I-Amoxiclav - umuthi obanzi obanzi, i-antibiotic, i-blockaase lactamase blocker ekhethiwe. Inezindlela eziningi zemithamo. Umuthi usetshenziswa ku-gynecology, dermatology, urology kanye ne-otolaryngology. Izindlela zokwelapha zihambisana nemithi ejwayelekile futhi kuhloswe ngazo ukuthuthukisa isimo esivamile sesiguli.
Igama
Igama elingabambeki emhlabeni jikelele (i-INN) yi-amoxicillin + clavulanic acid, negama layo lokuhweba yi-Amoxiclav 1000.
I-Amoxiclav iyi-antibiotic, i-beta-lactamase blocker ekhethiwe, esetshenziswa ku-gynecology, dermatology, urology kanye ne-otolaryngologists.
I-ATX
Umuthi unikezwa ikhodi ye-ATX yomuntu ngamunye - i-J01CR02. Inombolo yokubhalisa - N012124 / 02 kusuka ku-07.24.2010.
Khipha amafomu nokwakheka
I-antibiotic itholakala ngesimo samathebulethi ne-liquid soluble powder. Ukumiswa namathebulethi ekwakhiweni kunento efanayo esebenzayo - i-amoxicillin. I-Clavulanic acid (usawoti we-potassium) iyisakhi sesibili esisebenzayo.
Amaphilisi
Ifomu lokukhishwa kwethebhulethi liqukethe i-1000 mg ye-amoxicillin ne-600 mg kasawoti we-potassium. Amathebulethi amhlophe okweqanda e-Biconvex awunawo ama-chamfers kanye notches, ingaphezulu bushelelezi futhi licwebezelayo. Ithebhulethi ngayinye ihlanganiswa nencibilikdi ye-membrane-film emathunjini. Umenzi uhlinzeka ngokuba khona kwezinto ezisizayo, ezibandakanya:
- i-crospovidone;
- i-croscarmellose sodium;
- i-microcrystalline cellulose;
- i-talc;
- i-colloidal silicon dioxide;
- i-magnesium stearate.
Amafutha eCastor ne-iron oxide angasebenza njengodayi, ngenxa yokuthi amaphilisi athola ilitha eliphuzi. Iphakethe ngalinye lethebhulethi liqukethe amaphilisi ayi-10. Ebhokisini lekhadibhodi lapho umuthi uthengiswa khona, kunezinhlamvu ezimbili. Imiyalo yokusebenzisa ngendlela ipheshana ikhona.
Ifomu lokukhishwa kwethebhulethi liqukethe i-1000 mg ye-amoxicillin ne-600 mg kasawoti we-potassium.
Powder
Ukumiswa okulungiselelwe kusuka ku-powder kuhloselwe ukusetshenziswa kwe-infusion. I-lyophilisate ifakiwe kuhlu lwamakhemikhali ukulungiselela isixazululo esikhishwa ngokuhlinzwa. I-Amoxicillin (1000 mg) nosawoti we-potassium (875-625 mg) akhona ekwakhiweni kwefomu lomthamo. Izinto ezingeziwe:
- i-sodium citrate;
- i-sodium benzoate;
- sodium saccharase;
- I-MCC (i-microcrystalline cellulose).
Izimbotshana zokungenela zithengiswa emabhodleleni engilazi, ngalinye lifakwe ebhokisini lekhadibhodi.
Isenzo se-Pharmacological
Umuthi ungowokulwa namagciwane eqembu le-penicillin, usawoti we-potassium akhona ekwakhiweni kwawo, esebenza njengabasiki be-beta-lactamase blockers. I-Amoxicillin ithathwa njenge-derivative ye-penisilini ye-semisynthetic. Ukwakheka kwe-clavulanic acid kuyafana nokwakheka kwama-beta-lactam antibiotic, umuthi unomphumela we-antibacterial.
I-Amoxicillin ithathwa njenge-derivative ye-semisynthetic penicillin, iwahlukanise amandla amagciwane anegram kanye nama -organic anaerobic.
Ama-ejenti we-patathogenic azwela izinto ezisebenzayo zomuthi:
- amabhakithiliya anempilo enhle;
- ama-anaerobic microorganisms (kufaka phakathi i-gram-negative ne-gram-positive).
Usawoti wePotassium ngokuhambisana ne-synticative penicillin evumela ukusetshenziswa komuthi ekwelashweni kwezifo zesifo esithathelwanayo.
I-Pharmacokinetics
Amafomu omthamo enzelwe ukuphathwa ngomlomo angena ngokushesha emgodini wokugaya ukudla. Ukuba khona kokudla esiswini akulithinti izinga lokufakwa kokumiswa kanye namaphilisi egazini. Izinto ezisebenzayo zibopha amaprotheni egazi ngama-54%, ukugxilisa okukhulu kufinyelelwa ngemuva kwemizuzu engama-50-60 ngemuva komthamo wokuqala. I-Amoxicillin ne-clavulanic acid zisatshalaliswa ngokulinganayo ezicutshini, ziyakwazi ukungena ngamathe, izicubu zamalunga nemisipha, izindunduma ze-bile, ne-prostate.
