IGlucobai ingumuthi olwa nesifo sikashukela. Ngingayisebenzisa ukunciphisa isisindo?

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IGlucobai (isichazamazwi somuthi - i-Acarbose) umuthi okuyiwo kuphela odambisa isifo somdlavuza okhonjwa ezinhlotsheni 1 no-2 sikashukela. Kungani ungakutholi ukusetshenziswa okubanzi njengokuthi, ngokwesibonelo, iMetformin, futhi kungani umuthi uheha kangaka kubantu abaphilile ngokuphelele, kubandakanya nabasubathi?

NjengeMetformin, iGlucobai izobe ilungile ukuthi ingashayeli umenzeli we-hypoglycemic, kodwa i-antihyperglycemic, ngoba ivimba ukwanda okusheshayo koshukela ukuphendula ama-carbohydrate ayinkimbinkimbi, kepha ayilawuli izinga le-glycemia. Ngohlobo lwesibili sikashukela, kusetshenziswa kaningi, ngokusebenza kahle kakhulu, kusebenza ngokuhambisana namanye ama-hypoglycemic agents.

Indlela yokuvezwa kwe-Glucobay

I-Acarbose iyi-inhibitor yama-amylases - iqembu lama-enzyme elibhekene nokuqhekeka kwama-molecule e-carbohydrate ayinkimbinkimbi alula, ngoba umzimba wethu uyakwazi ukusebenzisa ama-monosaccharides kuphela (ushukela, i-fructose, i-sucrose). Le nqubo iqala emlonyeni (inama-amylase wayo), kepha inqubo eyinhloko itholakala emathunjini.

IGlucobai, engena emathunjini, ivimba ukuqhekeka kwe-carbohydrate eyinkimbinkimbi kuma-molecule alula, ngakho-ke ama-carbohydrate angena emzimbeni ngokudla awangenwa ngokuphelele.

Umuthi usebenza endaweni yangakini, kuphela ku-lumen yamathumbu. Alungeni ukungena kwegazi futhi aluthinti umsebenzi wezitho nezinhlelo (kubandakanya nokukhiqizwa kwe-insulin, ukukhiqizwa kwe-glucose esibindini).

Umuthi yi-oligosaccharide - umkhiqizo wokuvutshelwa we-microorganism Actinoplanes utahensis. Imisebenzi yayo ifaka ukuvimba i-α-glucosidase, i-enzyme epancreatic ephula carbohydrate eyinkimbinkimbi ibe ngamangqamuzana alula. Ngokuvimbela ukumuncwa kwama-carbohydrate ayinkimbinkimbi, i-Acarbose isiza ukuqeda i-glucose ngokweqile futhi ibuyise i-glycemia ngokwejwayelekile.

Njengoba umuthi unciphisa ukumuncwa, kusebenza kuphela ngemuva kokudla.

Futhi njengoba ingashukumisi ama-β-cell abhekene nokukhiqizwa nokutholwa kwe-insulin yendabuko, i-Glucobai ayiziphikisi futhi.

Uboniswa ngubani umuthi

Amandla okwehla ushukela walo muthi awaziwa njengalawo ama-hypoglycemic analogues, ngakho-ke, akuyona into ewusizo ukuwusebenzisa njenge-monotherapy. Kaningi kuchazwa njenge-adjuvant, hhayi kuphela zombili izinhlobo zesifo sikashukela, kepha futhi nezimo zangaphambi kwesifo sikashukela: ukuphazamiseka kwe-glycemia okusheshayo, ushintsho ekubekezelweni kweglucose.

Ungawuthatha kanjani umuthi

E-ekhemisi chain Acarbose, ungathola izinhlobo ezimbili: umthamo ka-50 no-100 mg. Umthamo wokuqala we-Glucobay, ngokuya ngemiyalo yokusebenzisa, ungama-50 mg / usuku. Njalo ngesonto, ngokusebenza okunganele, ungathumela ngokwejwayelekile okujwayelekile kwe-50 mg, usabalalisa wonke amaphilisi kumithamo eminingana. Uma umuthi ubekezelelwa kahle yi-diabetesic (futhi kunezimanga ezanele ezingalindelekile zomuthi), khona-ke umthamo ungashintshwa u-3 r. / Day. I-100 mg ngayinye. Isilinganiso esiphezulu seGlucobay singama-300 mg / ngosuku.

Baphuza umuthi ngaphambi kokudla noma kwinqubo uqobo, baphuza ithebhulethi yonke ngamanzi. Kwesinye isikhathi odokotela bangeluleka amaphilisi okuhlafuna ngezipuni zokuqala zokudla.

Umsebenzi oyinhloko ukuletha umuthi ku-lumen we-utine omncane, ukuze kuthi lapho sekuqala ukudla i-carbohydrate, abe esekulungele ukusebenza nabo.

Uma imenyu esimweni esithile i-carbohydrate-free (amaqanda, ushizi wekhokho, inhlanzi, inyama engenasinkwa kanye nezitsha eziseceleni ngesitashi), weqa ukuthatha iphilisi. I-Acarbose ayisebenzi endabeni yokusebenzisa ama-monosaccharides alula - ushukela omsulwa, i-fructose.

