I-Lescol Forte: imiyalo kanye nokufana kwezidakamizwa

Nge-cholesterol ephakeme, kubalulekile ukukhetha indlela efanele yokwelashwa futhi usondele ngokufanele ekukhetheni kwezidakamizwa. Umuthi kufanele usebenze, ungabizi, ube nenani elincane lokuphendula okungathandeki.

Enye yezidakamizwa ezidumile ezidambisa ama-lipid ngokweqile yiLeskol Forte. Ungayithenga kunoma iyiphi ikhemisi, wethula incwadi kadokotela. Imithi enjalo ayilungele ukuzelapha, ngoba uma ukhetha umthamo ongalungile kanye nohlobo lokwelashwa, ingadala ukulimala okukhulu emzimbeni.

Ngaphambi kokusebenzisa umuthi, kubalulekile ukubonana nodokotela ozokunikeza umthamo ngqo, ugxile esimweni sesiguli nasemlandweni wezokwelapha. Ngokuvamile, i-Lescol Forte inezibuyekezo ezinhle kakhulu ezigulini nodokotela.

Ngabe usebenza kanjani umuthi?

Into esebenzayo yesidakamizwa ekhonjiswe esithombeni yi-fluvastatin. Lesi yisisebenzeli esinciphisa i-lipid, esingokwama-inhibitors we-HMG-CoAreductases futhi sifakiwe eqenjini lama-statins. Ukuqanjwa futhi kufaka phakathi i-titanium dioxide, i-cellulose, i-potassium hydrogen carbonate, i-iron oxide, i-magnesium stearate.

Ungathenga umuthi esitolo sokhemisi noma esikhethekile lapho wethula incwadi kadokotela. Imithi ikhiqizwa ngohlobo lwamacwecwe e-convex ngombala ophuzi, intengo yawo ama-ruble angama-2600 nangaphezulu.

Umgomo wokwelashwa ngamathebulethi ukucindezela ukukhiqizwa kwe-cholesterol kanye nokunciphisa inani layo esibindini. Ngenxa yalokhu, iphesenti le-lipid eyingozi egazini legazi lesiguli liyancishiswa.

1. Uma uthatha njalo i-Leskol Forte, ukugcwala kwe-LDL kuncishiswa ngamaphesenti angama-35, inani eliphelele le-cholesterol - ngamaphesenti angama-23, ne-HDL ngamaphesenti ayi-10-15.
2. Njengoba ukubonile kubonisile, ezigulini ezinezifo zenhliziyo ezithatha amaphilisi iminyaka emibili, ukucwaswa kwe-coronary atherosclerosis kwaqapheleka.
3. Ezigulini ngesikhathi sokwelashwa, ubungozi bokuthola isifo sohlelo lwezinhliziyo, ukufakwa kwe-myocardial, noma unhlangothi kuncishiswa kakhulu.
4. Imiphumela efanayo ibonwa ezinganeni eziphathwa ngamaphilisi.

Imiyalo yokusebenzisa

Ukuthola imininingwane enemininingwane ngeLeskol Fort, kufanele ufunde imiyalo yokusebenzisa umuthi. Umuthi uthathwa kanye ngosuku nganoma yisiphi isikhathi, noma ngabe sidliwe kanjani. Ithebhulethi ligwinywa ligcwele futhi ligezwe ngenani elikhulu loketshezi.

Umphumela wesenzo somuthi awubonwa kungakapheli amasonto amane kamuva, ngenkathi umphumela wokwelapha uphikelela isikhathi eside.

Ngaphambi kokuqala ukwelashwa, isiguli kufanele silandele indlela yokudla ejwayelekile ye-hypocholesterol, nayo eqhubeka kuyo yonke inkambo.

Ekuqaleni, kunconywa ukuthatha iphilisi elilodwa lama-80 mg. Uma lesi sifo sincane, kwanele ukusebenzisa i-20 mg ngosuku, lapho kutholakala khona amaphilisi. Umthamo ukhethwa udokotela, kucatshangelwa izici zomzimba nezinkomba ze-lipids eziyingozi. Lapho kukhona isifo senhliziyo ngemuva kokuhlinzwa, kusetshenziswa iphilisi elilodwa ngosuku.

