IMilgamma ilungiselelo elicetshwe ngamavithamini we-B. Lo mkhiqizo ubuyisela amangqamuzana ezinzwa, okuvumela ukuthi usetshenziswe ekwelapheni ukuphazamiseka kwemizwa okuhlukahlukene. Ama-Dragees ayangenwa kalula, futhi into ngokwayo iyadedelwa emzimbeni emahoreni ambalwa.
Igama Lezwe elingafanele
I-Benfotiamine ne-pyridoxine - igama lezinto ezisebenzayo zomuthi.
I-ATX
I-A11DB - ikhodi yokuhlukaniswa kwamakhemikhali okwelashwa nokwelashwa.
I-Milgamma - isidakamizwa esicetshiswe ngamavithamini eqembu B.
Ukwakheka
Ithebhulethi eyi-1 iqukethe izinto ezisebenzayo ezilandelayo: i-100 mg ye-benfotiamine nenani elifanayo le-pyridoxine hydrochloride (Vitamin B6). Ekwenzeni izithako ezengeziwe ezengeziwe ezisetshenziswayo:
- i-microcrystalline cellulose;
- omega-3-glycerides;
- i-povidone;
- i-colloidal silicon dioxide;
- i-carmellose sodium;
- i-talcum powder.
Igobolondo lifaka:
- sucrose;
- igobolondo;
- i-calcium carbonate;
- i-acacia gum;
- titanium dioxide;
- isilika;
- isitashi sommbila;
- glycerol;
- i-macrogol;
- i-polysorbate;
- glycol wax.
Ku-1 pack yeseli kuqukethe amaphilisi ayi-15.
Isenzo se-Pharmacological
I-Benfotiamine (i-fat-soluble derivative of thiamine) ithuthukisa umzimba we-carbohydrate metabolism. Umuthi ubandakanyeka ekudleni kwamaprotheni ezingeni lamaselula, unomthelela ekufakweni kwamafutha okujwayelekile, usebenza njenge-antioxidant enhle kakhulu. Uhlobo lwe-neuroactive lwe-thiamine yi-thiamine triphosphate. Ngenxa yalokhu, ukusebenza okujwayelekile kokufakelwa izinzwa kuyaqinisekiswa, umuthi unomphumela we-analgesic, uthuthukisa ukuhamba kwegazi.
I-Pyridoxine isebenza njenge-cofactor (i-non-protein protein), ebamba iqhaza ezinqubweni eziningi ze-enzymatic ezenzeka kwezicubu zezinzwa. IVithamini B6 isetshenziswa njenge-ejenti yokuqinisa ekwelapheni izifo eziwohlokile futhi ezingavuvukalanga, ukuphazamiseka kokusebenza okujwayelekile kwemishini yokushayela yezimoto.
I-Pyridoxine ithuthukisa ukwakheka kwama-neurotransmitters anjenge-adrenaline, i-norepinephrine, i-dopamine, i-histamine. Into eyenza imisebenzi efana:
- i-decarboxylation yama-amino acid, ukuguquguquka kwabo;
- ukuvimbela ukukhiqizwa ngokweqile kwe-ammonia;
- ukuvuselelwa kokuxhumeka kwezinzwa.
I-Pharmacokinetics
IBenfotiamine idonswa umgudu wamathumbu emathunjini. Ukuqoqwa okuphezulu kwento kubonwa ihora eli-1 ngemuva kokuthatha umuthi. Uhlobo olunamafutha amaningi ka-vithamini B1 lumunca umzimba ngokushesha okukhulu kunethiamine encibilikiswa amanzi. Le nto iguqulwa i-thiamine diphosphate ngemuva kwe-biotransformation. Ngemuva kwalokho, kuyafana ne-thiamine. I-Thiamine diphosphate iyi-coenzyme ye-pyruvate decarboxylase, ibandakanyeka ekuthambekeni.
Iningi le-pyridoxine ligxilwe emgudwini ongaphezulu wesisu ngesikhathi sokufakelwa kokunye. Uma isisegazini, iguqulwa ibe yi-pyridoxalphosphate futhi yakhe isibopho esiqinile se-albhamuin. Ngaphambi kokungena esitokisini, into i-hydrolyzed yi-alkaline phosphatase.
