Zonke izinqubo emzimbeni womuntu zilawulwa ngohlelo oluphakathi lwezinzwa nama-hormone akhiqizwa yizitho ze-endocrine. Indlela elungisiwe ivumela ukuthi uvumelane nezimo ezisheshayo zangaphandle nezangaphakathi.
Ama-pancreas yisitho esiyingqayizivele esingabambi nje kuphela ezinhlelweni zokugaya, kodwa futhi sivela njengohlobo lwe "fektri" oluhlanganisa izinto ezidingekayo empilweni ejwayelekile.
Isitho sangaphakathi siqukethe ingxenye ye-endocrine, ekhuthaza ukukhiqizwa kwama-enzymes wokugaya kanye nama-isanc we-pancreatic, lapho ama-hormone e-pancreatic ahlanganiswa khona. Basiza ukulawula i-carbohydrate, amaprotheni kanye namafutha metabolism.
Ngisho nokungasebenzi kahle ekusebenzeni kwesitho kungaholela emiphumeleni emibi. Ukushoda noma ukweqisa kwama-hormone kuphazamisa ukusebenza kwezitho zangaphakathi.
Ama-hormone aphambili ahlelwe ngamanyikwe
I-hormone eyinhloko engavimbela amanyikwe yi-insulin. Yi-polypeptide efaka ama-amino acid angama-51. Amaseli weBeta atholakala kuma-ispanc picreatic anesibopho sokuqamba kwawo.
I-insulin ye-hormone ikhiqizwa kuma-pancreas, yenza imisebenzi eminingana. Inesibopho sokulawula ushukela emzimbeni, isiza ekuvimbeleni ukwakheka koshukela esibindini, futhi isize ukunciphisa 
izinga lokubola le-glucagon.
Uma "i-biochemistry" enjalo yephulwa emzimbeni womuntu, khona-ke kukhona ukwanda ushukela wegazi, okwandisa amathuba okuthola isifo sikashukela kaningana.
I-insulin yamaprotheni isebenzisa ukukhululeka kwamafutha acid. Kuthinta ukukhiqizwa kwezinto zomgudu wesisu, ama-hormone okukhula kanye nama-estrogens.
Ngaphezu kwe-insulin, ama-pancreas ahlanganisa izinto ezilandelayo:
- IGastrin.
- Amilin.
- I-pancreatic polypeptide.
- I-Glucagon.
- I-peptide.
I-Lipocaine ingabhekwa njenge-hormone yesibili ekhiqizwa yisitho sangaphakathi (ngaphezu kwe-insulin). Inqanda ukukhula kwesibindi esinamafutha, ivuselela i-lipotropic metabolism.
Imisebenzi yamahomoni
I-insulin yi-hormone ethinta wonke amaseli emzimbeni. Ukusebenza okuyinhloko kwento kugcina ushukela wokugcotshwa koshukela ezingeni elidingakalayo. I-hormone ibangela izinqubo eziningi ze-biochemical emzimbeni ezinikeza umphumela oyifunayo.
Inani elincane le-glucose lihlala litholakala esibindini nasemisipha, lokhu kuyindawo yokugcina umzimba womuntu. Lesi sitoko sivezwa ngesimo se-hormone glycogen, okuthi, uma kunesidingo, siguqulwe sibe yisimo sayo sokuqala. Ngamanye amagama, iguqulwa ibe ushukela. Ukuqanjwa kwe-Glycogen kwenzeka esibindini, amaseli amhlophe egazi nezicubu zemisipha. IHormone iyindlela eyinhloko yama-carbohydrate emzimbeni womuntu.
I-Glucagon ingenye into yamanyikwe. Kuyasiza i-glycogen ukuthi idilize ukukhipha i-glucose; ikhuthaza ukuhlukana kwe-lipid, okuholela ekukhupheni i-lipase ebilisiwe kumaseli wamafutha.
Imisebenzi ye-somatostatin:
- Yehlisa ukugxila kwe-glucagon.
- Ibambisisa ukuqeda ijusi esiswini.
- Ibambezela ukuvela kwe-hydrochloric acid.
- Ivimbela ukukhiqizwa kwama-enzymes we-pancreatic.
- Yehlisa ivolumu yegazi emgodini wesisu.
I-pancreatic polypeptide itholakele muva nje. Umphumela we-endocrine hormone ungaqondakali ngokuphelele.
Iningi lososayensi liyavuma ukuthi le nto inomthelela "ekusindisweni" kwama-enzyme wokugaya ukudla we-pancreatic.
Ucwaningo lwelabhoratri lwamanyikwe
Ukuhlaziywa kwama-enzymes e-pancreatic ukuhlolwa kwegazi okuqinisekisa ukutholwa kwazo zonke iziphazamiso ezinhlobonhlobo zama-pathogenesis emsebenzini kanye nesimo sesitho sangaphakathi. Isetshenziselwa ukuthola izifo ze-pancreatic.
