Izidakamizwa ezokwehlisa i-cholesterol ezaziwa ngokuthi ama-statins azikwazi ukuvikela kuphela ezifweni zenhliziyo, kepha futhi zandisa namathuba okukhulisa isifo sikashukela sohlobo 2 - lena yimiphumela yocwaningo olusha.
Iziphetho zokuqala
"Sivivinye eqenjini labantu abasengozini enkulu yokuba nesifo sikashukela sohlobo lwe-2. Ngokwemininingwane yethu, ama-statin akhulisa amathuba okuthola isifo sikashukela cishe ngama-30%," kusho uDkt. Albert Einstein College of Medicine, New York.
Kepha, uyanezela, lokhu akusho ukuthi udinga ukwenqaba ukuthatha ama-statin. "Izinzuzo zale mishanguzo mayelana nokuvikela izifo zenhliziyo zinhle kakhulu futhi kufakazelwa ngokuthembekile ukuthi isincomo sethu ukuthi singayeki ukuzithatha, kodwa ukuthi labo abaziphuzayo kumele bahlolwe njalo isifo sikashukela. "
Enye ingcwethi yesifo sikashukela, uDkt Daniel Donovan, uprofesa wezokwelapha kanye nenhloko yeSikhungo Sokucwaninga Komtholampilo e-Aikan School of Medicine eMount Sinai Institute of Diabetes, Obesity and Metabolism eNew York, wavumelana nalesi sincomo.
"Sisadinga ukunquma ama-statin anama-cholesterol aphezulu" amabi. Ukusetshenziswa kwawo kwehlisa ingozi yokuthola isifo senhliziyo nge-40%, futhi isifo sikashukela singenzeka ngaphandle kwabo, "kusho uDkt Donovan.
Imininingwane yesilingo
Lolu cwaningo olusha ngukuhlaziywa kwedatha evela kolunye ucwaningo oluqhubekayo lapho iziguli zabantu abadala ezingaphezu kuka-3200 eziqhamuka ezikhungweni zikashukela zase-US ezingama-27 zibamba iqhaza.
Inhloso yalolu vivinyo ukuvikela ukukhula kwesifo sikashukela sohlobo 2 kubantu abanenkinga yokuthola lesi sifo. Bonke abahlanganyeli beqembu lokugxila ngokuzithandela bakhuluphele noma bakhuluphele. Zonke zinezimpawu zokulimaza ushukela metabolism, kepha hhayi ngezinga lokuthi zitholakala ukuthi zinesifo sikashukela sohlobo 2.
Babemenyiwe ukuthi babambe iqhaza ohlelweni lweminyaka eyi-10 lapho bekala khona ushukela wegazi kabili ngonyaka futhi babheke nokudla kwabo ama-statin. Ekuqaleni kohlelo, cishe amaphesenti amane abahlanganyeli athatha ama-statins, eduze kokuphothulwa kwawo cishe ama-30%.
Ososayensi base-Observer nabo balinganisa ukukhiqizwa kwe-insulin kanye nokumelana ne-insulin, kusho uDkt Crandall. I-insulin yi-hormone esiza umzimba uqondise kabusha ushukela kusuka ekudleni kuya kumaseli njengophethiloli.
Kulabo abathatha ama-statins, ukukhiqizwa kwe-insulin kwehle. Futhi ngokuncipha kwezinga layo egazini, okuqukethwe ushukela kuyakhuphuka. Lolu cwaningo, noma kunjalo, aluzange luveze umphumela wama-statins ekulweni ne-insulin.
Odokotela batusa
UDkt Donovan uyaqinisekisa ukuthi imininingwane etholakele ibaluleke kakhulu. "Kepha angicabangi ukuthi udinga ukulahla ama-statin. Kungenzeka ukuthi isifo senhliziyo sandulela ushukela, ngakho-ke kubalulekile ukuzama ukunciphisa ubungozi obukhona," uyanezela.
"Yize bengazange babambe iqhaza kulolu cwaningo, abantu abathola ukuthi banesifo sikashukela sohlobo 2 kufanele baqaphele kakhulu amazinga kashukela wegazi uma bethatha ama-statins," kusho uDkt Crandall. "Kunedatha encane kakhulu kuze kube manje, kepha kunemibiko ethile yokuthi ushukela ukhuphuka ngama-statins."
Udokotela ubuye aphakamise ukuthi labo abasesengcupheni yokuba nesifo sikashukela kungenzeka bathinteke ngama-statin. Lezi zici zobungozi zibandakanya ukukhulupha ngokweqile, ukuguga, umfutho wegazi ophakeme namacala esifo sikashukela emndenini. Ngeshwa, udokotela uthi, abantu abaningi ngemuva kokuthola i-prediabetes, abangazi, futhi imiphumela yocwaningo kufanele ibenze bacabange.
