I-Moflaxia umuthi wokulwa namagciwane owenziwa eqenjini lamakhemikhali le-fluoroquinolones. Umphumela obizwa ngokuthi yi-antimicrobial of Moflaxia uvumela ukusetshenziswa kwalesi sidakamizwa ekwelapheni izifo eziningi ezithathelwanayo.
Lesi sidakamizwa sisebenza kakhulu, kepha into esebenzayo ye-Moflaxia inobuthi, ngakho-ke, umuthi unezindlela eziningi zokuphikisana futhi ungadala imiphumela emibi. Umuthi kufanele uphuzwe ekunconyweni kukadokotela, kwimithamo ekhonjiswe kwimiyalo.
Igama Lezwe elingafanele
INN yesidakamizwa yi-moxifloxacin.
I-ATX
Kuhlukano lwe-ATX lwamazwe omhlaba, umuthi unekhodi J01MA14.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo sethebulethi. Ithebhulethi elilodwa liqukethe okungenani i-400 mg yesithako esiyisisekelo esisebenzayo - moxifloxacin hydrochloride. Ngaphezu kwalokho, ukwakheka komuthi kufaka i-macrogol, i-titanium dioxide, i-hypromellose, udayi. Izibhebhe zinobume be-capsic biconvex. Zimbozwe ngenhlanganisela yefilimu epinki. Amaphilisi we-Moflaxia afakwa emabhulashini ama-5, 7 noma ama-10 ama-PC. Amabhola agcwele emasakeni amakhadibhodi. Umuthi osendaweni yesisombululo sokuphathwa kwe-intramuscular and intravenous awutholakali.
Umuthi uyatholakala ngesimo sethebulethi.
Isenzo se-Pharmacological
Into esebenzayo ye-Moflaxia ingeyeqembu le-fluoroquinolones, ngakho-ke inomphumela ophikisiwe wezinto ezinhlobonhlobo ezinhlobonhlobo zezinto eziphilayo ezingama-pathogenic. Isenzo somuthi kungenxa yokuthi kungenzeka ukuthi kuvimbele into esebenzayo yokulungiselela ama-topoisomerases angama-bacterium ezinhlobo 2 no-4, ngenxa yokuthi ukusabela kwe-DNA biosynthesis kwenzeka emangqamuzaneni e-pathogenic microorganisms, okuholela ekufeni kwamagciwane.
Into esebenzayo ye-Moflaxia ithinta zombili ama-gram-positive kanye ne-gram-negative microorganisms. Ngaphezu kwalokho, umuthi usebenza ngempumelelo ezimelana nezinhlobo ze-microflora ye-pathogenic.
I-Pharmacokinetics
Ngemuva kokuthatha umuthi, into yawo esebenzayo idonswa ngokushesha. Ngaphezu kwalokho, i-bioavailability yomuthi ifinyelela kuma-91%. Ngokudliwa nsuku zonke kwe-Moflaxia izinsuku eziyi-10, okuqukethwe ngokulingana komuthi kutholakala kungakapheli izinsuku ezintathu. Iqoqo eliphezulu lomuthi ku-plasma lifinyelelwa cishe amahora angama-1.5-2. Ukuthatha umuthi ngokudla kwandisa isikhathi lapho okuqukethwe okuphelele kwezakhi ezisebenzayo zomuthi ku-plasma yegazi kutholakala.
Ukuthatha umuthi ngokudla kwandisa isikhathi lapho okuqukethwe okuphelele kwezakhi ezisebenzayo zomuthi osegazini kutholakala.
Into esebenzayo ye-Moflaxia isengcupheni yokuqalwa kwe-biotransformation ngokwakhiwa kwama-metabolites ama-2, kufaka phakathi i-sulfo compounds, engasebenzi, nama-glucuronides, anomthelela wemithi. Kodwa-ke, ama-metabolites awafani nge-biotransformed yi-cytochrome system. Imikhiqizo yokubola iyadedelwa kamuva kumchamo nezindunduma.
Isikhathi sokumbiwa kwezingxenye ezisebenzayo zeMoflaxia cishe amahora ayi-12.