Uma kungekho ukuvuvukala ebuchosheni, isithiyo segazi-ingqondo sivimbela ukungena kwezinto ezisebenzayo. Imisuka yezakhi ezisebenzayo itholakala ubisi lwebele. Ngokwengxenye, i-metabolism yenziwa isibindi, imikhiqizo yayo ikhishwa kanye nomchamo. Ingxenye engasho lutho ishiya umzimba kanye nezindunduma namathe. Ukuqedwa kwesigamu sempilo kuthatha imizuzu engama-90.
Amafomu omthamo enzelwe ukuphathwa ngomlomo angena ngokushesha emgodini wokugaya ukudla.
Izinkomba zokusetshenziswa
Ukusetshenziswa kwe-antibiotic kwenziwa lapho kuhlonza izifo zeziguli zesimo esithathelwanayo, ezihambisana nokuthuthuka kwenqubo yokuvuvukala. Ama-causative agents alolu hlobo lwesifo angama-microorganisms azwela umuthi. Imiyalo iqukethe izinkomba ezilandelayo ezisetshenziswayo:
- izifo zokuphefumula (i-tonsillitis, sinusitis, pharyngitis);
- i-pathology yohlelo lwe-genitourinary (prostatitis, cystitis);
- izifo zepheshana lokuphefumula eliphansi (i-bronchitis engapheli futhi eyingozi, i-pulmonary pneumonia);
- izifo zohlelo lowesifazane lokuzala (colpitis, vaginitis);
- izinqubo zokuvuvukala emathanjeni nasejoyini;
- imiphumela yokulimala kwezinambuzane;
- ukuvuvukala kwepheji le-biliary (cholecystitis, cholangitis).
Ukusetshenziswa kwe-antibiotic ekwelapheni izifo ze-gynecological kukuvumela ukuthi ubuyisele i-microflora yemvelo yesitho sangasese.
Contraindication
Ukuba khona kwe-contraindication esigulini kwenza ukusetshenziswa kwezidakamizwa akunakwenzeka. Lokhu kufaka phakathi:
- i-mononucleosis yemvelaphi ethelelekayo;
- umlando we-cholestatic jaundice;
- i-lymphocytic leukemia;
- idiosyncrasy ye-amooticillin;
- iminyaka yezingane (kuze kube iminyaka eyi-10);
- hypersensitivity kuma-antibiotics.
Amacala angenhla abizwa ngokuthi ama-contraindication aphelele. Ukuphulwa okuhlobene:
- ukwehluleka kwesibindi;
- ukwehluleka kwezinso.
Ukuphulwa okuhlobene kudinga ukwamukelwa ngokucophelela ngaphansi kokuqondisa kukachwepheshe.
Ungayithatha kanjani i-Amoxiclav 1000
Uhlobo lomthamo nesikhathi sokusetshenziswa kubalwa ngawodwana. Ithebhulethi zithathwa ngaphambi noma ngemuva kokudla, isikhathi 1 ngosuku. I-lyophilisate i-soluble emanzini wokujova. Ukwehlisa i-600 mg ye-clavulanic acid, kudingeka amanzi ayi-10 ml. Isingeniso senziwa ngaphakathi, isisombululo sikhishwa kancane ngaphezulu kwemizuzu engu-2-3. Isixazululo Ready asibhekiswa eqandeni.
Umthamo wezingane
Ezinganeni ezingaphezu kweminyaka eyi-10 - 10 mg ye-clavulanic acid nge-10 kg yesisindo. Ezinganeni ezingaphansi kweminyaka eyi-10, ukusetshenziswa komuthi akuvunyelwe ngokuphelele.
Kwabadala
Isimo sansuku zonke sikasawoti we-potassium (clavulanic acid) kwiziguli ezindala yi-600 mg.
Zingaki izinsuku okufanele uthathe
Inkambo yokusebenzisa izinsuku eziyi-10. Ngesikhathi sokuvuselelwa kokuhlinzwa ngemuva kokuhlinzwa, kuyadingeka ukuthatha ifomu lethebhulethi le-antibhayoriki izinsuku ezingama-7-10.
Ukuthatha umuthi wesifo sikashukela
Ezigulini ezinesifo sikashukela, ukwelashwa kunconyelwa ukuqala ngomthamo wesigamu. Isimo sansuku zonke akufanele singeqi ku-500 mg we-amoxicillin.
Imiphumela emibi
Uhlobo lomthamo okhethwe ngokungafanele lubangela ukuthuthukiswa kweminye imiphumela emibi.
