I-Avelox 400 kwifomu lethebhulethi nesixazululo isetshenziselwa ukulwa nezifo ngesilinganiso esiphansi sokumelana nemiphumela eyonakalisayo yento esebenzayo.
Ukusetshenziswa okungalawulwa kwesidakamizwa kungadala imiphumela emibi eminingana, ngakho-ke, ukubonisana nodokotela kuyadingeka, kucatshangelwa zonke izici zomzimba wesiguli lapho kunquma.
Igama Lezwe elingafanele
I-Moxifloxacin - igama lento esebenzayo yesidakamizwa.
I-ATX
I-J01MA14 - ikhodi yokuhlukaniswa kwamakhemikhali we-anatomical and therapeutic.
Khipha amafomu nokwakheka
Kunezinhlobo ezimbili zemithamo ye-ejenti elwa namagciwane.
Amaphilisi
Umuthi wenziwa emaphaketheni eseli amathebulethi ayi-5 noma ayi-7 kulinye lazo. Ukwakheka kwophiko lwezidakamizwa kufaka i-0.4 g yento esebenzayo.
Izibhebhe zihlanganiswa ngefilimu futhi zinesimo sokufiphala.
Isixazululo
Ku-1 ml yesidakamizwa esefomini lomthamo uketshezi iqukethe i-1.6 mg ye-moxifloxacin. Umuthi wenzelwe ukumiliselwa (ukuphathwa kwe-intravenous).
Kukhiqizwa isixazululo emabhodleleni, isilinganiso sawo singama-250 ml.
Isenzo se-Pharmacological
I-quinolone antibiotic isetshenziselwa ukwelapha izifo ezingelapheki futhi ezingalapheki.
Izinzuzo zokusebenzisa umuthi:
- Into esebenzayo ivimbela ukwakheka kwamaprotheni kumaseli wama-pathogen, okuholela ekuvinjelweni ukukhula kwesibalo sawo.
- Ukusetshenziswa kwe-Avelox isikhathi eside akunamphumela omubi esibindini.
- Umuthi uyasebenza uma kuqhathaniswa namagciwane atypical kanye namagciwane angena gram.
Umuthi awunqunyelwe uma kwenzeka ukuvuvukala okubangelwa izingqinamba ze-coagulase-negative staphylococci, ezilwa kakhulu ne-methicillin.
I-Pharmacokinetics
Ngemuva kokuphathwa ngomlomo, isakhi esisebenzayo singenelwa egazini kusuka ku-rectum ngama-90%. Ungasebenzisa ithuluzi kungakhathalekile isikhathi sokudla kakhulu, njengoba lesi sici asithinti izinga lokufakwa kwe-moxifloxacin.
Ngemuva kokuphathwa komoya okuphathelene nomuthi, ukuqoqwa okuphelele kwento esebenzayo kubhekwa ngemuva kwemizuzu eyi-10-15. I-Moxifloxacin ibopha amaprotheni egazi (i-albhamuin) ngama-40%.
Ama-Metabolites adotshwa yizinso kanye nomchamo futhi ngenani elincane elinamafu.
Izinkomba zokusetshenziswa
Umuthi ubekiwe phambi kwe-pathologies elandelayo:
- ukuthuthukiswa kokuvuvukala endlebeni (i-otitis media) ne-sinusitis;
- ukutheleleka kwesikhumba nezakhiwo ezi-subcutaneous;
- ifomu elingamahlalakhona kwe-bronchitis ngokumelene nesizinda sokuvama kakhulu;
- inyumoniya
- inqubo yokutheleleka ezithweni ze-pelvic (i-salpingitis);
- izifo ezithathelwana ngocansi (chlamydia, ureaplasmosis).
Imvamisa, umuthi ubekelwa ukuvimbela izinkinga ezithathelwanayo ngemuva kokuhlinzwa.
Contraindication
Akunconyelwe ukusebenzisa umuthi ezimweni ezilandelayo:
- izifo zesistimu yenhliziyo, kufaka phakathi i-arrhythmia kanye ne-ischemia esibuhlungu;
- izilonda zohlelo lwezinzwa;
- i-organic lactose ukungabekezeleli;
- umsebenzi wesibindi okhubazekile.
