Umuthi ungowesigaba sezidakamizwa ze-heestatic, ukusetshenziswa kwazo ngezinjongo zephrophylactic nezokwelapha kungenxa yobukhona bomphumela we-antihemorrhagic emithini yokwelapha. Umphumela wemithi yesidakamizwa usekelwe emandleni wokulawula ukuqina kwemizwa kohlelo lokujikeleza kwegazi. Umuthi une-contraindication. Ukwemukelwa kwefomu elithile lomthamo kufanele kwenziwe ngokwemiyalelo yokusebenzisa.
I-ATX
B02BX01.
Khipha amafomu nokwakheka
Umenzi wethula izinhlobo ezi-2 eziphambili zokukhishwa kwezidakamizwa: amaphilisi nesisombululo.
I-Ethamsylate ingeyeqembu lezidakamizwa ze-heestatic.
Isithako esikhulu esisebenzayo kuzo zombili lezi zinhlobo yi-ethamylate (ngesiLatini - Etamsylate). Okuqukethwe kwengxenye kusisombululo (2 ml) akwedluli ku-125 mg, kwiphilisi - hhayi ngaphezu kwama-250 mg. Izakhi ezisizayo ekwakhiweni kwanoma iliphi ifomu lomthamo zisebenza njengabazinza.
Ukwakheka kwamaphilisi kufaka phakathi izinto ezilandelayo:
- i-polymer evumelana kalula;
- isitashi semifino (ummbila);
- i-acid entshontsha;
- imibala yokudla (kuya ngomenzi);
- ushukela wobisi (i-lactose).
Isixazululo siqukethe:
- i-sodium bicarbonate (bicarbonate);
- i-sodium pyrosulfite;
- amanzi ahlanziwe.
Okuqukethwe kwento esebenzayo kwisixazululo ayidluli ku-125 mg.
Amaphilisi wesakhiwo esiyindilinga esifanele, umbala omhlophe noma opinki nosayizi omncane. I-Chamfer kanye nengozi zikhona. Ngocezu olude lwethebhulethi, isisindo esimhlophe esimhlophe esimhlophe siyabonakala kahle. Ifomu lokuhlanganisa ifilimu elihlanganisa ifomu lomthamo liyatholakala. Ithebhulethi ligxiliwe kumaseli angama-10-mesh. lilinye.
Isixazululo somjovo sithululelwa kuma-ampoules angilazi acacile. Kukhona amamaki aluhlaza okwesibhakabhaka esitsheni esivulekile ohlongozwayo. Imijovo kuma-ampoules ifakwa emaphaketheni epulasitiki enani lama-5 pcs. Zombili lezi zinhlobo zemithamo zithengiswa emabhokisini amakhadibhodi. Imiyalo yokusebenzisa - iyatholakala.
Indlela yokusebenza
Indlela yokusebenza yesidakamizwa isuselwa kumphumela we-hemostatic womuthi.
Ngemithi ejwayelekile, ukuvunyelwa kwemithambo kutholwa njengokujwayelekile, kufaka phakathi imvume yokuqina. I-microcirculation yegazi iyabuyiselwa.
Ngezikhathi eziningi, umuthi wehlisa umthamo wamamenti. Umuthi uyakwazi ukuvusa ukwakheka kwe-thromboplastin. Ngaphansi kwethonya lomuthi, isilinganiso segazi elihlanganayo siyanda, njengoba kwenza ukunamathela kwamapuleti. Umuthi uvimbela ukuthuthukiswa kwe-thrombosis kanye nokwakheka kwezihibe zegazi. Izici ze-Hypercoagulant zomuthi azikho.
Ngaphansi kwethonya lomuthi, izinga lokuqina kwegazi liyakhuphuka.
I-Pharmacokinetics
Lapho uthathwa ngomlomo, ukuqhekeka kwefomu lomthamo kwenzeka emgodini wesisu. Umuthi uqala ukusebenza imizuzu engama-20-30 ngemuva kokufaka isicelo. Ukuhlushwa okuphezulu egazini kufinyelelwa ngemuva kwemizuzu engama-60. Umphumela wemithi uthatha amahora angama-6-7. Ukuqedwa kwesigamu sempilo kuthatha amahora angama-1,5-2.
Isixazululo ngomjovo we-intramuscular ngokushesha sisakazekela ezithweni ezithambile ngqo kusuka endaweni yomjovo. Umphumela wokwelapha wenzeka ngemuva kwemizuzu engu-15-30. Umuthi ufakwa emzimbeni wesibindi, kungakhathalekile ukuthi hlobo luni lokukhululwa. Ama-metabolites asebenzayo awekho. I-Excretion yenziwa izinso; akukho ngaphezu kwe-2% okususwe okungashintshiwe.