• Isidakamizwa i-LescolForte sinconyelwe ukuthi singazihlanganisi nezinye izidakamizwa kuleli qembu. Okwamanje, ukubamba okwengeziwe kwe-fibrate, i-nicotinic acid ne-cholestyramine kuvunyelwe ngokuya ngomthamo.
• Izingane nentsha engaphezu kweminyaka eyisishiyagalolunye ubudala ingalashwa ngamathebhulethi ngokulingana nabantu abadala, kodwa ngaphambi kwalokho, kubalulekile ukuba udle ngendlela efanele nangokudla okwelapha izinyanga eziyisithupha.
• Njengoba umuthi udlulwa ikakhulukazi ngokubamba iqhaza kwesibindi, iziguli ezinenkinga yezinso zingasebenzi ukuguqula umthamo.
• Ukuthatha umuthi kuyaphulwa uma kunesifo sezinso esisebenzayo, ukwanda okuqhubekayo kwenani lama-serum transaminases wemvelaphi engaziwa.

Ngokusho kwezifundo, amaphilisi kanye namaphilisi kuyasebenza kunoma iyiphi iminyaka. Lokhu kufakazelwa nokubuyekezwa okuningi okuhle. Kepha khumbula ukuthi umuthi unemiphumela emibi eminingi okudingeka uyazi ngaphambi kwesikhathi.

Gcina imishanguzo ekushiseni okungaphansi kwama-25 degrees, kude nelanga eliqondile nezingane. Impilo yeshelufu lamathebulethi yiminyaka emibili.

Ngubani okhonjelwe ukwelashwa

I-Leskol Forte isetshenziselwa i-hypercholesterolemia, i-dyslipidemia, isifo sokuqina kwemithambo yegazi, kanye nokuvimbela izifo zenhliziyo. Ezinganeni ezineminyaka engaphezu kwengu-9 ubudala, ukwelashwa kuboniswa lapho kunesici sofuzo esenzakalweni sokulimala kwe-lipid metabolism.

Ukuthatha umuthi kuyaphulwa uma kukhona i-pathology yesibindi nezinso, ukusabela komzimba ezintweni ezisebenzayo kanye nezakhi zomuthi. Awukwazi ukwenza ukwelashwa ngesikhathi sokukhulelwa nokuncelisa.

Awekho amacala e-overdose ahlonziwe. Noma kunjalo, amaphilisi angaba nazo zonke izinhlobo zemiphumela emibi ngendlela:

1. I-Vasculitis ezimweni ezingavamile kakhulu;
2. I-Thrombocytopenia;
3. Ubuhlungu bekhanda, i-parasthesia, i-hypesthesia, okunye ukuphazamiseka kohlelo lwezinzwa;
4. I-Hepatitis ezimweni ezihlukile, ukuphazamiseka kwe-dyspeptic;
5. Ukuphazamiseka kwesikhumba;
6. I-Myalgia, i-myopathy, i-rhabdomyolysis;
7. Ukwanda okuphindwe kashlanu kwe-creatine phosphokinase, ukwanda okuphindwe kathathu kwe-transmiasis.

Ukunakekelwa okukhethekile kumele kuthathwe ngabantu abasebenzisa kabi utshwala, kanye nesifo esikhona kwesibindi. Kubandakanya akudingekile ukufeza ukwelashwa kwe-rhabdomyolysis, izifo zemisipha esingelapheki, ukukhonjwa kwamacala angaphambilini okuphendula okungalungile komzimba kuma-statins.

Ngaphambi kokuthi uqale ukuthatha imishanguzo, kufanele uhlole isimo sesibindi. Ngemuva kwamasonto amabili, kunikezwa ukuhlolwa kwegazi lokulawula. Uma umsebenzi we-AST ne-ALT unyuka ngaphezu kokuphindwe kathathu, kufanele wenqabe ukuthatha umuthi. Lapho isiguli sine-pathology yegilo, ukusebenza kokulimala kwesibindi nezinso, ukudakwa, kuhlaziywa okwengeziwe ukuze kuguqulwe inani le-CPK.

Ngokunikezwa iqiniso lokuthi i-fluvastatin esebenzayo yezinto ayihlangani nezinye izidakamizwa, ingathathwa ngokuhlangana namanye amaphilisi. Kepha uma usebenzisa izidakamizwa ezithile, kufanele unake ezinye izici.

Ikakhulu, ethatha iRimfapicin ngasikhathi sinye, iLeskol Forte inciphisa ukusebenza komzimba.

Futhi, kwesinye isikhathi i-bioavailability incishiswa ngamaphesenti angama-50, kulokhu, udokotela ulungisa umthamo okhethiwe noma ukhetha uhlobo oluthile lokwelashwa.

Ngesikhathi sokwelashwa nge-Omeprazole ne-Ranitidine, esetshenziselwa ukuphazamisa ipheshana emathunjini, kunalokho, ukumonyelwa kwe-fluvastatin kukhushulwa, okwandisa umphumela wamathebulethi emzimbeni.

