I-Orsoten umuthi onciphisa ukumuncwa kwamafutha emathunjini, ulawula inqubo yokudla kilojoule futhi ngokwemvelo ususe cishe ama-30% wamafutha omzimba emzimbeni. Ngakho-ke, umuthi usiza ukunciphisa isisindo somzimba womuntu.
Amakhandlela anqunywe njengengxenye yokwelapha okuyinkimbinkimbi. Ngaphambi kokusebenzisa umuthi, kuyadingeka ukuthi uyohlolwa izivivinyo zokwelashwa, uthintane nodokotela wakho futhi ufunde imiyalo yokuyisebenzisa ngokuningiliziwe.
I-ATX
A08AB01.
I-Orsoten umuthi onciphisa ukumuncwa kwamafutha emathunjini.
Khipha amafomu nokwakheka
Ifomu elihlanganiswe lomuthi linokwakheka okulandelayo:
- isakhi esisebenzayo i-orlistat;
- isithako esengeziwe yi-microcrystalline cellulose;
- umzimba we-capsule nesivalo - amanzi amsulwa, i-hypromellose, i-titanium dioxide (E171).
Izibhebhe ze-Gelatin zinombala ophuzi ophuzi noma umbala omhlophe omhlophe.
Okuqukethwe umuthi kuyinhlanganisela yama-microgranules, i-powder ne-agglomerates (kwezinye izimo).
Amaphilisi we-Oral ahanjiswa emakhemisi nasezindlini zezokwelapha kumagobolondo (ama-blima) ama-polymer aqinile.
Amacwecwe agcwele emabhulashini ama-pcs ayi-7 noma angama-21., Namagobolondo e-polymer wona atholakala ephepheni lekhadibhodi le-3, 6, 12 noma 1, 2, 4 ama-PC.
Isenzo se-Pharmacological
Umuthi uvimbela ama-enzyme aphule i-triglycerides, uthinta ukukhanyiswa kwesisu kanye namathumbu amancane, akha isibopho samakhemikhali phakathi kwe-orlistat kanye nesifunda sokuqongelela sokusula kwamathumbu namathumbu asesiswini.
Umuthi uvimbela ama-enzyme aphule ama-triglycerides, athinta ukukhanyiswa kwesisu kanye namathumbu amancane.
Ngenxa yalokhu, ama-enzyme alahlekelwa amandla okuguqula ama-triglycerides abe ngama-acid alula alula. Futhi amafutha angena emzimbeni ngokudla awangeni ezindongeni zesisu futhi angangeni egazini. Ngakho-ke, kukhona ukwehla kokudla kokudla kwekhalori, futhi isisindo somzimba sesiguli sincishisiwe.
Amafutha akhishwa emzimbeni kanye nesithako esisebenzayo ngesikhathi sokuhamba kwamathumbu. Okuqukethwe kwabo ezindlini zokugcwala kuyakhula ngaphakathi kwezinsuku eziyi-1-2 ngemuva kokuthatha amaphilisi.
Ochwepheshe bezokwelapha baphawula ukuthi ngokusetshenziswa isikhathi eside kwalo muthi, izinga le-cholesterol yamahhala lenziwa labajwayelekile.
I-Pharmacokinetics
Izinga lokufakwa kwengxenye esebenzayo lincane, ngakho-ke ngesikhathi sokwelashwa azikho izimpawu zokuqokelelwa kwalo kuyi-plasma yegazi.
Ngemuva kokuphathwa ngomlomo, isidakamizwa sixhumana ne-albhamuin namaprotheni, angama-cholesterol ayingozi.
Umuthi osebenzayo umanyelwa emgodini wokugaya ukudla futhi ucashunwa emathunjini (98%) nezinso (2%).
Ukuqedwa ngokuphelele kwenzeka ngezinsuku ezingama-3-5.
Izinkomba zokusetshenziswa
MP iyanconywa ukuthi isetshenziswe:
- ngokulashwa isikhathi eside kokukhuluphala, uma i-index mass body (BMI) ingu-30 kg / m² noma ngaphezulu;
- ukususa isisindo ngokweqile uma iBMI idlula ama-27 kg / m².
