Ama-Lozap namaLorista alungiswa angama-analogues futhi angamalungu eqembu elilodwa lezemithi - angiotensin 2 receptor antagonists.
Ngaphandle kokuthi banesakhi esifanayo esisebenzayo, ukwakheka nokwenziwe ngentengo kuhlukile. Ukunquma ukuthi imuphi umuthi ongcono, udinga ukutadisha bese uqhathanisa yomibili imishanguzo.
Izakhiwo ze-Lozap
Ukukhishwa ifomu - amaphilisi. Umuthi ungathengwa emakhemisi wezingcezu ezingama-30, 60 nezingama-90 ngephakethe ngalinye. Isithako esikhulu esisebenzayo kuzo yi-losartan. Ithebhulethi eyi-1 ingaqukatha u-12,5, 50 no-100 mg. Ngaphezu kwalokho, kukhona amakhompiyutha asizayo.
Ama-Lozap namaLorista alungiswa angama-analogues futhi angamalungu eqembu elilodwa lezemithi - angiotensin 2 receptor antagonists.
Umphumela wesidakamizwa i-Lozap ihloselwe ukwehlisa umfutho wegazi. Ngaphezu kwalokho, umuthi unciphisa ukumelana okuphathelene ne-peripheral. Ngenxa yethuluzi, umthwalo osemisipha yenhliziyo nawo uyancishiswa. Amanzi amaningi nosawoti adonswa emzimbeni ngomchamo.
I-Lozap ivimbela ukuphazamiseka emsebenzini we-myocardium, i-hypertrophy yayo, ikhulisa ukukhuthazela kwenhliziyo nemithambo yegazi ekusebenzeni ngokomzimba ikakhulukazi kubantu abane-pathologies engapheli yalesi sitho.
Ukuphila kwesigamu kwengxenye esebenzayo kusuka emahoreni ayisithupha kuya kwayi-9. Cishe i-60% ye-metabolite esebenzayo ikhishwa kanye ne-bile, kanti konke okunye nomchamo.
Izinkomba zokusebenzisa iLozap zingokulandelayo:
- i-arterial hypertension;
- ukwehluleka kwenhliziyo okungapheli;
- Izinkinga zohlobo 2 sikashukela i-mellitus (nephropathy ngenxa ye-hypercreatininemia ne-proteinuria).
Ngaphezu kwalokho, umuthi ubekelwe ukunciphisa amathuba okukhula kwe-inhliziyo nethambo (kusebenza ku-stroke), kanye nokwehlisa izinga lokushona kwabantu abanomfutho wegazi ophakeme kanye ne-hypertrophy yenhliziyo.
Ukuxhumana kokusetshenziswa kweLozap yile:
- ukukhulelwa nokuqunjelwa;
- hypersensitivity kulo muthi nezakhi zawo.
Izingane ezingaphansi kweminyaka engu-18 nazo azifanele.
Ukuqapha kuyadingeka ukuthatha umuthi onjalo kubantu abalimele usawoti wamanzi, umfutho ophansi wegazi, i-vasen stenosis ezinso, izinso noma ukwehluleka kwezinso.
Ngabe uLorista usebenza kanjani?
Ifomu lokukhipha umuthi i-Lorista ngamathebulethi. Iphakheji eli-1 liqukethe izingcezu eziyi-14, 30, 60 noma ezingama-90. Isithako esikhulu esisebenzayo yi-losartan. Ithebhulethi eyi-1 iqukethe u-12,5, 25, 50, 100 no-150 mg.
Isenzo sikaLorista sihloselwe ukuvimba ama-receptors e-AT 2 esifundeni senhliziyo, i-vascular and renal. Ngenxa yalokhu, i-lumen of the artery, ukumelana kwabo kuncipha, izinga lokucindezela kwegazi liyancipha.
Izinkomba zokusetshenziswa zimi ngokulandelayo:
- umfutho wegazi ophakeme
- ukunciphisa ubungozi bokushaywa yi-hypertension kanye nokukhubazeka kwe-myocardial;
- ukwehluleka kwenhliziyo okungapheli;
- ukuvimbela izinkinga ezithinta izinso kuhlobo 2 lwesifo sikashukela nge-proteinuria eyengeziwe.
