Ama-pancreas ahlanganisa izakhi ezisebenzayo zezinto eziphilayo - ama-enzyme nama-hormone abamba iqhaza ngenqubo yokugaya. Enye yalezi zinto yi-pancreatic elastase, ekhishwa ngqo kuyi-duodenum.
Ukuqoqwa kwale nto kukhombisa isimo somzimba sesitho sangaphakathi, ukusebenza kwawo, kanye nokuguqulwa kwezimilo. Ukunquma izinga, kuyadingeka ukuhlola indle yesiguli.
Ngokushoda noma ngokweqile kwe-enzyme, izimpawu ziyabonakala - ukwanda kwegesi, ukuqhakaza ngemuva kokudla, izihlalo ezikhululekile, isibonakaliso sokukhiqizwa kwamagciwane esibelethweni, njll. Izimpawu.
Ukuntuleka kwe-elastase kukhuluma ngokuthuthukisa i-pancreatitis nezinye izifo ezihambisana nepheshana lesisu. Cabanga ukuthi lizinga kunqunywa kanjani, nokuthi imiphumela yokuhlaziya inqunywa kanjani.
Yini le
I-pancreatic elastase iyinto enzyme ekhiqizwa yi-pancreas. Le ngxenye ibamba iqhaza ngenkuthalo kwinqubo yokuhlukanisa izingxenye zamaprotheni kuma-amino acid.
Umsebenzi we-enzyme unqunywa izinkomba ezimbili - i-intracecretory - ukukhiqizwa kwe-insulin nokulungiswa kwe-carbohydrate metabolism, i-exocrine - ukubamba iqhaza kwinqubo yokugaya ukudla.
Ngemithambo yesitho sohlelo lokugaya ukudla, i-pancreatic elastase ingena emathunjini amancane. Uma ukusebenza kwe-duodenum kukhubazekile, ukuqina kwe-enzyme kuyancipha.
Izinga le-Elastase lophawu olujwayelekile olusiza ukuthola umsebenzi we-pancreatic onganele. Imvamisa, lolu cwaningo lwenziwa kanye nezinye izindlela zokuxilonga - i-coprogram ye-pancreatitis, ukuzimisela kwe-amylase ephelele, i-UAC.
I-Elastase idlula kulo lonke leli pheshana esiswini, ngenkathi izici zayo zokulinganisa nobuningi zingashintshi ngokujwayelekile. Ukuhlaziywa kwezindunduma ze-pancreatic elastase kwazisa ngokufanele udokotela ngokuphulwa.
I-enzyme ye-pancreatic, ngokuya ngokusebenza kwayo, inezinhlobo ezimbili:
- I-Elastase-1 (i-pancreatic). Kukhiqizwa emangqamuzaneni angaphakathi e-pancreas bese kungena i-lumen yamathumbu nezinye izingxenye ze-enzyme ngendlela ye-proelastase. Lapho, ihlangana ne-hormone trypsin, iguquke ibe yi-elastase futhi ihlanganyele enqubweni yokuwohloka kwamaprotheni. I-enzyme ibonakala ngokukhethekile; ayinqunywa kwezinye izitho zangaphakathi noma izicubu ezithambile;
- I-Elastase-2 (i-serum). Umuthi othi, ngokumelene nesizinda senqubo yokuvuvukala kumanyikwe, ungena egazini ngokusebenzisa ulwelwesi lweseli olonakalisiwe. Esigabeni esibi se-pancreatitis, inani laso landa kakhulu. Lokhu kungatholakala esifundweni soketshezi lwezinto eziphilayo. Izinga liqala ukukhula ngemuva kwamahora ayi-6 kusukela ekuqaleni kwe-pathology, ifinyelela phezulu ngosuku lwesibili. Lokhu kuyingxenye yokubola okuhlala isikhathi eside, ngakho-ke ihlala ohlelweni lokujikeleza izinsuku ezingafika kwezihlanu, kwesinye isikhathi ngesonto.
Ukunquma izinga le-pancreatic elastase, kufakwa indle. Ukuhlaziywa kwenziwa kunoma yisiphi isikhungo sezokwelapha. Udokotela ohlinzayo noma i-gastroenterologist unikeza inkomba kuyo.
I-Pancreatic Elastase Study
Kwi-Coprology, kuhlolwa ukuhlolwa kwe-fecal ezimweni okusolwa ukuthi i-cystic fibrosis, i-pancreatitis engapheli, i-cholelithiasis, ukungasebenzi kahle kwe-pancreatic, isifo sikaCrohn. Ukuhlaziywa kuphinde kunqunywe uma umlando wokuhlaselwa umqubuko, i-pancreatic tumor, ukubambezeleka ukukhula komzimba (enganeni).
Ukuhlaziywa kuhilela ukutadisha indle elabhorethri. Umthamo wokuhlaziywa ngu-10-15 g wezindunduma. Njengoba i-enzyme ihlotshaniswa nokudla kokudla, ukulungiselela kuyadingeka ngaphambi kokuhlolwa.
