I-humulin K25 100p insulin isidakamizwa esiyingxenye yeqembu lezidakamizwa ze-antidiabetes. Kutholakala ngesimo sokumiswa komjovo futhi kuyinhlanganisela yokufakwa komuntu kwesikhathi sokusebenza esiphakathi nesimfishane.
Ukuqanjwa kwesidakamizwa - 25% i-insulin enganyibiliki nama-insulin-isophan. Umuthi uxhumana ne-receptor ye-cytoplasmic cell membrane, enza i-insulin-receptor tata, ekhuthaza ukusebenza kwe-intracellular, kufaka phakathi ukwakheka kwama-enzymes ahlukahlukene.
Umuthi ubekelwe ukwelashwa kwesifo sikashukela sohlobo lwesibili nolokuqala, kanye nokumelana nemithi ye-hypoglycemic yomlomo. Futhi, umuthi unqunyiwe uma kukhona ama-pathologies wezinto ezihlobene kanye nokungenelela kokuhlinzwa. Ezimweni eziningi, ikhambi liboniswa ngesifo sikashukela, esakhula ngesikhathi sokukhulelwa. Endabeni yesibili, udokotela ubeka ikhambi ngokumelene nesizinda sokungasebenzi kahle kokulashwa kokudla.
Ikhemisi
I-Humodar K25-100 ilungiselelo le-insulin elenziwe elenziwa ngabantu lesikhathi eside lesenzo.
Umuthi uqukethe i-insulin - i-isophan ne-soluble insulin. Umuthi ukhuthaza ukuvela kwama-enzymes ahlukahlukene.
Phakathi kwezinto eziphambili:
- i-pyruvate kinase,
- hexokinase
- glycogen synthetase nabanye.
Isikhathi semiphumela yokulungiswa kwe-insulin kuvame ukunqunywa ngesilinganiso sokumuncwa. Kuya ngendawo yemijovo nemithamo, ngakho iphrofayili yesenzo se-insulin ingahluka kakhulu, futhi kubantu abahlukahlukene, nakwisiguli esisodwa.
Umuthi uqala ngemuva kokuphathwa ngokunqenqemeni, lokhu kwenzeka ngemuva kwengxenye yehora. Umphumela omkhulu kwenzeka, imvamisa emva kwamahora ambalwa. Isenzo sithatha amahora angama-12 kuye kwangama-17.
Imiyalo yokusebenzisa umuthi
Isikhathi semijovo nomthamo kusethwa udokotela kuphela esimweni ngasinye, kususelwa kulesimo ngezinqubo ze-metabolic. Lapho ukhetha imithamo ye-insulin yabantu abadala, udinga ukuqala ngesikhawu esisodwa samaayunithi ayi-8-24.
Ngokuzwela okuphezulu kwe-hormone nasebuntwaneni, kusetshenziswa imithamo engaphansi kwama-8 amayunithi. Uma ukuzwela kuncishisiwe, khona-ke umthamo osebenzayo ungaba ngaphezulu kwamayunithi angama-24. Umthamo owodwa akufanele ube ngaphezu kwamayunithi angama-40.
I-cartridge enezinto kufanele igoqwe cishe izikhathi eziyishumi phakathi kwezintende ngaphambi kokusetshenziswa futhi iguqulwe inani elifanayo lezikhathi. Ngaphambi kokufaka i-cartridge kwipeni yesirinji, kufanele uqiniseke ukuthi ukumiswa kukodwa, futhi uma kungenjalo, phinda inqubo futhi. Umuthi kumele ube ngokulinganayo u-milky noma ube ngamafu ngemuva kokuxubana.
I-Humodar P K25 100 kufanele iphathwe cishe imizuzu engama-35-45 ngaphambi kokudla ngokungena noma ngokuxinana. Indawo yomjovo iyashintsha ngomjovo ngamunye.
Ukushintshela kwamanye amalungiselelo e-insulin kwenziwa kuphela ngaphansi kokuqashwa ngudokotela. Isiguli kufanele sinamathele ngokuqinile ku:
- ukudla
- imithamo nsuku zonke ye-insulin,
- ivolumu yokusebenza komzimba.