Ngokunakekela
Akufanele isetshenziswe ezigulini ezithambekele ekuqulekeni futhi zinomlando we-psychosis.
Ungayithatha kanjani i-Avelox 400
Umuthi usetshenziselwa kuphela ukuphathwa kwe-intravenous, njengoba imijovo ye-intramuscular ibangela ubuhlungu obukhulu.
Imvamisa yezinqubo isikhathi esisodwa ngosuku.
Ukuqapha ngokucophelela ukugxilwa kwe-glucose egazini ngesikhathi sokwelashwa ne-Avelox kuyadingeka ukuze kugwenywe i-dysglycemia.
Umuthi ngendlela yamathebulethi uqala ukuthathwa ngemuva kwe-3 infusions.
Inkambo yokwelashwa ihlala isilinganiso sezinsuku eziyi-10.
Ukuthatha umuthi wesifo sikashukela
Ukuqapha ngokucophelela ukugxilwa kwe-glucose egazini ngesikhathi sokwelashwa ne-Avelox kuyadingeka ukuze kugwenywe i-dysglycemia.
Imiphumela emibi ye-Avelox 400
Umuthi ungadala imiphumela eminingi engathandeki emzimbeni.
Amapheshana wesisu
Iziguli zivame ukuhlaselwa yisifo sohudo nokuhlanza.
Isistimu yezinzwa ephakathi
Ukuphazamiseka kwe-Gait ngenxa yesiyezi kungenzeka, ezimweni ezingavamile eziholela ekulimaleni ngenxa yokuwa, ikakhulukazi uma kukhulunywa ngeziguli esezikhulile.
Ngaphezu kwalokho, amazwe acindezelayo aqala futhi kukhuphuke izinga lokukhathazeka.
Kusuka ezicutshini zemisipha
I-Arthralgia akuvamile ukwenzeka.
Izitho zeHematopoietic
ILeukopenia kwesinye isikhathi iyabonakala.
Kusuka ohlelweni lokuphefumula
Ukuvinjwa komsebenzi wokuphefumula nokukhwehlela okunzima kungenzeka.
Engxenyeni yesikhumba
Ezimweni ezingavamile, kuqhamuke i-rash.
Kusuka ohlelweni lwezitho zofuzo
Iziguli zikhononda ngokuchama kaningi.
Kusuka ohlelweni lwezinhliziyo
Ukuphazamiseka kwesigqi senhliziyo kuwuphawu lweziguli eziningi.
Ngasohlangothini lwe-metabolism
I-Hypoglycemia akuvamile ukwenzeka.
Engxenyeni yesibindi ne-biliary
Ukukhiqizwa okusebenzayo kwama-enzyme kuyabonakala.
Allergies
Ukwethuka kwe-anaphylactic kungenzeka ngokumelene nesizinda se-hypersensitivity kwento esebenzayo.
Umthelela ekhonweni lokulawula izindlela
Umuthi unciphisa ukunakwa kokunakwa, ngakho-ke akufanele usebenzise ithuluzi uma isiguli sishayela imoto nsuku zonke.
Imiyalo ekhethekile
Kubalulekile ukucubungula izici ezimbalwa ngaphambi kokuqala ukwelashwa nge-antibacterial agent.
Sebenzisa ebudaleni
Kuyadingeka ukulungisa umthamo kwiziguli ezingaphezulu kweminyaka engama-65.
Ukuqokwa kwe-Avelox ezinganeni ezingama-400
Ukulimala okuhlanganayo kungenzeka, ngakho-ke kungcono ukufaka esikhundleni somuthi nge-analog.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuphela ngomuthi kadokotela lapho ngingaphuza khona amaphilisi ku-trimester yesi-II. Lapho ukuncelisa ibele kufanele kuyeke ukwelashwa i-Aveloksom.
Isicelo sokusebenza kokulimala kwezinso
Akubhaliwe.
Sebenzisa umsebenzi wesibindi okhubazekile
I-Avelox ayinconywa kwiziguli ezinomdlavuza we-cirrhosis.
I-overdose ye-Avelox 400
Abukho ubufakazi bemithamo eyeqisayo yengxenye esebenzayo.
