Amacwecwe e-Chlorhexidine: Imiyalo esetshenzisiwe

Ku-chemacology, kukhona ama-antiseptic kanye nama-anesthetic agents amaningi. IChlorhexidine ungomunye wayo. Amacwecwe e-Chlorhexidine ngendlela evamile ayindlela engatholakali. Kepha ama-lozenges, abizwa ngokuthi ama-lozenges, ama-lozenges aqukethe i-chlorhexidine njengoba into esebenzayo yanele emakhemisi.

Amafomu akhona akhishwe kanye nokwakheka

IChlorhexidine ingokulandelayo:

• isixazululo esihlanganisiwe (esisetshenziselwe ukuhlinza, ukuhlinza amazinyo);
• fafaza ne-aerosol (kufafazwe emphinjeni noma endaweni ebuhlungu);
• ukhilimu, amafutha noma ijeli (ube nesicelo sangaphandle nesasendaweni);
• ama-supplementories wesitho sangasese sowesifazane (anqunyelwe ukususwa kwezifo ze-gynecological);
• i-lozenges (i-lozenges noma i-lozenges esetshenziswa njenge-antiseptic ye-angina);
• i-bactericidal patch (ngamaphilisi we-chlorhexidine-soaked).

Amacwecwe e-Chlorhexidine ayindlela engekho, kepha imikhiqizo equkethe i-chlorhexidine yanele, ngokwesibonelo, i-sebidine.

Udokotela unesibopho sokukhethwa kwamafomu omuthi ngokuya ngesifo, ngoba wonke enzelwe izimo ezihlukile. Ngaphezu kwento esebenzayo, afaka ezinye izithako:

• izixazululo zifaka amanzi ahlanziwe;
• amahlumela nama-aerosols - izithasiselo zesitshalo, ipropolis, uju, uwoyela obalulekile, ama-thickeners nezixazululo;
• Ama-chlorhexidine okhilimu, okokugcoba nama-gels akhiwa ngamanzi, amagciwane, ama-moisturizer, ama-emulsifiers, ama-emollients, ama-lanolin, amavithamini.

Izinhlobo eziSolid zibhekisela kumalungiselelo wokuhlanganiswa futhi, ngaphezu kwe-chlorhexidine esebenzayo, ifaka:

• ascorbic acid (amaphilisi eSebidin);
• i-anesthetic benzocaine, i-hydrogen peroxide (i-chlorhexidine bigluconate), ama-thickeners (ama-supplementories angama-vaginal Hexoral);
• i-ejenti yokulwa nokuvuvukala i-enoxolone, i-mintol ne-ushukela esikhundleni (amaphilisi we-Anzibel);
• i-anesthetic tetracaine ne-Vitamin C (iDrill lozenges, i-Anti-Angin lozenges).

I-Chlorhexidine isesimweni sekhambi elihlanganisiwe (elisetshenziselwa ukuhlinza, ukuhlinza amazinyo).

Ama-suppositories we-Vaginal anqunyelwe ukudambisa izifo ze-gynecological.

Udokotela unesibopho sokukhethwa kwamafomu omuthi ngokuya ngesifo, ngoba wonke enzelwe izimo ezihlukile.

Igama Lezwe elingafanele

I-Chlorhexidine.

I-ATX

R 02 AA 0 5.

Isenzo se-Pharmacological

Umuthi ungoweqembu lama-antiseptics. Umphumela we-pharmacological uwumsebenzi ophikisana:

• amagciwane;
• imvubelo
• dermatophytes;
• amagciwane we-lipophilic.

I-Pharmacokinetics

Uhlobo lolo ketshezi lomuthi, lungena ngaphakathi ngemuva kokufakwa ngokungenamsoco, aluthathwa emgodini wokugaya ukudla, lukhipha ngamaphesenti angama-90 ngendle kanye no-1% ngomchamo. Ngemuva kokuthatha amaphilisi, into igcinwa kumathe kuze kube amahora angama-8-10. Uma usebenzisa i-suppository, ukufakwa okuhleliwe komuthi (ukumuncwa) akunakwa.