Ngesikhathi sokwelashwa, kufanele unamathele ekudleni.
Esimweni lapho ukukhuluphala ngokweqile kungabeki usongo empilweni nasempilweni yesiguli, lesi sidakamizwa asinqunyelwe.
Ngesikhathi sokulashwa, kufanele unamathele ekudleni lapho okuqukethwe okunamafutha ekudleni (amahora angama-24) kungafanele kudlule ama-30%.
Contraindication
Umuthi awukwazi ukusetshenziswa kwezinye izimo:
- isikhathi sokuzala noma sokukhishwa kwengane;
- iminyaka efinyelela eminyakeni eyi-18;
- ukungabekezelelani komuntu ngamunye noma i-hypersensitivity ezingxenyeni ezikhona ekwakhekeni komuthi;
- inqubo eguqulwe ngokomqondo yokuthunyelwa kwe-bile emathunjini amancane;
- ukwephulwa kokungena kwezakhi zamathumbu emathunjini (malabsorption syndrome).
Ungayithatha kanjani
Ngesikhathi sokudla okuyinhloko, kukhiqizwa ama-enzyme adingekayo womzimba. Umuthi unconywa ukuthi uphuzwe okwamanje kuphela noma kungakapheli ihora udlile.
I-capsule kufanele ithathwe ngenani elikhulu loketshezi, 1 pc. (120 mg) izikhathi ezi-3 ngosuku.
Uma imenyu ingenawo amafutha, i-MP ayikwazi ukusetshenziswa.
Isikhathi senkambo yokwelapha singeqi iminyaka emi-2. Ukudla okunconyiwe kwe-capsule izinyanga ezintathu.
Ukwanda komthamo akubangeli umphumela omuhle.
Ukwelashwa Ngokukhuluphala ku-Type 2 Diabetes
Umuthi ubekelwe ukwelashwa kweziguli ezinesifo sikashukela. Ukwelapha kuleli cala kwenziwa kanye nama-hypoglycemic agents. Ngaphezu kwalokho, iziguli ziyelulekwa ukuba zinamathele ekudleni nasendleleni yokuphila esebenzayo (ukuzivocavoca, ukuhamba nsuku zonke).
Imiphumela emibi
Amapheshana wesisu
Imiphumela emibi kakhulu ibonwa kakhulu emgudwini wesisu.
Lokhu kufaka phakathi:
- ukungakhululeki, izinhlungu esiswini;
- ukunqwabelana kwamagesi emathunjini;
- ukwanda kwesibalo sesifiso sokudiliza;
- ukungahambi kahle fecal;
- isifo sohudo
- ukhipha ngoketshezi olunamafutha;
- izihlalo okuxekethile.
Kufanele kukhunjulwe ukuthi ukubonakaliswa kwalezi zimpawu kuyisizathu sokudla ukudla okunamafutha noma okungekuhle. Ngakho-ke, ngesikhathi sokwelashwa kuyadingeka ukuqapha ikhwalithi yokudla futhi unamathele ekudleni ngenani eliphansi lamakhalori.
Ngasohlangothini lwe-metabolism
Iziguli ezinesifo sikashukela zingathola ukwehla kweglucose yegazi (ngaphansi kuka-3.5 mmol / L).
Isistimu yezinzwa ephakathi
Kusukela ohlangothini lwesistimu yezinzwa ephakathi, ikhanda, isiyezi, ukuqwasha nokukhathazeka okungazelelwe kungenzeka.
Kusuka ezinso nasegunjini lokuchama
Ezimweni ezingazodwa, ukuthuthukiswa kwezifo emgodini we-genitourinary ngenxa yokungena kwamagciwane we-pathogenic kuyabonakala.
Kusuka ohlelweni lokuphefumula
Imiphumela emibi engaba khona ifaka phakathi ukwanda kwezigameko zokuphefumula okungaphezulu nangaphansi.
Allergies
Phakathi kokusabela komzimba kuyaphawulwa:
- ukulunywa
- ukuqhuma
- i-urticaria;
- I-edema kaQuincke;
- i-bronchospasm;
- ukwethuka kwe-anaphylactic.
