I-Bagomet Plus iyi-ejenti ephumelelayo ye-hypoglycemic ehlose ukusetshenziswa kwangaphakathi komlomo. Kusetshenziselwa ukwelapha isifo sikashukela sohlobo lwe-2, kukuvumela ukuthi umise ngokushesha izimpawu eziyingozi zalolu sifo.
Igama Lezwe elingafanele
Metformin hydrochloride + glibenclamide
IBagomet Plus iyatholakala kwifomu lethebhulethi.
I-ATX
NoA10BD02
I-Metformin ihlanganiswe ne-sulfonamides.
Khipha amafomu nokwakheka
Kuyatholakala ngesimo sethebhulethi. Amathebulethi anokwakheka okulandelayo kanye nomthamo:
- metformin hydrochloride 500 mg + glibenclamide - 2 5 mg;
- metformin hydrochloride 500 mg + glibenclamide - 5 mg.
Izibhebhe zifakwe kumhlophe ngefilimu. Izinto ezisizayo ezifakwe ekwakhiweni zifaka i-lactose monohydrate, i-magnesium, i-sodium, isitashi.
Isenzo se-Pharmacological
Lesi sidakamizwa sinomphumela obizwa ngokuthi yi-hypoglycemic ngenxa yokuhlanganiswa kwe-metformin ne-glibenclamide. I-Metformin ingeyama-biguanides. Kwandisa ukuzwela kwezicubu zomzimba ezithinta imiphumela ye-insulin, ngaleyo ndlela kunciphisa glucose wegazi. Iqinisa izinga le-cholesterol embi egazini.
I-Glibenclamide (i-sulfonylurea derivative) ibambezela ukumuncwa kwama-carbohydrate ngepheshana lesisu. Inika amandla ukukhiqizwa okusheshayo kwamaseli we-pancreatic β-seli ngamaseli abo.
I-Pharmacokinetics
IBagomet Plus ibonakala ngezinga eliphakeme le-bioavailability engaba ngu-60%. Umuthi uthathwa kalula yi-metabolism. Isigamu sempilo singamahora ayi-6. Ukuqoqwa okukhulu kwezinto ezisebenzayo kutholakala ngemuva kwamahora we-1.5-2 kusukela ngesikhathi sokuthatha amaphilisi. Izakhi ezisebenzayo zomuthi zidlulwa ngokwengxenye nge-bile ngosizo lwezinto ezinobuthi bezinso.
Izikhombisi ze-Bolomet Plus
Kunqunyelwe iziguli ezinenhlobo 2 yesifo sikashukela:
- ukusebenza okunganele kokudla nokwelashwa kokudla;
- ukungabikho kwemiphumela yokwelashwa lapho usebenzisa i-glibenclamide yodwa noma i-metformin;
- ngezinga elizinzile le-glycemic elisebenziseka ukuqashwa kwezokwelapha;
- nokukhuluphala, ukuthuthukisa ukumelana nesizinda se-mellitus engavikeleki nge-insulin.
IBagomet Plus ichazwe uma kungasebenzi kahle ukwelashwa kanye nokuzivocavoca.
Ivame ukusetshenziswa kakhulu ngokuhlanganiswa nezinye izidakamizwa ekwelapheni okuyinkimbinkimbi kweziguli ezinesifo sikashukela sohlobo 2 njengesici esisizayo.
Contraindication
Kuyenqatshelwe ngokuphelele ukusebenzisa umuthi ezimweni ezinjalo:
- thayipha i-1 isifo sikashukela (ifomu lokuncika kwe-insulin);
- ukwephulwa kokujikeleza kwegazi ebuchosheni, kuqhubeke ngesimo esibi.
- ukuthambekela kokuthuthukisa i-lactic acidosis;
- izinga le-creatinine ngaphezulu kwe-135 mol / l;
- uphuzo oludakayo;
- ukwehluleka kwenhliziyo, ukuhanjiswa kwe-myocardial;
- izinhlobo ezinzima ze-renal kanye ne-hepatic pathologies;
- isifo sikashukela sikashukela;
- ukubonakaliswa kwe-hypoglycemia, ikoma lesifo sikashukela kanye ne-precoma;
- umlando we-acidosis;
- isigaba seminyaka yesiguli esidala kuneminyaka engama-60;
- izifo ezenzeka ngendlela ebushelelezi noma engamahlalakhona ene-hypcomia izicubu ezithathelwanayo, izifo;
- hypersensitivity noma ukungabekezelelani ngakunye kwezinto ezisebenzayo.