Yini esiza chlorhexidine

Umuthi wenza imisebenzi elandelayo:

• i-antiseptic;
• i-bactericidal;
• i-anesthetic yendawo (inhibits receptors pain);
• fungicidal (kuthinta isikhunta).

I-Chlorhexidine in amafomu ketshezi isetshenziselwa ukuvimba kanye nokwelashwa kokuguguleka komlomo wesibeletho.

I-Chlorhexidine isetshenziselwa ukuvuvukala izicubu kanye ne-tonsillitis.

I-Chlorhexidine Solution isebenza njenge-antiseptic ekwelapheni amanxeba okuhlanza nokushiswa.

I-Chlorhexidine in amafomu ketshezi isetshenziselwa ukuvimbela kanye nokwelashwa:

• I-Trichomonas colpitis;
• ukuguguleka kwesibeletho;
• ukuvuvukala kwamathani kanye ne-tonsillitis;
• Izinkinga ngemuva kokukhishwa izinyo.

Isixazululo sisebenza njenge-antiseptic ye:

• okuqukethwe kwamazinyo;
• ukunakekelwa kwangemuva kokusebenza;
• ukwelashwa kwamanxeba okuhlanza nokushiswa;
• ukubulala amagciwane ngesandla, kanye nezinsimbi zokwelapha.

Izindlela zomlomo zisetshenziselwa ukutheleleka komlomo kanye nomphimbo, masinyane ukuyeka ukuvuvukala, misa ukubonakaliswa kokuqala kwe-pathologies (gingivitis, periodontitis, stomatitis, alveolitis).

Contraindication

Ukuxhumana kokuqokwa kwezixazululo nokugcotshwa yilezi:

• hypersensitivity kwento esebenzayo;
• ukungahambisani nezinto ezengeziwe;
• isikhumba sesikhumba.

Ukuxhumana kokuqokwa kwezixazululo namafutha okugcotshwa isikhumba kuyinto yesikhumba.

Ithebhulethi ayikhonjiswa izilonda zesisu.

Amacwecwe e-Chlorhexidine afakwa ku-asthma.

Iithebhulethi azikhonjiswanga ku:

• izifo ezinzima ze-ENT;
• ukuguguleka ku-mucosa womlomo;
• isilonda sesisu;
• isifuba somoya

Ungayithatha kanjani i-chlorhexidine

Ukusetshenziswa kwamafomu ahlukile:

• izingoma zamanzi zokunisela noma ama-compress asetshenziswa izikhathi ezi-2 ngosuku;
• ekuvinjelweni kwezifo zezitho zangasese, isixazululo sifakwa ngensimbi engena esithweni sangasese ngemuva kocansi (kunconywa kanyekanye ukwelashwa kwe-pubis kanye nethanga);
• Ama-Gargles womphimbo anqunywa amahlandla ama-3 ngosuku;
• fafaza, ngaphezu kwalokho okuqukethe ukuthambisa nezinongo zokuthambisa, zingasetshenziswa kaningi - kuya ezikhathini ezi-6;
• okokugcoba nejeli kusetshenziswa ngaphandle izikhathi 2 ngosuku;
• ukutheleleka esithweni sangasese kuphathwa ngama-suppositories, ukuwasebenzisa amaviki ama-1-3;
• iziqaqa zigcotshwa endaweni eyonakele futhi ziboshwe ngokuqinile usuku;
• i-antiseptic ngesimo samathebulethi inqunywa amahlandla ama-4 ngosuku, kokubili kubantu abadala nakubantwana abavela eminyakeni emi-5.

I-Gargling ngesisombululo se-chlorhexidine ichazwa izikhathi ezi-3 ngosuku.

Izithako kanye nejeli kusetshenziswa ngaphandle izikhathi ezi-2 ngosuku.