Isu lokusebenzisa imijovo lapho usebenzisa i-insulin ezimpondweni
I-Cartridge eneHumodar K25-100 isetshenziselwa isetshenziswa emapeni wesirinji. Ngaphambi kokusebenzisa, qiniseka ukuthi i-cartridge ayilimalanga. Ngemuva kokuthi i-cartridge ifakwe esibayeni, umucu wemibala kufanele ubonakale.
Ngaphambi kokufaka i-cartridge esiphathweni, udinga ukuyivula bese uyibeka phansi ukuze ibhola yengilazi iqale ukungena ngaphakathi. Ngakho-ke, ukuxutshwa kwento. Le nqubo iyaphindwa kuze kube yilapho uketshezi luthole umbala omhlophe we-turbid. Ngemuva kwalokho umjovo wenziwa ngokushesha.
Ngemuva komjovo, inaliti kufanele ihlale esikhunjeni cishe imizuzwana emihlanu. Gcina inkinobho icindezelwe kuze kube yilapho inaliti isuswa ngokuphelele ngaphansi kwesikhumba. I-cartridge ingeyokuzisebenzisela wena kuphela futhi akufanele ifakwe kabusha.
Kukhona i-algorithm ethile yokwenza umjovo we-insulin:
- ukubulala amagciwane ulwelwesi werabha ebhodleleni,
- setha isirinji yomoya ngevolumu ehambelana nomthamo ofunekayo we-insulin. Umoya wethulwa ebhodleleni unento,
- ukuguqula ibhodlela nesirinji libheke phezulu bese usetha umthamo ofunekayo we-insulin esitokisini. Susa inaliti kusuka ku-vial bese ususa umoya ku-syringe. Bheka ukunemba kwesethi ye-insulin,
- umkhiqizo womjovo.
Ukweqisa komzimba nemiphumela emibi
Umuthi ungadala imiphumela emibi maqondana nomphumela wawo kuma-carbohydrate metabolism.
Ngakho-ke, kwezinye izimo izimo ze-hypoglycemic zenzeka.
Imvamisa, iziguli zingakhalaza:
- kaningi ukushaya kwenhliziyo
- indlala yesikhumba
- umjuluko osindayo
- migraines
- imilenze ethuthumela
- ukuguguleka ngokweqile
- indlala
- i-paresthesia endaweni yomlomo.
I-hypoglycemia enkulu ingaholela ekwakhekeni kwethonya elikhulu le-hypoglycemic. Ezimweni ezithile, umuntu angahlupheka:
- ukuqhuma kwesikhumba
- Idumela likaQuincke,
- ukwethuka kwe-anaphylactic.
Kungaba futhi:
- hyperemia,
- ukulunywa yi-pruritus nokuvuvukala,
- lipodystrophy.
Kuyaziwa futhi nokuphendula komzimba:
- ukuvuvukala okuhlukahlukene
- ukuphazamiseka ngezikhathi ezithile kwezinkomba.
Uma kwenzeka kweqa ngokweqile, kungahle kube ne-hypoglycemia. Uma kwenzeka ngesimo esincane, isiguli singathatha ushukela noma ukudla ngama-carbohydrate. Abantu abanesifo sikashukela kudingeka baphathe njalo amaswidi, ushukela, noma ujusi omnandi wezithelo.
Uma sikhuluma ngezindlela ezinzima ze-hypoglycemia, umuntu ogulayo angalahlekelwa ukwazi. Kulokhu, isixazululo sikashukela esingu-40% kumele siphathwe ngokuqondile. Lapho ukwazi ukuvuselelwa kwengqondo kubuyiselwa, umuntu kufanele ngokushesha adle ukudla nama-carbohydrate ukuze isimo singabe sisakhula.
Ukusebenzelana kwezidakamizwa
Umuthi uxhumana nezidakamizwa ezingangezwa kuhlobo lokwelashwa.
Ukuthatha imishanguzo ethile kungenza buthaka noma kwandise umphumela we-insulin eglucose yegazi.