Umuthi iBagomet Plus unqatshelwe ngokuphelele ukusebenzisa uhlobo lwesifo sikashukela.
Le ejenti ye-hypoglycemic icutshaniswe nokulimala okulimaza kakhulu okutholakale ekungeneleleni kwamuva kokuhlinzwa ngesikhathi sokwelashwa kwe-hypocaloric yokudla. Ngokunakekelwa okukhethekile, umuthi usetshenziselwa ukwelapha iziguli ezingasebenzi kahle i-thyroid, umkhuhlane, izilonda ze-pathological ze-adrenal cortex, pituitary hypofunction.
Ungayithatha kanjani iBagomet Plus?
Yakhelwe ukusetshenziswa kwasendlini. Amaphilisi weBagomet Plus, ngokuya ngemiyalo, kufanele aphuzwe aphelele, ngaphandle kokuhlafuna, ngamanzi amaningi ahlanzekile. Thatha umuthi ngokudla. Umthamo ophelele unqunywa udokotela uqobo, kucatshangelwa amazinga kashukela egazini kanye nezimpawu zecala lomtholampilo.
Ngokuya ngohlelo olujwayelekile, inkambo yokwelapha eneBagomet Plus iqala ngethebhulethi elilodwa, elithathwa isikhathi esingu-1 ngosuku. Uma kungekho ukusabela okungahambi kahle, umthamo ungakhuphuka kancane kancane ngemuva kwamaviki ama-2 elashwa.
Ukuthatha isidakamizwa iBagomet Plus kuqala ngethebhulethi elilodwa kanye ngosuku, ngemuva kwamaviki ama-2 umthamo ungandiswa.
Uma kukhonjisiwe, udokotela angakhulisa umthamo wansuku zonke kumatafula ama-2, athathwe izikhathi ezi-2 usuku lonke. Ukuze uguqule umthamo, izifundo ziqhutshwa njalo okuhloswe ngazo ukuthola amazinga kashukela egazini.
Umthamo omkhulu wansuku zonke akufanele wedlule amaphilisi ama-4. Ngokuya kumthamo obekiwe, kunconywa ukubheka izikhathi zokungena ukuze kulondolozwe ukugcwala okuphelele kwezinto ezisebenzayo egazini. Uma kuthathwe i-1 ithebhulethi, khona-ke kungcono ukuyiphuza ngesikhathi sasekuseni.
Ngomthamo omkhulu, wonke umthamo wezidakamizwa uhlukaniswe izingxenye ezintathu, uthathe amaphilisi ekuseni, ntambama kanye namahora kusihlwa.
Lapho kukhona ukuphazamiseka kwe-metabolic, umuthi ubekelwa ngemithamo emincane, usengezelela nezinye izidakamizwa ukuze uthole imiphumela emihle yokwelashwa.
Imiphumela emibi yeBagomet Plus
Inkambo yokwelashwa ngeBagomet Plus ingavusa ukuthuthukiswa kwale miphumela engemihle elandelayo:
- isicanucanu kanye nezikhathi zokuhlanza;
- Ubuhlungu bendawo esiswini;
- ukwephulwa kokusebenza kokusebenza kwamapheshana emathunjini;
- i-anemia
- i-lactic acidosis;
- umuzwa wokunambitheka kwensimbi emgodini womlomo;
- i-hypoglycemia;
- i-hepatitis;
- ukubonakaliswa kokungafani komzimba;
- ukulunywa kwesikhumba nemivimbo, njenge-urticaria;
- i-erythema;
- ukuntuleka kwaphakade kwesifiso sokudla;
- umsebenzi we-hepatic okhubazekile;
- ukukhathala;
- ubuthakathaka obujwayelekile, i-malaise;
- ukuhlaselwa ngesiyezi.
Imiphumela emibi ebhalwe phansi ibonakaliswa kubantu asebekhulile, ukwephula irejimeni yokudla efaneleyo, isiguli sinokuphambana.
Uma kwenzeka imiphumela emibi kakhulu, kufanele ufune usizo lodokotela ngenhloso yokulungisa umthamo noma ukubuyisela umuthi nge-analogue efanelekile.
