Cishe i-90% yeziguli ezinesifo sikashukela zinesifo sohlobo lwesibili. Isiguli, ukuze siphile ngokugcwele, kumele sisebenzise izidakamizwa ze-hypoglycemic. I-Diabeteson MB umuthi osebenza ngempumelelo osehlisa izinga likashukela egazini kwisifo sikashukela.
Njengoba ukwelashwa ngezidakamizwa kudlala indima ebalulekile ekwelapheni "ukugula okumnandi", isiguli kumele sazi imininingwane ephelele mayelana nomuthi we-hypoglycemic awuphuzayo. Ukuze wenze lokhu, udinga ukufunda incazelo yomuthi emiyalweni enamathiselwe noma kwi-Intanethi.
Kepha kwesinye isikhathi kunzima ukuthola ukuthi ungubani. Le ndatshana izokusiza ukuthi ufunde ukuthi ungawuthatha kanjani umuthi, ukungqubuzana kwawo nemiphumela emibi engahle ibukewe, ukubuyekezwa kwamakhasimende, amanani entengo kanye nokufana kwawo.
Imininingwane yemithi ejwayelekile
I-Diabeteson MV ingukuphuma kwesizukulwane sesibili sulfonylurea. Kulokhu, isifinyezo se-MV sisho ukuthi amaphilisi wokukhishwa aguquliwe. Indlela yabo yokwenza imi ngolu hlobo: ithebhulethi, ewela esiswini sesiguli, inyibilika kungakapheli amahora amathathu. Ngemuva kwalokho umuthi usegazini futhi wehlise kancane izinga le-glucose. Ucwaningo luye lwabonisa ukuthi umuthi wanamuhla awuvamisile ukudala isimo se-hypoglycemia bese kuthi kamuva kube nezimpawu ezinkulu. Ngokuyisisekelo, umuthi uvame ukubekezelelwa iziguli eziningi. Izibalo zithi kuphela i-1% yamacala okuphendula okungalungile.
Isithako esisebenzayo - i-gliclazide inomphumela omuhle kumaseli we-beta akhiwe kumanyikwe. Ngenxa yalokho, baqala ukukhiqiza i-insulin ethe xaxa, i-hormone eyehlisa ushukela. Futhi, ngesikhathi sokusebenzisa umuthi, amathuba we-thrombosis emincane yegazi ancishisiwe. Ama-molecule wezidakamizwa anezinto ezingama-antioxidant.
Ngaphezu kwalokho, umuthi uqukethe izinto ezengeziwe ezinjenge-calcium hydrogen phosphate dihydrate, hypromellose 100 CP ne-4000 CP, maltodextrin, magnesium stearate ne-anhydrous colloidal silicon dioxide.
Kusetshenziswa amaphilisi e-diabeteson mb ekwelapheni isifo sikashukela sohlobo 2, lapho ezemidlalo kanye nokulandela indlela ekhethekile yokudla kungathinti i-glucose. Ngaphezu kwalokho, umuthi usetshenziswa ekuvinjelweni kwezinkinga ze- "sifo esimnandi" njenge:
- Izinkinga ze-Microvascular - nephropathy (ukulimala kwezinso) kanye ne-retinopathy (ukuvuvukala kwe-retina yezindlebe zamehlo).
- Izinkinga zeMacrovascular - stroke noma infarction ye-myocardial.
Kulokhu, umuthi awuthathwa njalo njengezindlela eziphambili zokwelapha. Imvamisa ekwelashweni kwesifo sikashukela sohlobo 2, sisetshenziselwa ukwelashwa iMetformin. Isiguli esiphuza umuthi kanye ngosuku singaba nokuqukethwe okusebenzayo kwento esebenzayo amahora angama-24.
I-Gliclazide idlulwa kakhulu yizinso ngendlela yama-metabolites.
Imiyalo yokusebenzisa amaphilisi
Ngaphambi kokwelashwa kwezidakamizwa, kufanele nakanjani uye lapho udibana khona nodokotela ozohlola isimo sempilo sesiguli futhi akunikeze ukwelashwa okusebenzayo ngemithamo efanele. Ngemuva kokuthenga i-Diabeteson MV, imiyalo yokusebenzisa kufanele ifundwe ngokucophelela ukugwema ukusetshenziswa kabi kwomuthi. Iphakethe lelo linamathebhulethi angama-30 noma angama-60. Ithebhulethi elilodwa liqukethe ama-30 noma ama-60 mg wezithako ezisebenzayo.