Ukuxhumana nezinye izidakamizwa
Inqubo yokumuncwa kwe-moxifloxacin yehlisa ijubane lapho uthatha amalahle ocushiwe. Ukusetshenziswa kanyekanye kweSumamed kukhulisa umphumela wokwelapha we-Avelox.
Ngokuthulwa kwemithamo ephindaphindiwe ye-antibiotic, inani eliphakeme kakhulu le-digoxin lingakhuphuka cishe ngama-25%.
Ukufakwa kwe-antibacteric kanye nama-antacid, ama-multivitamini, amaminerali kungaphazamisa ukumuncwa kwe-moxifloxacin ngenxa yokwakheka kwama-chelate complexes ane-catova ye-polyvalent equkethwe kule mithi.
Ukuhambisana notshwala
Ungaphuzi iziphuzo eziqukethe i-ethanol uma isiguli selashwa nge-Avelox.
Ama-Analog
I-Moxifloxacin neVigamox zinomphumela ofanayo. Ukusetshenziswa kwama-analogues kumthamo wama-600 mg wesakhi esisebenzayo akubangeli izimpawu zokweqisa.
Imibandela yekhefu lekhemisi
Kudingeka incwadi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Imvamisa umuthi usatshalaliswa ngaphandle kokuthola umuthi.
Intengo ye-Avelox 400
Izindleko zomuthi okungenani ama-ruble angama-700.
Izimo zokugcina zomuthi
Umuthi olwa namagciwane ugcinwa endaweni emnyama ekushiseni kwegumbi.
Isikhathi sokuphelelwa yisikhathi
Ithuluzi ligcina izakhiwo zalo zokuphilisa isikhathi esingekho ngaphezulu kweminyaka emi-3 kusuka ngosuku lokukhiqizwa.
Umkhiqizi
Lesi sidakamizwa senziwa yinkampani yaseJalimane iBayer Pharma AT.
I-analogue yesidakamizwa ingaba yi-Vigamox yezidakamizwa.
Ukubuyekezwa mayelana ne-Avelox 400
Kunezimpendulo ezinhle nezimbi mayelana nokusebenza kwe-antibiotic.
Odokotela
U-Oleg, oneminyaka engama-50 ubudala, eMoscow
Ngokuvamile kunqunyelwe ekwelapheni kwama-venous kanye ne-lymphovenous trophic ukuphazamiseka kwesikhumba. Umuthi ulungele ukuqeda ukutheleleka kusuka emafutheni angaphansi kwama-erysipelas asezingeni eliphakeme. Uhlobo olulungele, ukungabikho kwemiphumela emibi, noma ngabe inkambo yokwelashwa ihlala izinsuku ezingama-21.
UMaria, oneminyaka engama-43 ubudala, uHl
Ngincoma ikhambi lokutheleleka kwezifo zohlelo lwezitho zofuzo. Kepha ngaphezu kwalokho, ngihlala nginquma inkambo yokwelashwa kabusha ngezidakamizwa ezisuselwa ku-lactobacilli. Imvamisa, abesifazane bakhala ngokuhlanza ngenkathi belashwa nge-Avelox. Akujabuli ngenani eliphakeme le-antibiotic.
Ungaphuzi iziphuzo eziqukethe i-ethanol uma isiguli selashwa nge-Avelox.
Iziguli
U-Olga, oneminyaka engama-25, u-Ufa
Umuthi wabekwa ngemuva kokutholwa kwe-sinusitis. Ngaphuza amaphilisi izinsuku ezinhlanu. Azange kube nemiphumela emibi. Welulama ngokushesha, ngakho-ke ngincomela wonke umuntu leli gciwane elisebenza ngezinto eziningi.
UKarina, oneminyaka engama-30, Izhevsk
Saw amaphilisi e-chlamydia. Ubhekene nokuhlanza kanye nohudo ngesikhathi sokwelashwa. Angikaze ngilinde ukuphela kwenkambo yokwelashwa. Ngeke ngithi leli thuluzi lithinta umzimba ngomzimba. Ungasisebenzisi lesi sidakamizwa ama-allergies.