Izinkomba zokusetshenziswa
Lo muthi ungabekelwa izifo ezahlukahlukene zemvelo ezithathelwanayo, ezihambisana nokuvuvukala okunzima. Kunconywa ukusebenzisa umuthi kuphela uma isiguli siqinisekisa ubukhona be-microflora obucayiwe ku-Moflaxia. Izinkomba zokusebenzisa umuthi zingaba yi-sinusitis esibuhlungu.
Umuthi unconywa ukuthi usetshenziswe ekwandiseni ifomu le-bronchitis elingamahlalakhona. Ukuqokwa kukaMohlaxia kuvunyelwe ekwelapheni izifo zesikhumba zesifo esithathelwanayo, kuqhubeke ngaphandle kwezimpawu zokukhuluma zokuvuvukala. Ukusetshenziswa kwe-Moflaxia ngezinhloso zokwelapha kunesizathu ekwelapheni amaphaphu atholakala emphakathini, kufaka phakathi lawo okubangelwa izingqinamba ezingamelana nemithi elwa namagciwane.
Njengengxenye yokwelashwa okuphelele kwezidakamizwa, lesi sidakamizwa sinconywa ukuba sinqunyelwe i-sinusitis. I-Moflaxia elinganiselwe ingasetjenziselwa izifo eziyinkimbinkimbi zesikhumba. Ngalo muthi, ungalapha unyawo lwesifo sikashukela, oluyinkimbinkimbi ngokufakwa kwegciwane lesibili.
Izinkomba zokusetshenziswa kwalesi sidakamizwa ama-abscesses ama-intra-isisu kanye nezifo eziyinkimbinkimbi zokulimazeka kwangaphakathi esiswini. Ukusetshenziswa kwe-Moflaxia kunesizathu ekwelapheni izifo zokuvuvukala zohlelo lokuzala lowesifazane. Ngaphezu kwalokho, umuthi ungasetshenziselwa i-prostatitis yesimo esithathelwanayo.
Contraindication
Ukusetshenziswa kwe-Moflaxia kunqatshelwe nge-hypersensitivity ezingxenyeni ezisebenzayo zomuthi. Ngaphezu kwalokho, lesi sidakamizwa asinqunyelwe iziguli ezinomlando wama-tendon pathologies aqhamuke ngesikhathi sokwelashwa ngemithi elwa ne-quinolone antibacterial.
Umuthi awanconywa kubantu abaphethwe inhliziyo ngokungaphatheki kahle.
Contraindication ukusetshenziswa kwomuthi ukuphazamiseka kwe-electrolyte, kuhambisane nokuvela kwe-hypokalemia, okungekhona ukuthi kulungiswe. Ukuxhumana okusetshenziselwa umuthi kungukuphazamiseka kwesigqi kanye ne-bradycardia. Akunconywa umuthi futhi uma isiguli sinezimpawu zokuhluleka kwenhliziyo okuhlala njalo.
Ngokunakekela
Ngokuqapha ngokweqile, lo muthi unqunyelwe ezigulini ezine-CNS pathologies, ezihambisana nokubonakala kokuthakathi. Ukuqashwa okukhethekile kwesimo sesiguli ngabasebenzi bezokwelapha kuyadingeka uma isiguli sinokuphazamiseka kwengqondo.
Ngaphezu kwalokho, lo muthi kufanele usetshenziswe ngokuqapha ekwelapheni iziguli ezinesifo senhliziyo kanye nokuba nomlando wokuboshwa kwenhliziyo. Ukwelashwa kwe-Moflaxia kweziguli ezine-cirrhosis kufanele kwenziwe ngaphansi kokuqashwa kukachwepheshe. Kulesi sigaba seziguli, ubungozi bokuqhamuka nemiphumela emibi nokwandisa inkambo yesimo se-pathological ekhona buyakhula.
Ngokuqapha ngokweqile, lo muthi ubekelwe iziguli ezine-CNS pathology.
