphazamiseka kwesibindi, ama-lactate indices kufanele abhekelwe kakhulu.

Lesi sidakamizwa asinconywa kwabesifazane abakhulelwe.

Ukunquma izingane ngalo muthi akunconyiwe.

Kuyadingeka ukuqapha ngokucophelela ukufundwa kwe-glucose ne-lactate yegazi.

Ngenxa yokuphazamiseka kwesibindi, ama-lactate indices kufanele abhekelwe kakhulu.

Sebenzisa ebudaleni

Kunconywe ukunciphisa umthamo ukuze ube okungenani okusebenzayo.

I-Overdose ye-Glyformin 1000

I-overdose ye-metformin ingadala i-lactic acidosis enobunzima obukhulu bokufa. Isizathu sokuthuthuka kwalesi simo ukuqoqwa kwendaba ngenxa yokusebenza kabi kwezinso. Uma isiguli singalutholi usizo, ukwaziwa kuqala kuphazamisekile, bese kuba nethokomala.

Lapho kuvela izimpawu ze-lactic acidosis, ukwelashwa kwe-metformin kunqanyulwa ngokushesha. Isiguli silaliswa esibhedlela. I-Metformin ingaqedwa ngokushesha emzimbeni ngokusebenzisa i-dialysis.

Ukuxhumana nezinye izidakamizwa

Umsebenzi owengeziwe we-hypoglycemic ubonwa lapho uphuza umuthi kanyekanye no:

• amalungiselelo aqukethe ama-sulfonylurea ahlukahlukene ahlukahlukene;
• insulin;
• I-Acarbose;
• izidakamizwa ezingezona ezibangelwa ukuvuvukala;
• Ama-inhibitors e-MAO, ACE;
• Clofibrate kanye nokuphuma kwayo;
• ICyclophosphamide;
• beta-blockers.

Umuthi uthuthukisa umsebenzi we-hypoglycemic nokusetshenziswa okuhlangene kwezidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala.

Ukwehla komphumela we-hypoglycemic kubonakala ngenkathi kuthathwa:

• izidakamizwa ze-glucocorticosteroid;
• izindlela zokuvimbela inzalo ngomlomo;
• ama-audiathomimetic agents
• I-Glucagon;
• ama-analogu zokwenziwa ama-hormone e-thyroid;
• ama-diuretics ochungechunge lwe-osmotic ne-loop;
• I-Phenothiazine kanye nokuphuma kwayo;
• Ukuqondanisa kanye nokususelwa kwe-nicotinic acid.

Umuthi uyakwazi ukwenza buthaka umsebenzi wama-anticoagulants, ikakhulukazi okuphuma ku-coumarin.

Ukuhambisana notshwala

Imiyalo ikhombisa ukuthi umuthi awuhambisani notshwala, ngoba ubangela i-lactic acidosis ngokuhlangana notshwala.

Ama-Analog

Izichasiso zalo muthi yilezi:

• IGlucophage;
• Siofor;
• I-Metformin;
• IFomu.

Imibandela yekhefu lekhemisi

Umuthi udilizwa kuphela ngemuva kokwethulwa komyalelo.

Glyformin 1000 Intengo

Intengo ephakathi yalo muthi ingama-ruble ayi-160. ama-10 ama-PC.

Izimo zokugcina zomuthi

Gcina endaweni emnyama, kude nezingane.

Isikhathi sokuphelelwa yisikhathi

Ilungele ukusetshenziswa kungakapheli izinyanga ezingama-24.

Umkhiqizi

Ikhiqizwe yi-Akrikhin Chemical and Pharmaceutical Combine JSC, eRussia.

I-analog ye-Glyformin 1000 - Glucophage.

I-analog yeGlyformin 1000 nguSiofor.

I-analog yeGlyformin 1000 yiMetformin.

I-analog yeGlyformin 1000 ifomu.

Ukubuyekezwa mayelana ne-Gliformin 1000

Odokotela

U-Inna, i-endocrinologist, eneminyaka engama-50 ubudala, eMoscow: "Lesi sidakamizwa sinqunyelwe iziguli ezinesifo sikashukela sohlobo 2 esinobunzima bokugcina izinga elifanele kakhulu le-glycemia. Ukwelashwa kunomthelela omuhle, ushukela wegazi ubuyela kokujwayelekile."

U-Irina, oneminyaka engama-45 ubudala, udokotela ojwayelekile, uNizhny Novgorod: "Ngokulungiswa kwesisindo, ngibeka amaphilisi weGliformin 1000 ngokuhlangana nokudla okuphansi kwe-carb kanye ne-calorie ephansi. Lokhu kukuvumela ukuthi uguqule isisindo somzimba futhi uvikele ukukhula kwesifo sikashukela. Iziguli zibekezelela ukwelashwa okunjalo futhi ziyaneliswa. imiphumela yayo.

Iziguli

U-Ilya, oneminyaka engama-52, eMoscow: "Ngosizo lwamacwecwe e-Gliformin, kungenzeka ukulawula kahle inkomba kashukela. Ngabona ukuthi kusukela ekuqaleni kwezokwelapha ngangizizwa ngingcono, ngaphelelwa ukoma, umfutho wegazi wami ubuyela esimweni esijwayelekile."

USvetlana, oneminyaka engama-45, u-Ivanovo: "Ukuthatha la maphilisi kwenza sikwazi ukulawula isifo sikashukela nokuvikela ukwanda koshukela. Ngiphuza amaphilisi nsuku zonke futhi ngibabekezelele kahle."

Ukulahlekelwa isisindo

UTamara, oneminyaka engama-38 ubudala, eSt.