Endabeni yamaphilisi we-60 mg, umthamo wabantu abadala nabadala ekuqaleni ungama-0,5 amaphilisi ngosuku (30 mg). Uma izinga loshukela lincipha kancane, umthamo ungakhuphuka, kepha hhayi kaningi ukwedlula emva kwamaviki angama-2. Ukudla okuphezulu kwesidakamizwa ngamathebhulethi ayi-1.5-2 (90 mg noma i-120 mg). Idatha yedosi yireferensi kuphela. Udokotela oholayo kuphela, ebheka izici zesiguli kanye nemiphumela yokuhlaziywa kwe-glycated hemoglobin, ushukela egazini, ozokwazi ukunquma imithamo edingekayo.
Umuthi i-Diabeteson mb kumele usetshenziswe ngokunakekelwa okukhethekile kwiziguli ezinesifo sezinso kanye ne-hepatic, kanye nokudla okungajwayelekile. Ukuhambisana kwesidakamizwa neminye imithi kuphezulu impela. Isibonelo, i-Diabeteson mb ingathathwa ne-insulin, i-alpha glucosidase inhibitors kanye ne-biguanidines. Kepha ngokusebenzisa kanyekanye i-chlorpropamide, ukuthuthukiswa kwe-hypoglycemia kungenzeka. Ngakho-ke, ukwelashwa ngalezi zibhebhe kufanele kube ngaphansi kokuqashwa ngudokotela okuqinile.
Amacwecwe I-Diabeteson mb idinga ukufihlwa isikhathi eside emehlweni wezingane. Impilo yeshelf iyiminyaka emi-2.
Ngemuva kwalesi sikhathi, ukusetshenziswa komuthi akuvunyelwe ngokuphelele.
Contraindication kanye nemiphumela emibi
Njengamanye ama-sulfonylurea avela, umuthi i-Diabeteson MR unohlu olukhulu kakhulu lwe-contraindication. Kufaka:
- Ukuba khona kohlobo 1 sikashukela.
- I-ketoacidosis kushukela - ukwephulwa emzimbeni we-carbohydrate.
- Isimo se-precoma, i-hypersmolar noma i-ketoacidotic coma.
- Isifo sikashukela esincanyana nesinciphile.
- Ukuphazamiseka emsebenzini wezinso, isibindi, ezimweni ezinzima - ukuhluleka kwezinso kanye nesibindi.
- Ukusetshenziswa okufanayo kwe-miconazole.
- Isikhathi sokukhulelwa nokuqunjelwa.
- Izingane ezingaphansi kweminyaka engu-18.
- Ukungabekezelelani komuntu ngamunye ku-gliclazide nezinye izinto eziqukethwe kulungiselelo.
Ngokunakekelwa okukhethekile, udokotela unquma i-Diabeteson MR ezigulini ezihlushwa:
- i-pathologies yesistimu yenhliziyo - ukushaya kwenhliziyo, ukuhluleka kwenhliziyo, njll.
- I-hypothyroidism - ukwehla kwamanyikwe;
- ukunganele kwe-pituitary noma i-adrenal gland;
- umsebenzi wokuphazamiseka kwezinso nesibindi, ikakhulukazi isifo sikashukela;
- uphuzo oludakayo.
Ngaphezu kwalokho, lesi sidakamizwa sisetshenziswa ngokuqapha ezigulini esezikhulile nasezigulini ezingalandeli ukudla okujwayelekile nokunempilo. I-overdose ingaholela emiphumeleni ehlukahlukene yomuthi Diabeteson MR:
- I-Hypoglycemia - ukwehla ngokushesha ushukela wegazi. Izimpawu zalesi simo zithathwa njengekhanda, ukozela, ukwethuka, ukulala kabi nobuthongo obukhulu, ukukhuphuka kwenhliziyo. Nge-hypoglycemia encane, ingamiswa ekhaya, kepha ezimweni ezinzima, ukunakekelwa kwezokwelapha okuphuthumayo kuyadingeka.