Ungamthatha kanjani uMoflaxia
Lo muthi wenzelwe ukusetshenziswa kwangaphakathi. Ekwelapheni izifo ezithathelwanayo ezibangelwa amagciwane abhekene nezenzo zento esebenzayo i-Moflaxia, lo muthi kufanele uphuzwe ngokomthamo we-400 mg (i-1 i-tablet) kanye ngosuku. Ithebhulethi kufanele igwinye ngaphandle kokuhlafuna, futhi uqiniseke ukuyiphuza ngamanzi. Ukuthola umphumela wokwelapha ku-pathologies etheleleka kakhulu, ukuthatha umuthi ngezinsuku ezingama-5-7 kwanele. Ngokutheleleka okuyinkimbinkimbi kwesikhumba kanye nesisu esiswini, inkambo yokwelashwa ingaba ezinsukwini eziyi-14 kuye kwezingu-21.
Ukuthatha umuthi wesifo sikashukela
Iziguli ezinesifo sikashukela i-mellitus zinikezwa umthamo we-400 mg ngosuku, kepha kudingeka ukuthi kuqashelwe ngokucophelela amazinga kashukela egazini.
Iziguli ezinesifo sikashukela, umuthi unqunywe kumthamo we-400 mg ngosuku.
Imiphumela emibi ye-Moflaxia
Ekwelashweni kweziguli ezineMoflaxia, ukubukeka kwemiphumela emibi evela ezinhlotsheni nasezinhlotsheni ezahlukahlukene akuvamile ukubonwa. Inkambo ende yokwelashwa kwezidakamizwa ingadala izimo zokuvela kokukhululeka okuvela fungal.
Amapheshana wesisu
Ukwemukelwa kwe-Moflaxia kunomthelela oqondile emgodini wokugaya ukudla futhi kubangele ushintsho kumaticrofilora wamathumbu, okwandisa ubungozi bemiphumela emibi ohlelweni lokugaya ukudla. Ngokwemininingwane yemitholampilo, iziguli eziningi kakhulu ngemuva kokuthatha uMoxlaxia zinezikhalazo zokucanuzelelwa kwenhliziyo, ukuphazamiseka kwesisu nobuhlungu besisu. Ngokuvamisile nge-Moflaxia therapy, ukwehla kwesifiso sokudla kuyabonakala. Ngaphezu kwalokho, ukuthuthukiswa kwe-flatulence kanye ne-dyspepsia kungenzeka. Ezimweni ezingandile, i-stomatitis, i-grositis erosayo, i-dysphagia, ne-colitis ivela ngesikhathi sokwelashwa nomuthi.
Izitho zeHematopoietic
Ngokwelashwa okuhlala isikhathi eside, ushintsho lwe-pathological ekuhlushweni kwe-thromboplastin ku-plasma yegazi kungenzeka. Ngaphezu kwalokho, ezigulini ezinokwelashwa kwe-Moflaxia, i-leukopenia ne-anemia kungenzeka. I-Thrombocytopenia kanye nokwanda kwamazinga e-prothrombin kungabhekwa.
Isistimu yezinzwa ephakathi
Ekwelapheni kukaMoflaxia, ukubonakala kokuphazamiseka kwengqondo okuncane, okuvezwa ukwanda kokuphazamiseka kwengqondo nokukhathazeka, kungenzeka. Ezinye iziguli zibhekana nokudangala kanye nokuzikhandla ngokomzwelo. Ama-hallucinations nokuphazamiseka kokulala kungenzeka. Nge-Moflaxia therapy, isiyezi nekhanda kungenzeka. Ukuphazamiseka okungenzeka embonweni wokunambitheka nephunga, i-dysesthesia, i-paresthesia ne-peripheral polyneuropathy.
Kusuka ohlelweni lomchamo
Imiphumela emibi evela ekusetshenzisweni kweMoflaxia kohlelo lwezitho zofuzo ayivelakancane. Kungahle kube nezimpawu zokusebenza kwe-renal ephazamisekile. Ukwehluleka kwangempela kungenzeka.
Kusuka ohlelweni lokuphefumula
Kuyaqabukela ekwelashweni kwezifo nge-Moflaxia, i-dyspnea kanye nokuhlasela kwesifuba somoya kungenzeka.
Engxenyeni yesikhumba nezicubu ezingaphansi
Ezimweni ezingazodwa, ukuthuthukiswa kwe-necrosis enobuthi kuyabonakala.