Kubalulekile ukungakhohlwa ukuthi ukwelashwa nge-acarbose, njenganoma yisiphi esinye isidakamizwa esidalwa yisifo sikashukela, akukubeki esikhundleni sokudla okune-carb ephansi, umsebenzi owanele womzimba, ukulawula isimo somzwelo, kanye nokubambelela kokulala nokuphumula. Umuthi kumele usizwe nsuku zonke kuze kube yindlela yokuphila entsha eba umkhuba.

Umphumela we-antihyperglycemic we-Glucobay awunamandla, ngakho-ke uvame ukubekwa njengethuluzi elingeziwe ekwelapheni okuyinkimbinkimbi. Njengoba sekushiwo, umuthi uqobo ngokwawo awubangeli i-hypoglycemia, kepha ekwelashweni okuyinkimbinkimbi nezinye izidakamizwa ze-hypoglycemic, imiphumela enjalo iyenzeka. Bayamisa ukuhlaselwa hhayi ngoshukela, njengoba kujwayelekile ezimweni ezinjalo, - isisulu kufanele sinikezwe kalula ama-carbohydrate okugaya kuwo, lapho i-acarbose isabela khona.

Izinketho zemiphumela emibi

Njengoba i-acarbose ivimbela ukumuncwa kokudla kwe-carbohydrate, eyokugcina inqwabelana kwikholoni bese iqala ukubila. Izimpawu zokuvutshelwa ziboniswa ngesimo sokwakheka kwegesi, ukuqhuma, ukushaya ikhwela, ukuqhakaza, izinhlungu kule ndawo, ukuhudula. Ngenxa yalokhu, umuntu onesifo sikashukela uyesaba ngisho nokuphuma endlini, njengoba ukungalawulwa kwesitulo kudangala ngokokuziphatha.

Ukungajabuli kuyakhula ngemuva kokufakwa kokudla okugcwele ama-carbohydrate asheshayo, ikakhulukazi ushukela, emgodini wokugaya ukudla futhi kunciphisa uma ama-carbohydrate angangeneki kalula. IGlucobai isebenza njengohlobo lwenkomba yama-carbohydrate ngokweqile, ibeka umkhawulo wayo kulolu hlobo lwezakhi. Ukuphendula kwesitho ngasinye kungumuntu ngamunye, kungenzeka kungabikho uguquko oluphelele esiswini uma ulawula ukudla kwakho nesisindo.

Abanye ochwepheshe baqhathanisa indlela yokusebenza kwe-Glucobay nokwelashwa kokuncika kotshwala obungapheli: uma isiguli sizama ukubuyela enkambisweni yaso embi, lokhu kuholela ezinkomba zokuthi ubuthi obukhulu bomzimba.

Ngaphezu kwe-í-glucosidase, umuthi uvimbela amandla okusebenza kwe-lactase, i-enzyme ebhubhisa i-lactose (ushukela wobisi) ngo-10%. Uma umuntu onesifo sikashukela eke wabona umsebenzi owancishisiwe we-enzyme enjalo, ukungabekezelelani kwemikhiqizo yobisi (ikakhulukazi ukhilimu nobisi) kuzothuthukisa lo mphumela. Imikhiqizo yobisi ngokuvamile kulula ukuyigaya.

Izinkinga eziphansi kakhulu ze-dyspeptic kakhulu ukusabela komzimba wesikhumba nokuvuvukala.

Njengazo izidakamizwa zokwenziwa eziningi, kungaba ukuqhuma kwesikhumba, ukulunywa, ubomvu, kwezinye izimo - ngisho ne-edema kaQuincke.

Contraindication kanye analogues for acarbose

Musa ukunquma iGlucobai:

  • Iziguli ezinomdlavuza wesibindi;
  • Nge-ulcerative colitis;
  • Uma kwenzeka ukuvuvukala kwamathumbu (kwifomu elinamandla noma elingamahlalakhona);
  • Isifo sikashukela nge-hernia (inguinal, femoral, umbilical, epigastric);
  • Omama abakhulelwe futhi abancelile;
  • Nge-malabsorption syndrome;
  • iziguli ezinama-pathologies wezinso ezingamahlalakhona.

Kunezimpawu ezimbalwa ze-Glucobay: ngokuya ngesakhi esisebenzayo (i-acarbose), singathathelwa indawo yi-Alumina, nangomphumela wezokwelapha - yi-Voxus.

I-Glucobay yokunciphisa umzimba

Iningi labantu emhlabeni kungenzeka lijabule ngesisindo sabo nangesibalo sabo. Kungenzeka yini ukuvimba ukumuncwa kwama-carbohydrate kuma-non-diabetes uma ngabe ngonile ngokudla? Abakhi bomzimba balulekwe ukuba "bakhiphe ikhekhe noma baphuze iphilisi le-Glucobay." Ivimbela ama-pancreatic amylases, iqembu lama-enzyme adiliza ama-polysaccharides kuma-analog ama-mono. Konke okungafunwanga ngamathumbu, kudonsela amanzi kuwo, kuvuselela uhudo olungabonakali.

