I-Actovegin - umuthi osiza ukuqinisa izinqubo ze-metabolic kwezicubu nemithambo yegazi, uvuselela inqubo yokuvuselela umzimba.
Igama Lezwe elingafanele
Akukona.
Igama lokuhweba yi-Actovegin®. NgesiLatin - Actovegin.
Ama-Ampoules anoketshezi olucacile noma olunombala omncane ophuzi.
I-ATX
I-B06AB (Eminye imikhiqizo yegazi)
Khipha amafomu nokwakheka
Ama-Ampoules anoketshezi olucacile noma olunombala omncane ophuzi.
Isithako esisebenzayo: i-hemoderivative encishisiwe, 40 mg / ml.
Kukhiqizwa yi-dialysis, ukuhlukaniswa kwe-membrane kanye nokuhlukaniswa kwezinhlayiya zegazi zezilwane ezisencane, ezinikezwa ubisi kuphela.
Ingxenye eyengeziwe: amanzi wokujova.
Ingakhiqizwa yizinkampani zemithi iTakeda Austria GmbH (Austria) noma iTakeda Pharmaceuticals LLC (RF). Ipakwe ku-2 ml, 5 noma 10 ml kuma-ampoule angenangilazi angenawo umbala ama-5 ama-pcs. ekufakweni okwenziwe ngopulasitiki okwenziwe ngeplastiki. Amaseli we-1, 2 noma ama-5 we-contour cell emabhokisini amakhadibhodi.
Umuthi ungoweqembu lama-antihypoxants.
Kwiphakethe ngalinye lamakhadibhodi kufanele kube nesitika esiyindilinga esinombhalo we-holographic nokulawulwa kokuvula kokuqala.
Isenzo se-Pharmacological
Kungokweqembu lama-antihypoxants. Ngaso leso sikhathi kunezinhlobo ezintathu zemiphumela:
- i-neuroprotective (ivimbela ukufa kwamangqamuzana obuchopho - ama-neurons - ngenxa yemiphumela emibi yezinqubo zangaphakathi ezingafuneki noma amathonya angaphandle);
- i-metabolic (ikhuthaza ukuhlanganiswa kwe-adenosine triphosphate (ATP) futhi inyusa amandla amaseli);
- i-microcirculatory (ukuthutha okuthuthukile kokusakazeka kwezinto eziphilayo ezicutshini nasezitsheni zomzimba).
Isiza ukuthuthukisa i-sorption kanye nokucubungula i-oksijini noshukela.
Kuphikisana nokwakheka kwezinqubo ze-apoptotic ezicasulwe yi-beta-amyloid (Aβ25-35). Iguqula ukuhamba kwengqondo ye-kappa B (NF-kB), okuyisikhuthazo esiyisihluthulelo ngesikhathi senqubo yokuvuvukala enkabeni yezinzwa nezinsimbi zezitho zomzimba kanye ne-apoptosis.
Inomphumela osebenzayo ku-microcirculation nokugeleza kwegazi kuma-capillaries, kunciphisa indawo ye-pericapillary kanye nengcindezelo ye-diastolic. Kuyafakazelwa ukuthi ukusebenza komuthi kubonwa ngemuva kwemizuzu engama-30, futhi umphumela omkhulu ngamahora ama-3 emva kokuphathwa.
I-Actovegin inomphumela osebenzayo wokugeleza kwegazi nokugeleza kwegazi kuma-capillaries.
I-Pharmacokinetics
Njengoba umuthi unezakhi zomzimba osuvele ukhona emzimbeni, izakhiwo zawo zamakhemikhali ngokwamapharamitha welebhu ngeke zifundwe.
Okunqunyelwe
I-Actovegin 40 ifakiwe kumarejimeni wokwelashwa anzima:
- ukuphazamiseka kwengqondo kwe-etiologies ehlukahlukene;
- ukungasebenzi kahle kwemisipha yengozi kanye nezingozi ze-cerebrovascular;
- i-angiopathy yengozi;
- isifo sikashukela se-neuropathy;
- ukuvuselelwa kwezicubu (ukuhlukunyezwa, ukuhlinzwa, izilonda ezi-venous zamaphethelo aphansi, njll.);
- imiphumela yokwelashwa ngemisebe.
Ngaphezu kwalokho, ngale fomu yemithamo, i-grositis e-erosive, izilonda ezingapheli zesisu kanye ne-duodenum ziyelashwa.
Contraindication
Akunconywa ngokuhlaselwa ngokweqile kwezakhi zomuthi, ukwehluleka kwenhliziyo ukubola, i-edema ohlelweni lwe-bronchopulmonary, oliguria, anuria kanye nezinqubo zokuhlangana emzimbeni.