Engxenyeni ye-metabolism kanye nokudla okunempilo
Ngokuphikisana nesizinda sokuthatha i-Moflaxia, i-hyperlipidemia, i-hyperuricemia ne-hypoglycemia kungenzeka.
Kusuka ohlelweni lwezinhliziyo
Lapho usebenzisa iMoflaxia, ukuhlaselwa nge-tachycardia, gxuma ekucindezelweni kwegazi kanye nasekufeni okubangelwa ukwephula uhlelo lwenhliziyo kungenzeka.
Uma usebenzisa iMoflaxia, kungahlaselwa i-tachycardia kanye nokugxuma ekucindezelweni kwegazi.
Kusuka ezicutshini zemisipha
Ngokuphikisana nesizinda sokuthatha umuthi, ukuvela kwe-myalgia ne-arthralgia kungenzeka. Kwezinye iziguli, kuye kukhuphuke ithoni yemisipha kanye nemisipha. Ukuqhuma kwe-Tendon nokukhula kwamathambo akuvamile ukubonwa.
Allergies
Ekwelapheni i-Moflaxia, kungavela ukungezwani komzimba, kuboniswe njengokuqhuma kwesikhumba, ukulunywa kanye ne-urticaria. Ezimweni ezingavamile, i-angioedema ne-anaphylaxis kungenzeka.
Umthelela ekhonweni lokulawula izindlela
Lapho uphathwa ngeMohlaxia, kufanele wenqabe ukushayela imoto futhi ulawule ezinye izindlela eziyinkimbinkimbi.
Lapho uphathwa ngeMohlaxia, kufanele wenqabe ukushayela imoto.
Imiyalo ekhethekile
Ezigulini ezihlushwa yizifo zohlelo lokuthinta kwenhliziyo, ukusetshenziswa kwe-Moflaxia kudinga ukunakekelwa okukhethekile.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusetshenziswa kwe-Moflaxia kwabesifazane ngesikhathi sokukhulelwa nokuqunjelwa akunconywa.
Ukunquma uMoflaxia ezinganeni
Akunconyelwe ukusebenzisa umuthi ekwelapheni izingane nentsha engaphansi kweminyaka engu-18.
Akunconyelwe ukusebenzisa umuthi ekwelapheni izingane nentsha engaphansi kweminyaka engu-18.
Sebenzisa ebudaleni
Ezigulini esezikhulile, ushintsho kumthamo womuthi awudingekile.
Isicelo sokusebenza kokulimala kwezinso
Umsebenzi wokulimala wezinso awukona ukweqa ukwelashwa kwe-Moflaxia.
Sebenzisa umsebenzi wesibindi okhubazekile
Ngomsebenzi wesibindi okhubazekile kanye nokuba khona kokuhluleka kwesibindi, i-Moflaxia ingasetshenziswa ukwelapha izifo, kepha iziguli ezinama-pathologies anjalo zidinga ukubhekwa okukhethekile ngabasebenzi bezokwelapha.
Ngokungasebenzi kahle kwesibindi kanye nokuba khona kokuhluleka kwesibindi, i-Moflaxia ingasetshenziswa ukwelapha izifo.
Ukweqiwa kwe-Moflaxia
Uma usebenzisa umthamo omningi kakhulu, isiguli singaba ne-hypokalemia. Lapho kuvela izimpawu zokweqisa, isiguli sikhonjiswa ukwelashwa okubonakalayo.
Ukuxhumana nezinye izidakamizwa
Ngokusebenzisa kanyekanye kweMoflaxia eneWarfarin, ukuphazamiseka kwegazi kwegazi akubonwa. Ukusetshenziswa kanyekanye kwe-Moflaxia ngama-antidepressants ama-tricyclic, ama-antipsychotic, ama-antiarrhythmics nama-antihistamines akunconyiwe. Akunconywa ukuhlanganisa ukusetshenziswa kwe-Moflaxia namanye ama-antibiotic. Ukusetshenziswa ngasikhathi sinye kwe-Moflaxia ngama-antacid kusiza ukunciphisa ukusebenza kwe-antibiotic. Ikhabhoni esebenzayo futhi yehlisa ukusebenza kwe-antibiotic.
Akunconywa ukuhlanganisa ukusetshenziswa kwe-Moflaxia namanye ama-antibiotic.