Womabili la mavithamini akhululwa nge-urea. I-Thiamine igxilwe ngokuphelele ngesigamu kuphela, konke okunye kukhishwa ngendlela yoqobo. IBenfotiamine isuswe isigamu egazini ngemuva kwamahora angama-3.6, ne-pyridoxine - ngemuva kwamahora ayi-2-5.
Yini esiza amaphilisi e-Milgma?
Umuthi ubesebenza ngempumelelo ekwelashweni kwezifo ezilandelayo:
- i-neuritis ne-neurosis okubangelwa ukuntuleka kwamavithamini B1 no-B6;
- i-polyneuropathy, i-neuropathy;
- ama-syndromes ama-radicular;
- i-myalgia;
- i-herpes zoster;
- i-retrobulbar neuritis;
- ganglionitis;
- izilonda zenzwa yobuso;
- i-plexopathy;
- i-lumbar ischalgia;
- izilonda ze-systemic neurological;
- i-radiculopathy.
Ithuluzi lisiza ukuqeda ama-cramps ngesikhathi sokulala, ama-syndromes ahlukahlukene wemisipha.
Contraindication
Umuthi awuvunyelwe ukusetshenziswa emacaleni amaningi anjalo:
- hypersensitivity ezingxenyeni ngazinye zesidakamizwa;
- ukwehluleka kwenhliziyo, kufaka phakathi isigaba sokubuyiselwa kwemali;
- ebuntwaneni.
Imithamo nokuphathwa kwamaphilisi eMilgamma
Kunconywa ukuthatha umuthi ngemuva kokudla, amaphilisi ama-1-2 izikhathi ezi-3 ngosuku. Umkhiqizo kumele ugwinywe ngenani elikhulu loketshezi. Isikhathi sokwelashwa singamaviki ama-4.
Ngoshukela
Kusetshenziswa amaphilisi eMilgma ekwelapheni i-neuropathy yesifo sikashukela. Isifo sikashukela singawusebenzisa umuthi 1 izikhathi ezintathu ngosuku, uma kunesidingo sokuqeda ukuhlaselwa kobuhlungu. Njengokwelashwa kokulungiswa, ungathatha ithebhulethi engu-1 ngosuku.
Umuthi uphambaniswe nokwehluleka kwenhliziyo.
Imiphumela emibi yamathebulethi iMilgamma
Amapheshana wesisu
Akuvamile ukuthi, isicanucanu kwenzeka ngenkathi uthatha umuthi, kwesinye isikhathi uphenduka wokuhlanza.
Isistimu yezinzwa ephakathi
Njengomphumela wokusetshenziswa kwesidakamizwa isikhathi eside (izinyanga ezingaphezu kweziyi-6), i-peropheral sensory neuropathy ingakhula. Ukuvela kwezimpawu ezinjengokuthi:
- ukuhlaselwa ikhanda;
- isiyezi, ukudideka;
- ukukhuphuka kokujuluka.
Kusuka ohlelweni lwezinhliziyo
Kwezinye izimo, umuthi uvusa ukuthuthukiswa kwe-tachycardia.
Kusuka emasosheni omzimba
Lokhu kusabela okulandelayo okungahle kwenzeke kubantu ku-hypersensitive to the drug:
- ukuqunjelwa kwesikhumba, ukulunywa, i-urticaria, ukuphefumula komoya;
- I-edema ka-Quincke ne-anaphylactic ukushaqeka.
Umthelela ekhonweni lokulawula izindlela
Umuthi awuthinti izinga lokuphendula futhi awukuphazamisi ukugxilisa ukunakwa okudingekayo ukulawula izindlela.
Allergies
Ngokuphikisana nesizinda sokuthatha umuthi, izinduna zingavela. Kwesinye isikhathi ubomvu obukhulu besikhumba bubonwa, futhi umuzwa ovuthayo uzwakala kwezinye izindawo zesikhumba.
Imiyalo ekhethekile
Isabelo sezingane
Ngenxa yokuntuleka kwedatha emtholampilo ngemiphumela yesidakamizwa emzimbeni wezingane, umuthi awubekelwe izingane.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umuthi uqukethe i-100 mg ye-pyridoxine, ephindwe amahlandla ama-4 kunokudla kwama-Vitamin nsuku zonke ngesikhathi sokukhulelwa. Ngalesi sizathu, ochwepheshe abalunqamuleli umuthi kwabomama abakhulelwe nababambisayo.