Amapheshana wesisu
Iziguli zizwa ukulahleka kokudla, isicanucanu nokuhlanza, izinhlungu zesisu nokuphazamiseka kwesisu.
Izitho zeHematopoietic
Kukhona ukwanda kwesilinganiso senhliziyo, i-thrombocytopenia, i-pancytopenia.
Isistimu yezinzwa ephakathi
Iziguli zisengozini yokuzwa isiyezi, ukukhathazeka, ukuphazamiseka kokulala, i-migraines.
Kusuka ohlelweni lomchamo
IJade ne-crystalluria zingakhula.
Allergies
E-46% yeziguli ezakhala ngemiphumela emibi kudokotela, ukungezwani komzimba kwembulwe ngendlela yokulunywa, i-urticaria ne-vasculitis. Ezimweni ezingavamile, ukwethuka kwe-anaphylactic kungahle kube khona.
Imiyalo ekhethekile
Imiyalo yokusebenzisa iqukethe imiyalo ekhethekile, ukuhambisana okuphoqelekile.
Ukuhambisana notshwala
Akukho ukuvumelana phakathi kwama-anti-antibiotic notshwala. Kwenqatshelwe ukuphuza utshwala ngenkathi ulashwa nomuthi.
Umthelela ekhonweni lokulawula izindlela
Ngesikhathi sokusebenzisa umuthi, kunconywa ukwenqaba ukushayela izimoto.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukwelashwa kwezifo ezithathelwanayo nge-antibiotic ngesikhathi sokuzala nengane kuvunyelwe ngezizathu zempilo.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukwehluleka kwe-Hepatic kungukuphikisana okuphelele.
Isicelo sokusebenza kokulimala kwezinso
Iziguli ezitholakale zinesifo sezinso zidinga ukuphathwa ngokucophelela.
Ukweqisa
Ukuvimbela ngokweqile kwenziwa ngokuhambisana ngokuphelele nayo yonke imiyalo yezokwelapha. Ukweqisa inqubo ejwayelekile yokwelapha ngezikhathi ezi-2 noma ngaphezulu kukhulisa ubungozi bokuqalwa kwezimpawu zokweqisa kwe-overdose. Lokhu kufaka phakathi isifo sohudo, ukugabha okungalawulwa, kanye nokukhathazeka ngokweqile ngokomzwelo. Iziguli azivamile ukuba nezikhwehlela.
Ayikho i-antidote ethile. Uma kwenzeka kweqa ngokweqile, isiguli sidinga ukuhlanza isisu bese sinikeza i-enterosorbent (namalahle ocushiwe).
Ukuxhumana nezinye izidakamizwa
Umuthi wokulwa namagciwane ngokuhlangana nezidakamizwa ezithile ungadala ukuqubuka kwesimo sokucasulwa kwamathumbu. I-Glucosamine, ama-antacid, ama-laxatives, ama-aminoglycosides angabambezela ukumunca umuthi. I-Ascorbic acid ngasikhathi sinye ne-antibiotic isheshisa ukumuncwa kokugcina.
Izidakamizwa ezikhuthaza ukuphuma komchamo ngokushesha, i-Allopurinol, i-Phenylbutazone kanye nezidakamizwa ezingezona ezokungezwani ne-steroidal zandisa ukugcwala kwezinto ezisebenzayo egazini. Ama-anticoagulants kanye ne-antibiotic yehlisa inkomba ye-prothrombin. Ukuhlanganiswa kwale mithi kukhethwe uchwepheshe wezempilo. I-Methotrexate ithuthukisa ubuthi be-amoxicillin. I-Allopurinol ne
Umuthi wokugomela kanyekanye ukwandisa ubungozi be-exanthema.
IDisulfiram ayihambelani nomuthi olwa ne-antibacterial. I-Rifampicin ithola imiphumela yokwelapha ye-amooticillin. Ukusebenza kwe-antibiotic kuyancipha ngokusetshenziswa okuyinkimbinkimbi komuthi ngama-macrolides, ama-tetracyclines kanye nokutholakala kwe-sulfamic acid. I-Probenecid yehlisa izinga lokuphuma kwe-amoxicillin. Umphumela wokuvimbela inzalo ngomlomo uyancishiswa.
Analogs of Amoxiclav 1000
Ama-analog ama-antibiotic asemikhakheni eyahlukene yamanani. Izindleko zemithi zincike kumenzi - okufakelwa okufuywayo okusendlini kushibhile kunasekuqaleni. Izimpawu zomuthi:
- I-Amoxiclav Quicktab. I-analogue yokwakheka inezithako ezisebenzayo ezifanayo nezangasekuqaleni, kodwa emakhenikheni omnene kakhudlwana (500 mg +125 mg). Kuyatholakala ngesimo sethebhulethi. Isicelo kungenzeka lapho kuhlonza isiguli izifo zesifo esithathelwanayo, kuhambisana nokuvuvukala. Izindleko zalo muthi zivela kuma-ruble angama-540.