Ngokunakekela
Lapho kukhona i-hyperchloremia ne-hypernatremia, ebuntwaneni.
Ungayithatha kanjani i-Actovegin 40
Isikhathi, imithamo kanye nama-regimens okwelashwa kunqunywa ngokusekelwe ezimweni zenqubo ye-pathological. Kunqunywa ngawodwana. Inqunywe ngaphakathi kwethambo, ngaphakathi nangaphakathi.
Ekwelapheni izilonda zesifo se-metabolic and vascular, emazingeni okuqala okwelashwa, i-10-20 ml ye-iv noma i-iv ilimala nsuku zonke. Ngemuva kwalokho, ngokuya ngerejimeni yokwelashwa, i-5 ml iv noma i-IM nge-infusion ebambezelekile.
Ku-ischemic stroke esiteji esibuhlungu, kusetshenziswa imithi.
Esikhathini sohlangothi lwe-ischemic esigabeni esibi, ama-infusions ayenziwa. Kulokhu, umuthi (10-50 ml) ungezwa ku-200-300 ml wenhlanganisela ye-isotonic (5% ushukela noma isisombululo se-sodium chloride). Emva kwalokhu, uhlobo lokwelashwa lushintshwa ukuze kuthathwe umuthi wethebhulethi umuthi.
Ukwelashwa kwezimo ezibangelwa ukuphazamiseka kwemithambo yengqondo, lesi sidakamizwa sinqunywe i-iv noma iv (20-30 ml yesidakamizwa ihlanganiswe no-200 ml wokwakheka kwe-isotonic).
Ukuqeda izimpawu zesifo sikashukela se-polyneuropathy, i-50 ml ye-iv iyafakwa. Ngemuva kwalokho imiphumela yokwelapha ishintshela ekusebenziseni i-Actovegin kumathebulethi.
Ngokuphathwa kwe / m, kufika ku-5 ml kusetshenzisiwe. Faka kancane.
Ukuthatha umuthi wesifo sikashukela
Kubhekiselwa kwimithi ebamba iqhaza ku-metabolism. Ngakho-ke, kuyimpoqo ekwelashweni okuyinkimbinkimbi kwesifo sikashukela.
Umuthi uyadingeka ekwelashweni okuyinkimbinkimbi kwesifo sikashukela.
Imiphumela emibi
Kubekezelelwa kahle. Ezimweni ezingavamile, imiphumela emibi ingavela.
Kusuka ohlelweni lwe-musculoskeletal
I-Myalgia (kuyaqabukela).
Kusuka emasosheni omzimba
Ukuvela kwe-allergic ngesimo sokubonakaliswa komtholampilo komkhuhlane wezidakamizwa noma ukushaqeka kwe-anaphylactic.
Engxenyeni yesikhumba
Ukuvuvukala, ukuqubuka, noma ubomvu.
Allergies
Ukuba khona kwesiphetho sokubonakaliswa komzimba kufanele kubikwe kudokotela.
Umphumela wecala lomuthi ungaba ukungezwani komzimba.
Imiyalo ekhethekile
Ngenxa yengozi yokusabela kwe-anaphylactic ngesikhathi sokusetshenziswa kokuqala, ukuhlolwa kwe-hypersensitivity kwalo muthi kufanele kwenziwe ngaphambi kokuphathwa.
Kuma-batches ahlukene, umuthi ungaba namandla ahlukile wombala. Kepha lokhu akukuthinti ukubekezelela isidakamizwa nomsebenzi waso.
I-ampoules evulekile ayigcini. Kufanele zisetshenziswe ngokushesha.
Ukuhambisana notshwala
Lapho uphuza utshwala awulahlekelwa yimpahla yokwelapha.
Umthelela ekhonweni lokulawula izindlela
Ayikho idatha etholakalayo.
Lapho uphuza utshwala awulahlekelwa yimpahla yokwelapha.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Umthelela ongemuhle esimweni sikamama noma se-fetus awuzange ubonwe.
Ukuqokwa kwe-Actovegin izingane ezingama-40
Inikezwe izinsana nezimpawu ze-hypoxia. Ngaphezu kwalokho, umuthi ubekelwe izingane ezizalwe futhi zathola ukulimala kobuchopho.
Sebenzisa ebudaleni
Kusetshenziswa ekwelapheni nasekuvinjelweni kwe-hypoxic ne-ischemic ukuphazamiseka kwezitho nezicubu ezigulini ezihlobene nobudala.
Ukweqisa
Azange kube namacala okweqisa kwe-Actovegin.
Kusetshenziswa ekwelapheni nasekuvinjelweni kwe-hypoxic ne-ischemic ukuphazamiseka kwezitho nezicubu ezigulini ezihlobene nobudala.
Kunethuba lokubonakaliswa okwengeziwe kwemiphumela emibi.
