Kuze kube manje, inkinga yokulwa ne-atherosulinosis iyinkinga enkulu kwezokwelapha. I-cholesterol ephakanyisiwe iyimbangela yokuqala ye-atherossteosis nakho konke ukubonakaliswa kwayo kwemitholampilo.
Kepha abantu abaningi abayazi inkinga yamazinga aphansi wegazi lipid. I-cholesterol ephansi emadodeni nakwabesifazane ibonisa isici ohlelweni lwe-lipid metabolism. Isizathu esikhulu sokwephulwa okunjalo kungukudla okunganele kwe-cholesterol ngokudla noma ukwephulwa kokuqalwa kwayo kwendalo. Lesi simo singasho futhi ne-overdose yezidakamizwa ezithathiwe ukulwa nezibonakaliso ze-atherosclerosis.
Isakhiwo samakhemikhali se-cholesterol utshwala obuyinkimbinkimbi. Amamolekyuli ayo yi-hydrophobic, okusho ukuthi ayinamanzi. Egazini, zingahanjiswa kuphela kusetshenziswa amaprotheni othwala.
Kakhulu, ama-lipid athuthwa ngokuhambisana ne-albhamuin. Futhi, igazi liqukethe ukumiswa kwamahhala kwe-cholesterol ephelele.
Izinhlobo ze-lipid eziyinkimbinkimbi ngamaprotheni, ahlukaniswe ngamanani wokubala wokuqukethwe kwamamolekyuli e-cholesterol:
- density lipoproteins, babe nomphumela we-atherogenic; ukugxila kwabo kufanele kugadwe kakhulu;
- ama-lipoproteins aphansi kakhulu nawo ayingxenyana ye-atherogenic;
- umthamo omkhulu we-lipoproteins, omelela okuyinkimbinkimbi "ewusizo" enezakhiwo ze-antiatherogenic;
- ubukhulu be-lipoproteins ephezulu kakhulu futhi banomphumela we-antiatherogenic obaluliwe.
Ukwehla kwenani lezingxenyana ze-anti-atherogenic kanye nokwenyuka kwezingxenyana ze-atherogenic kuyimbangela yezinguquko ze-atherosulinotic ezindongeni zemithambo yegazi.
Lokhu kungalingani kudinga indlela ehlelekile ekuvinjelweni kwezinkinga nokwelashwa.
Umsebenzi we-cholesterol emzimbeni
Ama-molecule e-cholesterol ayizinto ezibaluleke kakhulu zokuphendula okuningi kwe-biochemical emzimbeni. Ukungapheleli kwabo kuholela ekwephuleni umsebenzi wokwenziwa futhi kubangela izinguquko eziphikelelayo zokuziphatha emzimbeni.
Ukubaluleka kokuzalwa kwe-cholesterol:
- Ngaphandle kwe-cholesterol, ukwakheka kwama-hormone ocansi nama-adrenal mahomoni akunakwenzeka.
- Kubalulekile ekwakheni i-Vitamin D ngaphansi kwethonya lemisebe ye-ultraviolet.
- Ihlanganyela ekwakhiweni kwama-bile acids, okuyizinto ezibalulekile ze-bile futhi ezihilelekile ekugayweni kokudla.
- Kuyinto ebaluleke kakhulu odongeni lweseli.
- Ikhuthaza ukukhiqizwa kwezinto eziphilayo ezisebenzayo - i-serotonin.
- Ibamba iqhaza ekwakheni cishe wonke ama-membranes weseli, futhi iphinde imelane nemiphumela emibi yama-radicals yamahhala.
- Ukuzibandakanya ngenqubo yezinqubo zokwenziwa, okubaluleke kakhulu ekugcineni inqubo evamile yokukhula.
Ama-molekyuli e-cholesterol ayadingeka ukuze kugcinwe amandla emisipha, umsebenzi wezinzwa we-neurocytes, nobuningi bezitho zezinto eziphilayo nezingabonakali zezicubu zamathambo.
Iphinda ithinte amanzi-usawoti kanye ne-mineral metabolism.
