I-Thioctacid ingenye yemithi, isakhi esiyinhloko sayo i-lipoic acid. Le ngxenye iyinto ebaluleke kakhulu emzimbeni womuntu futhi ingeyoqembu lezidakamizwa elinomphumela onenzuzo ku-normalization kanye nasezimisweni zezinqubo ze-metabolic, ikakhulukazi kumafutha kanye ne-carbohydrate.
I-Thioctacid yezidakamizwa iyi-Vitamin N, engabuya nokudla noma ikhiqizwe ngamasu afanele emzimbeni womuntu. Amanye amagama wengxenye enjalo ayaziwa. Lokhu kuqala, i-lipoic acid, i-thioctic acid, i-alpha lipoic acid. Akunandaba negama, izakhiwo eziyisisekelo zale ngxenye aziguquki.
Namuhla, amalungiselelo asuselwa ku-Vitamin N asetshenziswa ngenkuthalo ekwelashweni okuyinkimbinkimbi kwezifo ezahlukahlukene, kanye nasekuvimbeleni ukuthuthukiswa kwe-pathologies. Umuthi i-Thioctacid uthathwa abesifazane abafuna ukunciphisa umzimba kanye nabasubathi abachitha amandla amaningi ezifundweni zokuzivocavoca.
Ngenxa yokuthi ukukhiqizwa kwe-lipoic acid ngomzimba ngokwako kwenzeka ngamanani amancane amancane (anciphisa kakhulu ngobudala), kungenzeka ukuthi ubuyise ukuntuleka kwe-Vitamin ngosizo lwemithi ehlukahlukene kanye nemithako yokudla. Enye yale mithi amaphilisi kaTioctocide.
Umuthi unaziphi izindawo?
I-Thioctacid hr iyisidakamizwa se-metabolic, isithako esiyisisekelo esisebenzayo sayo i-alpha lipoic acid.
Le nto iqukethe emzimbeni womuntu ukugcina umsebenzi we-coenzyme ku-phosphorylation ye-oxidative ye-pyruvic acid ne-alpha-keto acid.
Ngokwakhiwa kwayo, i-thioctic acid iwuhlobo lwe-antioxidant endolo, oluthi ngomshini wezinto eziphilayo, lunokufana ngamavithamini we-B.
Izinga elidingekayo le-thioctic acid emzimbeni womuntu linikeza ukubopha kwama-radicals mahhala, asabalalisa imiphumela yawo enobuthi ezithweni zangaphakathi, asiza ukulawula amazinga eglucose egazini, futhi futhi andise izinga le-glycogen esibindini.
Ukusetshenziswa okuqhubekayo kwesidakamizwa ukuvimbela kunemiphumela elandelayo emzimbeni womuntu:
- ibuyisela phansi ukungafunwa kanye nomthelela omubi wezinto ezinobuthi, njengosawoti wezinsimbi ezisindayo kanye nobuthi,
- ine-hepatoprotective and detoxification izakhiwo,
- umphumela omuhle empilweni yesibindi, evumela ukusetshenziswa komuthi kwezifo ezahlukahlukene zesitho,
- uma kuthathwa ndawonye nge-ascorbic acid ne-vithamini E, ama-radicals mahhala awathathisiwe,
- isiza ukunciphisa i-lipids ne-cholesterol embi,
- kwandisa ukusetshenziswa kwe-glucose egazini,
- kuthinta kahle ukusebenza kohlelo lwezinzwa,
- uphatha imisebenzi yokuvikela ephathelene nemiphumela emibi yemisebe ye-ultraviolet,
- Iqhaza elisebenzayo ekuphatheni indlala yegilo,
- inyusa inani lamaprotheni akhiqizwayo
- lowers fatty acids
- inomphumela we-choleretic,
- esakhiweni sayo iyi-antispasmodic yemvelo,
- ivumela kahle ukwehla kwamandla kweprotheni e-glycolised,
- kunciphisa ingozi yokufa yindlala komoya-mpilo wamangqamuzana omzimba.
Ngaphezu kwalokho, abesifazane beminyaka ehlukene bavame ukukuthakasela lesi sidakamizwa, ngoba i-thioctic acid esilinganisweni esifanele iba nomphumela olandelayo emzimbeni:
- Ikusheshisa imetabolism futhi inciphisa iphango, ekuvumela ukuthi uyisebenzise njengendlela yokulawula isisindo.
- Kuthuthukisa isimo sesikhumba (ukukhulisa ukuqina kwaso nokunciphisa imibimbi emincane), izinwele nezinzipho.
- Umzimba uhlanjululwa ngokwemvelo ubuthi namathathi.
- Inomphumela wokuvuselela.
Ngokusekelwe ku-thioctic acid, imikhiqizo eminingi yokunakekelwa kwesikhumba yezimonyo ivame ukukhiqizwa.
I-Thioctacid iyisidakamizwa, ngakho-ke, ukuphathwa kwayo kufanele kwenziwe njengoba kushiwo udokotela oholayo.
Izinkomba zokusetshenziswa kwomuthi
Imiyalo yokusebenzisa i-Thioctocide ikhombisa ukusetshenziswa okuhlukahlukene kwalo muthi.