Umthelela ekhonweni lokulawula izindlela
Ithuluzi lingaba nomthelela ovimbayo ohlelweni lwezinzwa oluphakathi kanye nesivinini sokuphendula kwengqondo.
Ngakho-ke, ngesikhathi senkambo yokwelapha, kuzoba ngcono ukwenqaba ukushayela izimoto nezinqubo eziyinkimbinkimbi.
Imiyalo ekhethekile
Abantu abanesifo sikashukela abathatha lo muthi badinga kakhulu ukuqapha ushukela wegazi.
Izilinganiso kufanele zithathwe ekuseni ngesisu esingenalutho, bese kuthi emva kokudla.
Ngesikhathi sokulashwa, kubalulekile ukulandela indlela odlalelwa ngayo udokotela futhi udle njalo. Ngaphandle kwalokho, izingozi zokuthuthukisa i-hypoglycemia ziyanda. Umthamo ulungiswa ohlangothini lokuncipha lapho uguqula indlela odla ngayo, ukucindezelwa okwandayo, ukusebenza ngokweqile kwengqondo noma ngokomzimba.
Ngesikhathi sokulashwa ngeBagomet Plus, kubaluleke kakhulu ukulandela ukudla okudliwe ngudokotela futhi udle njalo.
Isiguli kufanele siqaphe ngokucophelela izinguquko esimweni sayo. Lapho usebenzisa umuthi, i-acidosis ingakhula, ihambisane nomcanucanu, ukuphefumula nokuqaqamba kwethonya. Ezimweni ezinjalo, funa ukwelashwa ngokushesha.
Uma ngesikhathi sokulashwa isiguli sikhombise i-pathologies yesimo esithathelwanayo, uhlelo lwe-urinary, lokhu kufanele futhi kwaziswe udokotela wakho.
Lapho uqhuba ama-x-ray, usebenzisa ama-ejenti aphambanayo aphethwe ngaphakathi, umuthi kufanele uchithe izinsuku ezimbili.
Inkambo yokwelashwa iqala emuva kwezinsuku ezimbalwa ngemuva kwezinqubo zokuxilonga, ukungenelela kokuhlinzwa.
Sebenzisa ebudaleni
Musa ukuqoka abantu abaneminyaka yobudala eseqile (ngaphezulu kweminyaka engama-60-65), okungenxa yokuphakama okukhulu kwe-acidosis kanye nokuvela kokunye ukusabela okungahambi kahle. Okokuqala, lo mthetho usebenza kubantu asebekhulile abasebenza kanzima.
Isabelo sezingane
Ngenxa yokuntuleka kolwazi olwanele mayelana nomphumela emzimbeni wezingane, lesi sidakamizwa asinconywa ekwelashweni kweziguli ezingaphansi kweminyaka yobuningi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ayisetshenziselwa ukuphatha abesifazane abakhulelwe. Abesifazane abaphethe ingane futhi bahlushwa uhlobo oluzimele lwe-insulin yesifo sikashukela bayanconywa ukuthi basebenzise iBagomet nge-insulin.
Ngesikhathi sokukhulelwa, kunconywa ukufaka iBagomet Plus nge-insulin.
Ungasisebenzisi lesi sidakamizwa lapho uncelisa ibele ngenxa yokuntuleka kolwazi oluqondile mayelana nekhono lezinto ezisebenzayo ukungena ngaphakathi ebisini lwebele. Uma kunobufakazi, ingane idluliselwa kokuphakelayo okufakelwa.
Isicelo sokusebenza kokulimala kwezinso
Ukusetshenziswa kwomuthi kuyaphikiswa ezigulini ezinenkinga yokuhluleka kwe-renal kanye nokulimala kwezintso. Ungancomi ukwelashwa kwezidakamizwa kokuphelelwa ngamanzi emzimbeni, ngezimo zokushaqeka nezinqubo ezinzima zesimo esithathelwanayo esingathinta kabi umsebenzi wezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Odokotela abaluniki lo muthi ezigulini ezinenkinga yokuhluleka kwesibindi noma abanezinkinga ezinzima ngemisebenzi yezitho.
Ukweqisa
Ukweqa umthamo onconyiwe kungavusa ukubonakaliswa okunjalo:
- isicanucanu kanye nezikhathi zokuhlanza;
- ukuqaqamba kwemisipha;
- ukuhlaselwa kwesiyezi;
- isifo sezinhlungu senziwe esiswini;
- izimpawu ezijwayelekile ze-asthenic;
- isifo sohudo
- ukulahlekelwa ukwazi.