Ihlanganyela ekwakhiweni kwe-insulin ye-hormone nasenqubo yokutholwa kwamavithamini ancibilikiswa ngamafutha. Futhi, izingxenyana ze-antiatherogenic zinikeza ukuvikeleka kwe-vascular ngokumelene ne-atherosulinosis.
I-cholesterol ephansi ingasongela:
- ukuthuthukiswa kokudangala komoya omnene, olinganiselayo noma obukhali obukhulu ngokuba khona kwemicabango engapheli futhi yokuzibulala maqondana nokucindezelwa kokukhiqizwa kwe-cholesterol;
- isifo sokuqaqamba kwamathambo;
- ukungazali ngokuyinhloko kwabesilisa nabesifazane;
- ukwephulwa kwe-libido;
- Ukukhuluphala ngokweqile
- i-hyperthyroidism;
- isifo sikashukela
- i-hypovitaminosis yamavithamini anyibilikayo;
- ngokushoda kwezingxenyana ze-anti-atherogenic ze-lipoprotein, ukuthuthukiswa kwezimo ezinqala njengokuphazamiseka okukujikeleza kokujikeleza kwento kanye ne-acute coronary syndrome kungenzeka.
I-cholesterol engezansi kokujwayelekile kwabesifazane, okusho ukuthi ikhathaza umbuzo wabameli abaningi besifazane.
I-pathology enjalo ingaholela ekuchithekeni ngokungafanele kanye nokuzala ngenxa yokuntuleka kwama-hormone ocansi.
Izizathu zokwehlisa i-cholesterol
Iningi labantu ngemuva kweminyaka engamashumi amane lihlushwa ukungalingani kumanani we-lipid.
Izinguquko kulokhu kuhlaziya ziyingozi futhi zingakhombisa ukuthuthukiswa kwe-atherossteosis.
Ukukhula kwe-cholesterol "embi", izingxenyana ze-atherogenic kanye nokwehla kwezingxenyana ezixinene kakhulu kuboniswa ngokwakhiwa komfutho wegazi ophakeme, izifo zenhliziyo ezi-coronary kanye ne-endarteritis eqeda amandla.
Izimbangela zokungalingani kwe-lipid yilezi:
- Izifo zesibindi nokukhipha okulimazayo kwe-bile. Ukungasebenzi kweseli kwesibindi kunethonya elibi ekwakhekeni kwamaprotheni e-cholesterol kanye nokuthuthwa kwe-lipid transporter, ngoba kukhiqizwa ama-cholesterol amangqamuzana esitho.
- Ukudla okungenamsoco noma ukudla, ngaphandle kokudla kwama-acid amaningi we-polyunsaturated.
- Ukusetshenziswa isikhathi eside kwezidakamizwa ezithile (ama-statins, izidakamizwa ze-antihypertensive, ama-antibhayoriki).
- I-Malabsorption ngenxa ye-organic pathologies yokugaya ukudla.
- Ukumelana nokucindezelwa okuphansi kanye nesizinda esibuhlungu se-psycho-psych.
- I-Hyperthyroidism.
- Ukudakwa okungapheli komzimba ngothuli lwensimbi esindayo, i-mercury, njll.
- Ukukhula okusebenzayo (okujwayelekile kwabasakhulayo).
- UPaul Indoda isengozini yokushintshwa kwephrofayili ye-lipid kunowesifazane.
- Izinguquko ezihlobene nobudala. Ukuguga kuyinto ebeka engcupheni yokushoda kwezinto eziningi ezisebenza ngokuphila.
- Ukudla okungaxutshiwe.
- Umkhuhlane isikhathi eside ngenxa yezinqubo ezinzima zokutheleleka.
- Isifo Sokulwa Nezifo Zesifo Sikashukela
Kwezinye izimo, ukuntuleka kwe-cholesterol kuyindlela eyi-pathology esebenzayo (abasubathi, izisebenzi ezimbonini ezinobungozi) futhi zidinga ushintsho emsebenzini wobungcweti.
