Umuthi i-Diabeteson, okuhloswe ngawo ukwelapha isifo sikashukela, unomphumela wemithi we-hypoglycemic.
Inikeza ukukhuthaza kwe-insulin secretion, kunciphisa isikhathi sesikhathi ukusuka ekudleni kuya kumjovo.
Inempahla yokwandisa ukuzwela kwezicubu ezibuthakathaka kuyi-hormone, okwenza kube nomphumela we-insulin secretory of glucose. Intengo yesifo sikashukela incane impela uma iqhathaniswa nama-analogues.
Izici ze-Pharmacological
Ingxenye esebenzayo ye-Diabeteson yi-gliclazide. I-ejenti yomlomo ye-hypoglycemic, ehlukile kuma-analogues lapho kukhona indandatho ye-heterocyclic.
Umuthi ukhuphula izinga le-insprandial insulin, ngemuva kwalokho ukucashelwa kwe-C-peptide kuphikelela iminyaka emibili ngemuva kokuphatha.
Ithebhulethi Diabeteson MV 60 mg
Futhi inezici ze-hemovascular ambazo zinciphisa i-microthrombosis ngamasu amabili okungenza ukuthi uma izingqinamba zesifo sikashukela zingabandakanyeka.
Abathola i-Diabeteson yilaba: hypromellose, colloidal silicon dioxide, i-magnesium stearate, i-lactose, i-maltodextrin.
Izinkomba zokusetshenziswa
Isetshenziselwa uhlobo lwe-II yesifo sikashukela esimweni lapho kungenakwenzeka ukulawula izinga le-glycemia kuphela ngokudla, ukunciphisa isisindo, noma ukuvivinya umzimba.
Imithamo nokuphatha
Isifo sikashukela senzelwe kuphela ukusetshenziswa komlomo futhi singasetshenziswa kuphela ezigulini ezingaphezu kweminyaka eyi-18.
Umthamo wansuku zonke okungenani okungenani ungama-30 milligrams, awukwazi ukwedlula amaphilisi amabili.
Umthamo unqunywa udokotela ohambela yedwa kuphela. Inani lansuku zonke lomuthi lingasetshenziswa kanye ngesikhathi sokudla kokuqala. Uma ngesizathu esithile isiguli sikhohliwe ukuphuza iphilisi, umthamo wansuku zonke akufanele wengezwe ngosuku olulandelayo.
Kokusetshenziswa kokuqala, kunconyelwa ukusebenzisa umthamo wama-milligram angama-30, okuyingxenye yethebhulethi ye-Diabeteson. Lapho ukulawulwa ngempumelelo kweglucose kutholakala, ukwelashwa kungaqhubeka ngaphandle kokukhulisa inani lemithi.
Uma kunesidingo sokwandisa umthamo, kunconyelwa ukuba usinyusele kuma-milligram angama-60. Leli nani liqukethe kuthebhulethi eyodwa yeDiabetes.
Futhi, uma kunesidingo, ingakhushulwa ibe ngu-90, noma ize ibe ngamamiligrama angama-120. Lokhu kulingana namathebulethi amabili athathwe kanye ngesikhathi sokudla kwasekuseni
Umthamo awukwazi ukwandiswa ngokushesha, lokhu kufanele kwenziwe kuphela ngemuva kwesikhathi esithile, esivame ukulingana nezinsuku ezingama-30. Kepha lokhu akusebenzi ezimweni lapho bekungekho ukwehla kweglue ngemuva kwezinsuku eziyi-14.
Ezimweni ezinjalo, umthamo ungandiswa ngaphambili. Inani lansuku zonke lomuthi othathwe kuleli cala lizoba ngama-milligram angama-60. Ezigulini esezikhulile, kunconywa umthamo wansuku zonke wama-milligram angama-60, okufanele uphuzwe kanye ngesikhathi sokudla kokuqala. I-Diabeteson ingathathwa ihlanganiswa nezinye izidakamizwa ze-antidiabetes: i-biguanides, i-α-glucosidase inhibitors ne-insulin.
Kufanele kukhunjulwe ukuthi ukusetshenziswa okuhlangene kwalesi sidakamizwa nge-hormone ekhonjisiwe kungavunyelwa kuphela uma kungekho ukulawula okwanele kweglucose yegazi.
Ukwelashwa okunjalo kufanele kwenzeke ngaphansi kokuqashwa kongoti.
Ezigulini ezisengozini ye-hypoglycemia, umthamo wansuku zonke odingekayo angama-milligram angama-30. Abantu abanenkinga yokuhluleka kwe-renal ngokulinganisela kuya kokuqala kufanele baqale ukwelashwa ngama-milligrams angama-60, kepha isiguli kufanele sibe ngaphansi kokuqashwa kodokotela.
Kulabo abahlushwa yizifo ezinzima ze-vascular, ezifana nesifo senhliziyo (i-coronary heart isifo (CHD)), faka izilonda ze-vascular, isifo esibucayi se-coronary artery, umthamo wansuku zonke ungama-milligram angama-30.