- Ukuphazamiseka kwesistimu yokugaya ukudla. Izimpawu eziphambili ubuhlungu besisu, isicanucanu, ukugabha, ukuqunjelwa noma isifo sohudo.
- Ukusabela okuhlukahlukene kokungezwani komzimba - ukuqhuma kwesikhumba nokulunywa.
- Ukwanda komsebenzi we-enzyme yesibindi njenge-ALT, AST, phosphatase ye-alkaline.
- Ezimweni ezingavamile, ukuthuthukiswa kwe-hepatitis kanye ne-jaundice.
- Ukuguqulwa okungathandeki kokuqanjwa kwe-plasma yegazi.
Ukusetshenziswa kwesidakamizwa nakho kungaholela ekulimazelweni okubukwayo ekuqaleni kokuthatha amaphilisi ngenxa yokwehla ushukela okusheshayo, bese iyaqala kabusha.
Ukubuyekezwa kwezindleko nezidakamizwa
Ungathenga i-MR Diabeteson ekhemisi noma ufake i-oda online kwiwebhusayithi yomthengisi. Njengoba amazwe amaningi akhiqiza umuthi we-Diabeteson MV ngasikhathi sinye, intengo ekhemisi ingahluka kakhulu. Izindleko ezijwayelekile zomuthi zingama-ruble angama-300 (ama-60 mg lilinye, amaphilisi angama-30) nama-ruble angama-290 (ama-30 mg ngalinye izingcezu ezingama-60). Ngaphezu kwalokho, ibanga lezindleko liyahluka:
- I-60 mg amaphilisi wezingcezu ezingama-30: ubuningi bama-ruble angama-334, ubuncane bama-ruble angama-276.
- Amacwecwe ama-30 mg wezingcezu ezingama-60: ubuningi bama-ruble angama-293, ubuncane bama-ruble angama-287.
Kungaphethwa ngokuthi lesi sidakamizwa asibizi kakhulu futhi singathengwa ngabantu abahola imali ephakathi abanesifo sikashukela sohlobo 2. Umuthi uqokwa ngokuya ngokuthi imiphi imithamo ebekwe udokotela oya kuye.
Ukubuyekezwa mayelana noDiabeteson MV kulungile. Ngempela, inani elikhulu leziguli ezinesifo sikashukela zithi umuthi wehlisela amazinga eglucose kumanani ajwayelekile. Ngaphezu kwalokho, lo muthi ungaqokomisa izici ezinjalo ezinhle:
- Ithuba eliphansi kakhulu le-hypoglycemia (hhayi ngaphezu kwama-7%).
- Umthamo owodwa womuthi ngosuku wenza impilo yeziguli eziningi ibe lula.
- Ngenxa yokusetshenziswa kwe-MV gliclazide, iziguli azitholi ukwanda okusheshayo kwesisindo somzimba. Amaphawundi ambalwa nje, kepha akusekho okunye.
Kodwa futhi kukhona nokubuyekezwa okungalungile mayelana nomuthi Diabeteson MV, ovame ukuhlotshaniswa nezimo ezinjalo:
- Abantu abancane babe nezimo zokuthuthuka kwesifo sikashukela esincike ku-insulin.
- Uhlobo 2 sikashukela lungangena ohlotsheni lokuqala lwesifo.
- Umuthi awulwi ne-insulin resistance syndrome.
Ucwaningo lwakamuva luveze ukuthi umuthi i-Diabeteson MR awukwehlisi inani labantu ababulawa yisifo sikashukela.
Ngaphezu kwalokho, kuthinta kabi amaseli e-pancreatic B, kepha ama-endocrinologists amaningi awayinaki le nkinga.
Izidakamizwa ezifanayo
Njengoba isidakamizwa i-Diabeteson MB sinokuphikisana okuningi nemiphumela emibi, kwesinye isikhathi ukusetshenziswa kwaso kungaba yingozi esigulini esinesifo sikashukela.