Izimpawu zokuthuthuka kwalesi sifo
Ukuhlolwa kwesiguli okunenjongo akuvamile ngokwanele ukuthola ukusweleka kwe-cholesterol.
Ukuze acacisele ukutholwa, udokotela kufanele enze ukuhlolwa kwegazi okune-biochemical kweziguli.
Ngakho-ke, udokotela uzokwazi ukuhlola isilinganiso se-LDL kumazinga we-HDL, futhi athole imbangela yokwephulwa kwangempela.
Kepha kunezimpawu ezithile zokushoda kwe-cholesterol emzimbeni:
- ukukhula okungazelelwe kobuthakathaka obunzima bemisipha;
- ukukhula kwama-lymph node (ngokutheleleka, i-etiology etiology yenqubo);
- isifiso sokudla (uma kunezinkinga zokugaya ukudla nesibindi);
- i-steatorrhea (izindle ezinokuhlanganiswa okukhulu kwamafutha);
- ukwephulwa komsebenzi we-Reflex;
- Ukudana
- kwehla i-libido;
- izinhlungu zenhliziyo
- ingcindezi.
Amazinga we-cholesterol kufanele aqashelwe ezigulini ezinalezi zimpawu, kubo bonke abantu abaneminyaka engaphezu kwamashumi amane ubudala, kanye nakubantu abasengozini.
Le mikhakha elandelayo yabantu ingeyeqembu lengozi:
- Ababhemayo.
- Abantu abahlushwa ukukhuluphala nesifo sikashukela.
- Abantu beqembu labantu abadala.
- Ukuhola indlela yokuphila noma yokwakha.
- Abalandeli bokudla okusheshayo nokunye ukudla okungenamsoco.
Kubalulekile ukuhlaziya njalo ama-lipids egazi kubantu abanesifo somfutho wegazi ophakeme, isifo sikashukela, abanomlando we-acute cerebrovascular ajali noma i-acute coronary syndrome, kanye neziguli ezinesifo senhliziyo.
Izindlela Zokukhulisa i-Cholesterol
Ngaphambi kokuqhubeka nokwelashwa, kubalulekile ukuthi uhlolwe ngokuphelele futhi uthole imbangela yangempela yokuntuleka kwe-cholesterol.
Okokuqala, ukwenza ngokwejwayelekile izinga le-lipids, ukulungiswa kokudla kufanele kwenziwe. Amafutha emifino nezinhlobo ezithile zezinhlanzi kufanele afakwe kwimenyu. Lokhu kudla kuqukethe inani elikhulu lamafutha we-polyunsaturated, ikakhulukazi ama-Omega-3 nama-Omega-6 fatty acids, abandakanyeka ngokuqinile emgudwini we-lipid futhi avimbele ukuthuthukiswa kwezilonda zesibindi ze-atherosclerotic. Lamafutha acid angakhuphula lizinga le-anti-atherogenic lipids emzimbeni bese anciphisa ingxenyeni ye-atherogenic.
Imenyu enezinga eliphansi le-cholesterol “enempilo” iyindlela ejwayelekile yokudla kokudla futhi isekelwe ezimisweni zokudla okunempilo. Ukuqeda ukushoda kwe-lipids ezuzisayo, imenyu kumele ifake:
- imifino enothile kakhulu nephansi;
- isinkwa esiphelele sokusanhlamvu;
- imikhiqizo yobisi;
- izitsha ze-soya;
- inyama enciphile;
- okusanhlamvu okuncane kwe-gluten;
- izithelo zonyaka nezithelo;
- ama-isiphuzo neziphuzo zezithelo ngaphandle koshukela ongeziwe;
Ngaphezu kwalokho, kufanele uyeke imikhuba emibi bese wethula indlela yokuphila esebenzayo. Izimo ezibucayi eziholela ekukhubazekeni okukhulu noma ngisho nokufa kungaholela ekuphazanyisweni kwe-lipid metabolism.
Ubungozi be-cholesterol ephansi buchazwe kule vidiyo kule ndatshana.