Ukuqokwa kwalo muthi kwenziwa ngudokotela ohambelayo.
Njengomphumela wokuthatha umuthi, i-alpha-lipoic acid idonswa ngokushesha yizitho zepheshana lesisu.
Izinkomba eziphambili zokusebenzisa umuthi yilezi ezilandelayo:
- ekwelashweni okuyinkimbinkimbi kokukhula kwezifo ezahlukahlukene zesibindi kanye nephephabhuku i-biliary (i-hepatitis engamahlalakhona, i-cirrhosis nesibindi fibrosis)
- isifo sokuqina kwemithambo yegazi nezinye izifo ezisetshenziselwa ukuqina kwamathambo, amaphilisi angaba yingxenye eyengeziwe ekwelapheni isifo sikashukela ukuze aqede ubungozi bokuthola ubunzima besistimu yenhliziyo,
- ngokwakhiwa kwezimbila ezahlukahlukene, okulimazayo nokulimazayo,
- ngokukhula komfutho wegazi ophakeme kanye nomfutho wegazi ophakeme,
- ukuqeda ukudakwa okuhlukahlukene kokutheleleka kanye nokunye komzimba,
- ngokwakhiwa kwe-polyneuropathy yesifo sikashukela noma yotshwala,
- uma kunokuphazamiseka ekuzwelweni kwamaphethelo aphansi ezinhlobo ezahlukahlukene,
- ukuvuselela ubuchopho kanye nokugcina i-acuity ebonakalayo,
- njengesinyathelo sokuvimbela ukwenza ngcono ukusebenza kwe-yegilo yegilo,
- ngokuvela kwe-neuropathy noma i-polyneuropathy, ikakhulukazi ephakama ngesikhathi sokudakwa okungapheli,
- ngesikhathi sokushaywa unhlangothi noma ukuhlaselwa yisifo senhliziyo,
- ngokwakhiwa kwe-Parkinson's pathology,
- uma kwenzeka isifo sikashukela i-retinopathy noma i-macular edema iba khona.
Ngaphezu kwalokho, i-Thioctacid b isetshenziswa kaningi ekwakhiweni komzimba, njengenye yezakhi zokwelashwa kokulungiswa. Indlela yakhe isuselwa ekwakhekeni kwama-radicals mahhala aqhamuka ngenxa yokuzivocavoca okukhulu komzimba. Ukuqeda le nqubo, lesi sidakamizwa siyasetshenziswa. Ngaphezu kwalokho, ukuthatha i-alpha-lipoic acid kuvumela abasubathi ukufezekisa:
- Ukulawulwa okujwayelekile kwesilinganiso esifanele se-lipids namaprotheni.
- Khulisa ukukhula kwemisipha.
- Nikeza indawo edingekayo yamandla futhi ululame ngokushesha ngemuva kokuqeqeshwa okusebenzayo.
- Gcina i-glycogen isesimweni esidingekayo.
Ukusetshenziswa okwengeziwe kwe-alpha lipoic acid kukhulisa ukuthathwa kwe-glucose kumaseli nezicubu zezitho zangaphakathi.
Imiyalo yokusebenzisa umuthi
Igama le-Thioctacid (mnn) elenziwa umhlaba wonke yi-thioctic acid, etholakala ngezindlela ezahlukahlukene - ngesimo sethebhulethi, emaphaketheni, kuma-ampoules wokujova okuphakathi kanye nokwehla.
Izwe lingumenzi womkhiqizi we-Thioctacid - iJalimane, inkampani yezokwelapha. Ukuqanjwa kwayo kususelwa kwisithako esiyisisekelo esisebenzayo nakwabathize abahlukahlukene. Kumele kuqashelwe ukuthi kwithebhulethi elilodwa lomuthi kukhona ama-600 mg ento esebenzayo. Ngaso leso sikhathi, umthamo ofanayo we-thioctic acid ngokufakwa kwamanzi okuhlanziwe kanye ne-trometamol ufakwa kwisisombululo se-thioctacid ukuze unikeze imijovo.
Umthamo wokwelapha ubekwa ngudokotela wezokwelapha ngokuya ngezinhloso zokwelashwa nalesi sifo. Njengomthetho, ukulungiswa kwethebhulethi kuchazwe ngenani lethebhulethi elilodwa, okumele lithathwe ekuseni (okungukuthi, kanye ngosuku). Umuthi ofanele kufanele uvele ngaphambi kobusuku bokudla kwasekuseni, cishe imizuzu engamashumi amathathu. Ekwelapheni i-neuropathy yesifo sikashukela, kusetshenziswa umthamo we-300 mg (isigamu sethebhulethi). Kulokhu, umthamo omkhulu wansuku zonke akufanele udlule ku-600 mg wento esebenzayo.
Uma udokotela ohambile enikeze umjovo wokungena ngalo muthi, khona-ke umthamo osetshenzisiwe uvame ukufuthwa ngamakhilogremu angamakhulu ayisithupha ento (i-ampoule eyodwa) kanye ngosuku. Inkambo yokwelashwa ingaba emasontweni amabili kuya kwamane.