Ukufana kwezidakamizwa

Umuthi i-Leskol Forte unezifaniso eziningi, okwamanje kunamatafula anjalo angaphezu kwangama-70, into esebenza ngayo yi-fluvastatin.

Eshibhile kakhulu yi-Astin, Atorvastatin-Teva neVasilip, izindleko zazo zingama-ruble angama-220-750. Futhi ekhemisi ungathola ama-statins Atoris, Torvakard, Livazo, anenani lentengo elifanayo lama-ruble ayi-1,500.

I-Krestor, i-Rosart, i-Liprimar idluliselwa emithini ebiza kakhulu, amaphilisi anjalo azodla ama-ruble ayi-2000 kuya ku-2000.

Uhlobo luni lwama-statins akhona

Amanani amakhulu okuqina ahlanganisa iRosuvastatin ne-Atorvastatin, iLovastatin, iSimvastatin, iFluvastatin, i-Pravastatin inamandla alinganiselayo.

Zonke lezi zidakamizwa ziyakwazi ukwenza ngendlela efanayo, kepha umzimba womuntu uhlala usabela kangcono ohlotsheni oluthile. Ngakho-ke, odokotela bavame ukuncoma ukuzama ama-statin ambalwa nokukhetha eyodwa ephumelela kakhudlwana.

Ezinye izidakamizwa kuleli qembu zihlangana nezinye izidakamizwa. Ngakho-ke, isibonelo, i-Atorvastatin, i-Pravastatin ne-Simvastatin ayikwazi ukusetshenziswa ngemuva kokuphuza ujusi we grapefruit, lokhu kungaholela emiphumeleni eyingozi. Iqiniso ukuthi ujusi wamawolintshi ukhulisa ukugcwala kwama-statins egazini.

Okwamanje, kunezizukulwane ezine zemithi ye-cholesterol ephezulu.

• Izidakamizwa zesizukulwane sokuqala zihlanganisa i-Simgal, Zovotin, Lipostat, Cardiostatin, Rovacor. Amathebhulethi anjalo anomphumela ophansi we-lipid, okungukuthi, anciphisa ukuhlanganiswa kwama-lipids ayingozi futhi avimbele ukunqwabelana kwawo emithanjeni yegazi. Inani le-triglycerides nalo liyancipha futhi ukugcwala kwe-cholesterol enenzuzo kuyakhuphuka. Izidakamizwa zisetshenziswa ekwelapheni i-coronary atherossteosis.
• ILeskol Forte ingeyama-2nd ezizukulwaneni ezingama-2, ivuselela ukukhiqizwa kwama-lipoprotein aphezulu kwabantu, okuholela ekugcineni ekunciphiseni ekuqoqweni kwama-lipids nama-triglycerides ayingozi. Umuthi uvame ukubekelwa i-hypercholesterolemia, futhi ungaphakanyiswa njenge-prophylactic yezifo zohlelo lwethambo nenhliziyo.
• Izidakamizwa zesizukulwane sesithathu zisetshenziswa uma ukudla okwelashwa nokuvivinya umzimba kungasizi. Lawa ngamaLiprimar, Tulip, Anvistat, Lipobay, Torvakard, Atomaks, Atorvaks. Kubandakanya le mithi kubhekwa njengesinyathelo esihle sokuvimbela isifo senhliziyo, isifo sikashukela, izifo zenhliziyo. Imiphumela yokwelapha ibonwa ngemuva kwamasonto amabili.
• Ezisebenza kakhulu nezingabizi kakhulu emzimbeni ziyi-statins zesizukulwane se-4. Banesibalo esincane se-contraindication nemiphumela emibi, ngakho-ke amaphilisi angasetshenziswa kubandakanya ukwelashwa kwezingane. Kulokhu, umthamo mncane, futhi imiphumela ibonakala ezinsukwini ezimbalwa. Lokhu kufaka phakathi izidakamizwa ezinjenge-Acorta, Tevastor, Roxer, Krestor, Mertenir, Livazo.

Udokotela ohlanganyelayo kuphela onganquma ukuthi yimaphi amaphilisi okufanelekile ukusebenzisa ngemuva kokufunda umlando wezokwelapha nemiphumela yokuxilonga. Ukuze isebenze, ama-statin kufanele athathwe njalo. Kodwa kubalulekile ukuqapha isimo sesiguli nsuku zonke ukuze kuvikelwe ukukhula kwemiphumela engathandeki, ngoba izidakamizwa kuleli qembu zinenqwaba yemiphumela emibi.

Izimo zichaziwe kuvidiyo ekulesi sihloko.