Ukweqisa
I-overdose iyivelakancane kakhulu. Ibonakala ngendlela yemiphumela ye-neurotoxic eqhubeka isikhashana. Uma umthamo owandisiwe wesidakamizwa uthathwa njalo izinyanga eziyisithupha noma ngaphezulu, isiguli singathola i-sensor neuropathy, engahle ihambisane ne-ataxia. I-overdose ibangela ukuquleka.
Ukuxhumana nezinye izidakamizwa
Kubalulekile ukucabanga ngezinto ezinjalo:
- I-Thiamine yenziwe sacates.
- Umuthi uLevodopa unciphisa ukusebenza kahle kokwelashwa ngevithamini B6.
- Yehlisa umphumela wezinto zama-vitamin redox, i-riboflavin, phenobarbital, metabisulfite.
- Ukwehla kwe-thiamine kunomthelela ethusi. Into esebenzayo yomenzeli iyeka ukusebenza uma i-pH inkulu kune-3.
- Ama-antioxidants anciphisa izinga le-Photolysis, i-nicotinamide - iyanda.
Nge-overdose yesikhathi eside, isiguli singathola i-neuropathy, ehambisana ne-ataxia.
Ukuhambisana notshwala
I-Ethanol ibangela ukuntuleka kwe-Vitamin B6. Ukuphuza utshwala ngenkathi ukwelashwa akunconywa.
Ama-Analog
IMilgamma Compositum iyatholakala ngesimo sesisombululo somjovo. Izidakamizwa ezilandelayo ze-analogue zikhona: Neuromultivit, Polyneurin, Neurobeks, Neurorubin, Combilipen, Triovit, Neurobeks Forte.
Uyini umehluko phakathi kwamaphilisi namaphilisi weMilgma?
Umuthi kuzo zombili izinhlobo zemithamo unomphumela ofanayo wokwelapha. Amathebulethi athathwa phambi kokuphazamiseka kwemizwa okubangelwa ukuntuleka kwamavithamini e-B. Ama-dragees asebenza kangcono ekwelapheni i-neuritis, neuralgia.
I-Triovit iyi-analogue yeMilgamma.
Imibandela yekhefu lekhemisi
IMilgma ibhekisela emithini engaphezulu kwe-counter.
Kubiza malini?
Intengo ephakathi yeMilgamm ngesimo se-dragee ngama-ruble ayi-1000.
Izimo zokugcina zomuthi
Umuthi kufanele ugcinwe emazingeni okushisa afinyelela ku + 25 ° C, ungafinyeleleki ezinganeni.
Isikhathi sokuphelelwa yisikhathi
Umuthi ugcina izindawo zawo zokuphulukisa iminyaka emi-5.
Umkhiqizi
Umuthi ukhiqizwa yinkampani yaseJalimane iWorwag Pharma.
Ukubuyekezwa
Odokotela
UVictor, oneminyaka engama-50, eMoscow
Umuthi ukhombise ukusebenza ngempumelelo ekwelapheni izinhlungu emuva, i-osteochondrosis. Ngemuva kokuthatha ivithamini, iziguli zami zihamba kangcono. Ukudonswa kwethuluzi kuphela izindleko eziphakeme.
UDmitry, oneminyaka engama-45 ubudala, eSt
Ngibeka iMilgma ezigulini ezine-neuralgia. Umuthi usiza abantu ezimweni ezicindezelayo.
Iziguli
UNatalya, oneminyaka engama-26 ubudala, eSt
Wathatha uMilgma ngenkathi elapha i-neuralgia ye-intercostal. Ama-Dragees alungele ukuthatha, ngoba zingahlala zithwalwa nawe. Ungathenga umuthi kunoma iyiphi ikhemisi. Akuwenzi umonakalo emzimbeni.
UMira, oneminyaka engama-25 ubudala, Kazan
Udokotela unikeze umuthi wokwelashwa okuyinkimbinkimbi kwe-osteochondrosis yomgogodla we-thoracic. Ukukhathala kwemisipha kuhambile, izinhlungu zinciphile.