Ukutheleleka nge-Vaginal kuphathwa ngama-suppositories, ukuwasebenzisa amaviki ama-1-3.

Ukwakheka okuqinile (amaswidi, ama-lozenges) kudliwa ngemuva kokudla, akuhlafunwanga noma kugwinyiwe, kepha kuxazululwa kancane. Izindlela zokubulala zisetshenziselwa ukwelapha amathuluzi ezokwelapha (asulwa ngesipanji oswakanyiswe ku-antiseptic noma afakwe kuwo). Uma kunesidingo sokuphuza umuthi ngemithi eyinkimbinkimbi, umthamo unqunywa udokotela oya khona. Isibonelo, ku-urology (nge-urethritis noma irethroprostatitis), i-Chlorhexidine ifakwa ku-urethra ngokuhamba kwezinsuku eziyi-10.

Ngoshukela

Esikhathini sikashukela, i-chlorhexidine ingasetshenziswa kunoma yiluphi uhlobo. Usebenzisa amaswidi anongiwe, kudingeka uqiniseke ukuthi awanawo ushukela, kepha esikhundleni salawo.

Imiphumela emibi ye-chlorhexidine

Imiphumela emibi:

• komzimba
• dermatitis;
• ukulunywa
• i-tartar (enama-rinses omlomo avamile);
• ukulahlekelwa ukunambitheka (nge-gingivitis).

Umthelela ekhonweni lokulawula izindlela

Ukuba khona kwomuthi emzimbeni kubangela ukwephulwa kwemiphumela yokulawulwa kokudumba kwemithi.

Esikhathini sikashukela, i-chlorhexidine ingasetshenziswa kunoma yiluphi uhlobo.

Phakathi kwemiphumela emibi ye-chlorhexidine, ukulunywa kuhlukaniswa.

Ngama-rinses omlomo avame ngezixazululo ze-chlorhexidine, i-tartar kungenzeka.

Imiyalo ekhethekile

Ungavumeli isisombululo ukufinyelela ezindaweni ezivulekile nge:

• ukulimala kwengqondo ebuhlungu;
• ukulimala kwentambo yomgogodla;
• ukugcwala kwe-eardrum.

Ezinye izincomo:

• Izici ze-antibacterial zomuthi ziyathuthuka lapho zifudumele;
• lapho izinga lokushisa likhuphuka lifika ku-100 ° C, into esebenzayo ibola futhi ihlukaniswe ingxenye ethile;
• akufanele isetshenziswe kanyekanye ne-iodine namanye ama-antiseptics;
• uma lungena ezingxenyeni zehlo lamehlo noma emgodleni ongaphakathi onesifo sendlebe, kufanele ugezwe ngokuphelele ngamanzi;
• ungancomi ukusetshenziswa kwamafomu uketshezi ukuhlanza isikhumba ngemuva kweminyaka engama-30 kuya kwengu-40 ngenxa yobungozi bokweqa ngokweqile
• isixazululo asikwazi ukugwinywa (uma kungenzeka ukuthi kugxilwe ngengozi, kungcono ukuhlamba isisu ngamanzi amaningi);
• ama-suppositories awanconywa ukuthi asetshenziswe ngasikhathi sinye neViagra.

Lapho izinga lokushisa likhuphuka lifika ku-100 ° C, into esebenzayo ibola futhi ihlukaniswe ingxenye ethile.

I-Chlorhexidine akufanele isetshenziswe ngasikhathi sinye ne-iodine namanye ama-antiseptics.

Ama-suppositories awanconyelwe ukusetshenziswa ngasikhathi sinye neViagra.

Isabelo sezingane

Ebuntwaneni, i-chlorhexidine isetshenziswa ngokuqapha. I-lozenges ne-lozenges ayinqunyelwe ukuba ifike eminyakeni emi-3 ngenxa yobungozi bokungenwa ngokuzithandela (noma okunqunyiwe, ngemuva kokugaya ibe ngu-powder, kepha kusuka eminyakeni engu-5 ubudala). Izingane zinconywa izinhlobo ze-chlorhexidine ebhalwe "D" (isibonelo, amakhandlela Geksikon D).