Phakathi kokunye ukubonakaliswa, inothi:
- ukuthuthukiswa kwesifo sendlebe nomphimbo;
- umkhuhlane
- isilonda esiyingozi sezinsini.
Imvamisa, izehlakalo ezingezinhle zithambile futhi zenzeka ezinyangeni ezi-3 zokuqala zokwelashwa. Ngemuva kwesikhathi esibekiwe, izimpawu ziqala ukuba buthaka.
Uma izinhlungu ezinkulu zibonwa, ubukhulu bawo abupheli ngenyanga eyi-1, ukusetshenziswa kwamaphilisi kufanele kuyekwe.
Imiyalo ekhethekile
Lapho uthatha amaphilisi, isiguli sinconywa ukuba sisebenzise amalungiselelo we-multivitamin ukuhlinzeka umzimba ngezinto ezidingekayo nokuvimbela ukuvela kwemiphumela emibi.
Uma ukwelashwa kungadali miphumela emihle kungakapheli amasonto ayi-12, ukusetshenziswa kwomuthi kumele kumiswe ukuze kuhlolwe udokotela.
Ngokwe-hypothyroidism, umuthi ocwazimulayo ubekwa ngokuqapha.
Ngokwe-hypothyroidism, umuthi ocwazimulayo ubekwa ngokuqapha.
Umthelela ekhonweni lokulawula izindlela
Ngokubonakaliswa okujwayelekile kwemiphumela emibi (isiyezi, isicanucanu), ukuzithiba kwezindlela kufanele kushiywe. Kwezinye izimo, ukusetshenziswa komuthi akusona isizathu sokwenqaba ukushayela imoto.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuthatha umuthi ngenkathi uzala ingane kungaholela ekuthuthukisweni kwe-pathologies esibelethweni. Ngesikhathi sokuqunjelwa - ekwehleni kwekhwalithi yobisi lwebele.
Ukuqokwa kwe-Orsoten ezinganeni
Umuthi lo usetshenziselwa ukwelapha iziguli ezingaphezulu kweminyaka eyi-18.
Sebenzisa ebudaleni
Umthamo uqokwa udokotela ohambayo ngesisekelo sezinkomba nezimpawu zomzimba ngamunye.
Ebudaleni, umthamo ukhethiwe ngokusetshenziselwa izinkomba zomuntu kanye nezimpawu zomzimba.
Ngomsebenzi wokuphazamiseka wezinso
Ukulungiswa kwedosi akudingeki.
Ngokungasebenzi kahle kwesibindi
Akukho shintsho.
Ukweqisa
Amacala we-overdose nokubonakaliswa kwemiphumela emibi engezekile abhalwe phansi. Kodwa-ke, uma umthamo ophakanyisiwe weqiwe, kuyadingeka ukubheka uchwepheshe amahora angama-24.
Ukuxhumana nezinye izidakamizwa
Inhlanganisela ayinconywa
Ama-multivitamini kufanele athathwe ihora eli-1 ngemuva kokuqeda i-Orsoten, ngoba ukusebenzisa kanyekanye i-MP kungaphazamisa ukumuncwa kwamavithamini ancibilikayo.
Ama-multivitamini kufanele athathwe ihora eli-1 ngemuva kokuqeda i-Orsoten.
Ukusetshenziswa okuhlanganiswe kwalesi sidakamizwa okubuzwa ngaso ngama-anticoagulants kuholela ekwandeni kwe-INR, ukwehla kwezinga le-prothrombin kanye noshintsho kuma-indices egazi le-coagulogram.
Ngokunakekela
Umuthi usebenzisana kakhulu nePravastanin, ngenxa yokuthi ukusetshenziswa kanyekanye kwezidakamizwa kuholela ekwandeni kokugcotshwa kwemithi enciphisa i-lipid ku-plasma yegazi.
Ukusabela okubucayi emuva kuyabonakala lapho amakhompiyutha asetshenziswa ndawonye ne-cyclosporin noma ne-amiodarone. Ngakho-ke, izivivinyo zomtholampilo ezijwayelekile ziyadingeka ngesikhathi sokwelashwa.
