Isilawuli seMetabolism Tiogamma: imiyalo esetshenziswayo, intengo, ukuqondana nokubuyekezwa komuthi

Kuyaziwa ukuthi inkambo yesifo sikashukela isongela ukuthuthukiswa kwezinkinga eziningi, ezigcina ziphenduka izifo ezinqala.

Ukuphazamiseka kwemetabolic kuthinta zonke izitho, kufaka phakathi izinzwa. Izinkinga ezinjengesifo sikashukela njenge-polyneuropathy, ukulimala kwesibindi namanye ama-pathologies akhula.

Izifo ezinjalo ziphathwa ngempumelelo umuthi onelungelo lobunikazi u-Tiogamma, imiyalo yokusetshenziswa kwayo ehlukile ngokuya ngesimo sokukhishwa kwe-pharmacological.

Izinkomba zokusetshenziswa

Enye yezingqinamba eziphikisayo zemithi futhi kuseyindlela yokwelashwa kwezinkinga zesifo sikashukela. Ezinye izidakamizwa zithinta kuphela izimpawu zokwanda kwesifo sikashukela.

Kodwa indlela esezingeni eliphezulu kakhulu ithonya ngqo kuyi-pathogenesis yesifo. Enye yezinkinga ezivame kakhulu zesifo sikashukela yi-polyneuropathy.

Lokhu kudalwa kwengqondo kuholela enkingeni yemilenze (unyawo lwesifo sikashukela) futhi kusongela nangokunqunywa kwezingalo. Umnyombo walesi sifo okuqukethwe ushukela okungajwayelekile emangqamuzaneni enza iziphetho zezinzwa nemithambo yegazi: ama-ejensi ayonakalisa i-oxidizing - okuyi-free radicals - akhiwa kuwo.

Ungayinqamula kanjani le nqubo? Isixazululo ukugcina amazinga ajwayelekile kashukela. Enye yezinto ezilwa ngempumelelo nezifo ezinjalo yi-thioctic (TK) noma i-α-lipoic acid (ALA). I-Thioctic acid ibandakanyeka ngempumelelo ku-metabolism, inciphisa ngempumelelo i-acidity yamaseli, ekubeni yi-antioxidant enamandla.

I-Thiogma kusixazululo kanye namathebulethi

Ngaphezu kwalokho, i-TC iguquguqula ngokwejwayelekile umzimba we-carboxylic acid, ivikela ama-hepatocytes wesibindi. I-ALA yandisa ukuvunyelwa kwamaselula kwe-insulin, edlala indima enkulu kushukela. Namuhla, ithuluzi elihlukile elisuselwa ku-thioctic acid, iT Thiogamma, livelile emakethe.

Lo muthi unobungane nomzimba, ngoba i-ALA uqobo ingumkhiqizo wemvelo we-metabolic. Ithinta kakhulu izinqubo ze-metabolic, lo muthi wehlisa ukuthuthukiswa kwezinkinga futhi wenze buthaka izimpawu zabo. Esikhathini sikashukela, i-thiogamma inganciphisa ngisho nethamo lemithi ekwehlisa ushukela.

Umuthi uphatha ngempumelelo:

• isifo sikashukela se-neuropathy;
• ukudakwa kakhulu;
• i-polyneuropathy yotshwala kanye ne-peripheral polyneuropathy;
• ukonakala kwamafutha we-hepatocytes (ngokwesibonelo, ngotshwala) kanye nezinye izindlela zesibindi.

Ukwakheka

Isakhi esiyinhloko yi-thioctic acid (TC). Umthamo onconywayo wokwelapha ngu-600 mg / ngosuku.

Ukugxila kwe-infusion kuqukethe:

• i-meglumine theoctate (into eyisisekelo) - ifana ne-600 mg ye-TC;
• i-macrogol (4000 mg) ne-meglumine (kufika ku-18 mg);
• amanzi d / i - 20 ml

Isixazululo sokungenelela (ifomu eliqediwe) lifaka:

• usawoti we-meglumine we-TC (into eyisisekelo) - uhambelana no-600 ml we-thioctic acid;
• i-macrogol ne-meglumine;
• amanzi d / i - 50 ml.

Ifomu lethebhulethi liqukethe:

• TK - 600 mg;
• i-microcrystalline cellulose ne-lactose monohydrate - 49 mg ngayinye;
• i-sodium caramellose - 16 mg;
• i-magnesium stearate - 16 mg ne-talc - 2 mg.

Igobolondo yethebhulethi ifaka:

• i-talc - 2.0 mg;
• i-macrogol - 0,6 mg;
• i-hypromellose - 2.8 mg;
• sodium lauryl sulfate - cishe 0, 025 mg.