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Umuthi kulezi zimo awunakwekwe uma ingekho imiphumela emibi. Ngezifo zomphimbo, abesifazane abakhulelwe banikezwa i-Lizobakt ephephile (i-France) ephephile, ekhiqizwa ngendlela ye-lozenges.

Ukweqisa

Amafomu aqinile, ukuze kugwenywe ukweqisa, kufanele athathwe ngokuya ngemiyalo enamathiselwe. Ukusetshenziswa isikhathi eside kwekhambi noma isifutho kubangela ukoma kolwelwesi lwama-mucous nesikhumba.

Ukuxhumana nezinye izidakamizwa

I-Chlorhexidine (amafutha, isixazululo) ayihambelani nensipho, i-alkali ne-anionic compounds:

• ama-saponins (amagwebu e-foil goscosides);
• ama-colloids (izixazululo ze-gelatinous);
• i-gum arabic (i-polysaccharide yemvelo, i-resinive resin);
• i-sodium lauryl sulfate (i-ejenti yokuhlanza esebenzayo);
• sodium carboxymethyl cellulose (isengezo sokudla esinamathelayo).

I-lozenges ne-lozenges ayinqunyelwe ukuba ifike eminyakeni emi-3 ngenxa yobungozi bokungenwa ngokuzithandela.

Izingane zinconywa izinhlobo ze-chlorhexidine ebhalwe "D" (isibonelo, amakhandlela Geksikon D).

Ngezifo zomphimbo, abesifazane abakhulelwe banikezwa i-antiseptic antiseptic Lizobakt (France) ephephile.

Ukusetshenziswa isikhathi eside kwekhambi noma isifutho kubangela ukoma kolwelwesi lwama-mucous nesikhumba.

Umuthi uyahambisana neqembu le-cationic:

• i-belzalkonium chloride (ukulondolozwa kanye ne-antiseptic);
• i-cetrimonium bromide (elondolo).

Ukuhambisana notshwala

Utshwala bukhulisa isenzo se-chlorhexidine.

Ama-Analog

Ama-anelegi omuthi ngokwegama lomhlaba wonke elingalungisiwe (igama lento esebenzayo):

• I-Chlorhexidine bigluconate;
• I-Chlorhexidine gluconate;
• Isibindi se-Chlorhexidine;
• Ahdez 3000.

Eminye imithi esekwe kule antiseptic:

• Amident, Tsiteal - izixazululo;
• Gibiscrab - amakhandlela;
• I-Heoticon, Katedzhel - ijeli;
• I-Plivasept - amafutha, isixazululo, isichibi.

I-Chlorhexidine (amafutha, isixazululo) ayihambelani nensipho.

Utshwala bukhulisa isenzo se-chlorhexidine.

I-analogue yesidakamizwa ngokwegama lomhlaba wonke elingashayi eceleni i-Ahdez 3000.

Imibandela yekhefu lekhemisi

I-OTC.

Ngingakwazi ukuthenga ngaphandle kadokotela

Ngaphandle kwesithako, imikhiqizo yentengo yento ehlanganisiwe iyathengiswa, engathengwa ezimungwini zePVC (200 ml) noma emacansini we-polyethylene canvas (1, 5, 25 no-50 l). Amaphilisi, okhilimu kanye nama-plasters nawo awanayo izidingo ezengeziwe. Kepha ngokuqokwa okuzimele, udinga ukufunda imiyalo.