- Panclave. Uhlobo lwethebhulethi lomuthi luhloselwe ukuphathwa ngomlomo, amaphilisi aqukethe 250-500 mg we-amoxicillin no-125 mg kasawoti we-potassium. Umuthi olwa ne-antibacterial usetshenziswa ku-venereology, gynecology and otolaryngology. Izindleko - kusuka kuma-ruble angama-300.
- ISultasin. I-analogue eshibhile. I-penicillin antibiotic iyatholakala njenge-lyophilisate. Ukwakheka kuqukethe i-sodium ampicillin ne-sodium sulbactam. Umuthi ukhulume ngezakhiwo ezibulala amagciwane. Izindleko - kusuka kuma-ruble angama-40.
Konke ukufaka esikhundleni kuyehluka ekuqoqweni kwezinto ezisebenzayo. Uhlobo lomthamo lukhethiwe ngamunye.
Imibandela yekhefu lekhemisi
Idinga umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Uhlu B. Ngaphandle kwencwadi kadokotela, awukwazi ukuthenga umuthi.
Malini
Intengo ephansi yesidakamizwa ama-ruble angama-90.
Izimo zokugcina Amoxiclav 1000
Ukugcinwa kwenziwa endaweni ephephile, eyomile.
Isikhathi sokuphelelwa yisikhathi
Gcina ngaphezu kwezinyanga ezingama-24.
Ukubuyekezwa kwe-Amoxiclav 1000
Odokotela
Isakova Alevtina, otolaryngologist, Samara
Umuthi uyathandwa, ukusebenza kwawo kuhlolwe isikhathi. Imiphumela emincane incane, umuthi ubekezelelwa kahle yiziguli. Intengo ephansi ihlanganisa ngokuqinisekile. Esezenzakalweni, bengihlala ngisebenzisa i-antibiotic isikhathi eside. Uhlobo lomthamo lincike ezicini zenkambo yesifo. Kubalulekile ukulandela yonke imiyalo kadokotela wakho. Amathebulethi kufanele agezwe ngamanzi kuphela, uma kungenjalo itiye, ikhofi noma iziphuzo ezinekhabhoni. Akukho ukulungiswa kwamandla okudingekayo.
Kairat Zhanatasov, uchwepheshe wezifo ezithathelwanayo, iSytytykkar
Umuthi usuzibonakalisile ekwelashweni kwezifo ze-etiology ezithathelwanayo. Iziguli azivamile ukukhononda ngemiphumela emibi, ukusabela komzimba esikhunjeni kuyaqabukela. Umuthi ohlanganisiwe unomphumela oqinile we-antimicrobial, ngaphansi kwethonya lapho amagciwane angama-gram-negative ne-gram-positive afa. Angikukhuthazi ukuphuza amaphilisi isikhathi esingaphezu kwezinsuku eziyi-10. Ukumiswa okhethekile nokunambitheka okumnandi kuthengiselwa izingane, ukwakheka kwawo kumnene futhi kuphephile.
I-Amoxiclav - umuthi obanzi obanzi, i-antibiotic, i-blockaase lactamase blocker ekhethiwe.
Iziguli
UChristina, oneminyaka engama-32, pos. I-Soviet
Umphimbo obuhlungu obungapheliyo uzenza uzizwe kabili ngonyaka. Ukwanda kwesifo kuqine kangangokuba ukudla kungabe kusenzeka. Amathoni ayashiswa, ukuqiniswa akuyilethi impumuzo. Ngawuthatha umuthi isikhathi eside ngaze ngathola udokotela i-penicillin antibiotic. Ukutholile ngomuthi wesi-Latin. Ngaphuza amaphilisi izinsuku eziyi-10, ithebhulethi elilodwa ngosuku. Izinsuku zokuqala zazikhathazekile ngezinto zokwaliwa. Izinduna ezincane zazibonakala esikhunjeni, zihlala ziluma. Ubafake ngamafutha e-antihistamine, ukusabela komzimba kudlule ngemuva kwezinsuku ezi-2.
UFedor, oneminyaka engama-41 ubudala, uNovorossiysk
Ngemuva kokuhlinzwa, waphuza i-penicillin antibiotic ngesikhathi sokuvuselela umzimba. Umuthi awuzange ufake isandla ekunciphiseni ngokushesha i-suture, kepha amakhaza ahamba ngokushesha. Waquleka ngaphambi kokuhlinzwa, ukungenelela kwakuphuthumayo, ngakho-ke akazange akwazi ukuphulukisa umkhuhlane ojwayelekile. Imiphumela emibi yayincane - isisu esidabukisayo.