Okunqunyelwe
Ukusetshenziswa kwesidakamizwa ngezinhloso zokwelapha kwenziwa nge-pathologies engavusa ukopha. Lokhu kufaka phakathi isifo sikashukela kanye ne-hemorrhagic diathesis. Umuthi usetshenziswa kabanzi ekungenelweni kokuhlinzwa ezindaweni ze-ophthalmic, zamazinyo, ze-urological, ze-gynecological kanye ne-otolaryngic.
Umuthi usetshenziswa kabanzi ekungeneleleni kokuhlinzwa endaweni ye-ophthalmic.
Umuthi usetshenziswa ngesikhathi sokuya esikhathini ukuvimbela ukopha kakhulu. Ukusetshenziswa kwezinkinga ze-hemorrhagic kuvunyelwe ngenxa yezizathu zezempilo, kufaka phakathi ukusetshenziswa okuphuthumayo kokuphuma kwe-pulmonary kanye nesisu.
Contraindication
Ukusetshenziswa kwomuthi njengengxenye ye-monotherapy yama-hemorrhages enikezwa ukusetshenziswa kwama-anticoagulants akuvunyelwe.
I-contraindication eyinhloko yile:
- i-thrombosis
- i-thromboembolism.
Iziguli ezinesifo se-Hypersensitive ziyelulekwa ukuba zenqabe ukuthatha lo muthi.
Ungayithatha kanjani
Umuthi kufanele uphuzwe kungakhathalekile ukuthi hlobo luni lokukhululwa ngokuya ngethamo lomuthi. Umuthi uthathwa ngomlomo (ngamathebulethi), ulawulwa ngemisipha, ngokubuyiselwa emzimbeni, ngokwangaphakathi (isixazululo) nangaphandle. Ukufakwa umjovo (i-drip) esikhungweni sezokwelapha esikhethekile. Umthamo unqunywa uchwepheshe ngokuya ngesimo sesiguli.
Umthamo owodwa ovumelekile wokwelapha wesisombululo ngu-150-250 ml kathathu ngosuku. Izinga lansuku zonke lefomu lethebhulethi leziguli ezindala akumele lidlule amaphilisi ayi-6 ngosuku. Ngokwemiyalo, iphilisi alinconywa ukuba liphuzwe esiswini esingenalutho. Amathebulethi kufanele aphuzwe ngesikhathi sokudla noma ngemuva kokudla.
Ukusetshenziswa kwangaphandle kwenziwa ngokufaka isicelo sebhandeji ye-gauze efakwe kwisisombululo somuthi ngqo esilondeni.
Zingaki izinsuku
Ukusetshenziswa kwesidakamizwa kwenziwa ngezifundo. Isikhathi senkambo yokwelashwa siyizinsuku eziyi-10-14. Phakathi kwezifundo, udinga ukuthatha ikhefu lezinsuku ezingama-7-10.
Ngohlobo 1 sikashukela
Lapho welapha isifo sikashukela, uhlobo lomthamo olunqunywe uchwepheshe kufanele lubhekwe. Umthamo ophakanyisiwe wamaphilisi ngu-250-500 mg kathathu ngosuku izinsuku eziyishumi.
Lapho welapha isifo sikashukela, uhlobo lomthamo olunqunywe uchwepheshe kufanele lubhekwe.
Ukwethulwa kwekhambi kwenziwa ku / m noma / ngenani le-2-4 ml kabili ngosuku izinsuku eziyi-14. Kungcono ukusebenzisa ama-syringes ngezinaliti ezincane zobubanzi.
Imiphumela emibi
Uhlobo lomthamo okhethwe ngokungalungile lungavusa ukuthuthukiswa kwemiphumela emibi eminingana.
Amapheshana wesisu
Kusukela epheshaneni lesisu, ukushaya kwenhliziyo, ukugcwala kwenhliziyo kanye nokuhlanza, nobuhlungu be-epigastric kuyabonakala.
Izitho zeHematopoietic
Engxenyeni yezitho ze-hemopoietic, ukuthuthukiswa kwe-tachycardia, gxuma ekucindezelweni kwegazi, kubuhlungu esifundeni senhliziyo.
Ukuthatha umuthi kungaphazamisa ukuhamba kwegazi, ngenxa yalokho isikhumba siba yi-cyanotic.
Isistimu yezinzwa ephakathi
Ukusuka ohlangothini lwesistimu yezinzwa ephakathi, isiyezi, ukuphazamiseka kokulala (ukozela noma ukuqwasha), kungavela ukuvevezela kwemikhawulo.