Emahoreni angama-72, udinga ukuyeka ukuphuza amakhambi ngamafutha (ama-laxatives, isiraphu, njll.), I-Pilocarpine - umuthi usiza ukwandisa ukucasulwa kwama-enzyme wokugaya, ukwandisa ithoni yezindonga zamathumbu. Awukwazi ukuthatha umuthi nge-belladonna, ngoba uvuselela izicubu ezibushelelezi zamapheshana emathunjini.
Ukungafaki umphumela ongamanga, kwenqatshelwe ukwenza izinqubo ze-enema - yokuhlanza noma yokwelapha. I-contraindication yi-radiografikhi ngokwethulwa kwezici zokuhlukanisa.
Kungcono ukuqoqa izinto ezibonakalayo engxenyeni yokuqala yosuku. Ekuseni, izindunduma ziqoqwa esitsheni esingenalutho zisebenzisa i-spatula ekhethekile, ziyiswe egumbini lokucwaninga. Uma lokhu kungenzeki, khona-ke indle yakusihlwa nayo iyavunyelwa - zigcinwa esiqandisini emnyango.
Ukuthola ama-pathologies ahlukahlukene, kuhlola umkhiqizo wokuphila komuntu, kusetshenziswa indlela ye-ELISA - i-enzyme exhumene ne-immunosorbent assay esekelwe ekuphenduleni - ama-antibodies-antigens.
Izinzuzo zendlela:
- Ngokunemba okungu-100%, ukunqunyelwa kokugula okungapheli kwe-pancreatic elastase kunganqunywa.
- Ngokucatshangelwa kwama-95% anqume isifo se-pancreatic esingamahlalakhona.
- Ungasikhomba lesi sifo ekuqaleni kwengqondo.
Izinguquko emsebenzini we-enzyme yokugaya ukudla zibonakala njengenqubo ehamba kancane, ngakho-ke kungakuhle ukuthi kwenziwe ukuhlaziya okunjalo kungabi ngaphezu kwezikhathi eziyi-1-2 ngonyaka, ngoba azikho izinguquko ezibalulekile ngalesi sikhathi.
Imvelo nokuphambuka
Ukwehla kokuhlaziywa kukhombisa ukwehluleka nezinkinga emzimbeni wokugaya ukudla. Uma ucwaningo lukhombise inani le-500 mg ngegramu ngayinye yezinto ezihanjiswa, khona-ke lokhu kuvamile, lo ngumkhawulo ophezulu wesimo esijwayelekile. Umbundu ophansi ngu-200 mg. Ngokufanelekile, ucwaningo kufanele lukhombe inkomba ephakathi, ekhombisa isimo esihle sokuphila nokusebenza kwamanyikwe.
Uma inani liboniswa kwelebhu yelabhoratri eliseduze kakhulu nomkhawulo ophansi noma ongaphezulu wesimo esejwayelekile, khona-ke kungahlolisiswa ukuhlolwa okwengeziwe. Kwezinye izimo, imitholampilo isusa izinkomba ze- "standardity" ngoba zithuthukisa isilinganiso sazo sokuhlaziywa kwezindunduma.
Ngomphumela ofinyelela ku-200 mg, bakhuluma ngobumnene
ngesilinganiso esilinganiselwe sokuntuleka kwe-exocrine. Ezithombe ezinganakwa ngokumelene nesizinda sokuntuleka okukhulu kwe-exocrine, ukuqoqwa kwe-enzyme kungaphansi kwe-100 mg.
Uma i-pancreatic elastase in feces ingaphezu kwama-500 mg, khona-ke ezinye izindlela zokuxilonga ziyanconywa. Njengomthetho, lo mphumela wokuhlaziywa uvame ukuhambisana nezikhalazo zesiguli sobuhlungu esiswini.
Izinga eliphansi libonisa isifo:
- I-pancreatitis e-acute noma engamahlalakhona;
- I-cystic fibrosis;
- Isifo sikashukela mellitus noma ngabe hlobo luni;
- I-Oncology;
- I-granulomatous enteritis.
I-pancreatic elastase engaphezu kwe-500 mg ingahle ibonise ukuthuthukiswa kwenqubo ye-oncological, i-pancreatitis ene-acute noma i-cholelithiasis. Ukuqinisekisa noma ukwenqaba ukuxilongwa kokuqala, kunconywa okunye ukuhlolwa kwegazi, kuthi lapho sebeqala ukwelapha isiguli.
Inani le-enzyme yokugaya ibonakala lingeyona inkomba eyisisekelo ekuxilongeni. Ucwaningo lunikezwe ngokuhambisana nezinye izindlela zokubona i-pathologies yamanyikwe.
Imininingwane ngemisebenzi nama-enzyme ama-pancreas inikezwe kuvidiyo ekulesi sihloko.