Ukweqisa
Uma weqa inani eliphakeme elivumelekile lomuthi, okungamacwecwe amabili (ama-milligram angama-120), i-hypoglycemia ingavela ngaphandle kokulahlekelwa ukwazi noma ukuphazamiseka kwemizwa.
Lezi zimpawu zidinga ukulungiswa ngokudla kwemikhiqizo equkethe ushukela, ushintsho ekudleni nasekudla. Kuze kube yilapho umzimba uzinze ngokuphelele, ukuqapha ngokucophelela isimo sesiguli kuyadingeka.
Endabeni ye-hypoglycemia enzima, ingahambisana nezinkinga ezinzima ngendlela:
- ukuphazamiseka kwemizwa;
- ukubanjwa
- coma
Kulokhu, ukunakekelwa okuphuthumayo kokulashwa kanye nokwelashwa kwesiguli ngokushesha kuyadingeka.
Uma kusolwa ukuthi kudalwa i-hypoglycemic coma, isiguli kufanele siphathe ama-milliliters angama-50 wesisombululo se-glucose esigxile ku-20-30%. Esikhathini esizayo, yethula isixazululo esingahlali sigxile esilingana ne-10% ngomvamisa odingekile ukuze kulondolozwe amazinga eglucose angaphezu kuka-1 g / l.
Imiphumela emibi
Ngesikhathi sokusebenzisa isidakamizwa i-Diabeteson, imiphumela elandelayo emibi emzimbeni ingenzeka:
- ukunaka kokuphazamiseka kwengqondo;
- ukwephulwa kokuzwela;
- umuzwa onamandla wendlala;
- umbono nokukhubazeka;
- isimo esijabulile;
- ukuphefumula okungashonile;
- ukudideka kokwazi;
- ukulahlekelwa ukuzithiba;
- ukusabela okuphazamisekile;
- umphumela obulalayo;
- Isiyezi
- ukuphazamiseka kokulala;
- ikhanda
- i-bradycardia;
- ukozela
- ukulahlekelwa amandla;
- Ukudana
- ubuthakathaka
- iminyakazo
- delirium;
- isicanucanu
- i-aphasia;
- paresis;
- ukuthuthumela.
Ngaphezu kwezimpawu ezijwayelekile, izimpawu zokuphikisana nomthetho we-adrenergic zingavela:
- i-arterial hypertension;
- izibuko
- ukujuluka ngokweqile;
- ukuhlaselwa kwe-angina;
- umuzwa wokukhathazeka;
- isikhumba esiminyene;
- i-tachycardia;
- arrhythmia.
Eminye imiphumela emibi ingavela kusuka ku:
- ipheshana esiswini: isicanucanu: ukugabha, uhudo, ukuqunjelwa, i-dyspepsia, Ubuhlungu besisu;
- isikhumba nezicubu ezingaphansi: i-pruritus, i-erythema, ukuqunjelwa okuxutshana nokuqina, ukuqunjelwa kwama-macropapular, i-pruritus, i-erythema, i-rash, i-urticaria;
- amasistimu egazi: thrombocytopenia, granulocytopenia, anemia, leukopenia, thrombocytopenia;
- uhlelo lwe-hepatobiliary: i-hepatitis, ama-enzyme aphezulu wesibindi;
- izitho zombono: ukuphazamiseka kwesikhashana kubukhali.
Uma usebenzisa noma yisiphi isidakamizwa se-sulfonylurea, ungahle uthole:
- amacala erythrocytopenia;
- i-vasculitis ye-allergic;
- i-hemolytic anemia;
- i-agranulocytosis;
- pancytopenia.
Contraindication
Umuthi awunqunyelwe ukuthi:
- ukucaphuka;
- ukwehluleka okunzima kwezinso;
- isifo sikashukela;
- ngaphansi kweminyaka eyi-18;
- ukwehluleka kwesibindi okunzima;
- isimo ngaphambi kokuphela kwesifo sikashukela;
- isifo sikashukela sikashukela;
- ukukhulelwa
- I-hypersensitivity to gliclazide nezinye izitho eziyingxenye yomuthi.
Intengo
Inani eliphakathi lomuthi i-Diabeteson MV 60 mg:
- eRussia - kusuka ku-329 rub. I-Diabeteson MV amaphilisi ama-milligram angama-60 No 30;
- e-Ukraine - kusuka ku-91.92 UAH. I-Diabeteson MV amaphilisi ama-milligram angama-60 No 30.
Amavidiyo ahlobene
Konke okudingeka ukwazi mayelana nokusebenzisa isidakamizwa i-Diabeteson kuvidiyo:
I-Diabeteson umuthi ohloselwe ukwelashwa kwesifo sikashukela sohlobo 2. Ukubuyekezwa kukhombisa ukusebenza kahle kwayo nokubonakaliswa okungathandeki kwemiphumela emibi, kepha abaningi abajabule ngentengo ephakeme. Kuyatholakala ngesimo sethebhulethi. Umuthi unomphumela we-hypoglycemic.