Ku-endocrinology, lolu cwaningo lunezinkomba eziningana. Kubekelwe izimpawu zomtholampilo zezifo zesitho sangaphakathi, kuyanconywa nokuthi kusolwe i-hypofunction noma hyperfunction yamanyikwe.
Imiphumela yocwaningo isiza ekuhloleni ukusebenza kwesitho sangaphakathi, ubungako bomonakalo; hlukanisa lesi sifo kwezinye izifo. Ngaphezu kwalokho, kuhlaziywa kunconywa ukuqapha iziguli ezine-pancreatitis engapheli, i-cholelithiasis nezinye izifo; khomba i-tumor neoplasms kuma-pancreas.
Ukuhlaziywa kwenziwa kumuntu okhulile nengane. Ukuqeqeshwa okukhethekile akukho. Into esemqoka ukuthi awukwazi ukubhema imizuzu engama-30 ngaphambi kokukhipha amasampula egazi. Njengombhalo webhayoloji, kusetshenziswa uketshezi olungene emzimbeni.
Okuqukethwe kwezinkomba ezilandelayo kunqunywe:
- I-C-peptide inqunywa yi-enzyme assay.
- Ukunqunywa koshukela ku-plasma yegazi.
- I-Lipase inqunywa indlela ye-colorimetric.
- I-Amylase isamba se-serum yegazi, i-bilirubin ephelele, i-pathobiochemistry ye-cholinesterase.
- Amaprotheni asebenzayo.
Uma, ngokusho kwemiphumela yokuthwetshulwa, umsebenzi wama-enzymes we-gland ukhuphukile, izinga leprotheyini elisebenzayo lenyukile, lokhu kubonisa indlela ebabazekayo ye-pancreatitis. Amazinga we-Pathological kashukela ne-C-peptide akhombisa ukungasebenzi kwesitho sangaphakathi.
Ukuhlolwa kwe-pancreatic kunqunywe kumacala alandelayo:
- Ukusolwa kwesimila.
- Ngezimpawu zokulimala okungenzeka kwesitho (izinhlungu esiswini engenhla, ukugabha, ukuqunjelwa kwesitofu - lezi zimpawu zingakhombisa ukwephulwa okukhulu, kuze kufinyelele ekuphazanyisweni kokufakwa kwezakhi zomzimba emathunjini).
- Uma izindlela zokuxilonga zensimbi zikhombisa izinguquko zesakhiwo esisitho sangaphakathi.
- Lapho kukhona isici sofuzo kuma-organ pathologies.
- Ukuhlolwa kokuvimbela.
Ngaphezu kwalokho, ezinye izifundo zingabekwa, isibonelo, ukuhlolwa kwegazi, i-ultrasound, i-compact tomography yezitho zesisu. Lokhu kuyadingeka ukuze kungafakwa eceleni i-pathologies okungenzeka yezinye izitho zangaphakathi nezinhlelo, ukucacisa pathogenesis yezinqubo ze-pathological emzimbeni. Imiphumela yokuhlolwa iyacutshungulwa kucatshangelwa izimpawu, ubude be-pathology, ukuhlangana kwezifo.
Ama-hormone akhiqizwa ama-pancreas athinta zonke izici zomzimba womuntu. Kumele babambe iqhaza ezinqubweni eziningi ukuze kugcinwe ukusebenza okujwayelekile kwezitho nezinhlelo. Yonke into emzimbeni ixhumekile, ngakho-ke amanye ama-hormone nawo abalulekile.
I-Thyroxin ikhiqizwa i-yegland gland. Kuthinta izinkomba zokucindezela kwegazi lomuntu, kufaka isandla ekunyukeni kwalo. I-physiology, amandla, ukuhamba nokuhamba kuncike ekuhlakazweni kwento esegazini. Ukushoda kuholela ekukhuluphelweni ngokweqile, ukukhathala okungapheli, izinwele kanye namazipho, umfutho wegazi ophansi nezinye izimpawu. Ukuze uthole ukwelashwa, i-pharmacology inikeza izidakamizwa zokwenziwa ezibandakanya i-thyroxine yokwenziwa.
I-adrenaline ye-hormone ikhiqizwa kwizindlala ze-adrenal. Ngokweqile kwendaba, umthelela usesimweni sengqondo nangokomzimba. Ngokwanda kokuhlushwa, umfutho wegazi uyakhuphuka, okuzoba yingozi enkulu yokuhlaselwa yisifo senhliziyo uma kunomlando wezinkinga ngohlelo lwenhliziyo; okuqukethwe ushukela emzimbeni kwehla kakhulu.
Ama-Hormones ahlanganiswe ama-pancreas ayadingeka ukuze kusebenze ukusebenza okujwayelekile komzimba. Uma kunokuntuleka noma ngokweqile, khona-ke ukulungiswa kwezinga lezinto ngosizo lwemithi kanye nokudla kuyadingeka.
Imininingwane ngama-pancreatic hormone inikezwe kuvidiyo kule ndatshana.