Khipha ifomu nokufakwa

Emakhemisi, iTiogamma ivezwa ngalezi zinhlobo ezilandelayo:

• ukulungele ukusetshenziswa, isixazululo somjovo esinombala osobala okusobala ezilwaneni. Inombala ophuzi ophuzi. Amabhodlela angama-50 ml enziwe ngengilazi emdaka futhi embozwe ngesithinteli senjoloba, esivikelwe ngaphezulu nge-aluminium cap. Ngasinye sinesikhwama sepulasitiki esikhanyayo. Iphakheji liqukethe amabhodlela angafika kwabayi-10 ahlukaniswe yikhadibhodi ukwahlukanisa;
• gxilisa ukumnika - esobala kuma-ampoules angama-20 ml. Inombala ophuzi ophuzi. I-ampoule ngayinye yenziwa ngengilazi evikela ukukhanya ansundu futhi imakwe ichashaza elimhlophe. Ipuleti lekhadibhodi elinezingxenye ezihlukanisayo lenzelwe ama-ampoules ayi-5. Iphakethe lingaba namapuleti ayi-1,2 noma ama-4;
• i-biconvex noma amaphilisi we-oblong ka-600 ml lilinye. Izingcezu eziyi-10 zigcwele amapuleti we-foil noma wePVC blister. Banombala ophuzi okhanyayo. Kunobungozi ezinhlangothini zombili. Isisekelo sokukhanya okuphuzi siyabonakala ekuphumeni kwethebhulethi. Ukupakisha ngesimo sebhokisi lamakhadibhodi aqukethe ama-3, 6 noma ama-10 blims.

Isenzo se-Pharmacological

Isakhi esiyinhloko yi-thioctic acid. Ikhiqizwa ngumzimba onempilo futhi ibandakanyeka ngentshiseko emzimbeni we-fat, oxidative ne-carbohydrate metabolism emzimbeni.

Ukubandakanyeka ku-lipid metabolism, i-TC inciphisa ukujikeleza kwamafutha aphansi kakhulu, ngenxa yokuthi inani lama-lipid aphezulu kakhulu kwi-plasma yegazi likhuphuka.

Ngakho-ke i-thioctic acid ikhulula imithambo yegazi kumaseli amaningi ngokweqile. I-TK inomphumela omuhle kakhulu wokudedelwa. Leli khono le-thioctic acid liwumphumela wokusebenza kahle kwesibindi.

I-Thiogma isetshenziswa futhi ngenkuthalo ekwelashweni kwesifo sikashukela, ithuthukisa umsoco wezinzwa ezinesifo sezinzwa Kwehlisa ukuqina kwamaseli ku-glucose futhi kuvimbela ukunqwabelana kwe-glycogen esibindini, ngokuba yi-hepatoprotector enhle kakhulu. Izici ze-pharmacological zomuthi ziyafana nesenzo se-Vitamin B.

Umuthi futhi uthandwa kakhulu ku-cosmetology. Njengoba i-alpha lipoic acid inomphumela omuhle esikhumbeni sobuso, yona:

• kunciphisa imibimbi, ngisho nezimpawu zobuso ezijulile;
• kuthoba isikhumba;
• ikhulula izinduna.

Imiyalo yokusebenzisa

Imithetho yokuphuza umuthi iyahluka ngokuya ngesimo sokukhululwa.

Kunconywa amaphilisi angu-600 mg ukuthi athathwe kanye ngosuku.

Ukuze ungalimazi igobolondo, akufanele lihlafunwe. Ukugeza ngamanzi. Inkambo yokwelapha ichazwa udokotela ngokuya izinkomba ngazinye.

Imvamisa amaphilisi adakwa kusuka enyangeni kuya ezinsukwini ezingama-60. Phinda ukwelashwa izikhathi ezi-2-3 ngonyaka. Uma i-Thiogamma isetshenziswa njenge-infusion (ukumfaka ngaphakathi), umthamo wayo ngosuku nawo uyi-600 mg. I-TC engaka nje iqukethwe ku-ampoule ngayinye, elula kakhulu.

Umuthi uphathwa kancane, kuze kube yisigamu sehora, ukuqeda imiphumela emibi. Ukwelapha kuleli cala kuthatha amasonto angama-2-4. Izikhathi zokwelashwa ezimfushane (kuqhathaniswa namathebulethi) zichazwa yi-digestibility ephezulu yomuthi ngeplasma yegazi.

Ukulungiselela isixazululo sokufakwa kokunye okugxilwe kukho, kufanele wenze okulandelayo: okuqukethwe i-ampoule eyodwa kuxutshaniswe ne-100-250 ml yesisombululo se-sodium chloride (9%).

Ingxube ebangelwa imbozwe ngokushesha ngecala lekhethelo ekhethekile futhi iphathwe njenge-dropper ye-intravenous.

Inqubo ithatha imizuzu engama-20 kuye kwengama-30. Isixazululo seTogogamm esenziwe ngomumo singagcinwa amahora afinyelela kwayi-6.