Futhi izincomo ezikhethekile manje: uma ungakwazi ukwenqaba amaswidi namakhekhe, yidla amaphilisi amabili noma amabili we-Acarbose (50-100 mg) ngaphambi komthamo olandelayo wama-carbohydrate. Uma uzwa sengathi udla kakhulu, ungaginya enye ithebhulethi engu-50 mg. Isifo sohudo esinjalo "kokudla" okunjalo, kepha asilawulwa njengokwehliswa kwesisindo, ngokwesibonelo, nge-orlistat.

Ngakho-ke ingabe kukufanele yini "ukujwayela i-chemistry" uma ukwazi ukubhalisela ukudla okungenamsoco ngemuva komkhosi omkhulu weholide? Kuzothuthukiswa i-gag Reflex kungakapheli inyanga, futhi uzokhokhisa noma yiliphi ithuba, noma ungabi namanzi neminwe emibili. Kunzima futhi kuyabiza ukwelapha ama-pathologies anjalo, ngakho-ke kulula ukusebenzisa amathumbu inqubo yokunciphisa isisindo.

I-Acarbose iyatholakala, inemiphumela emincane okungenani, isiza ukulawula i-carbohydrate.

Glucobay - ukubukeza kwabanesifo sikashukela

U-Anton Lazarenko, uSochi "Ngubani onendaba, ngibika ngokusetshenziswa kwe-ascarbose izinyanga ezimbili. Kuqale ngethamo elilinganiselwe lama-50 mg / ngasikhathi, lakhula kancane kancane laya ku-100 mg / ngasikhathi, njengoba kushiwo kwimiyalo. Ngaphezu kwalokho, ngesikhathi sasemini, ngisale nethebhulethi yaseNovonorm (4 mg). Le setha ingivumela ukuthi ngilawule ngisho noshukela ntambama: emahoreni angama-2-3 ngemuva kokugcwala (ngokwezindinganiso zikashukela) kwasemini ku-glucometer - kungabi ngaphezu kuka-7 nohhafu mmol / l. Phambilini, babengaphansi kuka-10 ngaleso sikhathi abengekho. "

IVitaliy Alekseevich, esifundeni saseBryansk “Ishukela lami seligugile. Lokho ushukela ekuseni kwakujwayelekile, ngiphuza kusihlwa uGlyukofazh Long (1500 ml), futhi ekuseni - kuya eTrazhent (4 mg). Ngaphambi kokudla, ngiphuza nethebhulethi yaseNovonorm ngaso sonke isikhathi, kodwa ayibambeki ushukela kahle. Ubuye wengeza enye i-100 mg yeGlucobai ngesidlo sasemini, ngoba amaphutha ekudleni ngalesi sikhathi ayephezulu (i-beet, izaqathe, amazambane). I-Glycated hemoglobin manje ingu-5.6 mmol / L. Akunandaba ukuthi babhala ini kumazwana, umuthi unendawo yawo ohlwini lwemithi yokulwa nesifo sikashukela, futhi akufanele usilahle eshalofini eliphezulu. ”

U-Irina, eMoscow "E-Glyukobay, intengo yethu ingama-ruble ayi-670-800, kungenzeka ukuthi angelaphe isifo sikashukela, kepha angasonakalisa. Ngiyisebenzisa njengethuluzi lesikhathi esisodwa uma kunesidingo ekuncepheni ama-carbohydrate esimweni esingajwayelekile (endleleni, ephathini, ephathini yenhlangano). Kepha ngokuvamile, ngihamba ngeMetva Teva futhi ngizama ukugcina ukudla. IGlyukobay ngeMetformin, vele, ayinakuqhathaniswa, kodwa ngicabanga ukuthi amandla ayo njenge-blocker yesikhathi esisodwa asebenza kakhulu kuneMetformin Teva. "

Ngakho-ke ingabe kufanelekile noma akukufanele ukuthatha i-Glucobai? Ake siqale ngezinzuzo ezingenamkhawulo:

  • Umuthi awungenwa egazini futhi awunamphumela omzimba emzimbeni;
  • Akukhuthazi ukuvela nokuqhekeka kwe-insulin yayo uqobo, ngakho-ke akukho-hypoglycemia phakathi kwemiphumela emibi;
  • Kusungulwe ngesilingo ukuthi ukusetshenziswa isikhathi eside kwe-acarbose kunciphisa kakhulu izinga le-cholesterol "embi" kanye nezinga lokuqhubeka kwesifo sokuqina kwesifo sikashukela;
  • Ukuvinjwa kokufakwa kwe-carbohydrate kusiza ukulawula isisindo.

Kunobunzima abambalwa: ukungasebenzi kahle nokungafaneleki kwe-monotherapy, kanye nemiphumela emibi ebekiwe ngendlela yokuphazamiseka kwengqondo okuyi-dyspeptic, yona esiza ukulawula isisindo nokudla.

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