Ukuhambisana notshwala
Lapho uthola ukwelashwa ngama-anti-antibiotic neMoglaxia, kufanele wenqabe ukuphuza utshwala.
Ama-Analog
Kunezidakamizwa ezimbalwa ezingasebenza njengendawo ye-Moflaxia, kufaka phakathi:
- I-Avelox.
- UMaxiflox.
- Moxin.
- I-Moxystar.
- I-Heinemos.
- I-Rotomox.
- I-Plevilox.
I-Avelox ingenye yokufanekisa kweMoflaxia.
Imibandela yekhefu lekhemisi
Umuthi utholakala kwezentengiso emakhemisi.
Ngingakwazi ukuthenga ngaphandle kadokotela
I-Moflaxia itholakala ngaphezulu kwekhawuntara.
Intengo ye-Moflaxia
Izindleko kumakhemisi zisuka kuma-ruble angama-300 kuye kwangama-340.
Izimo zokugcina zomuthi
I-Moflaxia kufanele igcinwe ku + 25 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshalofu yesidakamizwa yiminyaka emi-2.
Umkhiqizi
Lesi sidakamizwa senziwa yinkampani yezokwelapha yaseSlovenia i-KRKA.
Ukubuyekezwa kwe-Moflaxia
U-Irina, oneminyaka engama-32, uChelyabinsk
Ngisebenzisa i-Moflaxia ngama-exacerbations we-bronchitis. Lesi sifo senzeka ngesimo sami esingamahlalakhona futhi njalo ezinyangeni ezingama-2-3 sikhonjiswa izimpawu ezinzima. Ngisebenzisa i-Moflaxia izinsuku ezingama-2-3 futhi zonke izimpawu zisheshe zingene. Umuthi awuqedi ngokushesha ukuqeda lesi sifo, kodwa futhi awungibangeli imiphumela emibi. Ngihlela ukuqhubeka ngisebenzisa lo muthi.
UMaxim, oneminyaka engama-34, eMoscow
Cishe unyaka owedlule, kwana imvula futhi lapho efika ekhaya wayolala, engamomile ngokuphelele izinwele zakhe. Ekuseni ngizwe ingcindezi endaweni yeso nekhanda elinzima. Umuzwa wawungabekezeleleki, ngakho-ke ngokushesha ngaya kudokotela owathola ukuthi une-sinusitis eyingozi. Udokotela unqume uMoflaxia. Lesi sidakamizwa sisetshenziswe amaviki ama-2. Ngizwe ngcono ngosuku lwesibili, kepha nginqume ukuthatha isifundo ngize ngiyogcina, ngesaba izinkinga. Umuthi unikeza umphumela omuhle.
UKristina, oneminyaka engama-24, uSochi
Cishe ngonyaka owedlule wabamba umkhuhlane. Ekuqaleni, naphezu komkhuhlane, angizange nginake, kepha isimo sabe sesiqala ukuwohloka, ngakho-ke kwadingeka ngishayele i-ambulensi. Isibhedlela siveze inyumoniya. Ngokunconywa ngudokotela, waqala ukuthatha uMoflaxia.Ngemuva kokuqala umuthi, ngathola isicanucanu. Umuthi awenqabanga ukusithatha futhi ngemuva kwezinsuku ezimbalwa ngazizwa ngingcono. Ngathola ukwelashwa, okwathatha izinsuku eziyi-14, futhi ngiyaneliseka ngomphumela.
U-Igor, oneminyaka engama-47 ubudala, eSt
Nginenkinga yesifo sikashukela futhi yize ngilandela ngokucophelela ukudla futhi ngilawula ushukela, kwaqhamuka isilonda esivela emlenzeni wami, esanda ngokushesha ngosayizi futhi sasiqinisa. Njengoba kudalwe ngudokotela, wasebenzisa uMoflaxia njengengxenye yokwelapha okuyinkimbinkimbi. Ithuluzi lisize kakhulu. Isilonda saphela ukugcwala izinsuku eziningi futhi saqala ukwelashwa. Ngisebenzise i-antibiotic izinsuku eziyi-14. Akukhulunywa nganoma iyiphi imiphumela emibi.