Imiphumela emibi yokuphuza umuthi ifaka ukuphazamiseka kokulala.
Kusuka ohlelweni lomchamo
Ezimweni ezingavamile, kukhona ukwephulwa kokuphuma komchamo.
Allergies
Umuthi awukuvusi ukungezwani komzimba.
Imiyalo ekhethekile
Ukusetshenziswa kwomuthi ezinganeni kungadinga ukulungiswa kohlobo lomthamo. Izingane zenqatshelwe ngokuphelele ukunikeza amaphilisi angaphezu kwama-2-3 ngosuku; umthamo ngamunye ubalwa ngokuya ngesisindo somzimba wengane (kuze kufike ku-15 mg / kg isisindo).
Ukuhambisana notshwala
Umuthi awuhambisani notshwala. I-Ethanol ehambisana nesithako esisebenzayo efomini lomthamo ibangela ukudakwa okunzima komzimba futhi inyusa umthwalo esibindini.
Umuthi awuhambisani notshwala.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusetshenziswa kwalesi sidakamizwa maqondana nabesifazane abakhulelwe (i-trimester) kwenziwa ngaphansi kokuqashwa kukadokotela futhi ngenxa yezizathu zempilo. Akukho mininingwane eqondile mayelana nokulimazeka okungaba khona ku-fetus.
Ukweqisa
Umenzi akazange anikeze imininingwane ngokweqile.
Ukuxhumana nezinye izidakamizwa
Akunamininingwane ekuxhumaneni kwemithi ye-antihemorrhagic nezinye izidakamizwa.
Ama-Analog
Kunezichazi eziningi eziphambili (ngokusho kwe-ATX) nama-generics.
Okusemqoka kufaka phakathi:
- U-Eskom. Itholakala njengesisombululo somjovo. Isithako esikhulu esisebenzayo siyefana nesiqalo. Vimbela ukopha kwe-etiologies ehlukahlukene, uqinisa izindonga zemithambo yegazi. Izindleko ezisondele - ama-ruble angama-90-120.
- Dicinon. I-Hemostatic, i-analogue eqondile yesakhiwo (ekwakhekeni) yoqobo. Kutholakala ngesimo sesisombululo namaphilisi. Imunca ngokushesha futhi isatshalaliswe. Kukhona ukuphambana. Intengo emakhemisi isuka kuma-ruble ayi-130.
IGenerikhi ifaka:
- Tranexam. Umuthi one-hemostatic osebenza njenge-inhibitor ye-fibrinolysis. Isheshisa ukwakheka kwe-plasmin. Kuyatholakala ngesimo sethebhulethi. Ivimbela ukuthuthukiswa kokopha, kufaka phakathi i-uterine, amathumbu kanye ne-pulmonary. Intengo - kusuka kuma-ruble angama-80.
- IVikasol. Umuthi we-antihemorrhagic, okuyi-analogue ye-Vitamin K. Indlela yokukhishwa yisisombululo somjovo. Isibonakaliso esiyinhloko sokusetshenziswa yi-hemorrhagic syndrome. Izindleko - kusuka kuma-ruble ayi-120.
Cishe wonke ama-analogues adinga umuthi ovela kumakhemisi. Ukuzikhethela okuzimele kokufaka esikhundleni akufakiwe.
Imibandela yekhefu lekhemisi
Noma yiziphi izinhlobo zokukhishwa zitholakala ekubhalweni kadokotela.
Intengo ye-Etamsilat
Izindleko zomuthi (ngokuya ngesimo sokukhishwa) ziqala kusuka kuma-ruble ayi-120.
Izimo zesitoreji somuthi i-Ethamsylate
Umuthi kumele ugcinwe endaweni ekhethekile futhi emnyama ekhethekile. Ukuvezwa kwelanga kufanele kugwenywe. Kwenqatshelwe ngokuphelele ukuvumela izingane nezilwane ezifuywayo endaweni yokugcina umuthi.
Isikhathi sokuphelelwa yisikhathi
Kwenqatshelwe ukugcina umuthi (noma ngabe ungasifomu yomthamo) izinyanga ezingaphezu kwezingama-36.
Ukubuyekezwa kwe-Ethamsilate
UVladimir Starovoitov, udokotela ohlinzayo, uNizhny Novgorod
Ngibheka ukuthi umuthi uyasebenza. Ngokuzijwayeza, ngifaka isicelo isikhathi eside. Intengo yomuthi incane, eyenza lula ukutholwa kwanoma yiluphi uhlobo lomthamo futhi yenze umuthi utholakale kalula kuzo zonke izingxenye zabantu. Imvamisa ngifaka i-hemostatic ekwelashweni kabusha njengezindlela zokuvimbela ukopha ngemuva kokuhlinzwa.