Kulokhu, udokotela uguqula irejimithi yokwelashwa futhi anikeze elinye ikhambi, umphumela wokwelapha wawo ofana noDiabeteson MV. Kungaba:
- I-Onglisa iyi-hypoglycemic ephumelelayo yesifo sikashukela sohlobo 2. Ngokuyisisekelo, ithathwa ihlanganiswe nezinye izinto ezinjenge-metformin, pioglitazone, glibenclamide, dithiazem nabanye. Ayinakho ukusabela okungathi sína okungaka njengoDiabeteson mb. Intengo emaphakathi ama-ruble ayi-1950.
- I-Glucophage 850 - isidakamizwa esine-metformin esebenzayo yesithako. Ngesikhathi sokwelashwa, iziguli eziningi ziphawule ukuthi ukuqina kweshukela egxilile kuhlala isikhathi eside, kanye nokwehla kwesisindo ngokweqile. Kwehlisa amathuba okufa kwesifo sikashukela ngesigamu, kanye namathuba okushaya kwenhliziyo nokushaywa unhlangothi. Intengo ephakathi ingama-ruble angama-235.
- I-Altar isidakamizwa esiqukethe i-izidakamizwa i-glimepiride, ekhipha i-insulin ngamaseli e-pancreatic B. Kuliqiniso, umuthi uqukethe imibango eminingi. Izindleko ezijwayelekile ama-ruble angama-749.
- I-Diagnizide iqukethe ingxenye esemqoka ehlobene nokususelwa kwe-sulfonylurea. Umuthi awuthathwe ngokudakwa okungapheli, i-phenylbutazone kanye ne-danazole. Umuthi unciphisa ukumelana ne-insulin. Intengo emaphakathi ama-ruble angama-278.
- I-Siofor i-ejenti enhle kakhulu ye-hypoglycemic. Ingasetshenziswa ngokuhlanganiswa nezinye izidakamizwa, isibonelo, i-salicylate, i-sulfonylurea, i-insulin nezinye. Izindleko ezijwayelekile ngama-ruble angama-423.
- IManinil isetshenziselwa ukuvikela izimo ze-hypoglycemic kanye nasekwelapheni isifo sikashukela sohlobo 2. NjengoDiabeteson 90 mg, inenani elikhulu kakhulu le-contraindication nemiphumela emibi. Intengo ephakathi yesidakamizwa ama-ruble ayi-159.
- IGlybomet inomphumela omuhle emzimbeni wesiguli, ivuselela ukucasulwa kwe-insulin. Izinto eziyinhloko zalo muthi yi-metformin ne-glibenclamide. Intengo ephakathi yesidakamizwa ama-ruble angama-314.
Lolu akulona uhla oluphelele lwezidakamizwa ezifana ne-Diabeteson mb. IGlidiab MV, Gliclazide MV, Diabefarm MV zithathwa njengezivumelwano zalo muthi. Udokotela onesifo sikashukela nodokotela wakhe ohambele kufanele akhethe indawo yesifo sikashukela ngokususelwa kumphumela olindelekile wokwelapha namandla emali esiguli.
I-Diabeteson mb isidakamizwa esisebenzayo se-hypoglycemic esinciphisa ukugcwala kweglucose egazini. Iziguli eziningi zisabela kahle kulo muthi. Okwamanje, inezici ezimbili ezinhle nokubi okuthile. Ukwelashwa ngezidakamizwa kungenye yezindlela zokwelashwa okuphumelela kohlobo lweshukela sikashukela. Kodwa ungakhohlwa ngokudla okufanele, ukusebenza komzimba, ukulawula ushukela wegazi, ukuphumula okuhle.
Ukwehluleka ukuthobela okungenani iphoyinti elilodwa lokuphoqelela kungahle kwehluleke ekwelashweni kwezidakamizwa noDiabeteson MR. Isiguli asivunyelwe ukuzindla. Isiguli kufanele silalele udokotela, ngoba noma isiphi isibonakaliso saso singaba yisihluthulelo sokuxazulula inkinga yokuqukethwe okunoshukela ophezulu onesifo "esimnandi". Yiba nempilo!
Isazi kuvidiyo ekulesi sihloko sizokhuluma ngamathebulethi e-Diabeteson.