Ngokuncipha kwesisindo somzimba womzimba kwiziguli ezinezifo ze-endocrine, i-metabolism iyathuthuka, ngakho-ke, kunconyelwa ukulungisa umthamo wemithi enciphisa ushukela.
Ama-Analog
Phakathi kokufana kwesidakamizwa okucutshungulwayo, okulandelayo kuyahlukaniswa:
- Allie
- I-Reduxin;
- I-Xenical
- I-Xenalten
- Uhlu.
Ngaphezu kwalokho, lo muthi ukhishwa ngaphansi kwegama elifanayo ngokufakwa kwamagama athi Light and Slim.
Ngokungafani neminye imithi, i-Reduxine ihlose ukunciphisa isisindo isikhathi eside (0.5-1 kg ngeviki). Ngakho-ke, kaningi iziguli zikuthola kungcono ukuthatha ezinye izidakamizwa ezichazwe ngenhla.
Imibandela yekhefu lekhemisi
Umuthi umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kunamacala okuthengiswa kwalo muthi ngaphandle kokuqokwa ngudokotela. Kodwa-ke, ukuzelapha kungadala ushintsho olubi emzimbeni.
Intengo ye-Orsoten
Izindleko ezimaphakathi zesidakamizwa (i-120 mg) eRussia:
- Ama-ruble angama-700 ngamakhompiyutha angama-21;
- I-2500 yamaphilisi angama-84 ebhokisini.
Ukusetshenziswa kanyekanye kwe-Orsoten nePravastanin kuholela ekhuphukeni kwezinga lokuhlushwa le-lipid-lowing ejenti ku-plasma yegazi.
Izimo zokugcina zomuthi i-Orsoten
Ngemuva kokuthenga, umuthi kufanele ubekwe kwikhabethe noma kwenye indawo emnyama. Ukushisa okunconyiwe kwesitoreji - + 25 ° ะก.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Ukubuyekezwa mayelana ne-Orsoten
Odokotela
U-Olga, owondlayo, oneminyaka engu-46, uNorilsk
Iziguli zikhononda ngemiphumela emibi ngesikhathi sokwelashwa: izihlalo ezihlala njalo, ukuphuma kwamafutha, iphunga elingathandeki. Kodwa-ke, lapho sinquma umuthi, sikhuluma ngokuningiliziwe ngokuthi ungadla kanjani, iyiphi indlela yokuphila okufanele unamathele kuyo. Ukusetshenziswa kwamafutha amakhulu lapho usebenzisa amaphilisi kuholela ekubonakaleni kwalezi zimpawu.
UValery, okondlayo, oneminyaka engu-53, uSamara
Umuthi omuhle wokususa amakhilogremu angeziwe. Kepha ngesikhathi sokwelashwa, ukudla nokuzivocavoca akufanele kunganakwa, ngaphandle kwalokho imiphumela emibi izovela.
Ukulahlekelwa iziguli ezisindayo
UMarina, oneminyaka engama-31 ubudala, eVoskresensk
Ngiqale ukuthatha lo muthi ngenyanga edlule. Ngalesi sikhathi, balahle ama-7 kg ngaphezulu. Ekuqaleni kokwelashwa, imiphumela emibi yenzeka ngendlela yokuchama kaningi nokudonswa kwamafutha. Manje lezi zimo azivamile.
U-Olga, oneminyaka engama-29 ubudala, eSt
Bengilokhu ngithatha amakhebuli amaviki ama-3, kepha angibonanga umphumela omuhle. Futhi kunemiphumela emibi eminingi: ubuthakathaka, isiyezi, ukukhipha iphunga elingathandeki. Ngenza udokotela nodokotela.
UKristina, oneminyaka engama-34, eMoscow
Umuthi omuhle kakhulu - odokotela bayakuvuma futhi bancoma abangane bami. Ngiqale ukuyisebenzisa ezinsukwini ezingama-21 ezedlule, kukhona ushintsho olubonakalayo - ngokwesisindo nangevolumu.