Intengo

Intengo incike kumafomu nakubakhiqizi:

• Isixazululo esingu-100 ml emabhodleleni epulasitiki -12 rub .;
• fafaza i-100 ml - ama-ruble angama-23 .;
• Amatafula eSebidin ama-20 ama-pcs. - Ama-ruble ayi-150 .;
• Izibhebhe ezineleks Hexoral Tabs ama-20 ama-pcs. - Ama-ruble ayi-180 .;
• i-aerosol Hexoral (0,2% chlorhexidine) 40 ml - ama-ruble angama-370;
• fafaza u-Anti-Angin 25 ml nge-vial ngesifutho - ama-ruble angama-260 .;
• Ama-anti-Angin lozenges ama-24 ama-pcs. - Ama-ruble ayi-170 .;
• amaphilisi we-resorption u-Anti-Angin ama-20 ama-PC. -130 rub .;
• ijeli ene-lidocaine Katedzhel engu-12,5 g - ama-ruble ayi-165.
• I-Curasept liquid (Switzerland) 200 ml (0,05% chlorhexidine) - ama-ruble ayi-1310.

Izimo zokugcina zomuthi

Kunconywa ukugcina i-chlorhexidine endaweni eyomile futhi emnyama, ngamazinga okushisa angadluli ku-25 ° C.

Isikhathi sokuphelelwa yisikhathi

Impilo yeshelf iyakhonjiswa kwiphakheji. Isixazululo samanzi sigcinwa iminyaka emi-3. Amafomu asele yiminyaka emi-2, yile:

• ijeli yamazinyo;
• okhilimu namafutha okugcoba;
• ama-aerosols;
• i-lozenges;
• ama-suppositories;
• isakhi se-bactericidal.

Izisombululo ezenziwe ngomumo ekufakweni kwemboni kufanele zisetshenziswe kungakapheli isonto elilodwa ngemuva kokuvulwa.

Izixazululo ezilungiselelwe esibhedlela kufanele zidliwe kungakapheli amahora ayi-10 ngemuva kokulungiswa.

Umkhiqizi

Ezinye izinkampani zakwamanye amazwe ezikhiqiza izidakamizwa ne-chlorhexidine esetshenziswayo:

• UGlaxo Wellcome, ePoland (Ukulungiselela uSebidin);
• I-Famar Orleans, USA (Hexoral Spray);
• Nobelfarm ilach, Turkey (antiseptic Anzibel);
• IHerkel, iNetherlands (i-Drill lozenges, uswidi ka-Anti-Angin);
• I-AstraZeneca, UK (isixazululo);
• I-Curaprox, Switzerland (I-Curasept fluid fluid);
• IGIFRER BARBEZAT, eFrance (umuthi weChlorhexidine Giffer).

Izisombululo ezenziwe ngomumo nge-chlorhexidine kwiphakheji yangempela kufanele zisetshenziswe kungakapheli isonto elilodwa ngemuva kokuvula.

Abenzi bezindlu:

• I-Nizhpharm OJSC;
• I-LLC "iRosbio";
• I-Ergofarm LLC;
• I-CJSC Petrospirt.

Ukubuyekezwa

UMaria, oneminyaka engama-39, eMoscow

Ngaso sonke isikhathi nginesisombululo kwikhabethe lomuthi, ngiphatha yonke into - kusuka kumqubuko kanye nokuqaqanjelwa komzimba kuya ekuphumeni nasekuseni. Futhi njenge-ovis ye-antiseptic ngisebenzisa i-Clotrimazole (nayo i-chlorhexidine).

U-Ana, oneminyaka eyi-18, u-Omsk

Ama-lollipops amnandi, ngisebenzisa njalo ukuvikela umphimbo obuhlungu namakhaza.

UMikhail, oneminyaka engama-64, uPenza

Phambilini, ngaphendukela ku-iodine kuphela. Kepha ngemuva kokuhlinzwa maduze nje, odokotela batusa i-Chlorhexidine yokwelashwa kwe-suture. Kusetshenziswe kaningi kunezikhathi ezingama-2-3, umuthi usizile okuningi, futhi awushiyi izinsalela ezingutsheni (ngokungafani nama-greenbacks).