Ukuxhumana nezinye izidakamizwa
Ayikho imiphumela emibi evela ekuxhumaneni kwezidakamizwa etholakele.
Ihambisana nezindlela zokwelapha ezisetshenziselwa ukwelashwa okuyinkimbinkimbi kwesifo sohlangothi lwe-ischemic (ngokwesibonelo, neMildronate).
Ngaphezu kwalokho, isetshenziswa kabanzi ekuhlanganiseni ama-regimens nezidakamizwa ezisetshenziselwa ukuqeda ukungasebenzi kahle kwe-venous and placental, ekwelapheni i-thrombosis (ngokwesibonelo, ne-Curantil).
Inhlanganisela edinga ukuqashelwa
Ukuhlanganiswa ne-ACE inhibitors (i-Enalapril, iLisinopril, i-Captopril, njll.), Kanye namalungiselelo we-potassium, kudinga ukuqaphela.
Ama-Analog
Izikhala ze-Actovegin yilezi:
- I-Vero-Trimetazidine;
- I-Curantyl-25;
- I-Cortexin;
- I-Cerebrolysin, njll.
I-Curantil-25 iyi-analogue ye-Actovegin.
Imibandela yekhefu lekhemisi
Ngokusebenzisa umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Amakhemikhali amaningi e-inthanethi alungele ukuthengisa ngaphandle kwencwadi kadokotela.
Inani Actovegin 40
Izindleko ezijwayelekile zincike kumanani we-ampoules nenombolo yazo kwiphakheji. Ngakho-ke, isibonelo, eRussia, intengo ye-Actovegin (umjovo wama-40 mg / ml ampoules we-5 ml 5 pcs.) Iyahlukahluka kusuka kuma-ruble angama-580 kuya kwangama-700.
E-Ukraine, iphakethe elifanayo libiza cishe i-310-370 UAH.
Izindleko ezimaphakathi zomuthi zincike kumthamo we-ampoules nenombolo yazo kwiphakheji.
Izimo zokugcina zomuthi
Endaweni evikelwe ukukhanya kwelanga ekushiseni okufika ku-25 ° C. Fihla ezinganeni.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-3 kusukela ngosuku lokukhiqizwa.
Umkhiqizi
Nycomed Austria GmbH, Austria.
Iphakethe / okhipha ukulawulwa kwekhwalithi: I-Takeda Pharmaceuticals LLC (Russia).
Ukubuyekezwa kodokotela neziguli ku-Actovegin 40
Imibono yodokotela neziguli maqondana nokusetshenziswa, ukusebenza nokuphepha ayifani.
UVasilieva E.V., udokotela wezifo zemizwa, uKrasnodar
I-Actovegin cishe ayinayo imiphumela emibi futhi ibekezelelwa kahle. Ingasetshenziswa kokubili ku-monotherapy nakuhlobo olunzima lokwelashwa. Kukhethwe i-pathologies yesistimu yemithambo yethambo kanye nokwehluleka kwe-metabolic. Ngincoma iningi leziguli zami.
UMarina, oneminyaka engama-24, uKursk
Banikeze imijovo kanye namaconsi ngesikhathi sokukhulelwa ukuze kuzinze ukuhamba kwegazi ku-placenta. Awukho umphumela ongemuhle. Ngemuva kokwelashwa, ukuphuma kwegazi kubuyele kwesejwayelekile, futhi ukukhathala nesiyezi kwanyamalala kanye nokukhubazeka. Ngeluleka bonke abesifazane abakhulelwe.
UNefedov I.B., oneminyaka engama-47, u-Oryol
Naphezu kweqiniso lokuthi lesi sidakamizwa sivinjelwe i-FDA (UMnyango Wezempilo kanye Nezinsizakalo Zabantu BaseMelika), isetshenziswa kabanzi eRussia nasemazweni e-CIS. I-antigen yakwamanye amazwe. Angizethembi izidakamizwa, imiyalo yazo ekhombisa ukuthi akunakwenzeka ukuhlola izakhiwo zayo ze-pharmacokinetic.
I-Afanasyev P.F. udokotela we-ultrasound, eSt
Umuthi omuhle we-antihypoxic ngokulondolozwa komphumela wezinyanga izinyanga ezingama-3-6. Leli thuluzi lusetshenziswa kabanzi esibhedlela sethu ku-Research Institute. I-Ankylosing spondylitis yokuqedwa kwezimpawu zesifo i-cerebrovascular kanye ne-discirculatory encephalopathy, imiphumela yokulimala kanye nokulimala kobuchopho kobuhlungu. Isiza ukuqeda ikhanda, i-migraines, imizwa yokukhathazeka, ithuthukisa umsebenzi wengqondo, njll.