Contraindication ifaka:
- umfutho wegazi ophansi;
- ukomisa;
- ibhalansi yamanzi-kasawoti ephazamisekile;
- ukungabekezelelani kwe-lactose;
- ukwephulwa kwezinqubo zokufaka i-glucose;
- ukukhulelwa nokukhipha umunyu.
- hypersensitivity kulo muthi noma izakhi zawo.
Ezinganeni ezingaphansi kweminyaka eyi-18, lesi sidakamizwa naso asinconywa. Ukuqapha kufanele kunikezwe abantu abane-renal and hepatic insufficiency, i-stenosis yemithambo yezinso ezinso.
Ukuqhathaniswa kukaLozap noLorista
Ukunquma ukuthi yisiphi isidakamizwa - uLozap noma uLorista - osifanele isiguli, kuyadingeka ukuthola ukuthi ukufana kwazo nokuthi izidakamizwa zihluka kanjani.
Ukufana
ILozap neLorista banezinto eziningi ezifanayo, njengoba Yizichazi:
- yomibili le mithi ingeyeqembu le-angiotensin 2 receptor antagonists;
- babe nezinkomba ezifanayo zokusetshenziswa;
- aqukethe isithako esifanayo esisebenzayo - i-losartan;
- zombili izinketho zitholakala kwifomu lethebhulethi.
Ngokuqondene nomthamo wansuku zonke, khona-ke ama-50 mg ngosuku anele. Lo mthetho uyafana kuLozap noLorista, ngoba amalungiselelo aqukethe inani elilinganayo le-losartan. Zombili lezi zidakamizwa zingathengwa emakhemisi kuphela ngokuya kudokotela.
Imithi ibekezelelwa kahle, kepha kwesinye isikhathi izimpawu ezingafuneki zingavela. Imiphumela emibi ye-Lozap neLorista nayo iyafana:
- inkinga yokulala
- ikhanda, isiyezi;
- ukukhathala okungapheli;
- i-arrhythmia ne-tachycardia;
- Ubuhlungu besisu, isicanucanu, i-gastritis, uhudo;
- ukuqubuka kwamakhala, ukuvuvukala kwezingqimba ze-mucous emgodleni wamakhala;
- ukukhwehlela, i-bronchitis, pharyngitis.
Ngaphezu kwalokho, kufanele kukhunjulwe ukuthi amalungiselelo ahlanganisiwe ayatholakala - I-Lorista N ne-Lozap Plus. Zombili lezi zidakamizwa aziqukethe i-losartan kuphela njengesithako esisebenzayo, kodwa futhi nesinye isakhi - i-hydrochlorothiazide. Ukuba khona kwento enjalo yokusiza lapho kulungiswa kuboniswa egameni. KuLorista, le ngu-N, ND noma i-H100, futhi kuLozap, igama elithi "plus".
ILoapap Plus noLorista N yizifanekiselo zomunye nomunye. Womabili amalungiselelo aqukethe i-50 mg ye-losartan ne-12.5 mg ye-hydrochlorothiazide.
Ukulungiselela kohlobo oluhlanganisiwe kwenzelwe ukulawula ngokushesha izinqubo ezi-2 ezithinta umfutho wegazi. I-Losartan lowers vascular ithoni, ne-hydrochlorothiazide yakhelwe ukukhipha uketshezi oluningi emzimbeni.
Uyini umehluko?
Umehluko phakathi kweLozap neLorista awubalulekile:
- umthamo (I-Lozap inezinketho ezi-3 kuphela, futhi uLorista unezinketho eziningi - 5);
- Umkhiqizi (uLorista ukhiqizwa yinkampani yaseSlovenia, yize kukhona igatsha laseRussia - iKRKA-RUS, kanti iLozap ikhiqizwa yinhlangano yeSlovak Zentiva).
Naphezu kokusebenzisa isithako esiyisisekelo esifanayo, uhlu lwabazokuthola nalo luhlukile. Izakhi ezilandelayo zisetshenzisiwe:
- I-Cellactose Yethula kuphela kuLorist. Le khompiyutha itholakala ngesisekelo se-lactose monohydrate ne-cellulose. Kepha okwedlule kubuye ku-Lozap.