Ukuthuthuka komphumela wento kungabonakala ngokuqokwa kanyekanye:
- Mao inhibitors
- ama-beta-blockers angakhethi,
- Ama-anabolic steroid
- tetracycline
- sulfanamide
- shaya umoya
- fenfluramine,
- cyclophosphamide
- amalungiselelo aqukethe i-ethanol.
I-insulin ingawenza buthaka umphumela wayo ngenkathi usebenzisa:
- chlorprotixen,
- izindlela zokuvimbela inzalo
- ama-diuretics - ama-saluretics,
- heparin
- i-lithium carbonate
- corticosteroids
- diazoxide
- isoniazid
- i-nicotinic acid eluhlobo 2 sikashukela,
- ama-hormone egilo
- ama-audiathomimetic agents
- triddclic antidepressants.
Kubantu abathatha i-insulin, i-reserpine, i-clonidine ne-salicylates ngasikhathi sinye, kokubili ukukhuphuka kanye nokwehla komphumela we-insulin kungabonakala.
Ukuphuza uphuzo oludakayo nakho kuholela ekwehlekeni okukhulu kwamazinga kashukela egazini.
Ezinye izici
Ngokuphikisana nesizinda sokwelashwa kwe-insulin, ukuqapha ushukela wegazi njalo kuyadingeka. I-Hypoglycemia, ngaphezu kwe-insulin overdose, ingavela esikhundleni somuthi esingafanele.
I-Hypoglycemia yisimo esiyingozi, izimbangela zazo ezibuye zibhekwe:
- ukweqa ukudla
- ukusebenza ngokweqile komzimba
- ukugula okunciphisa isidingo se-insulin,
- ukuguqulwa kwendawo yomjovo.
Ukuthathwa okungalungile noma ukuphazamiseka kumijovo ye-insulin kungaholela ku-hyperglycemia. Imvamisa, ukubonakaliswa kwe-hyperglycemia kwakhiwa kancane, lokhu kudinga amahora noma izinsuku ezimbalwa.
I-Hyperglycemia iveziwe:
- ukoma
- ukuchama ngokweqile,
- ukugabha kanye nenausea
- isiyezi
- isikhumba esomile
- ukulahleka kwesifiso.
Umthamo we-insulin kufanele ulungiswe uma umsebenzi we-thyroid ukhubazekile, kanye:
- Isifo sika-Addison
- hypopituitarism,
- umsebenzi wokuphazamiseka kwezinso nesibindi,
- isifo sikashukela kubantu abangaphezu kweminyaka engama-65.
Ukushintsha umthamo kuyadingeka futhi uma isiguli sandisa umsebenzi waso womzimba, noma senza ushintsho ekudleni okujwayelekile.
Lapho usebenzisa umkhiqizo, amandla okushayela imoto noma elawula izindlela ezithile angancipha.
Ukugxila kokunakwa kuyancipha, ngakho-ke akunconywa ukwenza imisebenzi ehambisana nesidingo sokuphendula ngokushesha nokwenza izinqumo ezibalulekile.
Ama-Analog
Ama-analogs asetshenziswa izidakamizwa ezingase zibe yizindawo ezifanele kunazo zonke zeHumodar k25 100r.
Izinhlu zaleli thuluzi zinokwakheka okufanayo kwezinto futhi zifanisa indlela yokusebenzisa, kanye nemiyalo nezinkomba.
Phakathi kokufana okuthandwa kakhulu yilezi:
- Humulin M3,
- I-Ryzodeg Flextach,
- Umxube weHumalog,
- I-Insulin Gensulin N ne-M30,
- I-Novomax Flekspen,
- I-Farmasulin H 30/70.
Izindleko zomuthi uHumodar K25 100r ziyehluka ngokuya ngesifunda nendawo ekhemisi. Intengo ephakathi yesidakamizwa ama-3ml 5 ama-pcs. isukela ku-1890 kuya kuma-ruble angama-2100. Umuthi unezibuyekezo ezinhle kakhulu.
Mayelana nezinhlobo ze-insulin nezici zazo zizotshela ividiyo ekulesi sihloko.