Ngaphezu kwalokho, lesi sidakamizwa singasetshenziswa ukusetha i-dropper. Inqubo akufanele idlule isigamu sehora, futhi ukwethulwa kwalo muthi uqobo kufanele kusethelwe enkombeni encane - akukho okushesha okungaphezu kwamamililitha amabili ngomzuzu. Izinkomba zokusebenzisa ama-droppers kufanele zisungulwe ngudokotela ohambelayo.
Contraindication kanye nemiphumela emibi evela ekusebenziseni umuthi?
I-Thioctacid isidakamizwa i-Vitit N esikhiqizwa ngamanani amancane ngumzimba womuntu.
Kulesi simo, ukungahambisani nezincomo zezokwelapha noma i-overdose kungaholela ekubonisweni okuhlukahlukene okungalungile.
Ngaphezu kwalokho, kunezimo lapho ukusetshenziswa kwalesi sidakamizwa kunganconywa futhi kungavunyelwe.
Okokuqala, umuthi awusetshenziselwa ukwelapha:
- izingane nentsha
- ngesikhathi sokukhulelwa noma sokuxishwa,
- phambi kokungabekezelelani ngakunye kwezidakamizwa, izinto eziyinhloko noma ezisizayo,
- ngokungabekezeleli kwe-lactose kumuntu noma inani elanele le-lactase,
- ngokuthuthukiswa kwe-glucose-galactose malabsorption.
Ukuthatha i-Thioctacid, kufanele wenqabe ukuthatha imikhiqizo yobisi nobisi olunoshukela ngasikhathi sinye (umehluko phakathi kwemithamo kufanele okungenani kube ngamahora amabili), imithi equkethe izinsimbi.
Imiphumela emiphumela emqoka engahle yenzeke lapho uphuza umuthi yilena elandelayo:
- Eziswini zepheshana lesisu kanye nesistimu yokugaya ukudla - isicanucanu ngokuhlanza, ukushaya ngamandla kwenhliziyo, isifo sohudo, izinhlungu esiswini.
- Engxenyeni yezitho zesistimu yezinzwa, kungenzeka kuguquke izinguquko ekunambeni kwemizwa.
- Engxenyeni yezinqubo ze-metabolic ezenzeka emzimbeni - yehlisa ushukela wegazi ngaphansi kwesejwayelekile, isiyezi, ukujuluka okunyukayo, ukungasebenzi kahle kwesibonakaliso sikashukela.
- Ukuthuthukiswa kokungezwani komzimba ngesimo se-urticaria, ukuqubuka esikhunjeni, ukulunywa.
Ngokukhuphuka okukhulu kwemithamo enconyiwe, kungaqalwa imithi okweqisayo yemithi, ebonakala ngendlela yezimpawu ezilandelayo:
- imilenze emincane
- ukuphazamiseka kwegazi
- ukuthuthukiswa kwe-lactic acidosis,
- hypoglycemia
Njengokwelashwa, i-gastric lavage, ukuphathwa kwemithi ye-enterosorbent kanye nokwelashwa okubonakalayo kuyenziwa.
Imiphi imishanguzo engingangena esikhundleni somuthi ngayo?
Ukulungiswa kwethebhulethi iThioctacid imele i-alpha lipoic acid (analog ye-thioctic acid), ekhiqizwa ngumenzi wangaphandle. Intengo yomuthi esefomini yethebhulethi icishe ibe ngama-ruble ayi-1,500, kuyilapho iphakethe linamathebulethi angama-30 kumthamo ka-600 mg wento esebenzayo. Izindleko zemithi zokujova ngokungena ziyehluka kusuka ku-1,500 ziye kuma-ruble ayi-1,600 (ama-ampoules amahlanu).
Kuze kube manje, imakethe ye-pharmacological inikeza izifinyezo namagama ahlukahlukene we-Thioctacid, ahlukile ngesimo sokukhishwa, umthamo, izindleko kanye nenkampani yokukhiqiza.
I-Thiogamma isidakamizwa, isakhi esiyinhloko esisebenzayo sayo yi-thioctic acid. Ikhiqizwa yinkampani yezokwelapha yaseJalimane esefomini yethebhulethi, ngendlela yezisombululo zemijovo kanye ne-droppers. Inani lezithako ezisebenzayo ekwakhiweni lingama-600 mg. Inenombolo enkulu yokuphikisana ngokuqhathaniswa ne-thioctacid. Izindleko zamathebulethi ziyehluka kusuka kuma-ruble angama-800 kuye kwangama-1000.
Umkhiqizo wethebhulethi i-Berlition ungalethwa emakethe ngemithamo emibili - 300 noma u-600 mg wento esebenzayo - i-lipoic acid. Kutholakala ngesimo samathebulethi, amakhompiyutha noma ama-ampoules omjovo we-intramuscular. Inenombolo encane ye-contraindication kanye nengozi ephansi yokuphendula okuphambene. Amacwecwe angamashumi amathathu wesidakamizwa esinjalo anentengo esifundeni sama-ruble ayi-1000.
Izinzuzo ze-thioctic acid kusifo sikashukela zichazwe kuvidiyo kule ndatshana.