Contraindication

Ukuxhumana ngokusetshenziswa kweTiogamma kufaka phakathi:

• i-pathology yesibindi;
• ubungozi be-lactic acidosis (ikakhulukazi nge-drip infusions);
• isilonda sesisu;
• isifo senhliziyo
• ukomisa;
• isifo sikashukela
• uphuzo oludakayo;
• imivimbo
• ukumuncwa kwamathumbu ompofu (lapho usebenzisa amaphilisi);
• ukwanda kwe-myocardial infarction;
• ubuntwana;
• ukukhulelwa
• ukungabekezeleli ezintweni eziyinhloko: ukutholwa, noma ifa.

Imiphumela emibi

Ngesikhathi sokwelashwa ngemiphumela emibi yezidakamizwa kungenzeka:

• dyspepsia
• kuyaqabukela (ngemuva kokudonsa) izicubu zemisipha zingabonakala;
• ukukhanda kwekhanda (imvamisa kuyamisa lapho ukumnika kuhamba kancane);
• i-thrombophlebitis;
• ukwephula ukunambitheka;
• ubomvu endaweni yokujova (urticaria);
• ukungaboni kahle (onesifo sikashukela).

Ukuxhumana neminye imithi

I-Thiogma ngokuhambisana nezinye izidakamizwa inomphumela olandelayo:

• umphumela wokulwa nokuvuvukala we-glucocorticoids uyathuthukiswa;
• izidakamizwa ze-hypoglycemic zithuthukisa umphumela wokwelapha. Ngakho-ke, ukusetshenziswa kwabo okuhlanganyelwe neTiogamma kufaka ukulungisa ukulungisa imithamo ukuze unciphise;
• IThorogma ayihambelani nezixazululo ze-Dextrose neCisplacin.

Imibandela yokuthengisa, yokugcina nokugcina eshalofini

Umuthi usatshalaliswa kwifomu eliqinisekisiwe le-receptor. Ekamelweni elimnyama nelomile, lokushisa lika-20-25 ° C. Ukufakwa akumelwe konakaliswe. Impilo yeshelf umuthi iminyaka emi-5.

Imiyalo ekhethekile

Ukwelashwa kwesifo sikashukela ngeTiogamma kufaka ukulungiswa komthamo we-insulin owawunqunywe ngaphambilini.

Umuthi unomphumela oqinile we-tonic ne-antioxidant, ngakho-ke ungasetshenziswa njengomkhiqizo wokugcoba.

Kufanele ithathe isimo ngesimo samabhodlela (hhayi ukugxilisa ingqondo). Okuqukethwe, ngaphandle kokufaka, kungafakwa ngokushesha esikhunjeni. Kumele ihlanzwe ngaphambi komphumela osebenza kahle womuthi.

Intengo nokuthi ungayithenga kuphi

Izindleko zomuthi ezilinganisweni ezingama-600 mg ziyahlukahluka ngokuya ngesimo sokukhishwa.

Ngakho-ke amanani entengo eTiogamma eRussian Federation ngala alandelayo:

• gxila (ibhodlela eli-1) - ama-ruble angama-210;
• isisombululo se-droppers (i-1 ampoule) - ama-ruble angama-200;
• amaphilisi (i-pack of 30 pcs.) - ama-ruble angaba ngu-850.

Ungathenga iTiogamma kunoma iyiphi ikhemisi noma i-oda online.

Ama-Analogs (amaRussia nawangaphandle)

Izidakamizwa ezinjalo ezifuywayo zifaka phakathi: iCorilip ne-Oktolipen, i-Lipothioxone. Izilimi zezangaphandle (zaseJalimane): Thioctacid, Berlition.

Sebenzisa ngesikhathi sokukhulelwa, ebuntwaneni nasekugugeni

Ngesikhathi sokukhulelwa, ukuthatha umuthi akufiseleki, ngoba umphumela ongemuhle ku-fetus kungenzeka.

Umuthi uvunyelwe ngokuphelele ezinganeni ngenxa yezinkinga ezinkulu ezigulini ezincane. Kunikezwa umuthi kubantu asebekhulile abanesifo sikashukela sohlobo 2.

Ngotshwala

I-Alcohol yenza buthaka umphumela wesidakamizwa, ngakho-ke ukusetshenziswa kwe-ethanol enqubo yokwelashwa akunconywa.

Ukubuyekezwa

Kuyadingeka futhi phakathi kweziguli ezithambekele kuma-neuropathies, ngoba isebenza njenge-prophylaxis kanye nokwelashwa kwalezi zifo ze-pathologies futhi kukuvumela ukuthi ulondoloze umthamo wokusebenza iminyaka eminingi.

Ngaphezu kwalokho, umuthi (okwesikhashana) usiza ukugwema ukuthuthukiswa kwezifo ze-endocrine. Ngokuya kokubuyekezwa, kuyaphawuleka ukuthi asikho isidingo sokwesaba imiphumela emibi yalo muthi, ngoba ukubonakaliswa kwawo akuvamile kakhulu.

Amavidiyo ahlobene

Mayelana nokusetshenziswa kwe-alpha-lipoic acid ekwelapheni i-neuropathy yesifo sikashukela kuvidiyo: