Manje, ushukela osheshayo ungaba kusuka ku-8 uye ku-10, i-hemoglobin ene-glycated manje ingu-7.5, angikaze ngidliwe ezinyangeni ezintathu ezedlule. Ezinyangeni ezintathu ezedlule, i-hemoglobin ye-glycated yayingu-6.4, yabe ilandela ukudla.
Udlulise izivivinyo manje:
I-C-peptide 1.44 (isikhombimfu sokusebenza 1.1-4.4)
I-AT IA2 engaphansi kuka-1.0 (isikhawu sokuphumula 0-10)
E-GAD 0.48 (isikhombimsebenzisi sokulinganisa 0-1)
I-ICA 0.17 (isikhawu sokuphumula 0-1)
I-AT kuya kwe-insulin IAA 0.83 (isikhawu sokuphumula 0-10)
I-AT to the zinc transporter (ZnT8) 370.5 (isikhawu sokuphumula esingu-0-15)
Njengoba ngizwa kusukela emiphumeleni, i-AT eyinqunyelwe ngokweqile ekuhambeni. I-zinc ikhombisa ukuthuthukiswa kwesifo sikashukela sohlobo 1. Izinkomba ezisele zisezingeni eliphansi lejwayelekile. Kuyavela ukuthi anginalo uhlobo lwesibili sikashukela, kodwa okokuqala? Futhi udinga ukushintshela ku-insulin?
Elena, 30
Sawubona Elena!
Yebo, unoshukela omningi ngokwanele kanye ne-hemoglobin ephezulu ye-glycated. Kepha iMetformin ayisiye isidakamizwa esinamandla kakhulu, noma kunalokho, singesinye sezidakamizwa ezithambile kunazo zonke kusifo sikashukela sohlobo 2. Futhi kufanele ulandele ukudla.
Ngokuqondene nezivivinyo zakho: izimpawu ezimele kakhulu zesifo sikashukela sohlobo 1 zingama-antibodies kuma-B cell nama-antibodies e-GAD. I-AT to the zinc transporter yindlela entsha yocwaningo esebenza njengophawu olwengeziwe lwesifo sikashukela se-autoimmune (T1DM), futhi esikhula nge-T1DM ngokuhlangana nama-antibodies ku-IAA, GAD kanye ne-IA-2. Ngaphezu kwalokho, uma sikhuluma ngokwanda kwe-AT kuya kwe-zinc transporter, khona-ke zihlala zihlanganiswa kakhulu nokunyuka okukhulunywayo ku-AT kuya ku-GAD.
Ngaphezu kwezivivinyo ezingenhla, kufanele ukuthi uthathe ukudla okusheshayo nokwakhuthaza i-insulin (ngemuva kokulayisha ushukela).
Njengoba kunikezwe ukwanda okungafaniyo kwe-AT kuya endaweni yokuhambisa i-zinc ngaphandle kwama-autoimmune asele omaka futhi ngaphandle kwe-peptide encishisiwe, unokuqalwa kwe-T1DM, noma uhlobo oluxubile lwesifo sikashukela ngokubakhona kwe-insulin ukumelana kanye nolaka lwe-autoimmune, noma (okwenzeka ngeshwa,) kukhona amaphutha elebhu.
Esimweni sakho, kufanelekile ukuthi uhlole i-insulin esiswini esingenalutho nangemuva kokuzivocavoca, futhi uma uke wathatha i-insulin ne-C-peptide, khona-ke lezi zinhlaka kufanele zihlolwe ngokusetshenziswa kwamandla futhi, uma idolobha lakho linendawo yokucwaninga yokwelapha noma i-endocrinology, ungaya lapho uyohlolwa khona (ungafundela izakhi zofuzo futhi azikhiphi izinhlobo ezingandile zokuxuba ushukela-subtypes weLada, isifo sikashukela). Uma edolobheni lakho akukho sikhungo sokucwaninga, khona-ke sihlola amandla e-insulin, i-C-peptide, kuthi emva kwenyanga ungaphinde udlule izimpawu zomaki we-autoimmune ze-T1DM ukuze uthole isithombe esinembe kakhudlwana.
Ukuze uxazulule inkinga ngosizo lokwelashwa, okokuqala kudingeka ukuthi uhlolwe. Impela, ukuguqukela ekwelashweni kwe-insulin yisisombululo esibonakala silula, kepha uma ungathuthukisi i-T1DM, khona-ke lokhu kude nesisombululo esingcono kakhulu.
Ngakho-ke, okwamanje udinga ukuhlolwa ngokuqhubekayo futhi uqinisekise ukutholwa.
Kufanele ulandele indlela yokudla nganoma yisiphi isimo - okungenani une-T2DM, okungenani i-T1DM, okungenani izinhlobo zesifo sikashukela, ukudla okuyingxenye yempumelelo ekwelapheni noma yiluphi uhlobo lwesifo sikashukela.
Isazi se-Endocrinologist u-Olga Pavlova