I-overdose yeBagomet Plus ingadala uhudo.
Ngokubonakaliswa okunjalo kliniki, isiguli sidinga usizo oluphuthumayo lwezokwelapha. Ngaphandle kwalokho, inqubo ye-pathological iyaqhubeka futhi ihambisana nokuqwashiswa okungasebenzi kahle, ukuvimbela umsebenzi wokuphefumula, ukuwa kukhathaza, futhi nokufa kwesiguli.
Ukwelashwa ngokweqile kwenziwa ngaphansi kokulashwa esibhedlela ngaphansi kokuqashwa ngokweqile kwezokwelapha.
Iziguli zihlushwa i-hemodialysis, okuyinkambo yokwesekwa okubonisa izimpawu.
Ukuxhumana nezinye izidakamizwa
Ama-cyclophosphamides, ama-anticoagulants, izidakamizwa ezingezona ezingama-antiidalidal anti-inflammatory, izidakamizwa ze-antimycotic, ama-anabolic steroid, ama-inhibitors we-ACE, i-Fenfluramine, iChloramphenicol, i-Acarbose inegalelo ekwandiseni umphumela we-hypoglycemic.
Ukusetshenziswa kwama-barbiturates, ama-glucocorticosteroids, ama-hormone okuvimbela inzalo, ama-diuretics, izidakamizwa ze-antiepileptic, kunalokho, kwenza buthaka umphumela we-Bagomet Plus, unciphise ukusebenza kwekhosi.
Ukuhambisana notshwala
Lesi sidakamizwa se-hypoglycemic asihambelani notshwala.
Ngakho-ke, phakathi kokusebenzisa iBagomet Plus kunconywa kakhulu ukwenqaba ukuphuza utshwala nemithi, kubandakanya ne-ethyl alcohol.
Ama-Analog
Amathuluzi afanayo afaka: i-Zukronorm, Siofor, Tefor, Glycomet, Insufor, Glemaz, Diamerid.
Imibandela yekhefu lekhemisi
Lesi sidakamizwa singathengwa kuphela lapho kwethulwa incwadi kadokotela efanelekile.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Ngaphandle kwemithi evela kudokotela, lesi sidakamizwa asikadedelwa.
Intengo yeBagomet Plus
Izindleko ezijwayelekile ziyahlukahluka kusuka kuma-ruble angama-212 kuya kwangama-350.
Izimo zokugcina zomuthi
Umuthi unconyelwa ukuba ugcinwe endaweni eyomile, emnyama, epholile, engafinyeleleki ezinganeni ezincane.
IBagomet Plus idinga ukugcinwa endaweni eyomile, emnyama, epholile, isikhathi esingekho ngaphezulu kweminyaka emi-3.
Isikhathi sokuphelelwa yisikhathi
Akudluli iminyaka engu-3, ukusetshenziswa okuthe xaxa kubekiwe.
Umkhiqizi
Inkampani "Kimika Montpelfer S.A.", Argentina.
Ukubuyekezwa mayelana neBagomet Plus
UValeria Lanovskaya, oneminyaka engama-34, eMoscow
Sekuphele iminyaka eminingana ngilashwa ngeBagomet Plus. Umuthi usimamisa ngokushesha ushukela wegazi, ubekezelelwa kahle futhi unezindleko ezingabizi.
U-Andrey Pechenegsky, oneminyaka engama-42 ubudala, idolobha laseKiev
Nginendlela yokuzimela yesifo sikashukela engizimele. Ngazama imali eningi, kepha udokotela weluleka ukusetshenziswa kweBagomet Plus. Wanelisekile ngomphumela wesidakamizwa, futhi okubaluleke kakhulu - ukungabi bikho kwesidingo semijovo ejwayelekile.
Inna Kolesnikova, iminyaka engama-57, idolobha laseKharkov
Ukusetshenziswa kweBagomet Plus kukuvumela ukuthi wehlise ngokushesha amazinga kashukela, uthuthuke kahle futhi ubuyele empilweni ejwayelekile. Umuthi ubekezelelwa kahle. Ngiyithatha ngethamo elinconyiwe, ngidla kahle, ngakho angikaze ngihlangane nemiphumela emibi.