Ngincoma ukuthi iziguli zami zithathe okungenani ubuncane amahora angama-1.5-2 ngaphambi kokuhlinzwa okuhlongozwayo. Ngalesi sikhathi, umuthi udakwe ngokuphelele, uqala ukwenza isigamu sehora ngemuva kokufaka isicelo. Umuthi unciphisa ubungozi bokuphuma kwe-capillary ne-venous. Isebenza ikakhulukazi njengengxenye yokwelapha okuyinkimbinkimbi.
Izikhalazo ngemiphumela emibi evela ezigulini ayizifanelanga. Isizathu esiyinhloko sokuthi zingavela ukwanda okuzenzakalelayo komthamo obekwe udokotela. Imiphumela emibi ezimweni eziningi idlula ngokuzimela ngemuva kwezinsuku ezingama-2-3.
ULarisa, oneminyaka engama-31 ubudala, Magnitogorsk
I-fetus iqhuma emavikini ayi-16. Ngemuva kokuhlanza, kwaqhuma ukopha. Ngemuva kokuhlolwa, udokotela wafaka inqwaba yemithi ye-antihemorrhagic. 1 umjovo awuzange usize, kwadingeka ngibhoboze inkambo. Ukuphuma kwegazi kwavalwa, umuthi wafakwa ekhaya ezinye izinsuku ezi-5. Ngemuva kokuhlinzwa, umjikelezo wokuya esikhathini waphazamiseka. Ukukhishwa kwakukuningi, ngesikhathi sokuya esikhathini waqala ukuzizwa ephethwe yibuthakathaka. Ngaphinde ngaya ku-gynecologist. Udokotela wathi ukwehla kwegazi kuqinile, kuyadingeka ukuthi ijikeleze umjikelezo ngokushesha.
Wathatha umuthi one-heaticatic ngesimo samathebhulethi. Ekuqaleni kokwelashwa, waphuza ipilisi elilodwa kathathu ngosuku, ekhulisa kancane kancane amaphilisi akhe kanye kanye. Udokotela uxwayise ngokuthi akunakwenzeka ukukhansela ubambe ngamawala, kubalulekile ukunciphisa kancane kancane umthamo. Imiphumela emibi yavela ngosuku lwe-2 lokwelashwa. Ekuseni ngemuva kokuphuza iphilisi, ngezwa ukuhlaselwa ngamandla kwenhliziyo.
Esikhathini sasemini, i-reception yanquma ukungaphuthelwa, iphuza iphilisi ngemuva kokudla. Kwakungekho-nausea, kepha kwakukhona ukushisa kwenhliziyo okuncane, okuye kwahamba ngemuva kwamahora ambalwa. Izinsuku zokuqala ayengakwazi ukulala isikhathi eside, khona-ke ubuthongo babuyela kokujwayelekile.
UMaxim, oneminyaka engama-43 ubudala, u-Astrakhan
Sekuyisikhathi eside ngigula i-hemophilia. Ukuze ulondoloze impilo enhle, uyaphoqeleka ukuthi athathe imishanguzo ye-anti-hemorrhagic njalo. Ngaphambi kwalokho, wayegwema umuthi wendabuko, wazama ukuzisindisa ngemithi yabantu, kepha kwaba kubi kakhulu. Ngemuva kokuqokwa okulandelayo, udokotela weluleke ukuthatha umuthi obizayo onomphumela we-hemolytic. Ngenxa yokungazethembi ngokwezimali, ngiphuza inkambo eyodwa kuphela yalo muthi. Udokotela wangicela ukuba ngikhethe ithuluzi elingabizi kakhulu.
Inketho yayamiswa kumuthi ongabizi ngesakhiwo esifanayo nesidakamizwa esibizayo. Ngawuthenga lo muthi ekhemisi ngomuthi onikezwe wona. Okokuqala ngithathe i-1 ithebhulethi izikhathi ezimbili ngosuku, ke, ngemvume kadokotela, ngakhulisa umthamo omncane. Ngifuna ukuqaphela ukuthi imiphumela ye-hemolytic yomuthi iyaqhubeka. Kuyo yonke iminyaka yokusebenzisa, imiphumela emibi yenzeke ngesikhathi esingu-1 ngenxa yokuphatha okungalungile. Umuthi akufanele udakwe esiswini esingenalutho: kuvela isicanucanu. Ngiphuza amaphilisi ezifundweni ezifika emasontweni ama-2 ngekhefu lezinsuku ezingama-6-7. Wanelisekile ngomphumela.