- Isitashi. Kukhona eLorist kuphela. Ngaphezu kwalokho, kunezinhlobo ezi-2 emthini owodwa - i-gelatinized kanye nesitashi sommbila.
- I-Crospovidone ne-mannitol. Iqukethwe eLozap, kepha ayikho eLorist.
Zonke ezinye izembatho zikaLorista neLozap ziyefana.
Yikuphi okushibhile?
Intengo yazo zombili izidakamizwa incike kwinani lamathebulethi kuphakethe kanye nomthamo wezinto eziphambili. Ungathenga i-Lorista ngama-ruble angama-390-480. Lokhu kusebenza ekufakweni kwamathebulethi angama-90 ngomthamo ongu-50 mg we-losartan. Ukupakishwa okufanayo kweLoapap kubiza ama-ruble ayi-660-780.
Yini engcono kuneLozap noma iLorista
Zombili lezi zidakamizwa ziyasebenza eqenjini labo. Into ye-losartan inezinzuzo ezilandelayo:
- Ukukhetha. Umuthi kuhloswe ngawo ukubopha kuphela nama-receptors adingekayo. Ngenxa yalokhu, azithinti ezinye izinhlelo zomzimba. Ngenxa yalokhu, zombili lezi zidakamizwa zithathwa njengephephe kunezinye izidakamizwa.
- Umsebenzi ophakeme lapho uthatha umuthi ngendlela yomlomo.
- Awukho umthelela ezinqubweni ze-metabolic zamafutha nama-carbohydrate, ngakho-ke zombili lezi zidakamizwa zivunyelwe kushukela.
ILosartan ithathwa njengenye yezinto zokuqala ezivela eqenjini lama-blockers, elivunyelwe ukwelashwa kwe-hypertension ngeminyaka yama-90s. Kuze kube manje, izidakamizwa esekwe kuzo zisetshenziselwa umfutho wegazi ophakeme.
Bobabili uLorista noLozzap bayimithi esebenzayo ngenxa yokuqukethwe kwe-losartan ekuhlushweni okufanayo. Kodwa lapho ukhetha umuthi, ama-contraindication nawo ayabhekwa.
I-Lorista ithathwa njengeyingozi kakhulu kubantu kuneLozap. Lokhu kungenxa yokuthi imiphumela emibi kungenzeka ivele. Ngaphezu kwalokho, umuthi onjalo wenqatshelwe kubantu abane-lactose ukungabekezeleli kanye nokungahambi kahle kwesitashi. Kepha ngasikhathi sinye, umuthi onjalo ushibhile.
I-Lorista ithathwa njengeyingozi kakhulu kubantu kuneLozap.
Ukubuyekezwa kweziguli
USvetlana: "Ngiqale ukusebenzisa umuthi kaLorista ekuncomeni kadokotela. Ezinye izidakamizwa azange zisize ngalutho. Manje umfutho wegazi wami wehlile, kodwa wahluleka khona lapho. Kwakune-tinnitus, yize yanyamalala ezinsukwini ezimbalwa."
U-Oleg: "Umama ubelokhu enomfutho wegazi ophakeme kusukela aneminyaka engu-27. Ngaphambi kwalokho, wasebenzisa izidakamizwa ezahlukahlukene, kepha manje azisizi ngalutho. Eminyakeni engu-2 edlule washintsha waya eLozap. Akusekho zinkinga."
Ukubuyekezwa okwenziwa ngabachwepheshe bezenhliziyo ngeLozap noma iLorista
UDanilov SG: "Eminyakeni eminingi yokuzilolonga, umuthi weLorista uzitholele wona. Kuyithuluzi elingabizi kepha kodwa elisebenzayo. Kuyasiza ukubhekana nomfutho wegazi ophakeme. Umuthi ulula ukuthatha, kunemiphumela emibi embalwa, futhi akuvamile ukwenzeka."
UZhikhareva EL: "ILozap isidakamizwa ekwelapheni umfutho wegazi ophakeme. Inomthelela omnene, ngakho-ke ingcindezi ayinciphi kakhulu. Kunemiphumela emibi embalwa."
